Gut Microbiome Related Diseases And Therapies

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Gut Microbiome-Related Diseases and Therapies

Author : Maria Gazouli,George Theodoropoulos
Publisher : Springer Nature
Page : 328 pages
File Size : 49,9 Mb
Release : 2021-04-24
Category : Medical
ISBN : 9783030596422

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Gut Microbiome-Related Diseases and Therapies by Maria Gazouli,George Theodoropoulos Pdf

This book reviews recent knowledge of the role of gut microbiome in health and disease. It covers extensive topics for several diseases, including metabolic-related diseases, allergies, gastrointestinal diseases, psychiatric diseases, and cancer, while also discussing therapeutic approaches by microbiota modification. Comprehensive and cutting-edge, Gut Microbiome-Related Diseases and Therapies deepens a reader’s theoretical expertise in gut microbiome. Graduate and postdoctoral students, medical doctors, and biomedical researchers will benefit from this book.

The Interplay of Microbiome and Immune Response in Health and Diseases

Author : Gwendolyn Barcel´o-Coblijn,Amedeo Amedei
Publisher : MDPI
Page : 206 pages
File Size : 50,9 Mb
Release : 2019-11-06
Category : Medical
ISBN : 9783039216468

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The Interplay of Microbiome and Immune Response in Health and Diseases by Gwendolyn Barcel´o-Coblijn,Amedeo Amedei Pdf

[Increasing evidence suggests that microbiota and especially the gut microbiota (the microbes inhabiting the gut including bacteria, archaea, viruses, and fungi) plays a key role in human physiology and pathology. Recent findings indicate how dysbiosis—an imbalance in the composition and organization of microbial populations—could severely impact the development of different medical conditions (from metabolic to mood disorders), providing new insights into the comprehension of diverse diseases, such as IBD, obesity, asthma, autism, stroke, diabetes, and cancer. Given that microbial cells in the gut outnumber host cells, microbiota influences human physiology both functionally and structurally. Microbial metabolites bridge various—even distant—areas of the organism by way of the immune and hormone system. For instance, it is now clear that the mutual interaction between the gastrointestinal tract and the brain (gut–brain axis), often involves gut microbiota, indicating that the crosstalk between the organism and its microbial residents represents a fundamental aspect of both the establishment and maintenance of healthy conditions. Moreover, it is crucial to recognize that beyond the intestinal tract, microbiota populates other host organs and tissues (e.g., skin and oral mucosa). We have edited this eBook with the aim of publishing manuscripts focusing on the impact of microbiota in the development of different diseases and their associated treatments.]

The Gut Microbiome in Health and Disease

Author : Dirk Haller
Publisher : Springer
Page : 356 pages
File Size : 50,7 Mb
Release : 2018-07-27
Category : Medical
ISBN : 9783319905457

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The Gut Microbiome in Health and Disease by Dirk Haller Pdf

The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

Human Microbiota in Health and Disease

Author : Bryan Tungland
Publisher : Academic Press
Page : 680 pages
File Size : 44,9 Mb
Release : 2018-05-25
Category : Science
ISBN : 9780128146507

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Human Microbiota in Health and Disease by Bryan Tungland Pdf

Human Gut Microbiota in Health and Disease: From Pathogenesis to Therapy is a comprehensive discussion on all the aspects associated with the early colonization of gut microbiota, its development and maintenance, and its symbiotic relationship with the host in promoting health. Chapters illustrate the complex mechanisms and metabolic signaling pathways related to how the gut microbiota maintain proper regulation of glucose, lipid and energy homeostasis and immune response, all while mediating inflammatory processes involved in the etiology of many chronic disease conditions. With today's common use of pharmaceutical medicine in treating symptoms and frequent overuse of antibiotics in chronic disease within mainstream medical practice, our understanding of the etiological mechanisms of dysbiosis-induced chronic disease and natural approaches to prevention and potential cures for these diseases is of vital importance to overall human health. Details the complex relationship between human microbiota in the gut, oral cavity and skin as well as their colonization, development and impact of factors that influence the relationship Illustrates the mechanisms associated with dysbiosis-associated inflammation and its role in the onset and progression in chronic disease Provides the primary mechanisms and comprehensive scientific evidence for the use of dietary modification and pro- and prebiotics in preventing chronic disease

The Chemistry of Microbiomes

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Chemical Sciences Roundtable
Publisher : National Academies Press
Page : 133 pages
File Size : 52,5 Mb
Release : 2017-07-19
Category : Science
ISBN : 9780309458399

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The Chemistry of Microbiomes by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Chemical Sciences Roundtable Pdf

The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.

