Flow Cytometry In Evaluation Of Hematopoietic Neoplasms

Author : Sindhu Cherian,Brent Wood
Publisher : Unknown
Page : 165 pages
File Size : 42,6 Mb
Release : 2012
Category : Medical
ISBN : 0983706824

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Flow Cytometry in Evaluation of Hematopoietic Neoplasms by Sindhu Cherian,Brent Wood Pdf

Flow Cytometry in Evaluation of Hematopoietic Neoplasms: A Case-Based Approach is a practical, case-based guide to flow cytometric analysis in the workup of hematopoietic neoplasms presenting in the peripheral blood, marrow, lymphoid tissue, and extranodal sites. Using multi-color techniques pioneered by Brent Wood, the text demonstrates a unique approach to diagnosis of hematopoietic malignancies as well as identification of small abnormal populations in the posttherapy setting (minimal residual disease testing). The publication contains an introduction to immunophenotypic changes seen in normal hematopoiesis along with an overview of the evaluation of lymphomas, leukemias, and myeloid stem- cell neoplasms. These concepts are further illustrated by a series of 36 cases, each dedicated to a specific disease entity. Each case provides detailed, full-color images of flow cytometric dot plots that clearly outline the features of the disease, accompanied by a clinical history and thorough discussion, enabling readers to develop and work through a differential diagnosis and recognize potential diagnostic pitfalls. Take-home points for each case emphasize critical concepts in flow cytometric diagnosis. Flow Cytometry in Evaluation of Hematopoietic Neoplasms provides pathologists, residents, laboratory technologists, and hematologists with both a study guide and an atlas for regular consultation in the clinical flow cytometry laboratory. The 2008 World Health Organization (WHO) classification system, French-American-British (FAB) classifications, and 2006 Bethesda Consensus recommendations are incorporated in the text.

Author : David M. Dorfman
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 45,5 Mb
Release : 2017-11-19
Category : Medical
ISBN : 9780323552837

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Flow Cytometry, An Issue of Clinics in Laboratory Medicine, E-Book by David M. Dorfman Pdf

This issue of Clinics in Laboratory Medicine, edited by David M. Dorfman, will cover Flow Cytometry. Topics covered in this issue include: Flow cytometric evaluation of primary immunodeficiencies; Flow cytometry of B cell neoplasms; Flow cytometry of T cell neoplasms; Flow cytometry of acute myeloid leukemias; AML minimal residual disease (MRD) assessment by flow cytometric analysis; Acute lymphoblastic leukemia minimal residual disease (MRD) assessment by flow cytometric analysis; Flow cytometric assessment of myelodysplasia and myeloproliferative neoplasms; Flow cytometry of plasma cell neoplasms, including MRD testing; Paroxysmal nocturnal hemoglobinuria (PNH) assessment by flow cytometric analysis; Mast cell disease assessment by flow cytometric analysis; Flow cytometry in pediatric hematopathology; Clinical applications of mass cytometry; Automated analysis of clinical flow cytometry data; and Cost-effective flow cytometric testing strategies.

Author : Tsieh Sun
Publisher : Lippincott Williams & Wilkins
Page : 449 pages
File Size : 41,8 Mb
Release : 2012-01-19
Category : Medical
ISBN : 9781451180640

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Flow Cytometry, Immunohistochemistry, and Molecular Genetics for Hematologic Neoplasms by Tsieh Sun Pdf

Immunophenotyping is the most powerful tool in the routine diagnosis of hematologic neoplasms. Immunohistochemical technique is used in histology labs for this purpose, while flow cytometry is used in clinical labs. Although separately these 2 techniques are very useful in detecting lymphomas and leukemias, the combination of both creates a very powerful and definitive diagnostic tool. The addition of molecular genetics to the book makes it an all-encompassing reference text.

