Fundamentals Of Advanced Omics Technologies From Genes To Metabolites

Author : Anonim
Publisher : Newnes
Page : 488 pages
File Size : 53,8 Mb
Release : 2014-02-14
Category : Science
ISBN : 9780444626707

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Fundamentals of Advanced Omics Technologies: From Genes to Metabolites by Anonim Pdf

Fundamentals of Advanced Omics Technologies: From Genes to Metabolites covers the fundamental aspects of the new instrumental and methodological developments in omics technologies, including those related to genomics, transcriptomics, epigenetics, proteomics and metabolomics, as well as other omics approaches such as glycomics, peptidomics and foodomics. The principal applications are presented in the following complementary volume. The chapters discuss in detail omics technologies, DNA microarray analysis, next-generation sequencing technologies, genome-wide analysis of methylation and histone modifications, emerging nanotechniques in proteomics, imaging mass spectrometry in proteomics, recent quantitative proteomics approaches, and advances in high-resolution NMR-based metabolomics, as well as MS-based non-targeted metabolomics and metabolome analysis by CE-MS, global glycomics analyses, foodomics, and high resolution analytical tools for quantitative peptidomics. Key aspects related to chemometrics, bioinformatics, data treatment, data integration and systems biology, deep-sequencing data analysis, statistical approaches for the analysis of microarray data, the integration of transcriptome and metabolome data and computational approaches for visualization and integration of omics data are also covered. Covers the latest advances in instrumentation, experimental design, sample preparation, and data analysis Provides thorough explanations and descriptions of specific omics technologies Describes advanced tools and methodologies for data pretreatment, storage, curation and analysis, as well as data integration

Author : Anonim
Publisher : Elsevier
Page : 497 pages
File Size : 50,9 Mb
Release : 2014-05-08
Category : Science
ISBN : 9780444626691

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Applications of Advanced Omics Technologies: From Genes to Metabolites by Anonim Pdf

The book contains contributions concerning the application of the new instrumental and methodological developments in omics technologies, including those related to Genomics, Transcriptomics, Proteomics, Peptidomics and Metabolomics, Lipidomics and Foodomics. The16 chapters discuss in detail: innovative applications of functional gene microarrays for profiling microbial communities, microRNA profiling, novel genotyping applications using microarray technology in cancer research, next-generation sequencing applied to the study of human microbiome, emerging RNA-SEQ applications in food science, recent progress in plant proteomics, applications of gel-free proteomic approaches, the challenges and applications of proteomics tools for food authenticity, the role of salivary peptidomics in clinical applications, metabolomic approaches to the study of degenerative, cardiovascular and renal diseases, and neonatal medicine. Also covered are other omics applications such as profiling of genetically modified organisms, the fundamentals, applications and challenges of foodomics, and MS-based lipidomics. Moreover, this volume includes relevant and updated aspects on bioinformatics, data treatment, data integration and systems biology. This book complements the previous volume "Fundamentals of Advanced Omics Technologies: New Advances from Genes to Metabolites" that covered the fundamental aspects of these new omics technologies. Describes the latest applications of omics technologies Provides an excellent reference for applications of advanced omics techniques Includes advanced tools and methodologies for dealing with the data generated

Author : Silvio Vaz Jr.
Publisher : Elsevier
Page : 238 pages
File Size : 46,9 Mb
Release : 2022-07-01
Category : Science
ISBN : 9780323997362

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Renewable Carbon by Silvio Vaz Jr. Pdf

Renewable Carbon: Science, Technology and Sustainability identifies production pathways and technologies for the production of chemicals and presents relevant information to bridge the gap between reaction engineering and process design. The book uses a multidisciplinary approach, focusing on important aspects of basic science, technological advantages (and hurdles), and key sustainability aspects. It incorporates organic, inorganic and biochemical synthesis and analyzes the myriad of technologies available, including nanotechnology, biotechnology and thermochemistry. Sections cover the synthesis of carbon derivatives through multiple pathways (Science), technologies available for its generation (Technology), and assess sustainability and new supply chains (Sustainability). This book will serve as a valuable reference for academics, research scientists and industry practitioners in green chemistry, chemical engineering, materials science and environmental engineering. Includes a review of sustainable feedstocks containing renewable carbon such as biomass, CO2 and recycling materials Provides a compendium of technologies to explore renewable carbon sources Compiles the most up-to-date information on renewable products and materials utilized in industry

Author : Fatemeh Maghuly,Gorji Marzban,Joanna Jankowicz-Cieslak
Publisher : Frontiers Media SA
Page : 218 pages
File Size : 42,9 Mb
Release : 2022-01-24
Category : Science
ISBN : 9782889715688

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Omics Technologies Toward Systems Biology by Fatemeh Maghuly,Gorji Marzban,Joanna Jankowicz-Cieslak Pdf

