Early Life Origins Of Ageing And Longevity

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Early Life Origins of Ageing and Longevity

Alexander Vaiserman
Early Life Origins of Ageing and Longevity Book PDF

Author : Alexander Vaiserman
Publisher : Springer
Page : 310 pages
File Size : 47,5 Mb
Release : 2019-07-29
Category : Science
ISBN : 9783030249588

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Early Life Origins of Ageing and Longevity by Alexander Vaiserman Pdf

This book provides a comprehensive overview of the field of developmental programming of ageing phenotypes. Although gerontological research has traditionally focused on later stages of the life cycle, growing evidence indicates that both the rate of ageing-associated functional declines, and the risks of later-life chronic pathological conditions, can be traced to origins early in life. While other books in the field concentrate on the developmental origin of particular disorders, this volume offers a detailed guide to all important aspects of the role of early-life conditions in programming both chronic pathological conditions and the ageing process. Interest in the study of ageing and longevity had its beginnings in research on the fetal origins of adult disease. This has evolved into a hypothesis on the Developmental Origins of Adult Health and Disease (DOHaD), which postulates that adverse environmental exposures during critical in-utero and early postnatal stages of development may permanently change physiological responses and cause functional impairments and disorders in adult life. In this book, the contributing authors and leading experts from around the world, describe research on mechanisms underlying the developmental programming phenomenon, as well as interventional strategies aimed at restoring developmentally disrupted epigenetic patterns. Early Life Origins of Ageing and Longevity benefits a wide audience of working scientists, clinicians, and advanced students, and will also interest scientifically curious general readers who wish to know more about current research in this rapidly evolving field.

Ageing: A Very Short Introduction

Nancy A. Pachana
Ageing A Very Short Introduction Book PDF

Author : Nancy A. Pachana
Publisher : Oxford University Press
Page : 144 pages
File Size : 42,6 Mb
Release : 2016-11-17
Category : Psychology
ISBN : 9780191038464

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Ageing: A Very Short Introduction by Nancy A. Pachana Pdf

Ageing is an activity we are familiar with from an early age. In our younger years upcoming birthdays are anticipated with an excitement that somewhat diminishes as the years progress. As we grow older we are bombarded with advice on ways to overcome, thwart, resist, and, on the rare occasion, embrace, one's ageing. Have all human beings from the various historical epochs and cultures viewed aging with this same ambivalence? In this Very Short Introduction Nancy A. Pachana discusses the lifelong dynamic changes in biological, psychological, and social functioning involved in ageing. Increased lifespans in the developed and the developing world have created an urgent need to find ways to enhance our functioning and well-being in the later decades of life, and this need is reflected in policies and action plans addressing our ageing populations from the World Health Organization and the United Nations. Looking to the future, Pachana considers advancements in the provision for our ageing populations, including revolutionary models of nursing home care such as Green House nursing homes in the USA and Small Group Living homes in the Netherlands. She shows that understanding the process of ageing is not only important for individuals, but also for societies and nations, if the full potential of those entering later life is to be realised. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Early Life Origins of Health and Disease

E. Marelyn Wintour-Coghlan,Julie Owens
Early Life Origins of Health and Disease Book PDF

Author : E. Marelyn Wintour-Coghlan,Julie Owens
Publisher : Springer Science & Business Media
Page : 246 pages
File Size : 41,9 Mb
Release : 2007-02-26
Category : Medical
ISBN : 9780387326320

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Early Life Origins of Health and Disease by E. Marelyn Wintour-Coghlan,Julie Owens Pdf

Early Life Origins of Health and Disease is a new book which presents and discusses the many factors that may have impact on normal development. In a concise and readable manner, the authors consider both the proven and suggestive evidence that the high prevalence of hypertension, diabetes, obesity and, in some populations, kidney disease, may not be all due to genetics or adult environment alone. There is good evidence that stress and more subtle dietary deficiencies, as well as placental malfunction, may increase the risk that the offspring will develop these problems in later life. Finally, new and emerging evidence for other areas of human health and disease such a motor control and mental health is critically reviewed for the first time. The book is a ‘must’ for all scientists interested in researching these areas, as there is a critical evaluation of the methodology used and suggestions for the ‘optimal’ way in which to investigate these phenomena.

