Désiré Collen Biotech Pioneer

Author : Paul Huybrechts,Frieda Van Wijck
Publisher : Désiré Collen
Page : 290 pages
File Size : 45,8 Mb
Release : 2020-08-27
Category : Biography & Autobiography
ISBN : 9781649996084

Get Book

Désiré Collen - Biotech Pioneer by Paul Huybrechts,Frieda Van Wijck Pdf

Désiré Collen, Biotech Pioneer relates the fascinating story of scientific discovery in a time when biotechnology was not yet a science. Although the cultivation and cross fertilization of plants were, strictly speaking, biotechnological techniques, modern biotechnology dates from the early 1970s, when pioneers such as biochemist Herbert Boyer from the university of California managed to transfer genetic material into a bacterium. Together with venture capitalist Robert Swanson, Boyer set up Genentech, one of the first genetic engineering companies. Just a few years later, on the other side of the Atlantic, in Leuven, Désiré Collen discovered t-PA, the enzyme responsible for fibrinolysis, or the dissolving of blood clots. Clogged arteries were then still one of the major causes of death. The ensuing cooperation between Collen and Genentech was the beginning of a long-lasting success story, from which not only Collen but also scientific research and the University of Leuven benefitted greatly for many years. According to a Reuters ranking, KU Leuven has been, from 2016 onwards, the most innovative university in Europe. Flanders and Belgium served as the cradle of several highly successful biotech companies. t-PA was a relatively expensive medicine, and Collen went on to develop a much cheaper clot-dissolving remedy to benefit patients in less affluent countries. He failed, however, to find the necessary finances for Phase 3 trials. Meanwhile, he had set up ThromboGenics, a company which later specialized in ophthalmology. Collen continued to stimulate and finance research in other fields, such as the cardiovascular research of Peter Carmeliet. In 2013 he left ThromboGenics, following a difference in views on the company’s focus, and in 2015 he set up Fund+, a biotech-oriented investment firm. Fund+ has meanwhile acquired a prominent place among European biotech investment funds and has scored some astonishing early successes. In June 2020, Fund+ had 13 companies in its portfolio, with several more waiting to come on board.

Author : Oliver Uecke,Robin De Cock,Thomas Crispeels,Bart Clarysse
Publisher : World Scientific
Page : 292 pages
File Size : 41,7 Mb
Release : 2015-01-06
Category : Technology & Engineering
ISBN : 9781783266821

Get Book

Effective Technology Transfer in Biotechnology by Oliver Uecke,Robin De Cock,Thomas Crispeels,Bart Clarysse Pdf

Biotechnology is referred to as one of the key enabling technologies of the 21st century. It has the potential to offer solutions for a number of health and resource-based problems the world is facing, such as unmet medical needs and fossil fuel dependency. Considerable effort and investment has been expended in recent years to try and improve the outcomes of technology transfer in order to fulfill this potential. This book presents seventeen best-practice case studies on the topic of effective technology transfer in biotechnology. The selected case studies focus on technology transfer offices, funding models, incubators, education and clusters. Each presents an overview of an initiative that was deployed in Europe with the aim of supporting and stimulating the transfer of biotechnology discoveries and technologies from research laboratories to society. Readers are provided with a critical assessment of each initiative and policy makers, entrepreneurs, cluster managers and research institute managers will find inspiring lessons they can draw on when developing and implementing similar initiatives elsewhere. These cases are the product of research undertaken as part of the ETTBio (Effective Technology Transfer in Biotechnology) project, co-financed by the European Union (ERDF — European Regional Development Fund) and made possible by the INTERREG IVC Programme. ETTBio commenced in January 2012 and concluded in December 2014. Contents:Technology Transfer Office (TTO):Case Study 1: A Look Inside Imperial College's TTOCase Study 2: Technology Transfer at VIBCase Study 3: The Creation of a New Technology Transfer OfficeCase Study 4: A Model for IP Transfer and Shareholding for University Spin-Offs: The "Dresden Model"Funding:Case Study 5: Environmental Success Factors of Imperial College's TTOCase Study 6: The Industrial Research FundCase Study 7: Regional Innovation Vouchers as an Effective Tool for Supporting Technology TransferCase Study 8: Public Funds for Patenting, Valorization and Science-Industry CollaborationIncubators:Case Study 9: The Imperial BioincubatorCase Study 10: Idea Lab — A Platform for Students to Develop New IdeasEducation:Case Study 11: Entrepreneurship and Technology Transfer Education at the Vrije Universiteit BrusselCase Study 12: BioEmprenedor XXI: Guidance Program for Starting Up and Growing Companies in the Life Sciences ArenaCase Study 13: Education for ScientistsClusters:Case Study 14: The Biocat Model: Managing the Bioregion of CataloniaCase Study 15: The Effects of a Cluster on a Spin-Off — The Foundation of AblynxCase Study 16: Brokerage Event: Matching International R&D projectsCase Study 17: The DRESDEN-concept: A Focus on Shared Services and Facilities Readership: Policy makers, entrepreneurs, cluster managers and research institute managers in biotechnology. Key Features:Focuses on effective technology transfer in the European contextTechnology specific focus on biotechnologyIdentifies and provides a detailed examination of best practice case studies in technology transfer across Europe. These include both highly experienced regions such as London and Flanders as well as "newcomers" such as Poland and EstoniaKeywords:Technology Transfer;Biotechnology;Effectiveness;Efficiency;Commercialization;Research;Funding;Cluster;Education;Technology Transfer Offices;Incubation

