Drug Delivery And Targeting

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Targeted Drug Delivery : Concepts and Design

Padma V. Devarajan,Sanyog Jain
Targeted Drug Delivery Concepts and Design Book PDF

Author : Padma V. Devarajan,Sanyog Jain
Publisher : Springer
Page : 788 pages
File Size : 55,8 Mb
Release : 2014-12-08
Category : Medical
ISBN : 9783319113555

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Targeted Drug Delivery : Concepts and Design by Padma V. Devarajan,Sanyog Jain Pdf

This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.

Drug Delivery and Targeting

Anya M. Hillery,Andrew W. Lloyd,James Swarbrick
Drug Delivery and Targeting Book PDF

Author : Anya M. Hillery,Andrew W. Lloyd,James Swarbrick
Publisher : CRC Press
Page : 448 pages
File Size : 49,6 Mb
Release : 2003-09-02
Category : Medical
ISBN : 9780203302767

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Drug Delivery and Targeting by Anya M. Hillery,Andrew W. Lloyd,James Swarbrick Pdf

The advances in biotechnology and molecular biology over recent years have resulted in a large number of novel molecules with the potential to revolutionize the treatment and prevention of disease. However, such potential is severely compromised by significant obstacles to delivery of these drugs in vivo. These obstacles are often so great that effective drug delivery and targeting is now recognized as the key to effective development of many therapeutics. Advanced drug delivery and targeting can offer significant advantages to conventional drugs, such as increased efficiency, convenience, and the potential for line extensions and market expansion. An accessible and easy-to-read textbook, Drug Delivery and Targeting for Pharmacists and Pharmaceutical Scientists is the first book to provide a comprehensive introduction to the principles of advanced drug delivery and targeting, their current applications and potential future developments, including: *Methods to optimize therapeutic efficacy, and the related commercial implications *Difficulties with drug absorption, unwanted distribution and premature inactivation / elimination *Attempts to minimize toxicity or alter immunogenicity *Methods to achieve rate-controlled drug release and effective drug targeting *Novel and established routes of delivery *Use of new generation technologies such as biosensors, microchips, stimuli-sensitive hydrogels and plasmid-based gene therapy This volume is indispensable for pharmaceutical students, scientists and researchers.

Targeted Drug Delivery

Rachael W. Sirianni,Bahareh Behkam
Targeted Drug Delivery Book PDF

Author : Rachael W. Sirianni,Bahareh Behkam
Publisher : Humana Press
Page : 230 pages
File Size : 51,5 Mb
Release : 2018-07-27
Category : Medical
ISBN : 1493986597

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Targeted Drug Delivery by Rachael W. Sirianni,Bahareh Behkam Pdf

This volume looks at the latest techniques used to enable therapeutic molecules to be targeted for site-specific delivery. The chapters in this book discuss topics such as approaches to express biologically derived and synthetic nanocarriers; strategies to assist in nanocarrier targeting to specific cells and tissues; and methods for evaluating delivery and efficiency for new classes of agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Targeted Drug Delivery: Methods and Protocols is a valuable resource for anyone interested in understanding the diversity of methods used in this evolving field.

Drug Targeting and Stimuli Sensitive Drug Delivery Systems

Alexandru Mihai Grumezescu
Drug Targeting and Stimuli Sensitive Drug Delivery Systems Book PDF

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 836 pages
File Size : 41,7 Mb
Release : 2018-05-21
Category : Science
ISBN : 9780128136904

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Drug Targeting and Stimuli Sensitive Drug Delivery Systems by Alexandru Mihai Grumezescu Pdf

Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective drug delivery systems. Shows how the use of nanomaterials can help target a drug to specific tissues and cells Explores the development of stimuli-responsive drug delivery systems Includes case studies to showcase how stimuli responsive nanosystems are used in a variety of therapies, including camptothecin delivery, diabetes and cancer therapy

FASTtrack Pharmaceutics

Yvonne Perrie,Thomas Rades
FASTtrack Pharmaceutics Book PDF

Author : Yvonne Perrie,Thomas Rades
Publisher : Pharmaceutical Press
Page : 257 pages
File Size : 47,5 Mb
Release : 2012
Category : Medical
ISBN : 9780857110596

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FASTtrack Pharmaceutics by Yvonne Perrie,Thomas Rades Pdf

"Pharmaceutics - Drug delivery and targeting focuses on what pharmacy students really need to know in order to pass exams, providing concise, bulleted information, key points, tips and an all-important self-assessment section which includes MCQs."--Page 4 of cover.