Calorie Restriction, Aging and Longevity

Arthur V. Everitt,Suresh I. S. Rattan,David G. Couteur,Rafael de Cabo
Calorie Restriction Aging and Longevity Book PDF

Author : Arthur V. Everitt,Suresh I. S. Rattan,David G. Couteur,Rafael de Cabo
Publisher : Springer Science & Business Media
Page : 323 pages
File Size : 41,7 Mb
Release : 2010-06-14
Category : Medical
ISBN : 9048185564

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Calorie Restriction, Aging and Longevity by Arthur V. Everitt,Suresh I. S. Rattan,David G. Couteur,Rafael de Cabo Pdf

Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible in humans because of their long survival. Studies over two to six years in healthy adult humans have, however, shown that a 20% reduction in food or calorie intake slows many indices of normal and disease-related aging. Thus, it is widely believed that long-term reduction in calorie or food intake will delay the onset of age-related diseases such as heart disease, diabetes and cancer, and so prolong life. Over the last 20 or more years there has been a progressive rise in food intake in many countries of the world, accompanied by a rising incidence of obesity. Thus our increasing food and calorie intake has been linked to the rising incidence of cardiovascular disease and diabetes in early adult life. It is accepted that overeating, accompanied by reduced physical exercise, will lead to more age-related diseases and shortening of life-span. The answer is to reduce our calorie intake, improve our diet, and exercise more. But calorie restriction is extremely difficult to maintain for long periods. How then can we solve this problem? Edited by a team of highly distinguished academics, this book provides the latest information on the beneficial effects of calorie restriction on health and life-span. This book brings us closer to an understanding at the molecular, cellular and whole organism level of the way forward.

A Life Course Approach to Healthy Ageing

Diana Kuh,Rachel Cooper,Rebecca Hardy,Marcus Richards,Yoav Ben-Shlomo
A Life Course Approach to Healthy Ageing Book PDF

Author : Diana Kuh,Rachel Cooper,Rebecca Hardy,Marcus Richards,Yoav Ben-Shlomo
Publisher : OUP Oxford
Page : 288 pages
File Size : 44,5 Mb
Release : 2013-12-19
Category : Medical
ISBN : 9780191008177

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A Life Course Approach to Healthy Ageing by Diana Kuh,Rachel Cooper,Rebecca Hardy,Marcus Richards,Yoav Ben-Shlomo Pdf

Healthy ageing has long been a neglected area of epidemiological research as the traditional focus has been on specific chronic diseases of older life. There is a growing consensus from scientists, research funders and policy makers that ageing itself needs to be studied from an interdisciplinary and life course perspective, to inform strategies for reducing the societal and individual costs of an ageing population. A Life Course Approach to Healthy Ageing is a synthesis of life course perspectives in epidemiology and interdisciplinary perspectives in ageing research. It brings together expert investigators of maturing birth cohort and ageing studies, cross-cutting methodologists, and authorities in ageing research and knowledge transfer from across the world in one wide-ranging volume. Contributors discuss how aspects of healthy ageing are conceptualised, defined and measured; relate to each other; change across life; and are influenced by biological, psychological and social factors operating from early life onwards. They identify research gaps, and suggest how evidence from observational studies can be strengthened through improved study design and longitudinal analysis, thereby increasing the research contribution to practice or policy change. The book considers how we might delay or slow down the progressive, generalised impairment of function that occurs at the individual, body system and cellular levels, as people grow older. It also considers the determinants of wellbeing in older people, including personal fulfilment, positive emotions and social relationships. Broad in scope, discussing topics from genetics to psychological and social wellbeing, A Life Course Approach to Healthy Ageing is a key resource for epidemiologists, social scientists, clinicians, public health physicians, policy makers and practitioners with a research interest in healthy ageing.

