Embryos Genes And Birth Defects

Author : Patrizia Ferretti,Andrew Copp,Cheryll Tickle,Gudrun Moore
Publisher : John Wiley & Sons
Page : 562 pages
File Size : 52,6 Mb
Release : 2006-08-04
Category : Science
ISBN : 9780470090114

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Embryos, Genes and Birth Defects by Patrizia Ferretti,Andrew Copp,Cheryll Tickle,Gudrun Moore Pdf

The first edition of Embryos, Genes and BirthDefects, edited by the late Peter Thorogood, was a radicalnew book aimed at bridging the gap between the medical disciplinesof embryology and dysmorphology, and recent advances in cellular,molecular and developmental biology. This new edition remainsunique in its breadth and brings up to date our understanding ofbirth defects and of the strategies utilized to gain suchknowledge. It features new chapters on human cytogenetics,mutagenesis and the eyes and ears. The book presents key topics in developmental biology andexplains how they provide the foundations for understandingclinical birth defects. The first six chapters introduce conceptsand strategies adopted to elucidate developmental anomalies leadingto birth defects. The book then focuses on specific organs andreviews the cellular and molecular mechanisms affecting theirdevelopment and how disruption of these mechanisms by genetic orenvironmental factors may underlie certain birth defects. Thechapters are concise and provide up-to-date coverage of topics in aformat that is easily accessible and yet at the forefront ofresearch. Written primarily for paediatricians, obstetricians, clinicalgeneticists and allied workers, this book guides the reader throughthe contribution of modern molecular biology to our understandingof human development. Developmental and cellular biologists willlearn how errors in the cellular and genetic mechanism can lead toclassical disorders, diseases and syndromes.

Author : Keith L. Moore,T. V. N. Persaud,Mark G. Torchia
Publisher : Elsevier Health Sciences
Page : 1111 pages
File Size : 49,6 Mb
Release : 2011-12-28
Category : Medical
ISBN : 9781455707508

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Before We Are Born by Keith L. Moore,T. V. N. Persaud,Mark G. Torchia Pdf

Before We Are Born: Essentials of Embryology and Birth Defects, by Drs. Keith L. Moore, T.V.N. Persaud, and Mark G. Torchia, allows you to efficiently and quickly assimilate the most important concepts related to this subject. Concise and richly illustrated, this popular book delivers the embryology knowledge you need in a highly efficient, reader-friendly manner. Focus on the most need-to-know information with coverage masterfully distilled from The Developing Human, 8th Edition - the more comprehensive and in-depth embryology textbook by Drs. Moore, Persaud, and Torchia. Study efficiently and flexibly thanks to the book’s user-friendly full-color format and portable size. Effectively prepare for exams with review questions and answers at the end of each chapter. Understand all of the latest advances in embryology, including normal and abnormal embryogenesis, causes of birth defects, and the role of genes in human development. See how discoveries in molecular biology have affected clinical practice, including the development of sophisticated new techniques such as recumbent DNA technology and stem cell manipulation. Prepare for the USMLE Step 1 with clinical case presentations, highlighted in special boxes, that demonstrate how embryology concepts relate to clinical practice.

Author : Keith L. Moore,T. V. N. Persaud,Mark G. Torchia
Publisher : Elsevier Health Sciences
Page : 462 pages
File Size : 53,5 Mb
Release : 2015-01-21
Category : Medical
ISBN : 9780323313407

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Before We Are Born E-Book by Keith L. Moore,T. V. N. Persaud,Mark G. Torchia Pdf

As the study of embryology continues to be integrated with a range of disciplines, Before We Are Born remains the ideal solution for students who need to quickly learn the basics. Fully updated by the world’s foremost embryologists, this medical reference book provides concise guidance on human embryology at every stage of development, utilizing rich illustrations and photographs designed to further explain content. Understand all of the latest advances in embryology, including normal and abnormal embryogenesis, causes of birth defects, and the role of genes in human development. See how discoveries in molecular biology have affected clinical practice, including the development of sophisticated new techniques such as recumbent DNA technology and stem cell manipulation. Prepare for the USMLE Step 1 with clinical case presentations, highlighted in special boxes, which demonstrate how embryology concepts relate to clinical practice. Quickly review just the embryology information you need to know, masterfully distilled from the popular book The Developing Human, written by the same author team. Understand the complex concepts inherent in embryology with help from streamlined content, didactic illustrations, and clinical photos. Test your knowledge with brand-new review questions at the end of each chapter.