The Gut Microbiome

Author : Gyula Mozsik
Publisher : BoD – Books on Demand
Page : 114 pages
File Size : 54,6 Mb
Release : 2016-11-02
Category : Medical
ISBN : 9789535127505

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The Gut Microbiome by Gyula Mozsik Pdf

In the last decades, the importance of gut microbiome has been linked to medical research on different diseases. Developments of other medical disciplines (human clinical pharmacology, clinical nutrition and dietetics, everyday medical treatments of antibiotics, changes in nutritional inhabits in different countries) also called attention to study the changes in the gut microbiome. This book contains five excellent review chapters in the field of gut microbiome, written by researchers from the USA, Canada, China, and India. These chapters present a critical review about some clinically important changes in the gut microbiome in the development of some human diseases and therapeutic possibilities (liver disease, cardiovascular diseases, brain diseases, gastrointestinal diseases). The book brings to attention the essential role of gut microbiome in keeping our life healthy. This book is addressed to experts of microbiology, podiatrists, gastroenterologists, internists, nutritional experts, cardiologists, basic and clinical researchers, as well as experts in the field of food industry.

Microbiome in IBD: From Composition to Therapy

Author : Ruixin Zhu,Peijian He,Zhanju Liu,Ning-Ning Liu,Yinglei Miao,Chenggong Yu,Lixin Zhu
Publisher : Frontiers Media SA
Page : 130 pages
File Size : 55,6 Mb
Release : 2021-08-25
Category : Science
ISBN : 9782889712236

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Microbiome in IBD: From Composition to Therapy by Ruixin Zhu,Peijian He,Zhanju Liu,Ning-Ning Liu,Yinglei Miao,Chenggong Yu,Lixin Zhu Pdf

Bugs as Drugs

Author : Robert A. Britton,Patrice D. Cani
Publisher : John Wiley & Sons
Page : 514 pages
File Size : 46,7 Mb
Release : 2020-07-02
Category : Medical
ISBN : 9781555819705

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Bugs as Drugs by Robert A. Britton,Patrice D. Cani Pdf

Examining the enormous potential of microbiome manipulation to improve health Associations between the composition of the intestinal microbiome and many human diseases, including inflammatory bowel disease, cardiovascular disease, metabolic disorders, and cancer, have been elegantly described in the past decade. Now, whole-genome sequencing, bioinformatics, and precision gene-editing techniques are being combined with centuries-old therapies, such as fecal microbiota transplantation, to translate current research into new diagnostics and therapeutics to treat complex diseases. Bugs as Drugs provides a much-needed overview of microbes in therapies and will serve as an excellent resource for scientists and clinicians as they carry out research and clinical studies on investigating the roles the microbiota plays in health and disease. In Bugs as Drugs, editors Robert A. Britton and Patrice D. Cani have assembled a fascinating collection of reviews that chart the history, current efforts, and future prospects of using microorganisms to fight disease and improve health. Sections cover traditional uses of probiotics, next-generation microbial therapeutics, controlling infectious diseases, and indirect strategies for manipulating the host microbiome. Topics presented include: How well-established probiotics support and improve host health by improving the composition of the intestinal microbiota of the host and by modulating the host immune response. The use of gene editing and recombinant DNA techniques to create tailored probiotics and to characterize next-generation beneficial microbes. For example, engineering that improves the anti-inflammatory profile of probiotics can reduce the number of colonic polyps formed, and lactobacilli can be transformed into targeted delivery systems carrying therapeutic proteins or bioengineered bacteriophage. The association of specific microbiota composition with colorectal cancer, liver diseases, osteoporosis, and inflammatory bowel disease. The gut microbiota has been proposed to serve as an organ involved in regulation of inflammation, immune function, and energy homeostasis. Fecal microbiota transplantation as a promising treatment for numerous diseases beyond C. difficile infection. Practical considerations for using fecal microbiota transplantation are provided, while it is acknowledged that more high-quality evidence is needed to ascertain the importance of strain specificity in positive treatment outcomes. Because systems biology approaches and synthetic engineering of microbes are now high-throughput and cost-effective, a much wider range of therapeutic possibilities can be explored and vetted.