Author : Veronica Ghini,Kathleen A. Stringer,Claudio Luchinat
Publisher : Springer Nature
Page : 384 pages
File Size : 53,8 Mb
Release : 2023-03-03
Category : Medical
ISBN : 9783031268595

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Metabolomics and Its Impact on Health and Diseases by Veronica Ghini,Kathleen A. Stringer,Claudio Luchinat Pdf

This volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the NMR approaches are described in the chapters By David Wishart, Daniel Raftery and Ryan McKay, while mass spectrometry advances are covered by Charles R. Evans and Stefan Kempa. This book also reflects the state of the art in the application of metabolomics to cell biology (Marta Cascante and Ulrich Guenther) and chapters that share insights into the application of metabolomics in various diseases (Paola Turano and Claudio Luchinat, Rachel S. Kelly and Jessica Lasky-Su, Paige Lacy, and Angela Rogers. Relationships of metabolomics with drugs are highlighted by Robert Verpoorte (natural products drug discovery), by Oscar Millet and by Turano and Luchinat (perspectives in precision medicine) and by Daniel L. Hertz (drug-induced peripheral neuropathy). From the above list of diverse topics, we believe this book has interdisciplinary appeal and scholars with an interest in the role of metabolomics in achieving precision medicine will find it of particular or special interest.

Author : Ann M. Coulston,Carol J. Boushey,Mario Ferruzzi,Linda Delahanty
Publisher : Academic Press
Page : 1072 pages
File Size : 49,7 Mb
Release : 2017-04-28
Category : Technology & Engineering
ISBN : 9780128029473

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Nutrition in the Prevention and Treatment of Disease by Ann M. Coulston,Carol J. Boushey,Mario Ferruzzi,Linda Delahanty Pdf

Nutrition in the Prevention and Treatment of Disease, Fourth Edition, is a compilation of current knowledge in clinical nutrition and an overview of the rationale and science base of its application to practice in the prevention and treatment of disease. In its fourth edition, this text continues the tradition of incorporating new discoveries and methods related to this important area of research Generating and analyzing data that summarize dietary intake and its association with disease are valuable tasks in treating disease and developing disease prevention strategies. Well-founded medical nutrition therapies can minimize disease development and related complications. Providing scientifically sound, creative, and effective nutrition interventions is both challenging and rewarding. Two new chapters on metabolomics and translational research, which have come to be used in nutrition research in recent years. The new areas of study are discussed with the perspective that the application of the scientific method is by definition an evolutionary process. A new chapter on Genetics and Diabetes which reviews the latest research on causal genetic variants and biological mechanisms responsible for the disease, and explores potential interactions with environmental factors such as diet and lifestyle. Includes all major "omics" – the exposome, metabolomics, genomics, and the gut microbiome. Expands the microbiota portions to reflect complexity of diet on gut microbial ecology, metabolism and health

Author : Shen Hu
Publisher : Springer Nature
Page : 317 pages
File Size : 41,9 Mb
Release : 2021-04-01
Category : Medical
ISBN : 9783030516529

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Cancer Metabolomics by Shen Hu Pdf

Cancer metabolomics is a rapidly evolving field that aims for a comprehensive dissection of the metabolic phenotypes and functional network of metabolites in human cancers. State of the art metabolomics tools have been developed and applied to studying cancer metabolism and developing metabolic targets for improved diagnosis, prognosis and therapeutic treatment of human cancers. Chapters are written by subject experts in the field of cancer metabolomics with cross-disciplinary contributions. Coverage includes advanced metabolomics technologies and methodologies, including chemical isotope labelling liquid chromatography - mass spectrometry, capillary ion chromatography - mass spectrometry, 2-D gas chromatography – mass spectrometry, capillary electrophoresis – mass spectrometry, nuclear magnetic resonance spectroscopy, shotgun lipidomics, tracer-based metabolomics, microbial metabolomics, mass spectrometry imaging for single cell metabolomics and functional metabolomics. In addition, the book highlights new discoveries in cancer metabolism such as hypoxia inducible factor pathway, isocitrate dehydrogenase 1 mutation and oncometabolites. Finally, contributors focus on the translational applications of metabolomics in human cancers such as glioma, head and neck cancer, and gastric cancer. This new volume will be a unique reference source for cancer researchers and promote applications of metabolomics in understanding cancer metabolism.