Drug Delivery

Anya M Hillery,Kinam Park
Drug Delivery Book PDF

Author : Anya M Hillery,Kinam Park
Publisher : CRC Press
Page : 634 pages
File Size : 43,6 Mb
Release : 2016-09-15
Category : Medical
ISBN : 9781482217742

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Drug Delivery by Anya M Hillery,Kinam Park Pdf

This book provides a comprehensive introduction to advanced drug delivery and targeting, covering their principles, current applications, and potential future developments. This edition has been updated to reflect significant trends and cutting-edge advances that have occurred since the first edition was published. All the original chapters have been retained, but the material therein has been updated. Eight new chapters have been added that deal with entirely new technologies and approaches. Features: Offers a comprehensive introduction to the fundamental concepts and underlying scientific principles of drug delivery and targeting Presents an in-depth analysis of the opportunities and obstacles afforded by the application of nanotechnologies for drug delivery and targeting Includes a revised and expanded section on the major epithelial routes of drug delivery currently under investigation Describes the most recent, emerging, and innovative technologies of drug delivery Provides real-life examples of the clinical translation of drug delivery technologies through the use of case studies Discusses the pertinent regulatory hurdles and safety issues of drug delivery and targeting systems—crucial considerations in order to achieve licensing approval for these new technologies

Bio-Targets and Drug Delivery Approaches

Sabyasachi Maiti,Kalyan Kumar Sen
Bio Targets and Drug Delivery Approaches Book PDF

Author : Sabyasachi Maiti,Kalyan Kumar Sen
Publisher : CRC Press
Page : 611 pages
File Size : 52,5 Mb
Release : 2016-11-03
Category : Medical
ISBN : 9781498730006

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Bio-Targets and Drug Delivery Approaches by Sabyasachi Maiti,Kalyan Kumar Sen Pdf

The advances in drug delivery systems over recent years have resulted in a large number of novel delivery systems with the potential to revolutionize the treatment and prevention of diseases. Bio-Targets and Drug Delivery Approaches is an easy-to-read book for students, researchers and pharmaceutical scientists providing a comprehensive introduction to the principles of advanced drug delivery and targeting their current applications and potential future developments.

Drug Delivery with Targeted Nanoparticles

Yılmaz Çapan,Adem Sahin,Hayrettin Tonbul
Drug Delivery with Targeted Nanoparticles Book PDF

Author : Yılmaz Çapan,Adem Sahin,Hayrettin Tonbul
Publisher : CRC Press
Page : 654 pages
File Size : 45,6 Mb
Release : 2021-11-30
Category : Medical
ISBN : 9781000375305

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Drug Delivery with Targeted Nanoparticles by Yılmaz Çapan,Adem Sahin,Hayrettin Tonbul Pdf

Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared with conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires several evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.

Targeted Delivery of Small and Macromolecular Drugs

Ajit S. Narang,Ram I. Mahato
Targeted Delivery of Small and Macromolecular Drugs Book PDF

Author : Ajit S. Narang,Ram I. Mahato
Publisher : CRC Press
Page : 630 pages
File Size : 55,6 Mb
Release : 2010-05-12
Category : Medical
ISBN : 9781420087734

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Targeted Delivery of Small and Macromolecular Drugs by Ajit S. Narang,Ram I. Mahato Pdf

Site-specific drug delivery and targeting attracts much research interest from both academia and industry, but because of the many challenges faced in the development of these systems, only a handful of targeted therapies have successfully made it into clinical practice. Focusing on the delivery technologies that utilize both systemic and local rou

Drug Delivery

Monika Schäfer-Korting
Drug Delivery Book PDF

Author : Monika Schäfer-Korting
Publisher : Springer Science & Business Media
Page : 506 pages
File Size : 50,6 Mb
Release : 2010-03-10
Category : Medical
ISBN : 9783642004773