Gut Microbiota in the Occurrence, Development and Treatment of Gut-Brain Disorders

Author : Zongxin Ling,Qixiao Zhai,Liwei Xie,Tingtao Chen
Publisher : Frontiers Media SA
Page : 127 pages
File Size : 45,9 Mb
Release : 2022-01-31
Category : Science
ISBN : 9782889742394

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Gut Microbiota in the Occurrence, Development and Treatment of Gut-Brain Disorders by Zongxin Ling,Qixiao Zhai,Liwei Xie,Tingtao Chen Pdf

Microbiome Therapeutics

Author : Nar Singh Chauhan,Suneel Kumar
Publisher : Elsevier
Page : 530 pages
File Size : 51,6 Mb
Release : 2023-05-17
Category : Science
ISBN : 9780323993371

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Microbiome Therapeutics by Nar Singh Chauhan,Suneel Kumar Pdf

Microbiome Therapeutics: Personalized Therapy Beyond Conventional Approaches addresses the current knowledge and landscape of microbiome therapeutics, providing an overview of existing applications in health and disease as well as potential future directions of microbiome modulations and subsequent translation to the global industry and market. This important reference provides the most current status of microbiome therapeutics as well as possible future perspectives through coverage of topics including the application of microbiome therapeutics; various additive, subtractive and modulatory approaches; microbiome composition of health and diseases, insights into live bio-therapeutics and the clinical data supporting their efficacy. Case studies are provided throughout the book to further define, describe and evaluate microbiome therapeutics success and failure. Provides chapters focused on illness types to address the potential of microbiome therapeutics in several significant disorders Offers human gut microbiome explorations that have enriched the understanding of microbiome colonization, maturation, and dysbiosis in health and disease subsets Addresses important concepts like economic potential in the global therapeutics market as well as ethical, technical, and regulatory aspects

Microbiome in Human Health and Disease

Author : Pallaval Veera Bramhachari
Publisher : Springer Nature
Page : 306 pages
File Size : 55,7 Mb
Release : 2021-10-18
Category : Medical
ISBN : 9789811631566

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Microbiome in Human Health and Disease by Pallaval Veera Bramhachari Pdf

The book provides an overview on how the microbiome contributes to human health and disease. The microbiome has also become a burgeoning field of research in medicine, agriculture & environment. The readers will obtain profound knowledge on the connection between intestinal microbiota and immune defense systems, medicine, agriculture & environment. The book may address several researchers, clinicians and scholars working in biomedicine, microbiology and immunology. The application of new technologies has no doubt revolutionized the research initiatives providing new insights into the dynamics of these complex microbial communities and their role in medicine, agriculture & environment shall be more emphasized. Drawing on broad range concepts of disciplines and model systems, this book primarily provides a conceptual framework for understanding these human-microbe, animal-microbe & plant-microbe, interactions while shedding critical light on the scientific challenges that lie ahead. Furthermore this book explains why microbiome research demands a creative and interdisciplinary thinking—the capacity to combine microbiology with human, animal and plant physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science.This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet in a typical immune system, and have contributed to animal and plant diversification over long evolutionary timescales. Also this book explains why microbiome research presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for human health and new strategies.

Microbial Endocrinology

Author : Mark Lyte,Primrose P.E. Freestone
Publisher : Springer Science & Business Media
Page : 325 pages
File Size : 43,9 Mb
Release : 2010-04-06
Category : Medical
ISBN : 9781441955760

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Microbial Endocrinology by Mark Lyte,Primrose P.E. Freestone Pdf

Microbial endocrinology represents a newly emerging interdisciplinary field that is formed by the intersection of the fields of neurobiology and microbiology. This book will introduce a new perspective to the current understanding not only of the factors that mediate the ability of microbes to cause disease, but also to the mechanisms that maintain normal homeostasis. The discovery that microbes can directly respond to neuroendocrine hormones, as evidenced by increased growth and production of virulence-associated factors, provides for a new framework with which to investigate how microorganisms interface not only with vertebrates, but also with invertebrates and even plants. The reader will learn that the neuroendocrine hormones that one most commonly associates with mammals are actually found throughout the plant, insect and microbial communities to an extent that will undoubtedly surprise many, and most importantly, how interactions between microbes and neuroendocrine hormones can influence the pathophysiology of infectious disease.

