Glial Cell Function

Author : Alexei Verkhratsky,Arthur Butt
Publisher : John Wiley & Sons
Page : 230 pages
File Size : 49,7 Mb
Release : 2007-08-20
Category : Medical
ISBN : 0470513071

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Glial Neurobiology by Alexei Verkhratsky,Arthur Butt Pdf

"This volume is a very valuable and much needed contribution." –Quarterly Review of Biology AT LAST - A comprehensive, accessible textbook on glial neurobiology! Glial cells are the most numerous cells in the human brain but for many years have attracted little scientific attention. Neurophysiologists concentrated their research efforts instead, on neurones and neuronal networks because it was thought that they were the key elements responsible for higher brain function. Recent advances, however, indicate this isn’t exactly the case. Not only are astroglial cells the stem elements from which neurones are born, but they also control the development, functional activity and death of neuronal circuits. These ground-breaking developments have revolutionized our understanding of the human brain and the complex interrelationship of glial and neuronal networks in health and disease. Features of this book: an accessible introduction to glial neurobiology including an overview of glial cell function and its active role in neural processes, brain function and nervous system pathology an exploration of all the major types of glial cells including: the astrocytes, oligodendrocytes and microglia of the ACNS and Schwann cells of the peripheral nervous system; the book also presents a broad overview of glial receptors and ion channels an investigation into the role of glial cells in various types of brain diseases including stroke, neurodegenerative diseases such as Alzheimer's, Parkinson's and Alexander's disease, brain oedema, multiple sclerosis and many more a wealth of illustrations, including unique images from the authors' own libraries of images, describing the main features of glial cells Written by two leading experts in the field, Glial Neurobiology provides a concise, authoritative introduction to glial physiology and pathology for undergraduate/postgraduate neuroscience, biomedical, medical, pharmacy, pharmacology, and neurology, neurosurgery and physiology students. It is also an invaluable resource for researchers in neuroscience, physiology, pharmacology and pharmaceutics.

Author : Rommy von Bernhardi
Publisher : Springer
Page : 348 pages
File Size : 45,5 Mb
Release : 2016-10-06
Category : Medical
ISBN : 9783319407647

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Glial Cells in Health and Disease of the CNS by Rommy von Bernhardi Pdf

A timely overview covering the three major types of glial cells in the central nervous system - astrocytes, microglia, and oligodendrocytes. New findings on glia biology are overturning a century of conventional thinking about how the brain operates and are expanding our knowledge about information processing in the brain. The book will present recent research findings on the role of glial cells in both healthy function and disease. It will comprehensively cover a broad spectrum of topics while remaining compact in size.

Author : Bernardo Castellano,B. Castellano Lopez,M. Nieto-Sampedro
Publisher : Gulf Professional Publishing
Page : 790 pages
File Size : 42,8 Mb
Release : 2003-09-15
Category : Medical
ISBN : 0444514864

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Glial Cell Function (Paperback) by Bernardo Castellano,B. Castellano Lopez,M. Nieto-Sampedro Pdf

Although knowledge of the development and differentiation of glial cells has significantly increased in recent years, there are still many questions unanswered. The first section of the book is devoted to this very active topic and includes contributions on Schwann cells, oligodendrocytes, astroglia and microglia. The second section of the book covers cellular interactions, the role they play on myelination and remyelination, how these interactions take place and the molecules involved. The third section of this volume focuses on the interactions of neurons with glial cells and their role in brain function. Neuron-glia cross talk appears to be fundamental for synaptic transmission and several chapters in this section address this topic. The topic of how glial cells react to brain injury and how they participate in neuroprotection and brain repair is covered in section four of this book. As our knowledge about the molecules involved in the regenerative properties of glia increases, new avenues are open for the use of genetically modified glia with therapeutic purposes. The final section of the book is devoted to therapeutic approaches to tumours, viral and prion infections. Gene therapy is a promising approach for the treatment of gliomas, one of the most devastating forms of cancer. A chapter on prion diseases and microglia addresses a question of tremendous actuality, since prion diseases in cows is at this moment the major veterinary problem in Europe and has created a considerable social alarm.

