Drug Targeting And Delivery

Drug Targeting And Delivery Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Drug Targeting And Delivery book. This book definitely worth reading, it is an incredibly well-written.

Targeted Drug Delivery : Concepts and Design

Padma V. Devarajan,Sanyog Jain
Targeted Drug Delivery Concepts and Design Book PDF

Author : Padma V. Devarajan,Sanyog Jain
Publisher : Springer
Page : 788 pages
File Size : 51,9 Mb
Release : 2014-12-08
Category : Medical
ISBN : 9783319113555

Get Book

Targeted Drug Delivery : Concepts and Design by Padma V. Devarajan,Sanyog Jain Pdf

This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.

Targeted Drug Delivery

Rachael W. Sirianni,Bahareh Behkam
Targeted Drug Delivery Book PDF

Author : Rachael W. Sirianni,Bahareh Behkam
Publisher : Humana Press
Page : 230 pages
File Size : 47,5 Mb
Release : 2018-07-27
Category : Medical
ISBN : 1493986597

Get Book

Targeted Drug Delivery by Rachael W. Sirianni,Bahareh Behkam Pdf

This volume looks at the latest techniques used to enable therapeutic molecules to be targeted for site-specific delivery. The chapters in this book discuss topics such as approaches to express biologically derived and synthetic nanocarriers; strategies to assist in nanocarrier targeting to specific cells and tissues; and methods for evaluating delivery and efficiency for new classes of agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Targeted Drug Delivery: Methods and Protocols is a valuable resource for anyone interested in understanding the diversity of methods used in this evolving field.

Drug Targeting and Stimuli Sensitive Drug Delivery Systems

Alexandru Mihai Grumezescu
Drug Targeting and Stimuli Sensitive Drug Delivery Systems Book PDF

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 836 pages
File Size : 55,6 Mb
Release : 2018-05-21
Category : Science
ISBN : 9780128136904

Get Book

Drug Targeting and Stimuli Sensitive Drug Delivery Systems by Alexandru Mihai Grumezescu Pdf

Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective drug delivery systems. Shows how the use of nanomaterials can help target a drug to specific tissues and cells Explores the development of stimuli-responsive drug delivery systems Includes case studies to showcase how stimuli responsive nanosystems are used in a variety of therapies, including camptothecin delivery, diabetes and cancer therapy

Smart Drug Delivery System

Ali Demir Sezer
Smart Drug Delivery System Book PDF

Author : Ali Demir Sezer
Publisher : BoD – Books on Demand
Page : 400 pages
File Size : 54,5 Mb
Release : 2016-02-10
Category : Medical
ISBN : 9789535122470

Get Book

Smart Drug Delivery System by Ali Demir Sezer Pdf

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Multifunctional Nanoparticles for Drug Delivery Applications

Sonke Svenson,Robert K. Prud'homme
Multifunctional Nanoparticles for Drug Delivery Applications Book PDF

Author : Sonke Svenson,Robert K. Prud'homme
Publisher : Springer Science & Business Media
Page : 371 pages
File Size : 50,5 Mb
Release : 2012-02-22
Category : Technology & Engineering
ISBN : 9781461423058

Get Book

Multifunctional Nanoparticles for Drug Delivery Applications by Sonke Svenson,Robert K. Prud'homme Pdf

This book clearly demonstrates the progression of nanoparticle therapeutics from basic research to applications. This book, unlike others covering nanoparticles used in medical applications, presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy.

Drug Delivery and Targeting

Anya M. Hillery,Andrew W. Lloyd,James Swarbrick
Drug Delivery and Targeting Book PDF

Author : Anya M. Hillery,Andrew W. Lloyd,James Swarbrick
Publisher : CRC Press
Page : 448 pages
File Size : 46,5 Mb
Release : 2003-09-02
Category : Medical
ISBN : 9780203302767

Get Book

Drug Delivery and Targeting by Anya M. Hillery,Andrew W. Lloyd,James Swarbrick Pdf

The advances in biotechnology and molecular biology over recent years have resulted in a large number of novel molecules with the potential to revolutionize the treatment and prevention of disease. However, such potential is severely compromised by significant obstacles to delivery of these drugs in vivo. These obstacles are often so great that effective drug delivery and targeting is now recognized as the key to effective development of many therapeutics. Advanced drug delivery and targeting can offer significant advantages to conventional drugs, such as increased efficiency, convenience, and the potential for line extensions and market expansion. An accessible and easy-to-read textbook, Drug Delivery and Targeting for Pharmacists and Pharmaceutical Scientists is the first book to provide a comprehensive introduction to the principles of advanced drug delivery and targeting, their current applications and potential future developments, including: *Methods to optimize therapeutic efficacy, and the related commercial implications *Difficulties with drug absorption, unwanted distribution and premature inactivation / elimination *Attempts to minimize toxicity or alter immunogenicity *Methods to achieve rate-controlled drug release and effective drug targeting *Novel and established routes of delivery *Use of new generation technologies such as biosensors, microchips, stimuli-sensitive hydrogels and plasmid-based gene therapy This volume is indispensable for pharmaceutical students, scientists and researchers.