Aging and the Life Course

Deborah Lowry
Aging and the Life Course Book PDF

Author : Deborah Lowry
Publisher : Rowman & Littlefield
Page : 415 pages
File Size : 41,7 Mb
Release : 2022-01-10
Category : Social Science
ISBN : 9781538143261

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Aging and the Life Course by Deborah Lowry Pdf

Aging & the Life Course: Social & Cultural Contexts provides an accessible, up-to-date introduction to the study of aging and the life course from a distinctly sociological perspective. It explores the sociocultural dimensions of aging while encouraging critical thinking about the diversity of aging experiences, societal attitudes toward older adults, the politics and economics of growing old, and end-of-life resources. Throughout the text, Deborah Lowry emphasizes the relevance of the material for working with older populations, understanding social policy and policy debates, improving communities, relating to others, and understanding ourselves. Organized into four major sections, Part I introduces students to fundamental demographic, sociological, and life course concepts; part II explores the experiences and conditions of aging, especially in particular groups; and part III presents current research on older adults’ engagement in work, family, social networks, and sex. Finally, Part IV addresses themes of aging and social change.

Epigenetics of Aging and Longevity

Alexey Moskalev,Alexander M. Vaiserman
Epigenetics of Aging and Longevity Book PDF

Author : Alexey Moskalev,Alexander M. Vaiserman
Publisher : Academic Press
Page : 544 pages
File Size : 42,8 Mb
Release : 2017-11-17
Category : Medical
ISBN : 9780128110836

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Epigenetics of Aging and Longevity by Alexey Moskalev,Alexander M. Vaiserman Pdf

Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses—including cancer and cardiovascular, metabolic, and neurodegenerative diseases—are explored in detail. This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease. Offers a comprehensive overview of the epigenetic nature of aging, as well as the impact of epigenetic factors on longevity and regulating age-related disease Provides readers with clinical and epidemiological evidence for the role of epigenetic mechanisms in mediating the link between early-life experiences, life-course health and aging trajectory Applies current knowledge of epigenetic regulatory pathways towards developing therapeutic interventions for age-related diseases and extending the human lifespan

Longevity Decoded

Ma Stephen C Schimpff MD
Longevity Decoded Book PDF

Author : Ma Stephen C Schimpff MD
Publisher : Squire Publishing
Page : 202 pages
File Size : 51,5 Mb
Release : 2018-04-08
Category : Electronic
ISBN : 0692064206

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Longevity Decoded by Ma Stephen C Schimpff MD Pdf