Author : Noureddine Benkeblia
Publisher : CRC Press
Page : 429 pages
File Size : 55,8 Mb
Release : 2012-01-24
Category : Medical
ISBN : 9781439837078

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OMICs Technologies by Noureddine Benkeblia Pdf

Since the completion of the Human Genome Project, food and nutrition sciences have undergone a fundamental molecular transformation. New discoveries in molecular biology, analytical chemistry, and biochemistry have led to the development of new tools that are likely to revolutionize the study of food. OMICS Technologies: Tools for Food Science expl

Author : Raffaele De Caterina,J. Alfredo Martinez,Martin Kohlmeier
Publisher : Academic Press
Page : 586 pages
File Size : 49,5 Mb
Release : 2019-09-22
Category : Medical
ISBN : 9780128045879

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Principles of Nutrigenetics and Nutrigenomics by Raffaele De Caterina,J. Alfredo Martinez,Martin Kohlmeier Pdf

Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from the most well-cited researchers conducting groundbreaking research in the field, the book covers how the genetic makeup influences the response to foods and nutrients and how nutrients affect gene expression. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is broken into four parts providing a valuable overview of genetics, nutrigenetics, and nutrigenomics, and a conclusion that helps to translate research into practice. With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields. Uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomics Includes a valuable guide to ethics for genetic testing for nutritional advice Chapters include definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts Companion website includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book

Author : Philippe Schmitt-Kopplin,Basem Kanawati
Publisher : Elsevier
Page : 778 pages
File Size : 54,6 Mb
Release : 2019-08-11
Category : Science
ISBN : 9780128140147

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Fundamentals and Applications of Fourier Transform Mass Spectrometry by Philippe Schmitt-Kopplin,Basem Kanawati Pdf

Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data. Covers FT-ICR-MS and Orbitrap’s fundamentals, enhancing researcher knowledge Includes details on ion sources, data processing, chemical analysis and imaging Provides examples across the wide spectrum of applications, including omics, environmental, chemical, pharmaceutical and food analysis

Author : Peter Grunwald
Publisher : World Scientific Publishing Company
Page : 1316 pages
File Size : 50,6 Mb
Release : 2017-08-04
Category : Science
ISBN : 9781783269105

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Biocatalysis by Peter Grunwald Pdf

In this Completely Revised and Extended Edition with a significantly enhanced content, all Chapters have been updated considering relevant literature and recent developments until 2016 together with application oriented examples with a focus on Industrial Biocatalysis. Newly treated topics comprise among others systems metabolic engineering approaches, metagenome screening, new tools for pathway engineering, and de-novo computational design as actual research areas in biocatalysis. Information about different aspects of RNA technologies, and completely new Chapters on 'Fluorescent Proteins' and 'Biocatalysis and Nanotechnology' are also included.

Author : Debmalya Barh,Vasco Ariston De Car Azevedo
Publisher : Academic Press
Page : 645 pages
File Size : 55,6 Mb
Release : 2017-12-01
Category : Technology & Engineering
ISBN : 9780128047491

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Omics Technologies and Bio-engineering by Debmalya Barh,Vasco Ariston De Car Azevedo Pdf

Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 1 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care. Covers various aspects of biotechnology and bio-engineering using omics technologies Focuses on the latest developments in the field, including biofuel technologies Provides key insights into omics approaches in personalized and precision medicine Provides a complete picture on how one can utilize omics data in molecular biology, biotechnology and human health care

Author : Kazuki Saito,Richard A. Dixon,Lothar Willmitzer
Publisher : Springer Science & Business Media
Page : 351 pages
File Size : 45,5 Mb
Release : 2006-06-29
Category : Science
ISBN : 9783540297826

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Plant Metabolomics by Kazuki Saito,Richard A. Dixon,Lothar Willmitzer Pdf

Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology. This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.

Author : Anonim
Publisher : Elsevier
Page : 730 pages
File Size : 41,7 Mb
Release : 2018-09-22
Category : Science
ISBN : 9780444640451

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Data Analysis for Omic Sciences: Methods and Applications by Anonim Pdf

Data Analysis for Omic Sciences: Methods and Applications, Volume 82, shows how these types of challenging datasets can be analyzed. Examples of applications in real environmental, clinical and food analysis cases help readers disseminate these approaches. Chapters of note include an Introduction to Data Analysis Relevance in the Omics Era, Omics Experimental Design and Data Acquisition, Microarrays Data, Analysis of High-Throughput RNA Sequencing Data, Analysis of High-Throughput DNA Bisulfite Sequencing Data, Data Quality Assessment in Untargeted LC-MS Metabolomic, Data Normalization and Scaling, Metabolomics Data Preprocessing, and more. Presents the best reference book for omics data analysis Provides a review of the latest trends in transcriptomics and metabolomics data analysis tools Includes examples of applications in research fields, such as environmental, biomedical and food analysis

Author : Ajit Varki,Maarten J. Chrispeels
Publisher : CSHL Press
Page : 694 pages
File Size : 51,6 Mb
Release : 1999
Category : Medical
ISBN : 0879696818

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Essentials of Glycobiology by Ajit Varki,Maarten J. Chrispeels Pdf

Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.