Author : National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology
Publisher : National Academies Press
Page : 348 pages
File Size : 45,9 Mb
Release : 2000-12-21
Category : Nature
ISBN : 9780309070867

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Scientific Frontiers in Developmental Toxicology and Risk Assessment by National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology Pdf

Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

Author : James Graves Wilson
Publisher : Unknown
Page : 328 pages
File Size : 40,8 Mb
Release : 1973
Category : Medical
ISBN : UOM:39015003808014

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Environment and Birth Defects by James Graves Wilson Pdf

Author : Ian H. Porter,Norma H. Hatcher,Ann M. Willey
Publisher : Elsevier
Page : 320 pages
File Size : 42,6 Mb
Release : 2013-09-03
Category : Medical
ISBN : 9781483264486

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Perinatal Genetics by Ian H. Porter,Norma H. Hatcher,Ann M. Willey Pdf

Perinatal Genetics: Diagnosis and Treatment brings together the proceedings of the 15 Annual New York State Health Department Birth Defects Symposium held on September 30-October 1, 1984 in Albany, New York. The symposium provided a forum for clarifying and rationalizing certain aspects of diagnosis and treatment of perinatal genetic birth defects such as fragile X syndrome, phenylketonuria, and hypothyroidism. Comprised of 17 chapters, this book begins with an epidemiological review of very early pregnancy loss, focusing on fertilization and implantation; the probability of loss between fertilization and implantation (on about the sixth day), and between implantation and the 14th day (the first day of the expected next period in a non-pregnant woman); and the contribution of chromosomal errors in the sperm, ovum, and zygote to early reproductive loss. The reader is then introduced to cytogenetic abnormalities in spontaneous abortions of recognized conceptions; repetitive spontaneous abortion; and prenatal genetic diagnosis by chorionic villus sampling. Subsequent chapters explore prenatal treatment of biochemical disorders; in vitro fertilization and embryo transfer; and moral issues concerning third trimester pregnancy terminations. This monograph will appeal to perinatologists, neonatologists, obstetricians, pediatricians, and geneticists and should also serve as a useful guide for health professionals who provide care to pregnant women and their newborns.

Author : Genetic Alliance,New York-Mid-Atlantic Consortium for Genetic and Newborn Screening Services
Publisher : Lulu.com
Page : 104 pages
File Size : 44,7 Mb
Release : 2009
Category : Biology
ISBN : 9780982162217

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Understanding Genetics by Genetic Alliance,New York-Mid-Atlantic Consortium for Genetic and Newborn Screening Services Pdf

The purpose of this manual is to provide an educational genetics resource for individuals, families, and health professionals in the New York - Mid-Atlantic region and increase awareness of specialty care in genetics. The manual begins with a basic introduction to genetics concepts, followed by a description of the different types and applications of genetic tests. It also provides information about diagnosis of genetic disease, family history, newborn screening, and genetic counseling. Resources are included to assist in patient care, patient and professional education, and identification of specialty genetics services within the New York - Mid-Atlantic region. At the end of each section, a list of references is provided for additional information. Appendices can be copied for reference and offered to patients. These take-home resources are critical to helping both providers and patients understand some of the basic concepts and applications of genetics and genomics.

Author : James Wynbrandt,Mark D. Ludman
Publisher : Infobase Publishing
Page : 705 pages
File Size : 53,8 Mb
Release : 2010-05-12
Category : Juvenile Nonfiction
ISBN : 9781438120959

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The Encyclopedia of Genetic Disorders and Birth Defects by James Wynbrandt,Mark D. Ludman Pdf

Presents information on congenital birth defects, giving the name, known or suspect cause and brief description as well as available treatments where applicable.

Author : Howard M. Lenhoff
Publisher : Unknown
Page : 404 pages
File Size : 48,6 Mb
Release : 1989
Category : Human reproduction
ISBN : UOM:39076001752752

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Conception to Birth by Howard M. Lenhoff Pdf

Author : Gregory R. Bock,Joan Marsh
Publisher : John Wiley & Sons
Page : 310 pages
File Size : 42,6 Mb
Release : 2008-04-30
Category : Science
ISBN : 9780470514566

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Neural Tube Defects by Gregory R. Bock,Joan Marsh Pdf

Neural tube defects are the second most common cause of perinatal death from birth defects in the United Kingdom. In this important book, leading scientists evaluate the latest evidence on the causative factors--both genetic and environmental--of these major human congenital malformations. They also discuss prospects for early detection by prenatal screening and for treatment both before and after birth. The extensive coverage encompasses such topics as: formation and patterning of the avian neuraxis, neurulation in mammals and the normal human embryo, folic acid and more.

Author : Lisa Iannucci
Publisher : Enslow Publishing
Page : 134 pages
File Size : 40,5 Mb
Release : 2000
Category : Juvenile Nonfiction
ISBN : 0766011860

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Birth Defects by Lisa Iannucci Pdf

Explains what birth defects are, efforts to treat and prevent them, and the diagnosis of genetic and environmentally caused birth defects.