The Gut-Brain Axis

Author : Niall Hyland,Catherine Stanton
Publisher : Elsevier
Page : 544 pages
File Size : 46,5 Mb
Release : 2023-12-15
Category : Medical
ISBN : 9780323983020

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The Gut-Brain Axis by Niall Hyland,Catherine Stanton Pdf

The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota, Second Edition presents the most advances on how the gut microbiome influences central nervous system and brain function introduced in the first edition. The book also describes how environmental influences which affect the microbiota, including, diet, exercise, and early-life, impact on the gut-brain axis. The second edition contains new chapters on metabolomics and the gut-brain-axis; dietary factors in the maintenance of a healthy brain ; the role of gut microbes in neurodegenerative disorders; the link between exercise and the gut-brain-axis; and infant Nutrition, the microbiome and neurodevelopment. In addition, the second edition presents coverage of mechanisms underlying neurological disease; approaches to investigate the role of the microbiome in brain and behavior, and 'next generation' probiotics and prebiotics. The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota, Second Edition continues to be the “go-to resource for further exploration of the microbiota. Includes new chapters focused on metabolomics and the gut-brain axis; dietary polyphenols to maintain healthier brain measures and cognitive function; the role of gut microbes in Parkinson’s Disease; the microbiota-gut-brain axis in psychosis; exploration of exercise and the gut-brain axis; and coverage of pediatric nutrition Updated chapters reflect on the most recent advances on the role of the microbiome and gut-brain axis in early-life, aging, cognition, metabolism, neurodevelopmental disorders, as well as on the enteric nervous system Addresses the role of diet and the gut-brain axis across several chapters with unique author insights and perspectives Examines common mechanisms and pathways by which the microbiota may influence brain and behavior Discusses strategies to explore the contribution of the microbiome to the gut-brain axis; methods to enhance therapeutic strategies targeted toward the microbiota; and presents a case study demonstrating a rational screening approach to increase translational success

Health and the Gut

Author : William Olds
Publisher : CRC Press
Page : 410 pages
File Size : 43,8 Mb
Release : 2014-08-04
Category : Medical
ISBN : 9781498701266

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Health and the Gut by William Olds Pdf

This title includes a number of Open Access chapters. The study of the intestinal ecosystem of bacteria in the human gut—the gut microbiome—is a new field that is rapidly evolving. This book serves as an introduction to some of the new and exciting research that is being done in this field. Included are chapters that examine the following: • Gut microbiome’s roles in the pathogenesis of obesity and autoimmune disease • The effect of nutrition on the richness of the microbial community • The stability of the microbiome to various stressors • Emerging ways to diagnose diseases using the microbiome • Exciting prospects for using these microbes to cure disease This easily accessible reference volume offers a comprehensive guide to this relatively new field of study. Edited by a researcher from Yale University, Health and the Gut: The Emerging Role of Intestinal Microbiota in Disease and Therapeutics is an authoritative and easy-to-use reference, ideal for both researchers in the field and those who wish to gain more information about the impact of gut microbiota on human health.

Health and the Gut

Author : William Olds
Publisher : Apple Academic Press
Page : 0 pages
File Size : 53,8 Mb
Release : 2021-03-31
Category : Intestines
ISBN : 1774632047

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Health and the Gut by William Olds Pdf

This title includes a number of Open Access chapters. The study of the intestinal ecosystem of bacteria in the human gut-the gut microbiome-is a new field that is rapidly evolving. This book serves as an introduction to some of the new and exciting research that is being done in this field. Included are chapters that examine the following: - Gut microbiome's roles in the pathogenesis of obesity and autoimmune disease - The effect of nutrition on the richness of the microbial community - The stability of the microbiome to various stressors - Emerging ways to diagnose diseases using the microbiome - Exciting prospects for using these microbes to cure disease This easily accessible reference volume offers a comprehensive guide to this relatively new field of study. Edited by a researcher from Yale University, Health and the Gut: The Emerging Role of Intestinal Microbiota in Disease and Therapeutics is an authoritative and easy-to-use reference, ideal for both researchers in the field and those who wish to gain more information about the impact of gut microbiota on human health.