Epidemiology Pathogenesis And Prevention Of Head And Neck Cancer
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Author : Andrew F. Olshan Publisher : Springer Science & Business Media Page : 211 pages File Size : 48,6 Mb Release : 2010-03-04 Category : Medical ISBN : 9781441914712
Epidemiology, Pathogenesis, and Prevention of Head and Neck Cancer by Andrew F. Olshan Pdf
The purpose of this book is to provide a current perspective on the epidemiology head and neck cancer. Cancers of the oral cavity, pharynx, and larynx comprise an important group of tumors with diverse international patterns of incidence and mortality, established risk factors, suggested association with a virus, and potential genetic susceptibility determinants. These tumors offer a unique insight into mechanisms of cancer initiation and progression and gene-exposure interaction.
Epidemiology, Pathogenesis, and Prevention of Head and Neck Cancer by Andrew F. Olshan Pdf
Epidemiology, Pathogenesis, and Prevention of Head and Neck Cancer provides a current perspective on the epidemiology of head and neck cancer. Cancers of the oral cavity, pharynx, and larynx comprise an important group of tumors with diverse international patterns of incidence and mortality, established associations with tobacco and alcohol use, the human papilloma virus, and potential determinants of genetic susceptibility. Because of these factors, head and neck cancer offers a unique insight into mechanisms of cancer initiation and progression and gene-exposure interaction. This book brings together the latest epidemiologic and molecular genetic evidence regarding the patterns of occurrence and causes of head and neck cancer. In addition, Epidemiology, Pathogenesis, and Prevention of Head and Neck Cancer considers approaches to chemoprevention, and incorporates a multidisciplinary perspective including salient clinical, pathologic, molecular, and epidemiologic contributions.
Head and Neck Cancer by Bruce Brockstein,Gregory Masters Pdf
Exciting advances are occurring in the understanding of the molecular pathogenesis of squamous head and neck cancers. Epidemiology, staging and screening, as well as premalignancy, chemoprevention and the molecular biology of head and neck cancer, lay the groundwork for the understanding of the clinical chapters that follow. Controversial treatments will be compared to the standard management of patient care. Therapy chapters are divided into stage or category specific (resectable advanced, unresectable advanced or metastatic) problems, allowing the reader to review the current standards and options for patient types or specific patients easily. Considerations of supportive care, late toxicities and quality of life, often overlooked are reviewed in detail. This is a comprehensive summary of the current state of the art research and treatment.
Michael J. Thun,Martha S. Linet,James R. Cerhan,Christopher A. Haiman,David Schottenfeld
Author : Michael J. Thun,Martha S. Linet,James R. Cerhan,Christopher A. Haiman,David Schottenfeld Publisher : Oxford University Press Page : 1329 pages File Size : 54,8 Mb Release : 2017-11-14 Category : Medical ISBN : 9780190238667
Michael Thun,Martha S. Linet,James R. Cerhan,Christopher A. Haiman,David Schottenfeld
Author : Michael Thun,Martha S. Linet,James R. Cerhan,Christopher A. Haiman,David Schottenfeld Publisher : Oxford University Press Page : 1104 pages File Size : 43,7 Mb Release : 2017-11-07 Category : Medical ISBN : 9780190238674
Cancer Epidemiology and Prevention by Michael Thun,Martha S. Linet,James R. Cerhan,Christopher A. Haiman,David Schottenfeld Pdf
"The definitive reference for budding and experienced cancer epidemiologists alike." -American Journal of Epidemiology "Practitioners in epidemiology and oncology will find immense value in this." -JAMA Since its initial publication in 1982, CANCER EPIDEMIOLOGY AND PREVENTION has served as the premier reference work for students and professionals working to understand the causes and prevention of cancer in humans. Now revised for the first time in more than a decade, this fourth edition provides a comprehensive summary of the global patterns of cancer incidence and mortality, current understanding of the major causal determinants, and a rationale for preventive interventions. Special attention is paid to molecular epidemiologic approaches that address the wider role of genetic predisposition and gene-environment interactions in cancer etiology and pathogenesis. New and timely chapters on environmental and social-epidemiologic factors include: · The role of social class disparities · The role of obesity and physical inactivity · The potential effects of electromagnetic fields and radiofrequency radiation · The principles of cancer chemoprevention For both seasoned professionals and newer generations of students and researchers, this fourth edition of CANCER EPIDEMIOLOGY AND PREVENTION remains the authority in the field -- a work of distinction that every lab, library, student, professional, or researcher should have close at hand.
