Flow Chemistry

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Continuous-Flow Chemistry in the Research Laboratory

Author : Toma Glasnov
Publisher : Springer
Page : 119 pages
File Size : 49,8 Mb
Release : 2016-06-01
Category : Science
ISBN : 9783319321967

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Continuous-Flow Chemistry in the Research Laboratory by Toma Glasnov Pdf

This book presents a short introduction to the historical background to the field, the state of the art and a brief survey of the available instrumentation and the processing techniques used. The following major areas of interest in synthetic, organic and medicinal chemistry are elaborated on: transition-metal catalyzed reactions, organocatalytic transformations, heterocyclic synthesis, and photochemical reactions. Finally, selected applications in industry are also discussed. With its ample presentation of examples from recent literature, this is an essential and reliable source of information for both experienced researchers and postgraduate newcomers to the field.

Fundamentals

Author : Ferenc Darvas,Volker Hessel,György Dorman
Publisher : Walter de Gruyter GmbH & Co KG
Page : 313 pages
File Size : 52,8 Mb
Release : 2014-08-25
Category : Technology & Engineering
ISBN : 9783110388756

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Fundamentals by Ferenc Darvas,Volker Hessel,György Dorman Pdf

"Flow Chemistry fills the gap in graduate education by covering chemistry and reaction principles along with current practice, including examples of relevant commercial reaction, separation, automation, and analytical equipment. The Editors of Flow Chemistry are commended for having taken the initiative to bring together experts from the field to provide a comprehensive treatment of fundamental and practical considerations underlying flow chemistry. It promises to become a useful study text and as well as reference for the graduate students and practitioners of flow chemistry." Professor Klavs Jensen Massachusetts Institute of Technology, USA Broader theoretical insight in driving a chemical reaction automatically opens the window towards new technologies particularly to flow chemistry. This emerging concept promotes the transformation of present day's organic processes into a more rapid continuous set of synthesis operations, more compatible with the envisioned sustainable world. These two volumes Fundamentals and Applications provide both the theoretical foundation as well as the practical aspects.

Applications

Author : Ferenc Darvas,Volker Hessel,György Dorman
Publisher : Walter de Gruyter GmbH & Co KG
Page : 370 pages
File Size : 44,7 Mb
Release : 2014-11-18
Category : Technology & Engineering
ISBN : 9783110367508

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Applications by Ferenc Darvas,Volker Hessel,György Dorman Pdf

"Flow Chemistry fills the gap in graduate education by covering chemistry and reaction principles along with current practice, including examples of relevant commercial reaction, separation, automation, and analytical equipment. The Editors of Flow Chemistry are commended for having taken the initiative to bring together experts from the field to provide a comprehensive treatment of fundamental and practical considerations underlying flow chemistry. It promises to become a useful study text and as well as reference for the graduate students and practitioners of flow chemistry." Professor Klavs Jensen Massachusetts Institute of Technology, USA Broader theoretical insight in driving a chemical reaction automatically opens the window towards new technologies particularly to flow chemistry. This emerging concept promotes the transformation of present day's organic processes into a more rapid continuous set of synthesis operations, more compatible with the envisioned sustainable world. These two volumes Fundamentals and Applications provide both the theoretical foundation as well as the practical aspects.

Flow Chemistry in Drug Discovery

Author : Jesus Alcazar,Antonio de la Hoz,Angel Díaz-Ortiz
Publisher : Springer Nature
Page : 501 pages
File Size : 45,8 Mb
Release : 2021-12-08
Category : Science
ISBN : 9783030855925

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Flow Chemistry in Drug Discovery by Jesus Alcazar,Antonio de la Hoz,Angel Díaz-Ortiz Pdf

This book reviews the challenges and opportunities posed by flow chemistry in drug discovery, and offers a handy reference tool for medicinal chemists interested in the synthesis of biologically active compounds. Prepared by expert contributors, the respective chapters cover not only fundamental methodologies and reactions, such as the application of catalysis, especially biocatalysis and organocatalysis; and non-conventional activation techniques, from photochemistry to electrochemistry; but also the development of new process windows, processes and reactions in drug synthesis. Particular attention is given to automatization and library synthesis, which are of great importance in the pharmaceutical industry. Readers will also find coverage on selected topics of general interest, such as how flow chemistry is contributing to drug discovery R&D in developing countries, and the green character of this enabling technology, for example in the production of raw materials for the pharmaceutical industry from waste. Given its scope, the book appeals to medicinal chemistry researchers working in academia and industry alike, as well as professionals involved in scale-up and drug development.

