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Author : Menon, Devidas,Canadian Coordinating Office for Health Technology Assessment
Publisher : Unknown
Page : 41 pages
File Size : 44,7 Mb
Release : 1991
Category : Pulmonary surfactant
ISBN : 189556106X
Author : Burkhard Lachmann
Publisher : Springer Science & Business Media
Page : 389 pages
File Size : 47,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642733055
I am very happy and honoured to have so many famous contrib utors from around the world presenting their knowledge and experience in this book, including Dr. Rufer who, as early as 1967, attempted to improve the pressure-volume curve of a child dying from RDS using dried surfactant from dogs; Drs. Enhorn ing and Robertson who were the first to treat rabbit fetuses with surfactant replacement and impressively demonstrated that sur factant improved lung mechanics; and Dr. Fujiwara who at the end of the 1970's had already successfully treated the first babies with surfactant replacement and published this work al ready in 1980. Thus, the idea of surfactant replacement therapy is now more or less 20 years old and almost 10 years have passed since the first publication by Dr. Fujiwara of his impressive clinical results. Up to now (September, 1988) about 2,200 babies have been treated worldwide with tracheal instillation of surfactant, with most promising results. The type of surfactant used varies from pure natural extracts from bovine or pig lungs, to surfactant extracted from human amniotic fluid, to pure phospholipids. To date, however, there is still no surfactant commercially available (except in Japan), in spite of the fact that it is urgently awaited by neonatologists and intensive care doctors throughout the world. This volume is based on the contributions presented at the international congress on Surfactant Replacement Therapy which was held in Rotterdam, The Netherlands, in November 1987.
Author : Donald L. Shapiro,Robert H. Notter
Publisher : Alan R. Liss
Page : 344 pages
File Size : 47,9 Mb
Release : 1989
Category : Medical
ISBN : UOM:39015014473956
Author : John C. Sinclair,Michael B. Bracken
Publisher : Unknown
Page : 714 pages
File Size : 42,7 Mb
Release : 1992
Category : Medical
ISBN : UOM:39015020874361
This companion volume to the highly acclaimed Effective Care in Pregnancy and Childbirth (OUP 1989, edited by Iain Chalmers et al.) evaluates the care of newborn infants. Medical research has produced an explosion of new knowledge concerning the causes, diagnosis, prognosis, treatment and prevention of diseases of the newborn infant. As the pace of therapeutic innovation quickens, there is an increasing need for efficient access to information concerning the probable effects of therapy. This book meets the urgent demand for a systematic summary of the best available evidence concerning the expected outcomes of therapeutic decisions in neonatology. This revolutionary work consists fundamentally of quantitative reviews of randomized trials of alternative courses of action. It contains some 2000 new analyses of data from the clinical trials literature, representing the vast majority of randomized trials in neonatology. The result is the first systematic review of evidence from randomized clinical trials in this field and an explicit dissection of the research data supporting, or in some cases not supporting, clinical management of the newborn. This book will interest pediatricians, especially neonatologists; obstetricians, especially maternal-fetal medicine specialists; family practitioners; and epidemiologists.
Author : Egbert Herting,Wieland Kiess
Publisher : S. Karger AG (Switzerland)
Page : 0 pages
File Size : 55,5 Mb
Release : 2020
Category : Neonatology
ISBN : 3318066206
Innovations and Frontiers in Neonatology provides up-to-date information for clinicians and scientists interested in perinatal medicine. Neonatal transition, neonatal medicine from a global perspective, aspects of care including nutrition, respiratory and temperature management, resuscitation, family-centered approaches, and problems of the term newborn are covered as are complications and long-term consequences of preterm birth. Should we ventilate and how? What are the lifelong consequences of being born too small? How can we protect the neonatal brain? Can we actively influence the microbiome? Can we achieve individualized medicine with the help of metabolomics, for example? Are stem cells the miracle cure? These are just a few of the questions that world experts cover in this book while, at the same time, they take a look at the future of neonatal medicine.
Author : Peter C. Rimensberger
Publisher : Springer
Page : 1642 pages
File Size : 40,5 Mb
Release : 2014-11-12
Category : Medical
ISBN : 9783642012198
Written by outstanding authorities from all over the world, this comprehensive new textbook on pediatric and neonatal ventilation puts the focus on the effective delivery of respiratory support to children, infants and newborns. In the early chapters, developmental issues concerning the respiratory system are considered, physiological and mechanical principles are introduced and airway management and conventional and alternative ventilation techniques are discussed. Thereafter, the rational use of mechanical ventilation in various pediatric and neonatal pathologies is explained, with the emphasis on a practical step-by-step approach. Respiratory monitoring and safety issues in ventilated patients are considered in detail, and many other topics of interest to the bedside clinician are covered, including the ethics of withdrawal of respiratory support and educational issues. Throughout, the text is complemented by numerous illustrations and key information is clearly summarized in tables and lists.