Author : Claudio Ortolani
Publisher : John Wiley & Sons
Page : 464 pages
File Size : 46,7 Mb
Release : 2021-04-19
Category : Medical
ISBN : 9781119611271

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Flow Cytometry of Hematological Malignancies by Claudio Ortolani Pdf

Flow Cytometry of Hematological Malignancies Flow cytometric analysis is often integral to the swift and accurate diagnosis of leukemias and lymphomas of the blood, bone marrow, and lymph nodes. However, in the fast-moving and expanding field of clinical hematology, in can be challenging to remain up to speed with the latest biological research and technological innovations. Flow Cytometry of Hematological Malignancies has been designed to provide all those working in hematological oncology with a practical, cutting-edge handbook, featuring clear and fully illustrated guidance on all aspects of cytometry’s role in diagnosis and analysis. This essential second edition includes: Explorations of more than 70 antigens Full-color illustrations throughout New descriptions of recently discovered markers WHO classifications of hematological neoplastic diseases Helpful tips for result interpretation and analysis Featuring all this and more, Flow Cytometry of Hematological Malignancies, Second Edition, is an invaluable resource for both trainee and experienced hematologists, hematopathologists, oncologists, and pathologists, as well as medical students and diagnostic lab technicians.

Author : Wojciech Gorczyca
Publisher : CRC Press
Page : 350 pages
File Size : 54,7 Mb
Release : 2010-02-25
Category : Medical
ISBN : 9781841847443

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Flow Cytometry in Neoplastic Hematology by Wojciech Gorczyca Pdf

This highly illustrated, practical guide contains comprehensive coverage of all the important factors for clinical diagnosis with flow cytometry. It explains the general parameters and correlation with color histomorphological findings throughout, taking a systematic approach from basic cases to complicated problem areas. Hematopathologists and neoplastic hematologists will find this book an important resource for keeping up to date with developments in clinical practice. This second edition includes a chapter on antigen expression during myeloid and lymphoid differentiation.

Author : Anna Porwit,Marie Christine Béné
Publisher : Cambridge University Press
Page : 247 pages
File Size : 41,7 Mb
Release : 2018-01-25
Category : Medical
ISBN : 9781107503830

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Multiparameter Flow Cytometry in the Diagnosis of Hematologic Malignancies by Anna Porwit,Marie Christine Béné Pdf

This practical manual offers an active understanding of how to implement flow-cytometry when facing complex, haematological diseases.

Author : David F. Keren,J. Philip McCoy,John L. Carey
Publisher : American Society of Clinical Pathologists Press
Page : 764 pages
File Size : 47,6 Mb
Release : 2001
Category : Medical
ISBN : UOM:39015054271906

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Flow Cytometry in Clinical Diagnosis by David F. Keren,J. Philip McCoy,John L. Carey Pdf

Author : Stephen J. Withrow,Rodney Page,David M. Vail
Publisher : Elsevier Health Sciences
Page : 775 pages
File Size : 55,9 Mb
Release : 2012-11-13
Category : Medical
ISBN : 9781437723625

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Withrow and MacEwen's Small Animal Clinical Oncology by Stephen J. Withrow,Rodney Page,David M. Vail Pdf

