Green And Sustainable Medicinal Chemistry

Author : Bimal Krishna Banik
Publisher : Elsevier
Page : 699 pages
File Size : 50,9 Mb
Release : 2024-05-31
Category : Science
ISBN : 9780443161674

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Green Approaches in Medicinal Chemistry for Sustainable Drug Design by Bimal Krishna Banik Pdf

Extensive experimentation and high failure rates are a well-recognized downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry 2e reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context to the growth of green chemistry in relation to drug discovery, the book goes on to identify a broad range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global team of experts, Sustainable and Green Approaches in Medicinal Chemistry, Second Edition encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists and all those in related fields across both academia and industry in integrating these approaches into their own work. This second volume of the second edition includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods. Highlights the need for adoption of sustainable and green chemistry pathways in drug development Reveals risk factors associated with the drug development process and the ways sustainable approaches can help address these Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability

Author : Marianna Torok
Publisher : Elsevier
Page : 568 pages
File Size : 43,8 Mb
Release : 2022-08-26
Category : Medical
ISBN : 9780128232712

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Contemporary Chemical Approaches for Green and Sustainable Drugs by Marianna Torok Pdf

Contemporary Chemical Approaches for Green and Sustainable Drugs provides readers with the knowledge they need to integrate sustainable approaches into their work. Sections cover different aspects of green and sustainable drug development from design to disposal, including computer-aided drug design, green resourcing of drugs and drug candidates, an overview of the health concerns of pharmaceutical pollution, and a survey of potential chemical methods for its reduction. Drawing together the knowledge of a global team of experts, this book provides an inclusive overview of the chemical tools and approaches available for minimizing the negative environmental impact of current and newly developed drugs. This will be a useful guide for all academic and industrial researchers across green and sustainable chemistry, medicinal chemistry, environmental chemistry and pharmaceutical science. Provides an integrative overview of the environmental risks of drugs and drug by products to support chemists in pre-emptively addressing these issues Highlights the advantages of computer-aided drug design, green and sustainable sourcing, and novel methods for the production of safer, more effective drugs Presents individual chapters written by renowned experts with diverse backgrounds Reflects research in practice through selected case studies and extensive state-of-the-art reference sections to serve as a starting point in the design of any specialized environmentally-conscious medicinal chemistry project

Author : Louise Summerton,Helen F. Sneddon,Leonie C. Jones,James H. Clark
Publisher : Royal Society of Chemistry
Page : 272 pages
File Size : 46,7 Mb
Release : 2016
Category : Science
ISBN : 9781782624677

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Green and Sustainable Medicinal Chemistry by Louise Summerton,Helen F. Sneddon,Leonie C. Jones,James H. Clark Pdf

Author : Wei Zhang,Berkeley W. Cue
Publisher : John Wiley & Sons
Page : 726 pages
File Size : 41,9 Mb
Release : 2018-03-19
Category : Science
ISBN : 9781119288169

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Green Techniques for Organic Synthesis and Medicinal Chemistry by Wei Zhang,Berkeley W. Cue Pdf

An updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.

Author : Satish A. Dake,Ravindra S. Shinde,Suresh C. Ameta,A. K. Haghi
Publisher : Apple Academic Press
Page : 318 pages
File Size : 40,6 Mb
Release : 2020-08-24
Category : SCIENCE
ISBN : 1771888628

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Green Chemistry and Sustainable Technology by Satish A. Dake,Ravindra S. Shinde,Suresh C. Ameta,A. K. Haghi Pdf

Taking an interdisciplinary approach, this new volume, Green Chemistry and Sustainable Technology: Biological, Pharmaceutical, and Macromolecular Systems, brings together innovative research, new concepts, and novel developments in the application of new tools in green chemistry and sustainable technology. The diverse coverage includes chapters on ionic liquids as green solvents, an environmentally friendly approach to the synthesis and biological evaluation of α-aminophosphonate derivatives, the application of nanotechnology in biological sciences and green chemistry, ecofriendly polymers, the effect of global warming and greenhouse gases on environmental system, and more. This volume will appeal to chemists and engineers in chemical industry and research who should benefit from the technological, scientific, and economic interrelationships and their potential developments.