Bio-Targets and Drug Delivery Approaches

Sabyasachi Maiti,Kalyan Kumar Sen
Bio Targets and Drug Delivery Approaches Book PDF

Author : Sabyasachi Maiti,Kalyan Kumar Sen
Publisher : CRC Press
Page : 611 pages
File Size : 40,8 Mb
Release : 2016-11-03
Category : Medical
ISBN : 9781498730006

Get Book

Bio-Targets and Drug Delivery Approaches by Sabyasachi Maiti,Kalyan Kumar Sen Pdf

The advances in drug delivery systems over recent years have resulted in a large number of novel delivery systems with the potential to revolutionize the treatment and prevention of diseases. Bio-Targets and Drug Delivery Approaches is an easy-to-read book for students, researchers and pharmaceutical scientists providing a comprehensive introduction to the principles of advanced drug delivery and targeting their current applications and potential future developments.

Submicron Emulsions in Drug Targeting and Delivery

S Benita
Submicron Emulsions in Drug Targeting and Delivery Book PDF

Author : S Benita
Publisher : CRC Press
Page : 353 pages
File Size : 49,9 Mb
Release : 2019-08-16
Category : Medical
ISBN : 9781000717556

Get Book

Submicron Emulsions in Drug Targeting and Delivery by S Benita Pdf

It is anticipated that submicron emulsion and lipid suspension will find numerous and novel medical applications in the near future. The purpose of this multi-authore book is to provide the reader with an up-to-date general overview of submicron emulsions and lipid suspensions (solid lipid nanoparticles) as well as to emphasize the various methods of preparation, characerization, evaluation and potential applications in various therapeutic areas. Leading authors have contributed to this unique book which contains all state of the art and detailed knowledge related to the physico-chemical, pharmaceutical and medical aspects of these most interesting but complex dosage forms, thus making this information easily available to the reader. This book will be of interest to scientists working in the field of drug delivery and targeting in universities as well as in the pharmaceutical, food, cosmetic, veterinary and chemical industries.

Drug Delivery

Monika Schäfer-Korting
Drug Delivery Book PDF

Author : Monika Schäfer-Korting
Publisher : Springer Science & Business Media
Page : 506 pages
File Size : 43,7 Mb
Release : 2010-03-10
Category : Medical
ISBN : 9783642004773

Get Book

Drug Delivery by Monika Schäfer-Korting Pdf

In the view of most experts pharmacology is on drugs, targets, and actions. In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and more aware of the fact that delivery of the active compound to the target site is a key. The present volume gives a topical overview on various modern approaches to drug targeting covering today’s options for specific carrier systems allowing successful drug treatment at various sites of the body difficult to address and allowing to increase the benefit-risk-ratio to the optimum possible.

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

Prashant Kesharwani
Nanotechnology Based Targeted Drug Delivery Systems for Lung Cancer Book PDF

Author : Prashant Kesharwani
Publisher : Academic Press
Page : 340 pages
File Size : 44,6 Mb
Release : 2019-01-26
Category : Business & Economics
ISBN : 9780128163672

Get Book

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer by Prashant Kesharwani Pdf

Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. Provides an overview of an array of nanotechnology-based drug delivery systems Examines the design, synthesis and application of different nanocarriers in drug and gene delivery Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers

Targeted Drug Delivery

Rudolph L. Juliano
Targeted Drug Delivery Book PDF

Author : Rudolph L. Juliano
Publisher : Springer Science & Business Media
Page : 374 pages
File Size : 41,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642758621

Get Book

Targeted Drug Delivery by Rudolph L. Juliano Pdf

The chapters in this volume describe a powerful emerging approach for the therapy of disease. Targeted drug delivery, that is control of the kinetic behavior, tissue distribution, and subcellular localization of pharmaco logically active agents, offers an important means for improving the efficacy of a wide variety of drug therapies. This is particularly true for therapeutic approaches based on newer agents which are the products of recombinant DNA research. These agents, be they peptides, proteins, or oligonucleotides, tend to be larger, more complex, and less stable than traditional drugs. Thus they stand to benefit most from drug delivery systems which can protect them from premature degradation and which can carry them to critical target sites in the body. This volume examines several important aspects of the current state of drug delivery research; it also attempts to project future directions for this field. Successful approaches to drug targeting are based, first of all, on a sophisticated understanding of the biological barriers encountered by the drug-carrier complex as it moves from the portal of administration to the ultimate target site. A second aspect of successful drug delivery is appro priate matching of the disease entity with the pharmacologically active substance and with the delivery system. Thus it is important to be aware of the variety of delivery technologies which currently exist and to be sensitive to their strengths and limitations.