You can live a long and healthy life. There is no magic pill or Fountain of Youth, but you can achieve it with simple lifestyle modifications: 1. Eating the right foods 2. Getting the right exercise 3. Reducing and managing stress 4. Improving the quality of sleep 5. Eliminating tobacco 6. Remaining intellectually engaged 7. Staying involved socially The advice in Longevity Decoded works-because it puts you in charge of shaping your future. Everyone wants to live a long and healthy life-Longevity Decoded is your roadmap. The seven keys cost nothing, except your time and commitment. Dr. Stephen Schimpff provides you with straightforward advice for achieving and maintaining good health over a long life. Following his seven keys will pay generous returns over the years ahead, and there's a bonus: You'll become a role model and inspiration to your children and grandchildren! "Dr. Schimpff explores the exciting topic of healthy aging. He combines the science of aging with evidence to suggest how each of us influences our personal journey in life. We make choices every day which impact our health. This book will help you understand how those daily choices will influence your life not only today, but as you get older. Begin today to plan for tomorrow." -James (Jim) M. Anders, Jr., CPA, MBA, CGMA, President and Chairman of the Board, National Senior Campuses, Inc., Administrator and Chief Operating Officer, Kennedy Krieger Institute, Inc. "A highly enjoyable and uplifting read written by a physician with uncommon intellect and wisdom. Certainly, we can all benefit from following Dr. Schimpff's prescription for a healthier and more meaningful life." -R. Alan Butler, Chief Executive Office, Erickson Living "Brilliant work by Dr. Stephen Schimpff yet again! Dr. Schimpff has done a systematic analysis of aging and longevity. His uncanny ability to use data and science together makes his suggestions compelling and convincing, while being insightful. Despite being a complete and thorough account for advanced readers, his book is simple enough to understand for a beginner. If there is only one book you want to read on this subject, it should be this one." -Hiren Doshi, CEO, Paragon Private Health, Co-founder and President, OmniActive Health Technologies "As my age cohort heads toward Medicare, like a veritable tsunami of aging boomers, this text ought to be our navigational guide in the storm. We will want yoga on the lawn, rather than a wheelchair in the garden; we will crave gourmet organic meals, not a nursing home tray!! Dr Schimpff will help us to achieve these dreams with his folksy and reassuring style. This book only confirms for me that the best is yet to come!" -David B. Nash MD, MBA. Founding Dean of the Jefferson College of Population Health "As the world's older population continues to expand at an unprecedented rate, Dr. Schimpff gives readers simple steps that can lay the crucial groundwork for our future health. He provides an optimistic approach to the inevitability of aging and a refreshing perspective that our 'golden years' can also be our 'golden age, ' based on his first-hand experience as a healthcare practitioner." -E. Albert Reece, MD, PhD, MBA, Vice President for Medical Affairs, University of Maryland, John Z. and Akiko K. Bowers Distinguished Professor and Dean, University of Maryland School of Medicine

Epigenetics in Human Disease

Trygve Tollefsbol
Epigenetics in Human Disease Book PDF

Author : Trygve Tollefsbol
Publisher : Academic Press
Page : 617 pages
File Size : 41,6 Mb
Release : 2012-07-26
Category : Medical
ISBN : 9780123884169

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Epigenetics in Human Disease by Trygve Tollefsbol Pdf

Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs

Explaining Divergent Levels of Longevity in High-Income Countries

National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population,Panel on Understanding Divergent Trends in Longevity in High-Income Countries
Explaining Divergent Levels of Longevity in High Income Countries Book PDF

Author : National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population,Panel on Understanding Divergent Trends in Longevity in High-Income Countries
Publisher : National Academies Press
Page : 194 pages
File Size : 45,5 Mb
Release : 2011-06-27
Category : Social Science
ISBN : 9780309217101

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Explaining Divergent Levels of Longevity in High-Income Countries by National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population,Panel on Understanding Divergent Trends in Longevity in High-Income Countries Pdf

During the last 25 years, life expectancy at age 50 in the United States has been rising, but at a slower pace than in many other high-income countries, such as Japan and Australia. This difference is particularly notable given that the United States spends more on health care than any other nation. Concerned about this divergence, the National Institute on Aging asked the National Research Council to examine evidence on its possible causes. According to Explaining Divergent Levels of Longevity in High-Income Countries, the nation's history of heavy smoking is a major reason why lifespans in the United States fall short of those in many other high-income nations. Evidence suggests that current obesity levels play a substantial part as well. The book reports that lack of universal access to health care in the U.S. also has increased mortality and reduced life expectancy, though this is a less significant factor for those over age 65 because of Medicare access. For the main causes of death at older ages -- cancer and cardiovascular disease -- available indicators do not suggest that the U.S. health care system is failing to prevent deaths that would be averted elsewhere. In fact, cancer detection and survival appear to be better in the U.S. than in most other high-income nations, and survival rates following a heart attack also are favorable. Explaining Divergent Levels of Longevity in High-Income Countries identifies many gaps in research. For instance, while lung cancer deaths are a reliable marker of the damage from smoking, no clear-cut marker exists for obesity, physical inactivity, social integration, or other risks considered in this book. Moreover, evaluation of these risk factors is based on observational studies, which -- unlike randomized controlled trials -- are subject to many biases.