With a unique focus on the most effective interventional techniques, Withrow & MacEwen's Small Animal Clinical Oncology, 5th Edition tells the full story of cancer in dogs and cats - what it is, how to diagnose it, and how to treat many of the most common cancers encountered in clinical practice. Nearly 500 color photographs, diagrams, x-rays, and gross views depict the clinical manifestations of various cancers. This edition covers the latest advances in clinical oncology, including chemotherapy, surgical oncology, and diagnostic techniques. With contributions from 65 veterinary oncology experts, this authoritative reference is a must-have for current, evidence-based therapeutic strategies on canine and feline oncology. "I really love this book. If you are interested in veterinary oncology, have a flick through this book online or at a conference when you get the chance. I hope that you agree with me that this is the definitive oncology reference source for the early 21st century and that you feel compelled to buy it. Your patients will thank you for it." Reviewed by: Gerry Polton MA VetMB MSc(Clin Onc) DipECVIM-CA(Onc) MRCVS, UK Date: July 2014 Cutting-edge information on the complications of cancer, pain management, and the latest treatment modalities prepares you to diagnose and treat pets with cancer rather than refer cases to a specialist. A consistent format for chapters on body system tumors includes coverage of incidence and risk factors, pathology, natural behavior of tumors, history and clinical signs, diagnostic techniques and workup, treatment options, and prognosis for specific malignancies. A systems approach to the diagnosis and management of cancer facilitates access to information about the many malignancies affecting small animal patients. Nearly 500 color images provide accurate depictions of specific diseases and procedures. Helpful drug formularies provide quick access to information on indications, toxicities, and recommended dosages for chemotherapeutic and analgesic drugs used in cancer treatment. Expert contributors provide in-depth coverage of the most current information in his or her respective specialty in veterinary oncology. Chemotherapy protocols are included when case studies prove clinical efficacy. Discussion of compassion and supportive care for the management of pain, nutritional needs, and grief includes methods for handling the pet's pain and nutritional complications as well as the pet owner's grief when treatment is not successful. Thoroughly UPDATED chapters cover the most recent changes in the clinical management of melanoma, mast cell tumors, tumors of the skeletal system, tumors of the endocrine system, tumors of the mammary gland, urinary cancers, nervous system cancers, lymphoma, and histiocytic diseases. NEW Clinical Trials and Developmental Therapeutics chapter discusses the various phases of clinical trials as well as current challenges and opportunities in oncology drug development. NEW! A focus on the best recommended treatment options highlights therapeutic strategies that have been vetted by veterinary oncology experts. NEW co-author Dr. Rodney L. Page adds his valuable perspective, expertise, and research experience.

Author : Ole Didrik Laerum,Ole Didrik Lærum,Robert Bjerknes
Publisher : Unknown
Page : 304 pages
File Size : 48,9 Mb
Release : 1992
Category : Blood
ISBN : UOM:39015029255331

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Flow Cytometry in Hematology by Ole Didrik Laerum,Ole Didrik Lærum,Robert Bjerknes Pdf

This book reviews flow cytometric methods (techniques for measuring and sorting of cells) used in hematology--ranging from those in routine use (such as leukocyte counting and immunophentotyping in diseases like leukemia and AIDS) to those that have potential future use in experimental and clinical hematology. This volume will be of interest to a wide audience, including cell biologists, hematologists, cancer researchers, and HIV/AIDS researchers.

Author : Alice Longobardi Givan
Publisher : John Wiley & Sons
Page : 309 pages
File Size : 48,8 Mb
Release : 2013-04-10
Category : Science
ISBN : 9781118688397

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Flow Cytometry by Alice Longobardi Givan Pdf

Flow cytometry continually amazes scientists with its ever-expanding utility. Advances in flow cytometry have opened new directions in theoretical science, clinical diagnosis, and medical practice. The new edition of Flow Cytometry: First Principles provides a thorough update of this now classic text, reflecting innovations in the field while outlining the fundamental elements of instrumentation, sample preparation, and data analysis. Flow Cytometry: First Principles, Second Edition explains the basic principles of flow cytometry, surveying its primary scientific and clinical applications and highlighting state-of-the-art techniques at the frontiers of research. This edition contains extensive revisions of all chapters, including new discussions on fluorochrome and laser options for multicolor analysis, an additionalsection on apoptosis in the chapter on DNA, and new chapters onintracellular protein staining and cell sorting, including high-speed sorting and alternative sorting methods, as well as traditional technology. This essential resource: Assumes no prior knowledge of flow cytometry Progresses with an informal, engaging lecture style from simpleto more complex concepts Offers a clear introduction to new vocabulary, principles of instrumentation, and strategies for data analysis Emphasizes the theory relevant to all flow cytometry, with examples from a variety of clinical and scientific fields Flow Cytometry: First Principles, Second Edition provides scientists, clinicians, technologists, and students with the knowledge necessary for beginning the practice of flow cytometry and for understanding related literature.

Author : Richard A. McPherson
Publisher : Elsevier India
Page : 1820 pages
File Size : 40,5 Mb
Release : 2016-08-31
Category : Medical
ISBN : 9788131246771

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Henry's Clinical Diagnosis and Management by Laboratory Methods: First South Asia Edition_e-Book by Richard A. McPherson Pdf

To interpret the laboratory results. To distinguish the normal from the abnormal and to understand the merits and demerits of the assays under study. The book attempts to train a laboratory medicine student to achieve sound knowledge of analytical methods and quality control practices, to interpret the laboratory results, to distinguish the normal from the abnormal and to understand the merits and demerits of the assays under study.