Author : The Royal Society,National Academy of Sciences,National Academy of Medicine,International Commission on the Clinical Use of Human Germline Genome Editing
Publisher : National Academies Press
Page : 239 pages
File Size : 47,6 Mb
Release : 2021-01-16
Category : Medical
ISBN : 9780309671132

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Heritable Human Genome Editing by The Royal Society,National Academy of Sciences,National Academy of Medicine,International Commission on the Clinical Use of Human Germline Genome Editing Pdf

Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

Author : Aubrey Milunsky,Jeff M. Milunsky
Publisher : John Wiley & Sons
Page : 1208 pages
File Size : 41,7 Mb
Release : 2015-09-16
Category : Medical
ISBN : 9781118981535

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Genetic Disorders and the Fetus by Aubrey Milunsky,Jeff M. Milunsky Pdf

Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment, Seventh Edition is the eagerly awaited new edition of the discipline-leading text that has been at the forefront of diagnosis, prevention, and treatment of fetal genetic disorders for over 36 years. The seventh edition continues the long-established tradition of excellence that has become synonymous with this text. The book builds on the foundations of preconception and prenatal genetic counseling and the original pillars of prenatal diagnosis while also providing authoritative coverage of exciting developments in non-invasive genetic testing and rapidly developing molecular techniques, including microarray analysis and next generation sequencing, that are revolutionizing the field. Chapters are once again authored by internationally recognized authorities in the field of prenatal diagnosis. The editors have added three entirely new chapters to this edition to complement the complete revision of existing content. The three new chapters focus on non-invasive prenatal screening, placental genetics, and the psychology of prenatal and perinatal grief. The broad-ranging coverage and international scope will ensure that the new edition maintains its role as the major repository for information on all aspects of prenatal diagnosis. The editors have brought together an invaluable collection of evidence-based facts bolstered by knowledge and decades of experience in the field. Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment, 7th Edition is a timely update to this world-leading text.

Author : Aubrey Milunsky,Jeff M. Milunsky
Publisher : John Wiley & Sons
Page : 1494 pages
File Size : 49,9 Mb
Release : 2011-09-07
Category : Medical
ISBN : 9781444358216

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Genetic Disorders and the Fetus by Aubrey Milunsky,Jeff M. Milunsky Pdf

Highly Commended in the Obstetrics and Gynaecology category of the 2010 BMA Medical Book Competition Brand new edition of the world's leading text on prenatal diagnosis This 6th Edition of Genetic Disorders and the Fetus maintains it's pre-eminence as the major repository of facts about prenatal diagnosis. It provides a critical analysis and synthesis of established and new knowledge based on the long experience of authorities in their respective fields. A broad international perspective is presented through authoritative contributions from authors in 11 countries. All chapters and guidelines have been updated to reflect contemporary practice. New chapters have been introduced on: The use of chromosomal microarrays in prenatal diagnosis The social, legal and public policy issues with special reference to international approaches The important peroxisomal and related fatty acid oxidation disorders Extensive tables and clear illustrations assist in differential diagnosis, gene identification and diagnostic modes. The recognition of many new and unresolved challenges should provide inspiration for novel research initiatives. The guidance provided and the insights and perspectives of these authors make this volume a valuable and indispensable resource for all whose focus is securing fetal health through prenatal diagnosis. Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment is an essential resource for all engaged in prenatal genetic diagnosis, especially obstetricians, maternal-fetal medicine specialists, medical geneticists, genetic counsellors, and pediatricians, but also many other specialties.

Author : Keith L. Moore,T. V. N. Persaud,Mark G. Torchia
Publisher : Elsevier Health Sciences
Page : 370 pages
File Size : 46,9 Mb
Release : 2019-09-06
Category : Medical
ISBN : 9780323608503

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Before We Are Born - E-Book by Keith L. Moore,T. V. N. Persaud,Mark G. Torchia Pdf

Covering the essentials of normal and abnormal human development for students in a variety of health science disciplines, Before We Are Born: Essentials of Embryology and Birth Defects, 10th Edition, reflects new research findings and current clinical practice through concise text and abundant illustrations. This edition has been fully updated by the world’s foremost embryologists and is based on the popular text, The Developing Human, written by the same author team. It provides an easily accessible understanding of all of the latest advances in embryology, including normal and abnormal embryogenesis, causes of birth defects, and the role of genes in human development. Features streamlined content throughout, numerous photographs of common clinical cases and embryological explanations, didactic illustrations, and nearly 700 USMLE-style questions with full answers and explanations to help prepare for professional exams. Includes interactive clinical cases in every chapter that make important connections between human development and clinical practice—ideal for preparing for USMLE Step 1. Includes many new color photographs, new diagnostic images (3D ultrasound, CT scans, and MR images), an updated teratology section, revised and highlighted information on molecular aspects of developmental biology, and new information on the cellular and molecular basis of embryonic development. Follows the official international list of embryological terms (Terminologia Embryonica, 2013).