Author : P. Buckel
Publisher : Springer Science & Business Media
Page : 226 pages
File Size : 52,8 Mb
Release : 2001-08-01
Category : Medical
ISBN : 3764359048

Get Book

Recombinant Protein Drugs by P. Buckel Pdf

Recombinant protein drugs are intimately associated with the impressive success story of the Biotech Industry during the past thirty years, some of them belonging to the most successful pharmaceutical products. More than thirty different proteins are available for a variety of clinical applications, over 300 proteins are presently being evaluated in clinical trials. In this new volume of the MDT series, historical, technical and clinical aspects of recombinant protein drug discovery and development are presented, covering past, present and future highlights. Leading scientists and co-founders of early Biotech companies describe technical breakthroughs and the fascinating story of pioneering discoveries, as well as the long way of translating them into products and business. Therefore, this book represents an exciting documentation of the beginning of a new era in the pharmaceutical industry. In addition, scientists from basic research, clinic and industry actively involved in new developments discuss...

Author : Anonim
Publisher : Unknown
Page : 250 pages
File Size : 47,6 Mb
Release : 1999
Category : Flanders (Belgium)
ISBN : UCBK:C072558717

Get Book

Flanders by Anonim Pdf

Author : Claude E. Barfield,John E. Calfee
Publisher : A E I Press
Page : 116 pages
File Size : 42,5 Mb
Release : 2007
Category : Law
ISBN : 0844742562

Get Book

Biotechnology and the Patent System by Claude E. Barfield,John E. Calfee Pdf

American patent law has reached an unprecedented crossroads, prodded by a landmark Supreme Court decision this spring and the prospect of sweeping new federal legislation this fall. At this critical time, Biotechnology and the Patent System: Balancing Innovation and Property Rights provides a timely look at the complex issues involved in making patent law for cutting-edge high-tech industries such as the biotechnology and computer software sectors.

Author : Eric Schlosser
Publisher : Houghton Mifflin Harcourt
Page : 387 pages
File Size : 42,6 Mb
Release : 2012
Category : Business & Economics
ISBN : 9780547750330

Get Book

Fast Food Nation by Eric Schlosser Pdf

An exploration of the fast food industry in the United States, from its roots to its long-term consequences.

Author : R. W. Connell,Raewyn Connell
Publisher : Polity
Page : 351 pages
File Size : 52,7 Mb
Release : 2005
Category : Social Science
ISBN : 9780745634265

Get Book

Masculinities by R. W. Connell,Raewyn Connell Pdf

This is an exciting new edition of R.W. Connell's ground-breaking text, which has become a classic work on the nature and construction of masculine identity. Connell argues that there is not one masculinity, but many different masculinities, each associated with different positions of power. In a world gender order that continues to privilege men over women, but also raises difficult issues for men and boys, his account is more pertinent than ever before. In a substantial new introduction and conclusion, Connell discusses the development of masculinity studies in the ten years since the book's initial publication. He explores global gender relations, new theories, and practical uses of mascunlinity research. Looking to the future, his new concluding chapter addresses the politics of masculinities, and the implications of masculinity research for understanding current world issues. Against the backdrop of an increasingly divided world, dominated by neo-conservative politics, Connell's account highlights a series of compelling questions about the future of human society. This second edition of Connell's classic book will be essential reading for students taking courses on masculinities and gender studies, and will be of interest to students and scholars across the humanities and social sciences.