Author : Richard A. McPherson,Matthew R. Pincus
Publisher : Elsevier Health Sciences
Page : 1960 pages
File Size : 44,8 Mb
Release : 2021-06-09
Category : Medical
ISBN : 9780323755085

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Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book by Richard A. McPherson,Matthew R. Pincus Pdf

For more than 100 years, Henry's Clinical Diagnosis and Management by Laboratory Methods has been recognized as the premier text in clinical laboratory medicine, widely used by both clinical pathologists and laboratory technicians. Leading experts in each testing discipline clearly explain procedures and how they are used both to formulate clinical diagnoses and to plan patient medical care and long-term management. Employing a multidisciplinary approach, it provides cutting-edge coverage of automation, informatics, molecular diagnostics, proteomics, laboratory management, and quality control, emphasizing new testing methodologies throughout. Remains the most comprehensive and authoritative text on every aspect of the clinical laboratory and the scientific foundation and clinical application of today's complete range of laboratory tests. Updates include current hot topics and advances in clinical laboratory practices, including new and extended applications to diagnosis and management. New content covers next generation mass spectroscopy (MS), coagulation testing, next generation sequencing (NGS), transfusion medicine, genetics and cell-free DNA, therapeutic antibodies targeted to tumors, and new regulations such as ICD-10 coding for billing and reimbursement. Emphasizes the clinical interpretation of laboratory data to assist the clinician in patient management. Organizes chapters by organ system for quick access, and highlights information with full-color illustrations, tables, and diagrams. Provides guidance on error detection, correction, and prevention, as well as cost-effective test selection. Includes a chapter on Toxicology and Therapeutic Drug Monitoring that discusses the necessity of testing for therapeutic drugs that are more frequently being abused by users.

Author : Hillard M. Lazarus,Mary J. Laughlin
Publisher : Springer Science & Business Media
Page : 881 pages
File Size : 43,9 Mb
Release : 2010-03-02
Category : Medical
ISBN : 9781597454780

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Allogeneic Stem Cell Transplantation by Hillard M. Lazarus,Mary J. Laughlin Pdf

Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.

Author : Michael A. Linden,Robert W. McKenna
Publisher : Springer
Page : 152 pages
File Size : 45,8 Mb
Release : 2015-08-05
Category : Medical
ISBN : 9783319109183

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Plasma Cell Neoplasms by Michael A. Linden,Robert W. McKenna Pdf

This textbook will provide a comprehensive, state-of-the art review the field of diagnostic hematopathology as it’s applied to patients with plasma cell neoplasms. Particular emphasis will be placed on immunophenotypic data – immunohistochemistry and flow cytometry – as well as cytogenetics. We will also discuss how these ancillary data can predict prognosis and chemotherapeutic response. Plasma Cell Neoplasms will serve as a very useful resource for physicians and researchers interested in the plasma cell myeloma diagnosis, therapy, and research. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters will be written by experts in their fields and will include the most up to date scientific and clinical information.

Author : World Health Organization
Publisher : IARC
Page : 360 pages
File Size : 54,8 Mb
Release : 2001
Category : Digestive organs
ISBN : 9283224116

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Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues by World Health Organization Pdf

This is the third volume in the new World Health Organization series on histological and genetic typing of tumours. Tumours of the haematopoietic and lymphoid tissues are covered. This was a collaborative project of the European Association for Haematolpathology and the Society for Haematopathology and others. The WHO classification is based on the principles defined in the Revised European-American Classification of Lymphoid Neoplasms (REAL) classification. Over 50 pathologists from around the world were involved in the project and proponents of all major lymphoma and leukaemia classifications have agreed to accept the WHO as the standard classification of haematological malignancies. So this classification represents the first true world wide concensus of haematologic malignancies. Colour photographs, magnetic resonance and ultrasound images and CT scans are included.