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Drug Delivery by Monika Schäfer-Korting Pdf

In the view of most experts pharmacology is on drugs, targets, and actions. In the context the drug as a rule is seen as an active pharmaceutical ingredient and not as a complex mixture of chemical entities of a well defined structure. Today, we are becoming more and more aware of the fact that delivery of the active compound to the target site is a key. The present volume gives a topical overview on various modern approaches to drug targeting covering today’s options for specific carrier systems allowing successful drug treatment at various sites of the body difficult to address and allowing to increase the benefit-risk-ratio to the optimum possible.

Smart Drug Delivery System

Ali Demir Sezer
Smart Drug Delivery System Book PDF

Author : Ali Demir Sezer
Publisher : BoD – Books on Demand
Page : 400 pages
File Size : 49,5 Mb
Release : 2016-02-10
Category : Medical
ISBN : 9789535122470

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Smart Drug Delivery System by Ali Demir Sezer Pdf

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Multifunctional Nanoparticles for Drug Delivery Applications

Sonke Svenson,Robert K. Prud'homme
Multifunctional Nanoparticles for Drug Delivery Applications Book PDF

Author : Sonke Svenson,Robert K. Prud'homme
Publisher : Springer Science & Business Media
Page : 371 pages
File Size : 45,6 Mb
Release : 2012-02-22
Category : Technology & Engineering
ISBN : 9781461423058

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Multifunctional Nanoparticles for Drug Delivery Applications by Sonke Svenson,Robert K. Prud'homme Pdf

This book clearly demonstrates the progression of nanoparticle therapeutics from basic research to applications. This book, unlike others covering nanoparticles used in medical applications, presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy.

Submicron Emulsions in Drug Targeting and Delivery

S Benita
Submicron Emulsions in Drug Targeting and Delivery Book PDF

Author : S Benita
Publisher : CRC Press
Page : 353 pages
File Size : 41,6 Mb
Release : 2019-08-16
Category : Medical
ISBN : 9781000717556

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Submicron Emulsions in Drug Targeting and Delivery by S Benita Pdf

It is anticipated that submicron emulsion and lipid suspension will find numerous and novel medical applications in the near future. The purpose of this multi-authore book is to provide the reader with an up-to-date general overview of submicron emulsions and lipid suspensions (solid lipid nanoparticles) as well as to emphasize the various methods of preparation, characerization, evaluation and potential applications in various therapeutic areas. Leading authors have contributed to this unique book which contains all state of the art and detailed knowledge related to the physico-chemical, pharmaceutical and medical aspects of these most interesting but complex dosage forms, thus making this information easily available to the reader. This book will be of interest to scientists working in the field of drug delivery and targeting in universities as well as in the pharmaceutical, food, cosmetic, veterinary and chemical industries.

Surface Modification of Nanoparticles for Targeted Drug Delivery

Yashwant V Pathak
Surface Modification of Nanoparticles for Targeted Drug Delivery Book PDF

Author : Yashwant V Pathak
Publisher : Springer
Page : 499 pages
File Size : 54,8 Mb
Release : 2019-03-11
Category : Medical
ISBN : 9783030061159

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Surface Modification of Nanoparticles for Targeted Drug Delivery by Yashwant V Pathak Pdf

This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

Brain Targeted Drug Delivery Systems

Huile Gao,Xiaoling Gao
Brain Targeted Drug Delivery Systems Book PDF

Author : Huile Gao,Xiaoling Gao
Publisher : Academic Press
Page : 499 pages
File Size : 46,5 Mb
Release : 2018-09-20
Category : Medical
ISBN : 9780128140024

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Brain Targeted Drug Delivery Systems by Huile Gao,Xiaoling Gao Pdf

Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain. Provides an overview of brain targeting drug delivery that is useful to both academic and industry-based researchers Discusses key points in developing brain targeting drug delivery systems Summarizes and presents currently available strategies for brain targeting drug delivery Covers not only current studies and their strengths, but also gives insight into the pitfalls of current research