Author : Menon, Devidas,Canadian Coordinating Office for Health Technology Assessment,Office canadien de coordination de l'évaluation des technologies de la santé
Publisher : Office canadien de coordination de l'évaluation des technologies de la santé
Page : 41 pages
File Size : 40,7 Mb
Release : 1991
Category : Infants Diseases
ISBN : 1895561108
Author : Mark W. Davies,David W. Cartwright
Publisher : Elsevier Australia
Page : 194 pages
File Size : 53,6 Mb
Release : 2008
Category : Medical
ISBN : 9780729538329
This little pocket guide has been designed as a ready reference to guide junior medical officers and nursing staff who care for infants admitted to intensive and special care.
Author : Stavros Kassinos,Per Bäckman,Joy Conway,Anthony J. J. Hickey
Publisher : Academic Press
Page : 439 pages
File Size : 49,5 Mb
Release : 2021-01-20
Category : Business & Economics
ISBN : 9780128149751
Inhaled medicines are widely used to treat pulmonary and systemic diseases. The efficacy and safety of these medicines can be influenced by the deposited fraction, the regional deposition pattern within the lungs and by post-depositional events such as drug dissolution, absorption and clearance from the lungs. Optimizing performance of treatments thus requires that we understand and are able to quantify these product and drug attributes. Inhaled Medicines: Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches explores the current state of the art with respect to inhalation drug delivery, technologies available to assess product performance, and novel in silico methods now available to link in vitro product performance to clinical performance. Recent developments in the latter field, especially the prospect of integration of three-dimensional Computational Fluid Particle Methods (3D-CFPD) with physiologically based pharmacokinetic (PBPK models), unlocks the potential for in silico population studies that can help inform and optimize treatment and product development strategies. In this highly multidisciplinary field, where progress occurs at the intersection of several disciplines of engineering and science, this work aims to integrate current knowledge and understanding and to articulate a clear vision for future developments. Considers the healthcare needs driving the field, and where inhaled drugs could have the maximum impact Gives a concise account of the state of the art in key areas and technologies such as device and formulation technologies, clinically relevant in vitro performance assessment, medical imaging, as well as in silico modelling and simulation Articulates how the combination of in vitro product performance data, medical imaging and simulations technologies in the framework of large scale in silico pre-clinical trials could revolutionize the field Provides systematic and thorough referencing to sources offering a more-in-depth analysis of technical issues
Author : Committee on Damp Indoor Spaces and Health
Publisher : National Academies Press
Page : 368 pages
File Size : 40,7 Mb
Release : 2004-08-31
Category : Medical
ISBN : 9780309133395
Almost all homes, apartments, and commercial buildings will experience leaks, flooding, or other forms of excessive indoor dampness at some point. Not only is excessive dampness a health problem by itself, it also contributes to several other potentially problematic types of situations. Molds and other microbial agents favor damp indoor environments, and excess moisture may initiate the release of chemical emissions from damaged building materials and furnishings. This new book from the Institute of Medicine examines the health impact of exposures resulting from damp indoor environments and offers recommendations for public health interventions. Damp Indoor Spaces and Health covers a broad range of topics. The book not only examines the relationship between damp or moldy indoor environments and adverse health outcomes but also discusses how and where buildings get wet, how dampness influences microbial growth and chemical emissions, ways to prevent and remediate dampness, and elements of a public health response to the issues. A comprehensive literature review finds sufficient evidence of an association between damp indoor environments and some upper respiratory tract symptoms, coughing, wheezing, and asthma symptoms in sensitized persons. This important book will be of interest to a wide-ranging audience of science, health, engineering, and building professionals, government officials, and members of the public.
Author : Mohamed E. A. Abdelrahim,Haitham Saeed,Hadeer S. Harb,Yasmin M. Madney
Publisher : Springer Nature
Page : 245 pages
File Size : 49,7 Mb
Release : 2021-10-21
Category : Medical
ISBN : 9783030850265
This book assesses the most appropriate forms of aerosol therapy for critically ill patients. Aerosol therapy is applied for the treatment of several pulmonary diseases in addition to some promising applications intended for systemic absorption. Nowadays, aerosol delivery to clinically stable patients in the outpatient settings is done easily with a lot of focus on patient counseling and enhancement of lung deposition. A lot of guidelines are available for several diseases and it could offer adequate guidance to the therapists concerning escalation or de-escalation of therapy to enhance treatment efficiency and safety. However, in critically ill patients aerosol delivery is mostly done by the choice of the respiratory therapist only according to his knowledge. The book describes the type of patients requiring aerosol therapy, different aerosol generators available for the treatment of critically ill patients, mechanisms of aerosol lung deposition, and factors affecting aerosol deposition. It also discusses the special needs of neonates and infants, transitioning aerosol from hospital to home, and the methods of aerosol delivery to different patient e.g. nasal delivery patients, ventilated patients, etc. Moreover, it reviews methods of detecting such aerosol delivery to the lung. At the end, it discusses the suggested monitoring plans and weaning protocols to ensure high efficacy and safety of the ventilatory support in such patients. Given its scope, the book can serve as guidelines or specific recommendations to maximize clinical benefits of medicated aerosols in critically ill patients and it represents a valuable resource for intensivists, pulmonologists and healthcare professionals working at ICUs.
