Gene Mapping Techniques And Applications

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Gene-Mapping Techniques and Applications

Author : Lawrence B. Schook
Publisher : CRC Press
Page : 353 pages
File Size : 55,5 Mb
Release : 2020-07-24
Category : Science
ISBN : 9781000104639

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Gene-Mapping Techniques and Applications by Lawrence B. Schook Pdf

This book explains current strategies for mapping genomes of higher organisms and explores applications of gene mapping to agriculturally important species of plants and animals. It also explores the experimental techniques used for genetic and physical mapping of genes.

Gene-Mapping Techniques and Applications

Author : Lawrence B. Schook
Publisher : CRC Press
Page : 360 pages
File Size : 44,9 Mb
Release : 2020-07-24
Category : Science
ISBN : 9781000147841

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Gene-Mapping Techniques and Applications by Lawrence B. Schook Pdf

This book explains current strategies for mapping genomes of higher organisms and explores applications of gene mapping to agriculturally important species of plants and animals. It also explores the experimental techniques used for genetic and physical mapping of genes.

Mapping and Sequencing the Human Genome

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Mapping and Sequencing the Human Genome
Publisher : National Academies Press
Page : 128 pages
File Size : 47,9 Mb
Release : 1988-01-01
Category : Science
ISBN : 9780309038409

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Mapping and Sequencing the Human Genome by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Mapping and Sequencing the Human Genome Pdf

There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Genome Mapping and Genomics in Human and Non-Human Primates

Author : Ravindranath Duggirala,Laura Almasy,Sarah Williams-Blangero,Solomon F.D. Paul,Chittaranjan Kole
Publisher : Springer
Page : 305 pages
File Size : 55,8 Mb
Release : 2015-03-25
Category : Science
ISBN : 9783662463062

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Genome Mapping and Genomics in Human and Non-Human Primates by Ravindranath Duggirala,Laura Almasy,Sarah Williams-Blangero,Solomon F.D. Paul,Chittaranjan Kole Pdf

This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., cardiovascular disease, type 2 diabetes, and obesity), anatomic characteristics (e.g., the craniofacial complex), and neurological and behavioral phenotypes (e.g., human brain structure and nonhuman primate behavior) are presented. Topics covered include linkage and association methods, gene expression, copy number variation, next-generation sequencing, comparative genomics, population structure, and a discussion of the Human Genome Project. Further included are discussions of the use of statistical genetic and genetic epidemiologic techniques to decipher the genetic architecture of normal and disease-related complex phenotypes using data from both humans and non-human primates.

Genetic Mapping and DNA Sequencing: Principles, Analysis and Applications

Author : Ashton Ward
Publisher : Callisto Reference
Page : 215 pages
File Size : 55,5 Mb
Release : 2021-11-16
Category : Science
ISBN : 1641165464

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Genetic Mapping and DNA Sequencing: Principles, Analysis and Applications by Ashton Ward Pdf

Proximate DNA sequences on a chromosome are inherited together during sexual reproduction. This tendency of DNA sequences is called genetic linkage. On a chromosome, the closer two genes are, the higher are their chances of being inherited together and lower are the chances of recombination between them. Gene mapping refers to the set of methods that allow the identification of the locus of a gene as well as the distances between genes. It offers evidences regarding the genes that are responsible for the inheritance of disease from parent to child, and also provides clues regarding the location of the genes and the chromosome where they are located. DNA sequencing is the process that determines the nucleic acid sequence or the order of nucleotides in the DNA. It encompasses all methods that can determine the order of the four bases- thymine, guanine, adenine and cytosine. The development of genetic maps and the successful sequencing of the human genome have advanced the frontiers of genetics and medical science. This book aims to shed light on some of the unexplored aspects of genetic mapping and DNA sequencing and the recent researches in these domains. It includes some of the vital pieces of work being conducted across the world, on various topics related to these fields. This book will prove immensely beneficial to geneticists, genetic engineers, students and researchers associated with these areas of study.

