Gastrointestinal Regulatory Peptides

Author : David R. Brown
Publisher : Springer Science & Business Media
Page : 463 pages
File Size : 41,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642778148

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Gastrointestinal Regulatory Peptides by David R. Brown Pdf

The most comprehensive and conceptual one-volume treatment of this field available and the first to emphasize the cellular and molecular aspects of gut peptide biology. Authored by an array of internationally distinguished scientists, it deals with issues of peptide localization and biosynthesis in gastrointestinal cells, mechanisms of peptide release and inactivation and the nature of peptide receptors. The breadth and readability make it an invaluable reference source for scientists in all disciplines interested in any aspect of brain-gut peptides.

Author : David R Brown,A Alemayehu,B Amiranoff
Publisher : Unknown
Page : 472 pages
File Size : 49,7 Mb
Release : 1993-03-26
Category : Electronic
ISBN : 3642778151

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Gastrointestinal Regulatory Peptides by David R Brown,A Alemayehu,B Amiranoff Pdf

Author : Susanne Holmgren
Publisher : Springer Science & Business Media
Page : 380 pages
File Size : 49,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400908352

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The Comparative Physiology of Regulatory Peptides by Susanne Holmgren Pdf

Strictly speaking, the term regulatory peptides may include any peptide which has a regulatory function in any organism. In recent years, how ever, the term has come to mean those originally classified as brain-gut peptides. The peptides initially defined as those belonging to the brain gut axis had a dual location in neurones of the brain and endocrine cells of the gut. We now include a number of neuropeptides found in the autonomic nervous system of the gut, the cardiovascular system and other systems. To many scientists comparative physiology means comparison of the mechanisms of certain functions in the rat, the guinea-pig, the cat and maybe some other mammal. If the philosophy is that man is the centre of the universe and other mammals can be used as 'models' of man, this may well be the most useful way to study the functions of the human being, without actually chopping somebody up. However, with a some what wider perspective on life, it is easy to see the importance of a full understanding of the function of all living organisms, in its own right as well as a link in the evolution towards individuals able to survive and reproduce in very different environments. The importance of com parative studies in all living organisms cannot be emphasized too much. It has been the ambition with this book to treat all animals as equally important.

Author : Stephen Robert Bloom,Julia M. Polak
Publisher : Unknown
Page : 640 pages
File Size : 47,8 Mb
Release : 1981
Category : Gastrointestinal hormones
ISBN : UOM:39015004413145

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Gut Hormones by Stephen Robert Bloom,Julia M. Polak Pdf

Author : Hubert Vaudry,Marie-Christine Tonon,David Vaudry
Publisher : Frontiers Media SA
Page : 282 pages
File Size : 46,6 Mb
Release : 2018-07-24
Category : Electronic
ISBN : 9782889455379

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Trends in Regulatory Peptides by Hubert Vaudry,Marie-Christine Tonon,David Vaudry Pdf

Regulatory peptides represent the most diverse and versatile family of messenger molecules. They are produced by all living organisms from bacteria to mammals. They are involved in a wide variety of biological functions. Biologically active peptides and their receptors thus constitute an unlimited source of inspiration for the development of innovative drugs and cosmetics. The present eBook is a unique collection of research articles and reviews that provide a representative examplification of the latest progress in regulatory peptide research.

Author : John H. Walsh,G. J. Dockray
Publisher : Raven Press (ID)
Page : 904 pages
File Size : 40,8 Mb
Release : 1994
Category : Medical
ISBN : UOM:39015032878392

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Gut Peptides by John H. Walsh,G. J. Dockray Pdf

Provides a comprehensive approach to gastrointestinal hormones, for clinicians and scientists who are interested in hormonal regulation of the gastrointestinal tract. The first section discusses general issues related to peptides as messengers, including receptors and signal transduction and control of gene expression. The second section presents the biochemical and physiological features of the gastrointestinal hormones and neuropeptides. The third section integrates these peptides into physiological and pathophysiological regulatory pathways of the gut. Annotation copyright by Book News, Inc., Portland, OR

Author : Enrique Blázquez
Publisher : S. Karger AG (Switzerland)
Page : 252 pages
File Size : 48,6 Mb
Release : 1987
Category : Gastrointestinal Hormones
ISBN : UOM:39015012563741

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Gut Regulatory Peptides by Enrique Blázquez Pdf

Author : M. Wabitsch,C. Posovszky
Publisher : Karger Medical and Scientific Publishers
Page : 188 pages
File Size : 42,8 Mb
Release : 2017-08-16
Category : Medical
ISBN : 9783318059748

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Developmental Biology of Gastrointestinal Hormones by M. Wabitsch,C. Posovszky Pdf

The gut not only represents the largest endocrine organ of the human body but is also profoundly involved in the control of metabolism through peptide hormones. Therefore, gastrointestinal hormones are acting via autocrine, paracrine, and classical endocrine pathways and regulate e.g. digestion, hunger, and satiety. Furthermore, they are important regulators of body weight, growth, and glucose metabolism, as well as of mood and behavior. Physicians and scientists in the field of pediatric endocrinology and diabetes, as well as in pediatric gastroenterology, require an extensive understanding of the origin of enteroendocrine cells, factors controlling their differentiation, hormone gene expression, secretion, function and, finally, the complex interaction with other organs, especially the central nervous system. In order to meet these needs, experts in the field have written up-to-date, comprehensive, and illustrated reviews presenting the current knowledge in the field of gastrointestinal endocrinology with a pediatric view. Those reviews comprise this latest volume of Endocrine Development.