Focal Controlled Drug Delivery

Abraham J. Domb,Wahid Khan
Focal Controlled Drug Delivery Book PDF

Author : Abraham J. Domb,Wahid Khan
Publisher : Springer Science & Business Media
Page : 700 pages
File Size : 44,8 Mb
Release : 2014-02-17
Category : Medical
ISBN : 9781461494348

Get Book

Focal Controlled Drug Delivery by Abraham J. Domb,Wahid Khan Pdf

The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book will review advances in treatment options for diseases localized at a certain tissue or organ.

Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis

Padma V. Devarajan,Prajakta Dandekar,Anisha A. D'Souza
Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis Book PDF

Author : Padma V. Devarajan,Prajakta Dandekar,Anisha A. D'Souza
Publisher : Springer Nature
Page : 560 pages
File Size : 55,9 Mb
Release : 2019-11-09
Category : Medical
ISBN : 9783030291686

Get Book

Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis by Padma V. Devarajan,Prajakta Dandekar,Anisha A. D'Souza Pdf

This book elaborates on drug delivery targeting via intracellular delivery, specifically through the Receptor Mediated Endocytosis (RME) approach, due to the involvement of cellular receptors in various grave diseases. Targeted delivery relies on two basic approaches, passive and active targeting. While passive targeting approaches have shown great promise, the improved selectivity achieved with active targeting approaches has resulted in significantly higher efficacy. Interestingly there are numerous strategies for active targeting, many of which are already highlighted in , Targeted Drug Delivery: Concepts and Applications. Nevertheless an exciting and practical strategy for active targeting, which could enable high intracellular delivery, is through exploitation of RME. Cells in the body express receptors to enable various physiological and biochemical processes. As a result, many of these receptors are overexpressed in pathological conditions, or newer receptors expressed due to defective cellular functioning. RME is based on exploitation of such receptors to achieve intracellular delivery. While targeted delivery can have manifold applications, in this book we focus on two major and challenging therapeutic areas; i) Cancer and ii) Infectious Diseases. Targeted Intracellular Drug Delivery by Receptor Medicated Endocytosis discusses the major receptors that are useful for targeted delivery for these afflictions. A major section of this book is dedicated to details regarding their occurrence and location, the recognition domain of the receptor, structure activity relationship of substrate /ligand for selective binding, ligands explored, antagonists for ligand binding and relevance of these aspects for therapy of cancer and infectious diseases. These facets are elucidated with the help of specific examples from academic research and also emphasize commercial products, wherever relevant. In vitro cellular models relied on for assessing receptor mediated cellular targeting and in vivo models depicting clinical efficacy are focused on in a separate section. Finally, we briefly discuss the regulatory and toxicity issues that may be associated specifically with the RME approach of intracellular drug delivery.

Liposomes in Drug Delivery

AlexanderT. Florence
Liposomes in Drug Delivery Book PDF

Author : AlexanderT. Florence
Publisher : Routledge
Page : 302 pages
File Size : 51,9 Mb
Release : 2017-10-05
Category : Medical
ISBN : 9781351435048

Get Book

Liposomes in Drug Delivery by AlexanderT. Florence Pdf

First Published in 2017. Routledge is an imprint of Taylor & Francis, an Informa company.

Brain Targeted Drug Delivery Systems

Huile Gao,Xiaoling Gao
Brain Targeted Drug Delivery Systems Book PDF

Author : Huile Gao,Xiaoling Gao
Publisher : Academic Press
Page : 499 pages
File Size : 49,9 Mb
Release : 2018-09-20
Category : Medical
ISBN : 9780128140024

Get Book

Brain Targeted Drug Delivery Systems by Huile Gao,Xiaoling Gao Pdf

Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain. Provides an overview of brain targeting drug delivery that is useful to both academic and industry-based researchers Discusses key points in developing brain targeting drug delivery systems Summarizes and presents currently available strategies for brain targeting drug delivery Covers not only current studies and their strengths, but also gives insight into the pitfalls of current research