Author : J. Michael BISHOP
Publisher : Harvard University Press
Page : 288 pages
File Size : 53,8 Mb
Release : 2009-06-30
Category : Science
ISBN : 9780674020979

Get Book

How to Win the Nobel Prize by J. Michael BISHOP Pdf

In 1989 Michael Bishop and Harold Varmus were awarded the Nobel Prize for their discovery that normal genes under certain conditions can cause cancer. In this book, Bishop tells us how he and Varmus made their momentous discovery. More than a lively account of the making of a brilliant scientist, How to Win the Nobel Prize is also a broader narrative combining two major and intertwined strands of medical history: the long and ongoing struggles to control infectious diseases and to find and attack the causes of cancer. Alongside his own story, that of a youthful humanist evolving into an ambivalent medical student, an accidental microbiologist, and finally a world-class researcher, Bishop gives us a fast-paced and engrossing tale of the microbe hunters. It is a narrative enlivened by vivid anecdotes about our deadliest microbial enemies--the Black Death, cholera, syphilis, tuberculosis, malaria, smallpox, HIV--and by biographical sketches of the scientists who led the fight against these scourges. Bishop then provides an introduction for nonscientists to the molecular underpinnings of cancer and concludes with an analysis of many of today's most important science-related controversies--ranging from stem cell research to the attack on evolution to scientific misconduct. How to Win the Nobel Prize affords us the pleasure of hearing about science from a brilliant practitioner who is a humanist at heart. Bishop's perspective will be valued by anyone interested in biomedical research and in the past, present, and future of the battle against cancer. Table of Contents: List of Illustrations Preface 1. The Phone Call 2. Accidental Scientist 3. People and Pestilence 4. Opening the Black Box of Cancer 5. Paradoxical Strife Notes Credits Index Reviews of this book: Despite his book's encouraging title, Bishop--who won a Nobel Prize in Physiology and Medicine in 1989--cautions that "I have not written an instruction manual for pursuit of the prize." Instead, he has written an amiable reflection on the experience of being a Nobelist, intertwined with some history and anecdotes about the award, and balanced by a wide-ranging review of his own career as an "accidental scientist"...Along the way, Bishop reflects on the history of our knowledge of microbes, cancer, the politics of funding research and present-day disenchantment with science. His main purpose in writing this book, Bishop says, is to show that "scientists are supremely human"--which he does with grace and charm. --Publishers Weekly Reviews of this book: How to Win the Nobel Prize is typical Bishop: modest, funny, insightful and offering an extremely clear and brief explanation of the basic scientific achievement that won the 1989 Nobel Prize in physiology or medicine for himself and longtime colleague, Harold Varmus, now president of the Memorial Sloan-Kettering Cancer Center. --David Perlman, San Francisco Chronicle Reviews of this book: In these pages Bishop reveals himself as a good writer blessed with enviable clarity, someone sensible and levelheaded who likes people and is enamored of his science. --John Tyler Bonner, New York Times Book Review Reviews of this book: This is a treasure...Above all, How to Win the Nobel Prize is a civilised book and a lavishly rewarding one. --Roy Herbert, New Scientist Reviews of this book: At its heart this analysis of science and the scientific world is a jewel. How to Win the Nobel Prize is an inspirational book, full of careful analysis and judgement. --John Oxford, Times Higher Education Supplement Reviews of this book: Bishop is a gifted communicator and teacher, and he sets about his task of educating scientists and the public by describing his career in science and science politics...In the end, Bishop's book provides a road map for scientists and the public to build a robust scientific community that serves our society well. --Andreas Trumpp and Daniel Kalman, Nature Cell Biology J. Michael Bishop has written his book 'to show that scientists are supremely human.' The book is also a lucid explanation of how science has been harnessed to fight the human afflictions of cancer and infectious disease. And the story ends with a wide-ranging overview of today's challenges to the scientific enterprise. Overall, a must-read for all those interested in science and scientists--even those with absolutely no interest in winning a Nobel Prize! --Bruce Alberts, President, National Academy of Sciences J. Michael Bishop is that rare scientist who is widely read in literature and poetry. Most importantly, he remembers what he reads and thinks deeply about it, as well as about all else in his rich life. The Nobel Prize he won and richly deserved, his political activism, his understanding of cancer and microbiology, his devotion to the practice of science--all these provide fodder for his writerly craft. Quite a wonderful book! --David Baltimore, Nobel Laureate and President, California Institute of Technology