Author : Rao N. Jaladanki,Jian-Ying Wang
Publisher : Biota Publishing
Page : 150 pages
File Size : 53,7 Mb
Release : 2016-11-30
Category : Medical
ISBN : 9781615047352

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Regulation of Gastrointestinal Mucosal Growth by Rao N. Jaladanki,Jian-Ying Wang Pdf

The mammalian gastrointestinal mucosa is a rapidly self-renewing tissue in the body, and its homeostasis is preserved through the strict regulation of epithelial cell proliferation, growth arrest, and apoptosis. The control of the growth of gastrointestinal mucosa is unique and, compared with most other tissue in the body, complex. Mucosal growth is regulated by the same hormones that alter metabolism in other tissues, but the gastrointestinal mucosa also responds to host events triggered by the ingestion and presence of food within the digestive tract. These gut hormones and peptides regulate the growth of the exocrine pancreas, gallbladder epithelium, and the mucosa of the oxyntic gland region of the stomach and the small and large intestines. Luminal factors, including nutrients or other dietary factors, secretions, and microbes that occur within the lumen and distribute over a proximal-to-distal gradient, are also crucial for maintenance of normal gut mucosal regeneration and could explain the villous-height-crypt-depth gradient and variety of adaptation, since these factors are diluted, absorbed, and destroyed as they pass down the digestive tract. Recently, intestinal stem cells, cellular polyamines, and noncoding RNAs are shown to play an important role in the regulation of gastrointestinal mucosal growth under physiological and various pathological conditions. In this book, we highlight key issues and factors that control gastrointestinal mucosal growth and homeostasis, with special emphasis on the mechanisms through which epithelial renewal and apoptosis are regulated at the cellular and molecular levels.

Author : Stephen Pandol
Publisher : Morgan & Claypool Publishers
Page : 66 pages
File Size : 45,5 Mb
Release : 2011
Category : Medical
ISBN : 9781615041381

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The Exocrine Pancreas by Stephen Pandol Pdf

The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms.

Author : Jr. Greeley
Publisher : Springer Science & Business Media
Page : 580 pages
File Size : 54,6 Mb
Release : 1998-12-31
Category : Medical
ISBN : 9781592596959

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Gastrointestinal Endocrinology by Jr. Greeley Pdf

Leading clinical and basic science researchers present the latest molecular and cellular findings on key gut peptides, illuminating their physiology and pathophysiology, as well as highlighting the regulatory mechanisms underlying their action in the intestinal tract. The book focuses on gut peptide physiology and receptor pharmacology, gut processing and receptor biology, and on regulatory mechanisms in the gut, including pancreatic feedback mechanisms. Also included are chapters on the trophic effects of gut peptides on GI and pancreatic cancer; the regulation of gut peptide gene expression; and gastric secretion, especially in diseased states.

Author : Edwin E. Daniel
Publisher : CRC Press
Page : 524 pages
File Size : 43,6 Mb
Release : 1990-12-11
Category : Science
ISBN : 0849361583

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Neuropeptide Function in the Gastrointestinal Tract by Edwin E. Daniel Pdf

This book assimilates and evaluates the rapidly accumulating information regarding neuropeptides in the gut, their chemistry; genetic control; processing in enteric nerves; the projections of their nerves; their actions at the tissue, cell, and molecular levels; and their roles in controlling gut motility in health and disease. Neuropeptide Function in the Gastrointestinal Tract is directed to scientists in all disciplines who work with neuropeptides, as well as physiologists interested in the neural and smooth muscle actions of neuropeptides. Gastroenterologists concerned with the control of gastrointestinal motility and the roles of neuroendocrine peptides in regulating motility in health and disease will also find this book to be an indispensable reference resource.This book contains more than 10,000 references and features new areas, including the chemistry of peptides, genetic control of peptides, syntheses, sites and mechanisms of peptide actions, and neuropeptide receptors

Author : John Barton Furness,Marcello Costa
Publisher : Unknown
Page : 312 pages
File Size : 47,5 Mb
Release : 1987
Category : Medical
ISBN : UOM:39015012463215

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The Enteric Nervous System by John Barton Furness,Marcello Costa Pdf

Author : J.M. Polak
Publisher : Birkhäuser
Page : 419 pages
File Size : 53,8 Mb
Release : 2013-03-07
Category : Science
ISBN : 9783034891363

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Regulatory Peptides by J.M. Polak Pdf

J. M. Polak and S. R. Bloom For some time Experientia has published, as a unique feature, interdis ciplinary multi-author reviews, giving a comprehensive overview of sub jects regarded as 'growing edges' of science. The enthusiasm shown by the readers was contagious and thus it was felt necessary to compile a special volume dealing with the novel aspects of regulatory peptides. This book covers some of the growing areas in regulatory peptide research and, although it is based on the original volume of Experientia, it is expanded and updated. The topic of 'regulatory peptides' is relatively young and has grown at an unprecedented pace, from the embryonic conception of 'gut hor mones' or 'brain neuropeptides' some 15 years ago to the realisation that these active pep tides are found, almost without exception, in every part of l8 23 the body in all vertebrate and many invertebrate species • Why the term 'regulatory peptides'? It represents a convenient label encompassing both the active peptides present in nerves, which are re leased as (putative) neurotransmitters, and those in endocrine cells, which act locally or at a distance as circulating hormones, these being the l8 main components of the so-called diffuse neuroendocrine or APUD 17 system • Morphological studies support this physiological viewpoint.

Author : Tibor Gáti,Lajos G. Szollár,György Ungváry
Publisher : Unknown
Page : 0 pages
File Size : 54,5 Mb
Release : 1981
Category : Electronic
ISBN : 9630526913

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Nutrition, Digestion, Metabolism by Tibor Gáti,Lajos G. Szollár,György Ungváry Pdf