Author : M. R. Khan
Publisher : Elsevier India
Page : 561 pages
File Size : 43,7 Mb
Release : 2011-08-10
Category : Medical
ISBN : 9788131228043
From their vast knowledge and experience, authors bring the essence of the subject "pediatrics" in the form of this text book, which will serve the purpose for students (both undergraduate and postgraduates), teachers and practicing pediatricians. Covers all common pediatric problems prevailing in the Indian sub-continent in lucid and easy-to-understand language. Concise, contains the recent updates, more community oriented, edited more frequently, less voluminous. Written by well-experienced eminent authors, who are serving as Professors and Consultants, facing day-to-day challenges of the subject. Designed as a textbook for both undergraduate and postgraduate students and as a guide to the teachers of pediatrics and practicing pediatricians. Chapters like Neonatology, Infant Feeding, Growth and Development, Neurology, Oncology, Connective Tissue Diseases, and Immunization have been revised completely; and topics like Nephrotic Syndrome, Diabetes Mellitus, Newer Vaccines, Infectious Diseases, Genetic Disorders, Neurometabolic and Seizure Disorders have been updated extensively. New chapter, 'Drug Therapy', has been added; all critical emergency information, including shock, resuscitation, and life-threatening conditions are discussed duly. Management of common pediatric problems has been written following most recent WHO guidelines.
Author : Derek S. Wheeler,Hector R. Wong,Thomas P. Shanley
Publisher : Springer Science & Business Media
Page : 254 pages
File Size : 51,8 Mb
Release : 2008-12-18
Category : Medical
ISBN : 9781848009257
The principal role of the respiratory system is to permit ef? cient exchange of respiratory gases (O and CO ) with the environment. The respiratory system is unique in that it is constantly 2 2 exposed to a barrage of foreign substances from both the internal environment (at any one point in time, approximately one-half of the cardiac output is received by the lungs) and the external environment (with each breath, the respiratory tract is exposed to pollens, viruses, bacteria, smoke, etc). According to the Centers for Disease Control and Prevention, diseases of the res- ratory system were the seventh and eighth leading causes of deaths in children aged 1 to 19 years in 2003 [1]. Dr. George A. Gregory, one of the founding fathers of pediatric critical care me- cine, once estimated that acute respiratory failure accounts for nearly 50% of all admissions to the pediatric intensive care unit (PICU) [2]. Just as important are the many diseases that affect the respiratory system that are not associated with acute respiratory failure, but nevertheless constitute a major portion of the practice of pediatric critical care medicine, some of which account for signi? cant morbidity and mortality [3]. Once again, we would like to dedicate this textbook to our families and to the physicians and nurses who provide steadfast care every day in pediatric intensive care units across the globe. Derek S. Wheeler Hector R. Wong Thomas P.
Author : Pilar Garcia-Peña,R. Paul Guillerman
Publisher : Springer
Page : 545 pages
File Size : 49,5 Mb
Release : 2014-08-09
Category : Medical
ISBN : 9783642373374
Since the second edition of Pediatric Chest Imaging was published in 2007, there have been further significant advances in our understanding of chest diseases and continued development of new imaging technology and techniques. The third, revised edition of this highly respected reference publication has been thoroughly updated to reflect this progress. Due attention is paid to the increased role of hybrid imaging, and entirely new chapters cover topics such as interventional radiology, lung MRI, functional MRI, diffuse/interstitial lung disease, and cystic fibrosis. As in previous editions, the focus is on technical aspects of modern imaging modalities, their indications in pediatric chest disease, and the diagnostic information that they supply. Pediatric Chest Imaging will be an essential asset for pediatricians, neonatologists, cardiologists, radiologists, and pediatric radiologists everywhere.
Author : Robert H. Notter
Publisher : CRC Press
Page : 476 pages
File Size : 45,5 Mb
Release : 2000-07-18
Category : Science
ISBN : 0824704010
Integrating basic and clinical research on the biophysical and physiological functions of pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on surfactant-related lung disease. Manage neonatal respiratory distress syndrome (RDS), acute respiratory distress syndrome (ARDS), and acute lung injury more effectively!