Calculating the Secrets of Life

Author : National Research Council,Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on the Mathematical Sciences in Genome and Protein Structure Research
Publisher : National Academies Press
Page : 300 pages
File Size : 47,9 Mb
Release : 1995-04-06
Category : Science
ISBN : 9780309048866

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Calculating the Secrets of Life by National Research Council,Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on the Mathematical Sciences in Genome and Protein Structure Research Pdf

As researchers have pursued biology's secrets to the molecular level, mathematical and computer sciences have played an increasingly important roleâ€"in genome mapping, population genetics, and even the controversial search for "Eve," hypothetical mother of the human race. In this first-ever survey of the partnership between the two fields, leading experts look at how mathematical research and methods have made possible important discoveries in biology. The volume explores how differential geometry, topology, and differential mechanics have allowed researchers to "wind" and "unwind" DNA's double helix to understand the phenomenon of supercoiling. It explains how mathematical tools are revealing the workings of enzymes and proteins. And it describes how mathematicians are detecting echoes from the origin of life by applying stochastic and statistical theory to the study of DNA sequences. This informative and motivational book will be of interest to researchers, research administrators, and educators and students in mathematics, computer sciences, and biology.

Human Gene Mapping Techniques

Author : Helen Donis-Keller
Publisher : Unknown
Page : 250 pages
File Size : 48,6 Mb
Release : 1990-07-01
Category : Human gene mapping
ISBN : 093585987X

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Human Gene Mapping Techniques by Helen Donis-Keller Pdf

Genetic Mapping and Marker Assisted Selection

Author : N. Manikanda Boopathi
Publisher : Springer Nature
Page : 504 pages
File Size : 49,7 Mb
Release : 2020-04-07
Category : Medical
ISBN : 9789811529498

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Genetic Mapping and Marker Assisted Selection by N. Manikanda Boopathi Pdf

The first edition of this book, Genetic Mapping and Marker Assisted Selection: Basics, Practice and Benefits, was widely appreciated as the first of its kind on this topic and has been listed as a reference work in several agricultural universities’ curricula. A great deal has happened over the last five years, making it high time to incorporate recent developments in genetic mapping and report on novel strategies in marker assisted selection in crop plants as a second edition. This book addresses a range of topics, including: new marker types and their genotyping methods based on high-throughput technologies, advances in genomics and their role in new marker development, improvements in genetic mapping strategies and software updates, developments in phenomics and their applications in QTL mapping, and how to incorporate these developments and advances in marker assisted selection in crop plants. Similar to the first edition, each technique and method is explained using a step-by-step method, allowing the book to serve as a self-study guide for scholars whose work involves the genetic improvement of crop plants for any trait of interest, particularly for biotic and abiotic stress resistance. In addition, the book offers a valuable guide for undergraduate and graduate students at agricultural universities and institutes that are interested and/or involved in the genetic improvement of crop plants using modern tools. In addition, the bibliography includes a list of suggested works for pursuing further research on the topics covered.

Plant Genomes: Methods for Genetic and Physical Mapping

Author : J.S. Beckmann,T.C. Osborn
Publisher : Springer Science & Business Media
Page : 233 pages
File Size : 51,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401124423

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Plant Genomes: Methods for Genetic and Physical Mapping by J.S. Beckmann,T.C. Osborn Pdf