Author : Tahmeena Khan,Abdul Rahman Khan,Saman Raza,Iqbal Azad,Alfred J. Lawrence
Publisher : Bentham Science Publishers
Page : 270 pages
File Size : 49,9 Mb
Release : 2021-09-02
Category : Science
ISBN : 9789814998284

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Medicinal and Environmental Chemistry: Experimental Advances and Simulations (Part I) by Tahmeena Khan,Abdul Rahman Khan,Saman Raza,Iqbal Azad,Alfred J. Lawrence Pdf

Medicinal and Environmental Chemistry: Experimental Advances and Simulations is a collection of topics that highlight the use of pharmaceutical chemistry to assess the environment or make drug design and chemical testing more environment friendly. The ten chapters included in the first part of this book set cover diverse topics, blending the fields of environmental chemistry and medicinal chemistry and have been authored by experts, scientists and academicians from renowned institutions. The book introduces the reader to environmental contaminants and techniques for their quantification and removal. A medicinal perspective for effects and remediation of environmental hazards, and therapeutic strategies available to design new and safer drugs, is addressed with a focus on knowledge about experimental and simulation methods. To further elaborate the importance of environmentally safe chemical practice, the concept of green chemistry has also been covered. Specialized chapters have been included in the book about persistent organic pollutants, heavy metal and plastic pollutants, the effect of environmental xenoesterogens on human health and the potential of natural products to combat ecotoxicity. Key Features: 1. 10 topics which blend environmental chemistry and medicinal chemistry 2. Contributions from more than 30 experts 3. Includes introductory topics on environmental pollutants, investigative techniques in drug design and environmental risk assessment and green chemistry 4. Includes specialized topics on persistent pollutants, ecotoxicity remediation and xenoestrogens 5. Bibliographic references This reference is an essential source of information for readers and scholars involved in environmental chemistry, pollution management and pharmaceutical chemistry courses at graduate and undergraduate levels. Professionals and students involved in occupational medicine will also benefit from the wide range of topics covered.

Author : Bimal Krishna Banik
Publisher : Elsevier
Page : 658 pages
File Size : 51,6 Mb
Release : 2024-06-07
Category : Science
ISBN : 9780443161650

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Green Approaches in Medicinal Chemistry for Sustainable Drug Design by Bimal Krishna Banik Pdf

Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry, Second Edition reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context to the growth of green chemistry in relation to drug discovery, the book goes on to identify a broad range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global team of experts, Sustainable and Green Approaches in Medicinal Chemistry 2e encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists and all those in related fields across both academia and industry in integrating these approaches into their own work. This first volume of the second edition covers synthesis methods following green chemistry principles, contributing to sustainability by saving energy, using lesser toxic reagents/solvents/catalysts and environmentally benign sources including plants and agricultural materials. Highlights the need for the adoption of sustainable and green chemistry pathways in drug development Reveals risk factors associated with the drug development process and the ways sustainable approaches can help address these factors Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability

Author : Paul F. Richardson
Publisher : Humana
Page : 595 pages
File Size : 55,5 Mb
Release : 2021-10-26
Category : Medical
ISBN : 1071615777

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Green Chemistry in Drug Discovery by Paul F. Richardson Pdf

This detailed book highlights several emerging areas in the implementation of green chemistry in medicinal chemistry drug discovery with a specific focus on their application to the expeditious discovery of new biologically active entities. Divided into three sections, the collection explores greener approaches to chemical transformations that are both prevalent and have been highlighted as challenging within the pharmaceutical industry, overall synthetic strategy, as well as the implementation and impact of a range of enabling technologies within medicinal chemistry. As a volume of the Methods in Pharmacology and Toxicology series, chapters provide the kind of key insight that can guide researchers toward greater success in the lab. Authoritative and practical, Green Chemistry in Drug Discovery: From Academia to Industry provides both a fundamental insight into the progress that has been made as well as some of the challenges that still exist for these techniques to be effectively implemented in the drug discovery process in a routine manner.