Head and Neck Cancers by Athanassios Argiris, MD, FACP,Robert L. Ferris, MD, PhD, FACS,David I. Rosenthal, MD, FACR, FASTRO Pdf
“Overall, this is an excellent book on an important topic in cancer that medical oncologists, pharmacologists, and nurses, as well as related healthcare professionals, may find very helpful.” Score: 100, 5 Stars, Doody’s Medical Reviews Head and Neck Cancers: Evidence-Based Treatment presents a practical, state-of-the-art resource for any clinical oncologist treating or managing patients with head and neck cancers, including oropharyngeal cancer, cancer of the oral cavity, laryngeal cancer, nasopharyngeal cancer, hypopharyngeal cancer, cancer of the sinuses and the skull base, salivary gland cancer, and neck lymphadenopathy. Section 1 of the book covers the most pertinent details on the epidemiology, biology, diagnosis and staging of the disease including topics such as the genomic landscape of squamous cell carcinoma of the head and neck and novel imaging modalities. Section 2 discusses the evidence-based treatment modalities for conventional and novel chemotherapy regimens, the evidence behind emerging radiation therapy techniques and the minimally invasive surgical advances changing the landscape of care. The chapters in Section 3 are dedicated to site-specific management, including management guidelines, tables with FDA-approved therapies and relevant ongoing clinical trials as well as instructive clinical cases with important discussion on outcomes and follow up care. Finally, Section 4 focuses on recurrent and metastatic disease and Section 5 provides the essentials on supportive care, including managing the elderly, managing patients suffering from dysphagia and oral complications, and must-know details of quality of life assessment and patient-reported outcomes. Emphasizing the practice-changing techniques and the latest evidence-based treatment advances including targeted therapies, immunotherapy, transoral robotic surgery, and radiation therapy precision, this comprehensive yet accessible textbook is indispensable for any clinical oncologist of each discipline wanting a balanced and evidence-based reference on managing patients with head and neck malignancies. Key Features: Includes didactic clinical cases for each type of head and neck cancer Numerous tables highlight FDA approved therapies and ongoing clinical trials Provides evidence-based recommendations for treating head and neck cancers at each stage of the disease with conventional and novel treatment strategies Covers strategies for managing acute and late complications to treatment
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author : Jochen A. Werner,R. Kim Davis Publisher : Springer Science & Business Media Page : 233 pages File Size : 47,8 Mb Release : 2012-12-06 Category : Medical ISBN : 9783642187223
Metastases in Head and Neck Cancer by Jochen A. Werner,R. Kim Davis Pdf
-Richly illustrated; 109 illustrations, 57 in color -Cover a wide range of diagnostic and theraputic techniques, i.e. MRI, PET, surgical treatment, radiation therapy
Oral and Maxillofacial Surgery by Gokul Sridharan Pdf
Oral and maxillofacial surgery is a specialized branch of dentistry that deals with the surgical management of various head and neck pathologies. The specialty focuses on reconstructive surgery of the oro-facial region, surgery of facial trauma, the oral cavity and jaws, dental implants as well as cosmetic surgery. As such, surgeons in this field require extensive knowledge of not only these various surgical procedures but also head and neck anatomy. This book provides comprehensive information on both. Its goal is to educate oral and maxillofacial surgeons to enable them to treat a wide range of conditions and diseases using the most current surgical trends.
