Guidelines For The Testing Of Chemicals For Carcinogenicity

Author : Great Britain. Committee on Carcinogenicity of Chemicals in Food, Consumer Products, and the Environment,Great Britain. Department of Health and Social Security
Publisher : Unknown
Page : 46 pages
File Size : 49,8 Mb
Release : 1982
Category : Carcinogenicity testing
ISBN : IND:30000138827880

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Guidelines for the Testing of Chemicals for Carcinogenicity by Great Britain. Committee on Carcinogenicity of Chemicals in Food, Consumer Products, and the Environment,Great Britain. Department of Health and Social Security Pdf

Author : OECD
Publisher : OECD Publishing
Page : 20 pages
File Size : 40,9 Mb
Release : 2018-06-27
Category : Electronic
ISBN : 9789264071223

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies by OECD Pdf

The objective of a combined chronic toxicity/carcinogenicity study is to identify carcinogenic and the majority of chronic effects, and to determine dose-response relationships following prolonged and repeated exposure. The rat is typically used for ...

Author : OECD
Publisher : OECD Publishing
Page : 112 pages
File Size : 54,5 Mb
Release : 2002-12-12
Category : Electronic
ISBN : 9789264078499

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OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies by OECD Pdf

These Guidance Notes outline core concepts in order to obviate the need to consult large numbers of text books, while still pointing the reader to sources of more detailed or specific information.

Author : OECD
Publisher : OECD Publishing
Page : 15 pages
File Size : 41,6 Mb
Release : 2018-06-27
Category : Electronic
ISBN : 9789264071186

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 451: Carcinogenicity Studies by OECD Pdf

The objective of a long-term carcinogenicity study is to observe test animals for a major portion of their life span for the development of neoplastic lesions during or after exposure to various doses of a test substance by an appropriate route of ...

Author : OECD
Publisher : OECD Publishing
Page : 156 pages
File Size : 52,6 Mb
Release : 2014-09-03
Category : Electronic
ISBN : 9789264221475

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OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies, Supporting Test Guidelines 451, 452 and 453 Second edition by OECD Pdf

This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453.

Author : Great Britain. Committee on Carcinogenicity of Chemicals in Food, Consumer Products, and the Environment,Great Britain. Department of Health
Publisher : Unknown
Page : 106 pages
File Size : 43,6 Mb
Release : 1991
Category : Medical
ISBN : STANFORD:36105041273579

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Guidelines for the Evaluation of Chemicals for Carcinogenicity by Great Britain. Committee on Carcinogenicity of Chemicals in Food, Consumer Products, and the Environment,Great Britain. Department of Health Pdf

Author : H.C. Grice
Publisher : Springer Science & Business Media
Page : 200 pages
File Size : 52,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642493713

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Interpretation and Extrapolation of Chemical and Biological Carcinogenicity Data to Establish Human Safety Standards by H.C. Grice Pdf

The International Life Sciences Institute (lLSI) is a scientific foundation wh ich addresses critical health and safety issues of national and international concern. ILSI promotes international cooperation by pro viding the mechanism for scientists from government, industry and universities to work together on cooperative programs to generate and disseminate scientific data. The members and trustees of the Institute believe that questions regarding health and safety are best resolved when scientists can ex amine and discuss issues, as an independent body, se~arate from the political pressures of individual countries and the economic concerns of individual companies. Frequently, meaningful assessment of the risk of a test substance is hindered by the inherent inconsistencies in the system. The development and refinement of methods and systems to evaluate the safety of chemicals have evolved in a rapid and largely unplanned fashion. Attempts to improve the system have largely been directed toward broad general concerns, with little attention being given to specific problems or issues. A failure to resolve these problems has frequently resulted in increased testing costs and complications in the assessment and extrapolation of the results. Publicity surrounding toxicologic issues has created chronic public apprehension about the ability of science and government to deal effectively with these problems. In response to these difficulties, ILSI has assembled highly qualified and renowned scientists from research institutes, universities, government and industry, with relevant scientific knowledge and expertise regarding the issues that complicate risk assessment procedures.

Author : National Institutes of Health (U.S.)
Publisher : Unknown
Page : 24 pages
File Size : 44,8 Mb
Release : 1981
Category : Carcinogens
ISBN : MINN:31951003060067L

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NIH Guidelines for the Laboratory Use of Chemical Carcinogens by National Institutes of Health (U.S.) Pdf

Author : Great Britain. Committee on Toxicity of Chemicals in Food, Consumer Products, and the Environment,Great Britain. Department of Health and Social Security
Publisher : Unknown
Page : 74 pages
File Size : 45,7 Mb
Release : 1982
Category : Toxicity testing
ISBN : UCBK:B000249518

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Guidelines for the Testing of Chemicals for Toxicity by Great Britain. Committee on Toxicity of Chemicals in Food, Consumer Products, and the Environment,Great Britain. Department of Health and Social Security Pdf

Author : OECD
Publisher : OECD Publishing
Page : 16 pages
File Size : 53,7 Mb
Release : 2018-06-27
Category : Electronic
ISBN : 9789264071209

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies by OECD Pdf

The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Comparative Toxicity of Naturally Occurring Carcinogens
Publisher : National Academies Press
Page : 433 pages
File Size : 50,5 Mb
Release : 1996-02-12
Category : Nature
ISBN : 9780309175715

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Carcinogens and Anticarcinogens in the Human Diet by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Comparative Toxicity of Naturally Occurring Carcinogens Pdf

Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.

Author : Marcel Castegnaro,Eric Brandfon Sansone
Publisher : Springer
Page : 118 pages
File Size : 43,7 Mb
Release : 1986
Category : Medical
ISBN : UOM:39015011178376

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Chemical Carcinogens by Marcel Castegnaro,Eric Brandfon Sansone Pdf

Author : National Cancer Institute (U.S.). Office of Research Safety
Publisher : Unknown
Page : 32 pages
File Size : 45,9 Mb
Release : 1975
Category : Cancer
ISBN : PURD:32754081179156

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National Cancer Institute Safety Standards for Research Involving Chemical Carcinogens by National Cancer Institute (U.S.). Office of Research Safety Pdf

Author : Kirk T. Kitchin
Publisher : CRC Press
Page : 918 pages
File Size : 49,7 Mb
Release : 2021-12-17
Category : Science
ISBN : 9781000105469

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Carcinogenicity by Kirk T. Kitchin Pdf

Offers comprehensive coverage of currently available cancer predictors, the most recent research on carcinogenicity, and the design and interpretation of carcinogenicity experiments. Presents mouse, rat, and human carcinogenicity data for the liver, kidney, breast, cervix, prostate, hematopoietic system, colon, skin, urinary bladder, mouth, stomach, thyroid, and pancreas.

Author : Organisation for Economic Co-operation and Development
Publisher : Organisation for Economic Co-operation and Development ; [Montréal : Renouf]
Page : 128 pages
File Size : 46,6 Mb
Release : 1981
Category : Chemical industry
ISBN : 9264122214

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OECD Guidelines for Testing of Chemicals by Organisation for Economic Co-operation and Development Pdf