Author : Kathryn J. Hannah,Marion J. Ball,Margaret J.A. Edwards
Publisher : Springer Science & Business Media
Page : 311 pages
File Size : 45,9 Mb
Release : 2013-04-17
Category : Medical
ISBN : 9781475722468

Get Book

Introduction to Nursing Informatics by Kathryn J. Hannah,Marion J. Ball,Margaret J.A. Edwards Pdf

This series is intended for the rapidly increasing number of health care professionals who have rudimentary knowledge and experience in health care computing and are seeking opportunities to expand their horizons. It does not attempt to compete with the primers already on the market. Eminent international experts will edit, author, or contribute to each volume in order to provide comprehensive and current accounts of in novations and future trends in this quickly evolving field. Each book will be practical, easy to use, and weIl referenced. Our aim is for the series to encompass all of the health professions by focusing on specific professions, such as nursing, in individual volumes. However, integrated computing systems are only one tool for improving communication among members of the health care team. Therefore, it is our hope that the series will stimulate professionals to explore additional me ans of fostering interdisciplinary exchange. This se ries springs from a professional collaboration that has grown over the years into a highly valued personal friendship. Our joint values put people first. If the Computers in Health Care series lets us share those values by helping health care professionals to communicate their ideas for the benefit of patients, then our efforts will have succeeded.

Author : Anna Lowenhaupt Tsing,Nils Bubandt,Elaine Gan,Heather Anne Swanson
Publisher : U of Minnesota Press
Page : 709 pages
File Size : 40,6 Mb
Release : 2017-05-30
Category : Science
ISBN : 9781452954493

Get Book

Arts of Living on a Damaged Planet by Anna Lowenhaupt Tsing,Nils Bubandt,Elaine Gan,Heather Anne Swanson Pdf

Living on a damaged planet challenges who we are and where we live. This timely anthology calls on twenty eminent humanists and scientists to revitalize curiosity, observation, and transdisciplinary conversation about life on earth. As human-induced environmental change threatens multispecies livability, Arts of Living on a Damaged Planet puts forward a bold proposal: entangled histories, situated narratives, and thick descriptions offer urgent “arts of living.” Included are essays by scholars in anthropology, ecology, science studies, art, literature, and bioinformatics who posit critical and creative tools for collaborative survival in a more-than-human Anthropocene. The essays are organized around two key figures that also serve as the publication’s two openings: Ghosts, or landscapes haunted by the violences of modernity; and Monsters, or interspecies and intraspecies sociality. Ghosts and Monsters are tentacular, windy, and arboreal arts that invite readers to encounter ants, lichen, rocks, electrons, flying foxes, salmon, chestnut trees, mud volcanoes, border zones, graves, radioactive waste—in short, the wonders and terrors of an unintended epoch. Contributors: Karen Barad, U of California, Santa Cruz; Kate Brown, U of Maryland, Baltimore; Carla Freccero, U of California, Santa Cruz; Peter Funch, Aarhus U; Scott F. Gilbert, Swarthmore College; Deborah M. Gordon, Stanford U; Donna J. Haraway, U of California, Santa Cruz; Andreas Hejnol, U of Bergen, Norway; Ursula K. Le Guin; Marianne Elisabeth Lien, U of Oslo; Andrew Mathews, U of California, Santa Cruz; Margaret McFall-Ngai, U of Hawaii, Manoa; Ingrid M. Parker, U of California, Santa Cruz; Mary Louise Pratt, NYU; Anne Pringle, U of Wisconsin, Madison; Deborah Bird Rose, U of New South Wales, Sydney; Dorion Sagan; Lesley Stern, U of California, San Diego; Jens-Christian Svenning, Aarhus U.