Author : Emily A. Peterson,Julie B. Manley
Publisher : Royal Society of Chemistry
Page : 338 pages
File Size : 40,6 Mb
Release : 2015-06-30
Category : Medical
ISBN : 9781849739610

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Green Chemistry Strategies for Drug Discovery by Emily A. Peterson,Julie B. Manley Pdf

The incorporation of Green Chemistry is a relatively new phenomenon in the drug discovery discipline, since the scale that chemists operate on in drug discovery is smaller than those of process and manufacturing chemistry. The necessary metrics are more difficult to obtain in drug discovery due to the diversity of reactions conducted. However, pharmaceutical companies are realizing that incorporation of green chemistry techniques at earlier stages of drug development can speed the development of a drug candidate. Edited by experts who have pioneered green chemistry efforts within their own institutions, this book provides a practical guide for both academic and industrial labs wanting to know where to start with introducing greener approaches for greatest return on investment. The Editors have taken a comprehensive approach to the topic covering the entire drug discovery process from molecule conception, through synthesis, formulation and toxicology with specific examples and case studies where green chemistry strategies have been implemented. Currently employed as well as emerging techniques for performing greener drug discovery chemistry are addressed as well as cutting-edge topics like biologics discovery. Moreover, important surrounding issues such as intellectual property are included. This book will serve as a practical guide for both academic and industrial chemists who work across the breadth of the drug discovery discipline. Ultimately, readers will learn how to incorporate green chemistry strategies into their everyday workflow without slowing down their science.

Author : Stefan Koenig
Publisher : CRC Press
Page : 378 pages
File Size : 55,8 Mb
Release : 2013-09-11
Category : Medical
ISBN : 9789814364812

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Scalable Green Chemistry by Stefan Koenig Pdf

Packed with real-world examples, this book illustrates the 12 principles of green chemistry. These diverse case studies demonstrate to scientists and students that beyond the theory, the challenges of green chemistry in pharmaceutical discovery and development remain an ongoing endeavor. By informing and welcoming additional practitioners to this m

Author : Klaus Kümmerer,Maximilian Hempel
Publisher : Springer Science & Business Media
Page : 312 pages
File Size : 46,8 Mb
Release : 2010-06-16
Category : Technology & Engineering
ISBN : 9783642051999

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Green and Sustainable Pharmacy by Klaus Kümmerer,Maximilian Hempel Pdf

Within recent years pharmaceuticals have come into focus as contaminants of the environment (see for example Kümmerer, K. editor: Pharmaceuticals in the Environment). At the same time the issue of sustainable chemistry gained momentum. Bringing both together would result in sustainable pharmacy. Sustainable pharmacy is a totally new issue and approach. It addresses environmental, economical and social aspects of pharmacy. In the present stage the focus will be on environmental issues along the whole lifecycle of a pharmaceutical entity. That is dealing with resources and energy input but also with waste issues for example during the synthesis and production of an active pharmaceutical ingredient. Furthermore, it would also look on the compounds themselves and will aim to improve the degradability of the compounds after their use in the environment to reduce the environmental risk caused by pharmaceuticals in the environment. Another issue is the people using pharmaceuticals such as pharmacists, medical doctors and patients. How can they contribute to more efficient use of pharmaceuticals with less environmental burden and less risk for drinking water. The book "Sustainable Pharmacy" will address all these issues and will be the first one dealing with this important topic.