Author : Firas H. Kobeissy
Publisher : CRC Press
Page : 718 pages
File Size : 42,5 Mb
Release : 2015-02-25
Category : Medical
ISBN : 9781466565999

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Brain Neurotrauma by Firas H. Kobeissy Pdf

With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Author : B. Castellano López,Manuel Nieto-Sampedro
Publisher : Unknown
Page : 757 pages
File Size : 44,9 Mb
Release : 2001
Category : Electronic
ISBN : 0444801049

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Glial Cell Function by B. Castellano López,Manuel Nieto-Sampedro Pdf

Author : Kristjan R. Jessen,William David Richardson
Publisher : Unknown
Page : 504 pages
File Size : 40,5 Mb
Release : 2001
Category : Medical
ISBN : UOM:39015054436038

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Glial Cell Development by Kristjan R. Jessen,William David Richardson Pdf

The majority of cells in the nervous system are glial cells. During de velopment, these cells provide growth factors that stimulate the proli feration, migration and survival of neurones and their precursors, and promote and guide axonal growth. In the mature nervous system, glial cells provide insulating myelin sheath around axons and provide metabo lic and structural support for neurones. Glial cells also have a major influence on the local response to injury of central nerve tracts and the peripheral nervous system, either promoting, or inhibiting, axona l regrowth and recovery of lost function. This book provides a compreh ensive, state-of-the-art overview of research into the development, fu nction and malfunction of glial cells. It offers a compelling insight into how basic research throws light onto diseases and disorders and p oints the way towards treatments. Teams of internationally renowned ex perts, all active in research, have contributed chapters.

Author : Andrew Koob
Publisher : FT Press
Page : 194 pages
File Size : 52,8 Mb
Release : 2009-06-03
Category : Medical
ISBN : 9780138006273

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The Root of Thought by Andrew Koob Pdf

Until recently, neuroscientists thought glial cells did little more than hold your brain together. But in the past few years, they've discovered that glial cells are extraordinarily important. In fact, they may hold the key to understanding intelligence, treating psychiatric disorders and brain injuries and perhaps even curing fatal conditions like Alzheimer's, Parkinson's, and Lou Gehrig's Disease. In The Root of Thought, leading neuroscientist Dr. Andrew Koob reveals what we've learned about these remarkable cells, from their unexpected role in information storage to their function as adult stem cells that can keep your brain growing and adapting longer than scientists ever imagined possible. Ranging from fruit flies to Einstein, Koob reveals the surprising correlation between intelligence and the brain's percentage of glial cells - and why these cells' unique wavelike communications may be especially conducive to the fluid information processing human beings depend upon. You'll learn how crucial glial cells grow and develop... why almost all brain tumors are comprised of glial cells and the potential implications for treatment... even the apparent role of glial cells in your every thought and dream!

Author : Rebecca Matsas,Marco Tsacopoulos
Publisher : Springer Science & Business Media
Page : 376 pages
File Size : 42,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461546856

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The Functional Roles of Glial Cells in Health and Disease by Rebecca Matsas,Marco Tsacopoulos Pdf

Thirty-five years ago, when Stephen Kuffler and his colleagues at Harvard initiated a new era of research on the properties and functions of neuroglial cells, very few neuro scientists were impressed at the time with the hypothesis that neuroglial cells could have another, though more subtle, role to play in the nervous system than to provide static support to neurons. Today, very few neuroscientists are unaware of the fact that multiple interactions between neurons and glial cells have been described, and that they consti tute the basis for understanding the function and the pathology of the nervous system. Glial cells outnumber neurons and make up about one-half of the bulk of the nervous system. They are divided into two major classes: first, the macroglia, which include astrocytes and oligodendrocytes in the central nervous system, and the Schwann cells in the peripheral nervous system; and second, the microglial cells. These different classes of glial cells have different functions and contribute in different ways in the devel opment, function, and the pathology of the nervous system.

Author : Ishan Patro,Pankaj Seth,Nisha Patro,Prakash Narain Tandon
Publisher : Springer Nature
Page : 763 pages
File Size : 48,6 Mb
Release : 2022-04-09
Category : Medical
ISBN : 9789811683138

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The Biology of Glial Cells: Recent Advances by Ishan Patro,Pankaj Seth,Nisha Patro,Prakash Narain Tandon Pdf