Author : Hans de Kroon,Eric J.W. Visser
Publisher : Springer Science & Business Media
Page : 424 pages
File Size : 46,5 Mb
Release : 2003-05-21
Category : Science
ISBN : 3540001859

Get Book

Root Ecology by Hans de Kroon,Eric J.W. Visser Pdf

In the course of evolution, a great variety of root systems have learned to overcome the many physical, biochemical and biological problems brought about by soil. This development has made them a fascinating object of scientific study. This volume gives an overview of how roots have adapted to the soil environment and which roles they play in the soil ecosystem. The text describes the form and function of roots, their temporal and spatial distribution, and their turnover rate in various ecosystems. Subsequently, a physiological background is provided for basic functions, such as carbon acquisition, water and solute movement, and for their responses to three major abiotic stresses, i.e. hard soil structure, drought and flooding. The volume concludes with the interactions of roots with other organisms of the complex soil ecosystem, including symbiosis, competition, and the function of roots as a food source.

Author : Linda K. Trevino,Katherine A. Nelson
Publisher : John Wiley & Sons
Page : 491 pages
File Size : 48,9 Mb
Release : 2016-09-13
Category : Business & Economics
ISBN : 9781119194309

Get Book

Managing Business Ethics by Linda K. Trevino,Katherine A. Nelson Pdf

Revised edition of the authors' Managing business ethics, [2014]

Author : Toss Gascoigne,Bernard Schiele,Joan Leach,Michelle Riedlinger,Luisa Massarani,Bruce V. Lewenstein,Peter Broks
Publisher : ANU Press
Page : 994 pages
File Size : 43,8 Mb
Release : 2020-09-14
Category : Science
ISBN : 9781760463663

Get Book

Communicating Science by Toss Gascoigne,Bernard Schiele,Joan Leach,Michelle Riedlinger,Luisa Massarani,Bruce V. Lewenstein,Peter Broks Pdf

Modern science communication has emerged in the twentieth century as a field of study, a body of practice and a profession—and it is a practice with deep historical roots. We have seen the birth of interactive science centres, the first university actions in teaching and conducting research, and a sharp growth in employment of science communicators. This collection charts the emergence of modern science communication across the world. This is the first volume to map investment around the globe in science centres, university courses and research, publications and conferences as well as tell the national stories of science communication. How did it all begin? How has development varied from one country to another? What motivated governments, institutions and people to see science communication as an answer to questions of the social place of science? Communicating Science describes the pathways followed by 39 different countries. All continents and many cultures are represented. For some countries, this is the first time that their science communication story has been told.

Author : Darcy H. Shaw,Sherri L. Ihle
Publisher : John Wiley & Sons
Page : 753 pages
File Size : 51,8 Mb
Release : 2013-05-30
Category : Medical
ISBN : 9781118708972

Get Book

Small Animal Internal Medicine by Darcy H. Shaw,Sherri L. Ihle Pdf

Review in concise, outline format for veterinary students preparing for National Boards. Includes exam-style review questions.

Author : Patricia Freitag Ericsson,Richard Haswell
Publisher : Unknown
Page : 284 pages
File Size : 52,9 Mb
Release : 2006-03-15
Category : Education
ISBN : UOM:39015062538106

Get Book

Machine Scoring of Student Essays by Patricia Freitag Ericsson,Richard Haswell Pdf

The current trend toward machine-scoring of student work, Ericsson and Haswell argue, has created an emerging issue with implications for higher education across the disciplines, but with particular importance for those in English departments and in administration. The academic community has been silent on the issue—some would say excluded from it—while the commercial entities who develop essay-scoring software have been very active. Machine Scoring of Student Essays is the first volume to seriously consider the educational mechanisms and consequences of this trend, and it offers important discussions from some of the leading scholars in writing assessment. Reading and evaluating student writing is a time-consuming process, yet it is a vital part of both student placement and coursework at post-secondary institutions. In recent years, commercial computer-evaluation programs have been developed to score student essays in both of these contexts. Two-year colleges have been especially drawn to these programs, but four-year institutions are moving to them as well, because of the cost-savings they promise. Unfortunately, to a large extent, the programs have been written, and institutions are installing them, without attention to their instructional validity or adequacy. Since the education software companies are moving so rapidly into what they perceive as a promising new market, a wider discussion of machine-scoring is vital if scholars hope to influence development and/or implementation of the programs being created. What is needed, then, is a critical resource to help teachers and administrators evaluate programs they might be considering, and to more fully envision the instructional consequences of adopting them. And this is the resource that Ericsson and Haswell are providing here.