Author : Ying Li,Farid Chemat
Publisher : Springer
Page : 375 pages
File Size : 52,6 Mb
Release : 2019-07-08
Category : Science
ISBN : 9789811338106

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Plant Based “Green Chemistry 2.0” by Ying Li,Farid Chemat Pdf

This book provides practical information on obtaining and using a wide variety of plant based reagents for different sectors, addressing the needs and challenges in a single resource. The chapters complement each other seamlessly and present contributions from reputed international researchers and renowned professionals from industry, covering the latest efforts in the field. The book serves as the starting point for future collaborations in the new area “Plant Based Green Chemistry” between research, industry, and education, covering large ecologic and economic applications: perfume, cosmetic, pharmaceutical, food ingredients, nutraceuticals, biofuels, or fine chemicals industries. This book is aimed at professionals from industries, academicians engaged in plant based green chemistry, researchers and graduate level students, but will also be useful to food technologists and students and researchers involved in natural products chemistry.

Author : Inamuddin,Rajender Boddula,Abdullah M. Asiri
Publisher : Elsevier
Page : 242 pages
File Size : 41,8 Mb
Release : 2021-11-17
Category : Technology & Engineering
ISBN : 9780128198513

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Green Sustainable Process for Chemical and Environmental Engineering and Science by Inamuddin,Rajender Boddula,Abdullah M. Asiri Pdf

Green Sustainable Process for Chemical and Environmental Engineering and Science: Switchable Solvents explores the preparation, properties, chemical processes and applications of this class of green solvents. The book provides an in-depth overview on the area of switchable solvents in various industrial applications, focusing on the purification and extraction of chemical compounds utilizing green chemistry protocols that include liquid-liquid, solid-liquid, liquid-gas and lipids separation technologies. In addition, it includes recent advances in greener extraction and separation processes. This book will be an invaluable guide to students, professors, scientists and R&D industrial specialists working in the field of sustainable chemistry, organic, analytical, chemical engineering, environmental and pharmaceutical sciences. Provides a broad overview of switchable solvents in sustainable chemical processes Compares the use of switchable solvents as greener solvents over conventional solvents Outlines eco-friendly organic synthesis and chemical processes using switchable solvents Lists various industrial separations/extraction processes using switchable solvents

Author : Hosam El-Din M. Saleh,Martin Koller
Publisher : BoD – Books on Demand
Page : 191 pages
File Size : 55,8 Mb
Release : 2018-02-28
Category : Science
ISBN : 9789535138471

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Green Chemistry by Hosam El-Din M. Saleh,Martin Koller Pdf

To an increasing extent, "green chemistry" is a new chemical and engineering approach of chemistry and engineering, dedicated to make manufacturing processes and our world as a whole more sustainable world with a growing tendency. "Green chemistry" approaches are based on ecofriendly technologies, aiming to reduce or eliminate the use of solvents, or render them efficient and safer. Moreover, this scientific field is devoted to reduction or elimination of prevailing environmental and health threats, which typically accompany chemical products and traditional processes. The present book "Green Chemistry" contains 9 selected chapters, starting with a general introductory chapter on "green chemistry," and covers many recent applications and developments based on the principles of "green chemistry." This book is considered the appropriate way to communicate the advances in green materials and their applications to the scientific community. Chemists, scientists and researchers from related areas, and undergraduates involved in environmental issues and interested in approaches to improve the quality of life could find an inspiring and effective guide by reading this book.

Author : Mariette M Pereira,Mário J F Calvete
Publisher : Royal Society of Chemistry
Page : 245 pages
File Size : 53,7 Mb
Release : 2018-03-26
Category : Science
ISBN : 9781788014410

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Sustainable Synthesis of Pharmaceuticals by Mariette M Pereira,Mário J F Calvete Pdf

There is a growing interest in the development of sustainable processes for the synthesis of pharmaceuticals and this book bridges the divide between industrial examples and the fundamental chemistry. It explains the basic principles of using transition metal catalysis with several green approaches for the synthesis of pharmaceuticals. The topic is an important one for green chemistry and the chapters in this book on hydroformylation, green oxidation and olefin metathesis will also be of interest to both medicinal and organic chemists. Written by leading experts in the field, it provides a valuable and easy tool for scientists and industrialists who require information regarding this topic.