Textbook of Cancer Epidemiology by Hans-Olov Adami,David J. Hunter,Pagona Lagiou,Lorelei Mucci Pdf
"Comprehensive and comprehensible, but also encouraging -- informed by the hope and belief that informed its creation." -Cancer Amid sweeping advances in the science and treatment of cancer, the TEXTBOOK OF CANCER EPIDEMIOLOGY offers students and professionals a definitive, systematic resource for understanding the factors affecting all types of human cancer. This fully updated new edition offers an overview of epidemiology's key concepts and methods as they relate to cancer (including the emerging potential of biomarkers) as well as site-specific chapters on individual cancers' natural history, pathology, descriptive epidemiology, and etiology. Taken together, these chapters forge connections between established science and the ongoing evolution of this dynamic field. Crisply and concisely written by an assembly of internationally recognized researchers, the TEXTBOOK OF CANCER EPIDEMIOLOGY offers a superlative introduction to the subject's consensuses and controversies for those embarking on their careers and a ready reference for seasoned professionals.
Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.
Author : James A. Radosevich Publisher : Springer Science & Business Media Page : 198 pages File Size : 55,8 Mb Release : 2012-12-14 Category : Medical ISBN : 9789400754379
“HPV and Cancer” is a concise read that covers all aspects of the Human Papilloma Virus as it relates to human cancers. While written by professionals, it design to be understandable by those that are not in the field, yet it has the technical details that professionals want to stay abreast of this changing field. The book starts out the history of HPV and progresses into the molecular biology of the virus and our current understand of the structure and functions of the proteins and genes it encodes. We then look at the dynamic trends of this infectious agent in the human population, how it interacts with human cells, and the role it plays with other organisms to produce both benign and malignant tumors. Lastly, there is a discussion about a new vaccine for HPV and the hopes that are held by many to change the trends with this virus and the associated cancers it produces.
Head and Neck Critical Illness by Hiroyuki Tomita Pdf
There are various malignant tumors in the head and neck area, including oral cavity, pharynx, sinonasal cavity, and salivary glands. Squamous cell carcinoma is the most common cancer among head and neck cancers. In salivary glands, there are many types of malignancies that can develop, such as malignant lymphoma, adenoid cystic carcinoma, adenocarcinoma, and mesenchymal tumors. In a clinical setting, imaging, such as computed tomography (CT) and magnetic resonance imaging (MRI), is very important in terms of the prediction of the histological type and the evaluation of the extent of invasion of adjacent structures. In basic research, there are few animal models in head and neck malignancies. In this Special Issue, we broadly discuss the basic and clinical research in head and neck malignancies.
An Evidence-Based Approach to the Management of Nasopharyngeal Cancer by Baharudin Abdullah,Anusha Balasubramanian,Norhafiza Mat Lazim Pdf
An Evidence-Based Approach to the Management of Nasopharyngeal Cancer: From Basic Science to Clinical Presentation and Treatment provides a comprehensive overview with updated management procedures for nasopharyngeal carcinoma. Written by experts on the subject, it is organized in a simple yet comprehensive manner to aid in the understanding of this complex condition. The book discusses several topics related to NPC, including epidemiology, pathophysiology, risk factors and treatment (surgical and non-surgical). Additionally, it discusses key features of clinical presentation of NPC, recent advances and promising new therapies. This will be a valuable source for clinicians, graduate students, oncologists and several members of the biomedical field who are interested in understanding nasopharyngeal cancer in a practical and applicable way. Discusses current trends in surgery, including the use of endoscopy and robotic and navigation technology in the management of NPC Presents a summary with diagrams and workflows at the end of every chapter as a quick reference guide Encompasses colorful figures of pathology, clinical cases, endoscopic findings, surgical approaches, resection of tumors, brachytherapy and robotic and navigation technology so readers fully comprehend content
Author : Louis B. Harrison,Roy B. Sessions,Merrill S. Kies Publisher : Lippincott Williams & Wilkins Page : 2184 pages File Size : 49,7 Mb Release : 2013-07-17 Category : Medical ISBN : 9781469830902
Head and Neck Cancer by Louis B. Harrison,Roy B. Sessions,Merrill S. Kies Pdf
–Comprehensive, multi-disciplinary text addressing all aspects of head and neck cancer and crosses a wide spectrum of specialists, including surgical, radiation and medical oncologists, dentists, pathologists, radiologists, and nurses. –8 new chapters – 9 with new authors –Revisions highlight new techniques and imaging –New imaging emphasizes diagnostics, image guided therapies, follow-up imaging, and novel imaging approaches –Less basic science and more clinical diagnostics and management –25% new illustrations, along with more color images to assist in diagnostics and therapeutics