Successful Ageing

Clemens Tesch-Romer,Hans-Werner Wahl,Suresh Rattan,Liat Ayalon
Successful Ageing Book PDF

Author : Clemens Tesch-Romer,Hans-Werner Wahl,Suresh Rattan,Liat Ayalon
Publisher : Oxford University Press
Page : 129 pages
File Size : 50,7 Mb
Release : 2021-10-29
Category : Medical
ISBN : 9780192651969

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Successful Ageing by Clemens Tesch-Romer,Hans-Werner Wahl,Suresh Rattan,Liat Ayalon Pdf

The ambition of ageing science to discover the golden fleece of longevity and health is closely connected to the concept of 'successful ageing'. Still, for a large portion of the population, frailty and cognitive impairment is the reality of ageing, and it is by no means certain if health promotion, prevention and other interventions will reduce the probability of its occurrence. This book argues that a narrow understanding of 'successful ageing' as good health, full functioning, and active participation in society excludes a large portion of ageing individuals from the quest for a good life in old age. The challenge is that the term 'successful ageing' comes with ambitions but also with ambivalence. On the one hand, it counteracts the deficit view of ageing and facilitates visionary thinking on what might be possible in the future. On the other hand, its implicitly ageist and derogative features have negative consequences to older people and society at large. So, what is successful ageing? We provide answers at three levels: First, we synthesise the various models used to define successful ageing into a heuristic scheme able to unravel the normative complexity and differences inherent in existing models. Second, we anchor successful ageing models in a tripartite way at micro (individual), meso, and macro analytic levels of human development. Third, we argue that the usefulness of successful ageing in guiding policy will only profit from the concept, if it follows a pluralistic and holistic view without hastily deciding for one model only.

The Biology of Human Longevity

Caleb E. Finch
The Biology of Human Longevity Book PDF

Author : Caleb E. Finch
Publisher : Elsevier
Page : 640 pages
File Size : 51,5 Mb
Release : 2010-07-28
Category : Medical
ISBN : 0080545947

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The Biology of Human Longevity by Caleb E. Finch Pdf

Written by Caleb Finch, one of the leading scientists of our time, The Biology of Human Longevity: Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes several decades of top research on the topic of human aging and longevity particularly on the recent theories of inflammation and its effects on human health. The book expands a number of existing major theories, including the Barker theory of fetal origins of adult disease to consider the role of inflammation and Harmon's free radical theory of aging to include inflammatory damage. Future increases in lifespan are challenged by the obesity epidemic and spreading global infections which may reverse the gains made in lowering inflammatory exposure. This timely and topical book will be of interest to anyone studying aging from any scientific angle. Author Caleb Finch is a highly influential and respected scientist, ranked in the top half of the 1% most cited scientists Provides a novel synthesis of existing ideas about the biology of longevity and aging Incorporates important research findings from several disciplines, including Gerontology, Genomics, Neuroscience, Immunology, Nutrition

Senolytics in Disease, Ageing and Longevity

Daniel Muñoz-Espin,Marco Demaria
Senolytics in Disease Ageing and Longevity Book PDF

Author : Daniel Muñoz-Espin,Marco Demaria
Publisher : Springer Nature
Page : 226 pages
File Size : 54,6 Mb
Release : 2020-04-27
Category : Science
ISBN : 9783030449032

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Senolytics in Disease, Ageing and Longevity by Daniel Muñoz-Espin,Marco Demaria Pdf