JACQUES S. BECKMANN & THOMAS C. OSBORN Extraordinary progress has been made in the analyses of the genetic structures of higher eukaryotic genomes. Only ten years elapsed between the initial proposals to use molecular DNA markers for the generation of a complete linkage map of the human genome [5, 17] and the first description of a 10 centimorgan map of one of its chromosomes [22], soon to be followed by others. The availability of molecular DNA markers, henceforth called genomic markers [for a review of their properties see 1, 2, 20], represents a milestone in genetics by providing the capacity for complete genetic coverage of all genomes. It is important to remember that the nature of the DNA polymorphism or of the specific method used to uncover it can be quite different for different marker loci. The genetic variation detected can be a result of a simple point mutation, a DNA insertion/deletion event, or a change in repeat copy number at some hypervariable DNA [11] or micro satellite [21] motif. Currently, the methods of detection can involve use of restriction endonucleases, nucleic acid hybridization, or DNA sequence amplification. Each of these sources of var iation and methods of detection can have utility for different applications. Furthermore, new approaches for the detection of DNA polymorphism are constantly emerging. The primary concern here is that the monitored poly morphism defines a genetic marker 'useful' for the desired application.

Principles of Biology

Author : Lisa Bartee,Walter Shiner,Catherine Creech
Publisher : Unknown
Page : 128 pages
File Size : 41,5 Mb
Release : 2017
Category : Electronic
ISBN : 1636350410

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Principles of Biology by Lisa Bartee,Walter Shiner,Catherine Creech Pdf

The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.

Human Gene Mapping Techniques

Author : Donis,Helen Donis-Keller
Publisher : C A B International
Page : 128 pages
File Size : 44,5 Mb
Release : 2010-02-28
Category : Science
ISBN : 0195093399

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Human Gene Mapping Techniques by Donis,Helen Donis-Keller Pdf

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Linkage Disequilibrium and Association Mapping

Author : Andrew R. Collins
Publisher : Springer Science & Business Media
Page : 529 pages
File Size : 41,6 Mb
Release : 2008-02-05
Category : Medical
ISBN : 9781597453899

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Linkage Disequilibrium and Association Mapping by Andrew R. Collins Pdf

As researchers continue to make enormous progress in mapping disease genes, exciting, novel, and complex analyses have emerged. In this book, scientists from around the world, who are leaders in this field, contribute their vast experience and expertise to produce a comprehensive and fascinating text for researchers and clinicians alike. They provide cutting-edge analysis of the most up-to-date and preeminent information available.

Genetic Mapping in Experimental Populations

Author : J. W. Van Ooijen,J. Jansen
Publisher : Cambridge University Press
Page : 171 pages
File Size : 53,6 Mb
Release : 2013-08-08
Category : Mathematics
ISBN : 9781107013216

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Genetic Mapping in Experimental Populations by J. W. Van Ooijen,J. Jansen Pdf

A concise introduction to genetic linkage map construction for biological researchers, combining theory with practical exercises and problem-solving tips.

Statistical Genetics

Author : Benjamin Neale,Manuel Ferreira,Sarah Medland,Danielle Posthuma
Publisher : Garland Science
Page : 608 pages
File Size : 47,6 Mb
Release : 2007-11-30
Category : Science
ISBN : 9781134129331

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Statistical Genetics by Benjamin Neale,Manuel Ferreira,Sarah Medland,Danielle Posthuma Pdf

Statistical Genetics is an advanced textbook focusing on conducting genome-wide linkage and association analysis in order to identify the genes responsible for complex behaviors and diseases. Starting with an introductory section on statistics and quantitative genetics, it covers both established and new methodologies, providing the genetic and statistical theory on which they are based. Each chapter is written by leading researchers, who give the reader the benefit of their experience with worked examples, study design, and sources of error. The text can be used in conjunction with an associated website (www.genemapping.org) that provides supplementary material and links to downloadable software.

Advanced Techniques in Chromosome Research

Author : Kenneth W. Adolph
Publisher : CRC Press
Page : 488 pages
File Size : 51,9 Mb
Release : 1991-03-28
Category : Science
ISBN : 0824784308

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Advanced Techniques in Chromosome Research by Kenneth W. Adolph Pdf

Contributors detail up-to-date guidelines for using molecular techniques, cytogenetic and linkage analysis, and cellular methods, emphasizing human cells and medically relevant research. They present results of recent applications of techniques and step-by-step protocols for cloning large DNA molecu