Electron Flow in Organic Chemistry

Author : Paul H. Scudder
Publisher : John Wiley & Sons
Page : 448 pages
File Size : 48,7 Mb
Release : 2013-01-09
Category : Science
ISBN : 9780470638040

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Electron Flow in Organic Chemistry by Paul H. Scudder Pdf

Sets forth the analytical tools needed to solve key problems in organic chemistry With its acclaimed decision-based approach, Electron Flow in Organic Chemistry enables readers to develop the essential critical thinking skills needed to analyze and solve problems in organic chemistry, from the simple to complex. The author breaks down common mechanistic organic processes into their basic units to explain the core electron flow pathways that underlie these processes. Moreover, the text stresses the use of analytical tools such as flow charts, correlation matrices, and energy surfaces to enable readers new to organic chemistry to grasp the fundamentals at a much deeper level. This Second Edition of Electron Flow in Organic Chemistry has been thoroughly revised, reorganized, and streamlined in response to feedback from both students and instructors. Readers will find more flowcharts, correlation matrices, and algorithms that illustrate key decision-making processes step by step. There are new examples from the field of biochemistry, making the text more relevant to a broader range of readers in chemistry, biology, and medicine. This edition also offers three new chapters: Proton transfer and the principles of stability Important reaction archetypes Qualitative molecular orbital theory and pericyclic reactions The text's appendix features a variety of helpful tools, including a general bibliography, quick-reference charts and tables, pathway summaries, and a major decisions guide. With its emphasis on logical processes rather than memorization to solve mechanistic problems, this text gives readers a solid foundation to approach and solve any problem in organic chemistry.

Flow Chemistry – Fundamentals

Author : Ferenc Darvas,György Dormán,Volker Hessel,Steven V. Ley
Publisher : Walter de Gruyter GmbH & Co KG
Page : 448 pages
File Size : 49,6 Mb
Release : 2021-10-25
Category : Technology & Engineering
ISBN : 9783110693676

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Flow Chemistry – Fundamentals by Ferenc Darvas,György Dormán,Volker Hessel,Steven V. Ley Pdf

The fully up-dated edition of the two-volume work covers both the theoretical foundation as well as the practical aspects. Presenting the complete insight into driving a chemical reaction provides a deep understanding for new potential technologies. Updated overview on devices and new key concepts of experimental procedures. Vol. 2: Applications.

Flow Chemistry – Applications

Author : Ferenc Darvas,György Dormán,Volker Hessel,Steven V. Ley
Publisher : Walter de Gruyter GmbH & Co KG
Page : 376 pages
File Size : 54,9 Mb
Release : 2021-10-25
Category : Technology & Engineering
ISBN : 9783110693690

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Flow Chemistry – Applications by Ferenc Darvas,György Dormán,Volker Hessel,Steven V. Ley Pdf

The fully up-dated edition of the two-volume work covers both the theoretical foundation as well as the practical aspects. A strong insight in driving a chemical reaction is crucial for a deeper understanding of new potential technologies. New procedures for warranty of safety and green principles are discussed. Vol. 1: Fundamentals.

Flow Chemistry – Fundamentals

Author : Ferenc Darvas,György Dormán,Volker Hessel,Steven V. Ley
Publisher : Walter de Gruyter GmbH & Co KG
Page : 568 pages
File Size : 41,6 Mb
Release : 2021-10-25
Category : Technology & Engineering
ISBN : 9783110693775

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Flow Chemistry – Fundamentals by Ferenc Darvas,György Dormán,Volker Hessel,Steven V. Ley Pdf

The fully up-dated edition of the two-volume work covers both the theoretical foundation as well as the practical aspects. Presenting the complete insight into driving a chemical reaction provides a deep understanding for new potential technologies. Updated overview on devices and new key concepts of experimental procedures. Vol. 2: Applications.

Flow Chemistry

Author : Santiago V Luis,Eduardo Garcia-Verdugo
Publisher : Royal Society of Chemistry
Page : 560 pages
File Size : 53,8 Mb
Release : 2019-09-18
Category : Science
ISBN : 9781788018937

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Flow Chemistry by Santiago V Luis,Eduardo Garcia-Verdugo Pdf

Historically pharmaceutical and fine chemical products have been synthesised using batch methods, but increasingly chemists are looking towards flow chemistry as a greener and more efficient alternative. In flow chemistry reactions are performed in a reactor with the reactants pumped through it. It has the benefit of being easily scaled up and it is straightforward to integrate synthesis, workup and analysis into one system. Flow chemistry is considered a greener alternative to batch chemistry because it is easier to control and minimise hazardous intermediates and by-products. There is significant interest in the use of flow chemistry both in the lab and on an industrial scale. Flow Chemistry provides an update on recent advances that have been made in the field. Particular emphasis is given to the new integrated approaches that bring together several elements to implement flow processes as a regular green chemistry tool for the chemical industries. With chapter contributions from several well-known experts in the field, this book is a valuable resource for researchers working in green chemistry and synthesis, chemical engineers and industrial chemists working in the pharmaceutical and fine chemicals industries.