This book offers comprehensive information on the new and rapidly evolving science of identifying and targeting senescent cells, and on the exciting prospect of new diagnostic and therapeutic opportunities for stopping, and even reversing, the progression of disease and the deterioration of the human body due to ageing. According to recent United Nations data, by 2050 one in six people worldwide will be older than age 65, with peaks rising to one in four people in Europe and North America. Remarkably, the number of persons aged 80 years or older is expected to triple, from 143 million in 2019 to 426 million in 2050. First documented in the 1960s, the concept of cellular senescence as an underlying cause of ageing has been established in the course of the last decade. Using genetically engineered mouse models, researchers have demonstrated that the selective elimination of senescent cells can block and even reverse a number of age-related dysfunctions and pathologies, promoting both better health and longer life in the elderly. These include cardiovascular diseases; neurological disorders; type 1 and type 2 diabetes; inflammatory diseases; fibrosis; geriatric syndromes; chronic diseases resulting in organ dysfunction; the integrity of the musculoskeletal system; and cancer. Some senolytic agents have already progressed into trials. These include UBX0101 for the treatment of osteoarthritis (now in phase II), a cocktail of dasatinib and quercetin for the management of idiopathic pulmonary fibrosis and chronic kidney disease, and ABT-263 in combination with senescence-inducing chemotherapies for the treatment of advanced solid tumours. In addition, the book discusses pathways to early phase clinical trials and translational approaches in medicine and ageing, highlighting new opportunities as well as current limitations, challenges and alternatives. Given its scope, it will benefit a broad audience of advanced educators, researchers, graduate students and practitioners.

Aging, Health, and Longevity in the Mexican-Origin Population

Jacqueline L. Angel,Fernando Torres-Gil,Kyriakos Markides
Aging Health and Longevity in the Mexican Origin Population Book PDF

Author : Jacqueline L. Angel,Fernando Torres-Gil,Kyriakos Markides
Publisher : Springer Science & Business Media
Page : 353 pages
File Size : 44,6 Mb
Release : 2012-02-09
Category : Family & Relationships
ISBN : 9781461418665

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Aging, Health, and Longevity in the Mexican-Origin Population by Jacqueline L. Angel,Fernando Torres-Gil,Kyriakos Markides Pdf

Aging, Health, and Longevity in the Mexican-Origin Population creates a foundation for an interdisciplinary discussion of the trajectory of disability and long-term care for older people of Mexican-origin from a bi-national perspective. Although the literature on Latino elders in the United States is growing, few of these studies or publications offer the breadth and depth contained in this book.

The Age of Longevity

Rosalind C. Barnett,Caryl Rivers
The Age of Longevity Book PDF

Author : Rosalind C. Barnett,Caryl Rivers
Publisher : Rowman & Littlefield
Page : 274 pages
File Size : 53,9 Mb
Release : 2016-08-22
Category : Self-Help
ISBN : 9781442255289

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The Age of Longevity by Rosalind C. Barnett,Caryl Rivers Pdf

Long, productive lives are the destiny of most of us, not just the privilege of our great-grandchildren. The story of aging is not one of steady decline and decay; we need a new narrative based on solid research, not scare stories. Today Americans enjoy a new, healthy stage of life, between roughly 65 and 79, during which we are staying engaged in the workplace, starting new relationships and careers, remaining creative and becoming entrepreneurs and job creators. We are in the midst of a major paradigm shift in the way we live. Our major milestones are shifting. The definition of “normal” behavior is changing. Today, we marry later or not at all; cohabitation is not just a stepping stone to marriage, but a long-term arrangement for many. Women often have their first child in their 40s, and increasingly before they marry. People enjoy active sex lives well into their 6th, 7th or even 8th decades. None of our institutions will remain the same. People are working longer, and given the declining birth rate, older workers will be in great demand. Four generations are increasingly working side by side, learning from each other. But we must ensure that the benefits of long life are not limited to a wealthy few. The Age of Longevity shows how we as a society can embrace the life-altering changes that are either coming in the near future or are already underway. The authors give readers a panoramic view of how they, the institutions that affect them, and the country as a whole will need to adapt to what’s ahead. They offer strategies, based on cutting-edge research, that will enable individuals, institutions, companies, and governments to make the most of our lengthening life spans. Using real life examples throughout, the authors paint a picture of what our new longer lives will look like, and the changes that need to be made so we can all make those years both more productive and more enjoyable.