This book reviews the role of glial cells (astrocytes, microglia, oligodendroglia, satellite cells, and Schwann cells) in neuronal health and diseases. It discusses the latest advances in understanding their origin, differentiation, and hemostasis. The book also examines the role of microglial cells in central nervous system (CNS) development, maintenance, and synaptic plasticity. Further, the book presents the functions of astrocytes in healthy CNS and their critical role in CNS disorders, including Parkinson's and Alzheimer's diseases. Notably, the book describes the pathobiology, molecular pathogenesis, stem cells, and imaging characteristics of gliomas. It defines the role of glial cells in regulating iron homeostasis and their effect on the neurodegeneration of neurons. Lastly, it covers the structure, function, and pathology of oligodendrocytes and their role in neuronal health and disease. ​

Author : Samantha Fowler,Rebecca Roush,James Wise
Publisher : Unknown
Page : 618 pages
File Size : 51,6 Mb
Release : 2018-01-07
Category : Science
ISBN : 9888407457

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Concepts of Biology by Samantha Fowler,Rebecca Roush,James Wise Pdf

Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.

Author : Peter R. Laming,Eva Syková
Publisher : Cambridge University Press
Page : 448 pages
File Size : 43,5 Mb
Release : 1998-06-28
Category : Medical
ISBN : 0521573688

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Glial Cells by Peter R. Laming,Eva Syková Pdf

This 1998 book discusses how neurons and glial cells interact with each other to influence behaviour.

Author : Helmut Kettenmann,Bruce R. Ransom
Publisher : Oxford University Press
Page : 628 pages
File Size : 41,5 Mb
Release : 2005
Category : Medical
ISBN : 0195152220

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Neuroglia by Helmut Kettenmann,Bruce R. Ransom Pdf

Graduate students in neuroanatomy, neurochemistry, neurophysiology, and molecular neurobiology will find the book indispensable. It is also a vital companion for researchers in these fields as well as clinicians in neurology, neurosurgery, neuropathology, neuro-oncology, physiatry, and psychiatry."--BOOK JACKET.

Author : Alexei Verkhratsky,Arthur Butt
Publisher : John Wiley & Sons
Page : 473 pages
File Size : 49,5 Mb
Release : 2013-01-31
Category : Medical
ISBN : 9781118402054

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Glial Physiology and Pathophysiology by Alexei Verkhratsky,Arthur Butt Pdf

Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells. Coverae includes: the morphology and interrelationships between glial cells and neurones in different parts of the nervous systems the cellular physiology of the different kinds of glial cells the mechanisms of intra- and inter-cellular signalling in glial networks the mechanisms of glial-neuronal communications the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system the cellular and molecular mechanisms of metabolic neuronal-glial interactions the role of glia in nervous system pathology, including pathology of glial cells and associated diseases - for example, multiple sclerosis, Alzheimer's, Alexander disease and Parkinson's Neuroglia oversee the birth and development of neurones, the establishment of interneuronal connections (the 'connectome'), the maintenance and removal of these inter-neuronal connections, writing of the nervous system components, adult neurogenesis, the energetics of nervous tissue, metabolism of neurotransmitters, regulation of ion composition of the interstitial space and many, many more homeostatic functions. This book primes the reader towards the notion that nervous tissue is not divided into more important and less important cells. The nervous tissue functions because of the coherent and concerted action of many different cell types, each contributing to an ultimate output. This reaches its zenith in humans, with the creation of thoughts, underlying acquisition of knowledge, its analysis and synthesis, and contemplating the Universe and our place in it. An up-to-date and fully referenced text on the most numerous cells in the human brain Detailed coverage of the morphology and interrelationships between glial cells and neurones in different parts of the nervous system Describes the role og glial cells in neuropathology Focus boxes highlight key points and summarise important facts Companion website with downloadable figures and slides

Author : Helga Kolb,Eduardo Fernandez,Ralph Nelson
Publisher : Unknown
Page : 128 pages
File Size : 53,6 Mb
Release : 2007
Category : Electronic
ISBN : OCLC:503519994

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Webvision by Helga Kolb,Eduardo Fernandez,Ralph Nelson Pdf

Author : Michael Aschner,Lucio G. Costa
Publisher : CRC Press
Page : 477 pages
File Size : 51,7 Mb
Release : 2004-12-28
Category : Medical
ISBN : 9781420039740

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The Role of Glia in Neurotoxicity by Michael Aschner,Lucio G. Costa Pdf

Presenting the latest research in glial cell function gleaned from new techniques in imaging and molecular biology, The Role of Glia in Neurotoxicity, Second Edition covers multiple aspects of glial cells, including morphology, physiology, pharmacology, biochemistry, pathology, and their involvement in the pathophysiology of neurological diseases.