Organometallic Flow Chemistry

Author : Timothy Noël
Publisher : Springer
Page : 267 pages
File Size : 50,5 Mb
Release : 2016-04-22
Category : Science
ISBN : 9783319332437

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Organometallic Flow Chemistry by Timothy Noël Pdf

The series Topics in Organometallic Chemistry presents critical overviews of research results in organometallic chemistry. As our understanding of organometallic structure, properties and mechanisms increases, new ways are opened for the design of organometallic compounds and reactions tailored to the needs of such diverse areas as organic synthesis, medical research, biology and materials science. Thus the scope of coverage includes a broad range of topics of pure and applied organometallic chemistry, where new breakthroughs are being achieved that are of significance to a larger scientific audience. The individual volumes of Topics in Organometallic Chemistry are thematic. Review articles are generally invited by the volume editors. All chapters from Topics in Organometallic Chemistry are published OnlineFirst with an individual DOI. In references, Topics in Organometallic Chemistry is abbreviated as Top Organomet Chem and cited as a journal

Sustainable Flow Chemistry

Author : Luigi Vaccaro
Publisher : John Wiley & Sons
Page : 336 pages
File Size : 51,7 Mb
Release : 2017-03-14
Category : Science
ISBN : 9783527689088

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Sustainable Flow Chemistry by Luigi Vaccaro Pdf

This ready reference not only presents the hot and emerging topic of modern flow chemistry, it is also unique in illustrating the important connection to sustainable chemistry. Focusing on more sustainable methods and applications, the text extensively covers every important field from reaction time optimization to waste minimization, and from safety improvements to microwave applications. In addition, green metrics are presented as a key aspect of the book, helping readers to evaluate the efficiency of flow technologies and their impact on the overall efficiency of a chemical process. An invaluable handbook for every chemist working in the laboratory, whether in academia or industry.

Flow Chemistry

Author : Santiago V Luis,Eduardo Garcia-Verdugo
Publisher : Royal Society of Chemistry
Page : 560 pages
File Size : 41,5 Mb
Release : 2019-10-18
Category : Science
ISBN : 9781788014984

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Flow Chemistry by Santiago V Luis,Eduardo Garcia-Verdugo Pdf

In flow chemistry reactions are performed in a reactor with the reactants pumped through it. It has the benefit of being easily scaled up and it is straightforward to integrate synthesis, workup and analysis into one system. This volume provides an update on recent advances in the field of flow chemistry, with special emphasis on new, integrated approaches for green and efficient chemistry. This book is a valuable resource for researchers in green chemistry, chemical engineers and Industrial chemists working in the pharmaceutical and fine chemicals industries.

Flash Chemistry

Author : Jun-ichi Yoshida
Publisher : John Wiley & Sons
Page : 244 pages
File Size : 43,5 Mb
Release : 2008-10-13
Category : Science
ISBN : 9780470723418

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Flash Chemistry by Jun-ichi Yoshida Pdf

Have you ever wished you could speed up your organic syntheses without losing control of the reaction? Flash Chemistry is a new concept which offers an integrated scheme for fast, controlled organic synthesis. It brings together the generation of highly reactive species and their reactions in Microsystems to enable highly controlled organic syntheses on a preparative scale in timescales of a few seconds or less. Flash Chemistry: Fast Organic Synthesis in microsystems is the first book to describe this exciting new technique, with chapters covering: an introduction to flash chemistry reaction dynamics: how fast is the act of chemical transformation, what is the rate of reaction, and what determines the selectivity of a reaction? examples of why flash chemistry is needed: the rapid construction of chemical libraries, rapid synthesis of radioactive PET probes, and on-demand rapid synthesis in industry the generation of highly reactive species through thermal, microwave, chemical, photochemical, and electrochemical activation microsystems: What are microsystems and how are they made? Why is size so important? What are the characteristic features of microsystems? conduction and control of extremely fast reactions using microsystems applications of flash chemistry in organic synthesis polymer synthesis based on flash chemistry industrial applications of flash chemistry Flash Chemistry: Fast Organic Synthesis in Microsystems is an essential introduction to anyone working in organic synthesis, process chemistry, chemical engineering and physical organic chemistry concerned with fundamental aspects of chemical reactions an d synthesis and the production of organic compounds.

Science of Synthesis: Flow Chemistry in Organic Synthesis

Author : T.F. Jamison,G. Koch
Publisher : Thieme
Page : 932 pages
File Size : 44,9 Mb
Release : 2018-12-12
Category : Science
ISBN : 9783132423343

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Science of Synthesis: Flow Chemistry in Organic Synthesis by T.F. Jamison,G. Koch Pdf

The aim of this work is to convey the practice, power, and potential of flow chemistry to a larger audience. An emerging and strengthening trend is that flow chemistry is much more than the adaption of batch processes to flow systems. Rather, flow chemistry offers a new paradigm in the way we think about chemical synthesis. This volume demonstrates the enabling power of continuous flow to access new reaction types and different chemistry space and, to this end, it has been compiled by a team of pioneers and leaders, who present both the practical and conceptual aspects of this rapidly growing field. Included are the principles of reactor design, automation, and separations/purifications in flow systems, applications in photochemistry, electrochemistry, gaseous systems, immobilized reagents and catalysts, and multistep processes. The synthesis of peptides, carbohydrates, and pharmaceuticals is covered and several chapters give insight into the use of flow in an industrial context.

Accounts on Sustainable Flow Chemistry

Author : Timothy Noël,Rafael Luque
Publisher : Springer Nature
Page : 190 pages
File Size : 48,5 Mb
Release : 2020-01-23
Category : Science
ISBN : 9783030365721

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Accounts on Sustainable Flow Chemistry by Timothy Noël,Rafael Luque Pdf

The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.