Exosomes In Cardiovascular Diseases

Author : Junjie Xiao,Sanda Cretoiu
Publisher : Springer
Page : 307 pages
File Size : 52,5 Mb
Release : 2017-09-19
Category : Science
ISBN : 9789811043970

Get Book

Exosomes in Cardiovascular Diseases by Junjie Xiao,Sanda Cretoiu Pdf

The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Thirdly, exosomes as biomarkers of cardiovascular diseases are overviewed including their roles in diagnosis, prognosis and reaction to therapy. Fourthly, pathological effects of exosomes and therapeutic effects of exosomes are highlighted. Finally, future prospects of exosomes in cardiovascular research would be provided. This is an essential reference for researchers working in cell biology and regeneration, as well as clinicians such as cardiologist.

Author : Hongyun Wang,Junjie Xiao,Yunlong Huang
Publisher : Frontiers Media SA
Page : 151 pages
File Size : 51,8 Mb
Release : 2022-11-23
Category : Medical
ISBN : 9782832506905

Get Book

Exosomes in Cardiovascular Diseases: Mechanism, Diagnosis and Therapy by Hongyun Wang,Junjie Xiao,Yunlong Huang Pdf

Author : Rory R. Koenen,Elena Aikawa
Publisher : Frontiers Media SA
Page : 118 pages
File Size : 47,8 Mb
Release : 2018-10-19
Category : Cardiovascular system
ISBN : 9782889456208

Get Book

Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases by Rory R. Koenen,Elena Aikawa Pdf

It is long known that many cells can shed extracellular vesicles, small membrane-enclosed cell fragments. Although the existence of extracellular vesicles has been recognized for many years, researchers are only beginning to understand their physiologic significance. Several recent studies have demonstrated that extracellular vesicles released from cells serve as a mode of cellular communication. They can carry diverse molecular payload (e.g. nucleic acids, bioactive lipids and proteins) to distal organs and recipient cells. Extracellular vesicles can be classified into three major groups: exosomes, microvesicles, and apoptotic bodies. All these types of extracellular vesicles can be found in a variety of biologic specimen and their numbers, distribution and composition may serve as biomarkers for various disorders, including cardiovascular disease. Although extracellular vesicle-mediated processes are currently best characterized in the fields of cancer biology and neurobiology, evidence is accumulating that extracellular vesicles play a key role in the pathophysiology of diabetes, thrombosis, inflammation and cardiovascular calcification. In this Research Topic, we invited review and methodological articles that advance our understanding of extracellular vesicle-related processes in vascular biology.

Author : Junjie Yang,Zhen-Ao Zhao,Zhongjian Cheng,Phuong-Uyen Dinh,Ke Huang,Zhenhua Li
Publisher : Frontiers Media SA
Page : 224 pages
File Size : 50,8 Mb
Release : 2023-05-26
Category : Medical
ISBN : 9782832524176

Get Book

Extracellular vesicles in cardiovascular diseases by Junjie Yang,Zhen-Ao Zhao,Zhongjian Cheng,Phuong-Uyen Dinh,Ke Huang,Zhenhua Li Pdf

Author : Yaoliang Tang,Buddhadeb Dawn
Publisher : Academic Press
Page : 288 pages
File Size : 41,5 Mb
Release : 2015-09-02
Category : Medical
ISBN : 9780128004975

Get Book

Mesenchymal Stem Cell Derived Exosomes by Yaoliang Tang,Buddhadeb Dawn Pdf

Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies

Author : Larry Edelstein,John R. Smythies,Peter J. Quesenberry,Denis Noble
Publisher : Academic Press
Page : 548 pages
File Size : 46,7 Mb
Release : 2019-10-16
Category : Science
ISBN : 9780128160541

Get Book

Exosomes by Larry Edelstein,John R. Smythies,Peter J. Quesenberry,Denis Noble Pdf

Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomes in the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medical disciplines, as well as their role in cell-cell communication. It is intended to serve as a reference source for clinicians, physicians, and research scientists who wish to gain insight into the most recent advances in this rapidly growing field. The exosome revolution may well be the greatest advance in physiology and medicine since antibiotics. The discovery of their epigenetic role in intercellular signaling in virtually all tissues is a major breakthrough in our understanding of how cells function. Provides readers with a broad and timely overview of exosomes in health and disease, closing with a thought-provoking chapter on transgenerational inheritance, Darwin and Lamarck. Summarizes the most recent laboratory and clinical findings on exosomes across numerous medical disciplines, thereby offering readers a broad-ranging and solid foundation for prospective investigative efforts Twenty-one chapters authored by a global team of peer-acknowledged experts, each representing a key medical disciplineProvides readers with a broad and timely overview of exosomes in health and disease, closing

Author : Junjie Xiao
Publisher : Springer Nature
Page : 272 pages
File Size : 53,5 Mb
Release : 2023-09-22
Category : Medical
ISBN : 9789819914432

Get Book

Extracellular Vesicles in Cardiovascular and Metabolic Diseases by Junjie Xiao Pdf

This book provides the latest research progress on Extracellular vesicles (EVs) in cardiovascular and metabolic diseases. EVs are small bilayer lipid membrane vesicles released by cells and function for intercellular communication. Increasing evidence has shown that EVs play crucial roles in cardiovascular and metabolic diseases, which seriously threaten human health worldwide. The book contains four sections: 1) Extraction Methods; 2) EVs in Cardiovascular Diseases; 3) EVs in Metabolic Diseases; and 4) Therapeutic Implications. This book is useful for biologists, cardiologists, cardiovascular surgeons, endocrinologists, internists, nurses, undergraduate and graduate students in medicine and cell biology, and others interested in cardiovascular and metabolic medicine.

Author : Claudio Galli,Giovanni Galli,Giuseppe Porcellati
Publisher : Lippincott Williams & Wilkins
Page : 232 pages
File Size : 52,8 Mb
Release : 1978
Category : Medical
ISBN : WISC:89017574021

Get Book

Phospholipases and Prostaglandins by Claudio Galli,Giovanni Galli,Giuseppe Porcellati Pdf

Author : Ana Gil De Bona,Jose Antonio Reales-Calderon
Publisher : BoD – Books on Demand
Page : 172 pages
File Size : 54,9 Mb
Release : 2020-03-04
Category : Science
ISBN : 9781789239430

Get Book

Extracellular Vesicles and Their Importance in Human Health by Ana Gil De Bona,Jose Antonio Reales-Calderon Pdf

Extracellular vesicle is a wide term that involves many different types of vesicles. Almost all the cell types studied secrete vesicles to the extracellular environment related to cell - cell communication. Extracellular vesicles have been found in different biological fluids, such as blood, milk, saliva, tears, urine, and cerebrospinal fluid. These vesicles transport different molecules, including mRNA, proteins, and lipids, some of them cell type specific that make them ideal biomarkers in both health and disease conditions. However, their contribution to different conditions is not well understood. The aim of this book is to provide an overview of the extracellular vesicles in the human body, how they are internalized, and their participation in several diseases.

Author : Masaki Ieda,Wolfram-Hubertus Zimmermann
Publisher : Springer
Page : 274 pages
File Size : 40,6 Mb
Release : 2017-10-27
Category : Medical
ISBN : 9783319561066

Get Book

Cardiac Regeneration by Masaki Ieda,Wolfram-Hubertus Zimmermann Pdf

This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.

Author : Junjie Xiao
Publisher : Springer
Page : 387 pages
File Size : 55,8 Mb
Release : 2017-11-02
Category : Medical
ISBN : 9789811043048

Get Book

Exercise for Cardiovascular Disease Prevention and Treatment by Junjie Xiao Pdf

The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice. The volume firstly summarizes the acute and chronic response to exercise. Secondly, evidence for exercise as medicine for the heart based on clinical studies and basic research is summarized. Thirdly, molecular mechanisms mediating the beneficial effects of exercise including IGF-1-PI3K-AKT signalling, NO signalling, C/EBPB-Cited4 signalling, Non-coding RNAs, epigenetic regulators, mitochondria adaption and exosomes are presented. Finally, exercise dosing, prescription and future prospects are provided. This book will provide valuable reference for researchers in cell biology, physiology, as well as physician, physical therapist in cardiology, sport medicine, etc.

Author : Paul Harrison,Chris Gardiner,Ian L. Sargent
Publisher : CRC Press
Page : 484 pages
File Size : 50,7 Mb
Release : 2014-05-02
Category : Medical
ISBN : 9789814411981

Get Book

Extracellular Vesicles in Health and Disease by Paul Harrison,Chris Gardiner,Ian L. Sargent Pdf

Interest in the role of extracellular vesicles (microvesicles and exosomes) is expanding rapidly. It is now apparent that far from being merely cellular debris, these vesicles play a key role in cell-to-cell communication and signaling. Moreover, they are significantly elevated in a number of diseases. This raises the question of their direct role in pathogenesis as well as their possible use as biomarkers. This book stems from the first international meeting on "Microvesicles and Nanovesicles in Health and Disease" held at Magdalen College, Oxford, in 2010. The purpose of the meeting was to bring together, for the first time, a range of experts from around the world to discuss the latest advances in this field. Key to the study of these vesicles is the availability of methodologies for their measurement in biological fluids. A major section of the meeting focused on a range of exciting new technologies which have been developed for this purpose. The presentations at this meeting form the basis of this book, which will appeal to basic scientists, clinicians, and those developing technology for the measurement of extracellular vesicles.

Author : Toshio Nakanishi,H. Scott Baldwin,Jeffrey R. Fineman,Hiroyuki Yamagishi
Publisher : Springer Nature
Page : 374 pages
File Size : 44,6 Mb
Release : 2020-02-28
Category : Medical
ISBN : 9789811511851

Get Book

Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension by Toshio Nakanishi,H. Scott Baldwin,Jeffrey R. Fineman,Hiroyuki Yamagishi Pdf

This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.

Author : Haisheng Yang
Publisher : BoD – Books on Demand
Page : 143 pages
File Size : 48,9 Mb
Release : 2019-04-24
Category : Medical
ISBN : 9781789857672

Get Book

Osteogenesis and Bone Regeneration by Haisheng Yang Pdf

Osteogenesis is a core component of the skeletal system and depends on the well-coordinated proliferation and differentiation of osteogenic cells. Multiple signaling pathways and transcriptional factors tightly regulate the process of osteogenesis. Any abnormities in bone formation could cause severe disorders such as osteogenesis imperfecta and osteoporosis. Bone regeneration, a complex and well-orchestrated physiological process of osteogenesis, remains a medical challenge in the field of orthopedics and maxillofacial surgery. This book provides an overview of the current developments in osteogenesis and bone regeneration, including molecular and cellular mechanisms, physical therapies (low-level laser, distraction osteogenesis), biological therapies (mesenchymal stem cells, stem cell derived exosomes, inflammatory factor, Chinese medicine), as well as tissue engineering approaches promoting bone regeneration by targeting osteogenesis.

Author : Mohamed Boutjdir,Pietro Enea Lazzerini,Robert Murray Hamilton
Publisher : Frontiers Media SA
Page : 263 pages
File Size : 44,5 Mb
Release : 2020-01-30
Category : Electronic
ISBN : 9782889633975

Get Book

 Cardioimmunology: Inflammation and Immunity in Cardiovascular Disease by Mohamed Boutjdir,Pietro Enea Lazzerini,Robert Murray Hamilton Pdf