Handbook Of Brain Tumor Chemotherapy Molecular Therapeutics And Immunotherapy

Author : Herbert B. Newton
Publisher : Academic Press
Page : 848 pages
File Size : 48,7 Mb
Release : 2018-03-28
Category : Medical
ISBN : 9780128121016

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Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy by Herbert B. Newton Pdf

Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy, Second Edition, provides a comprehensive overview of the molecular methodologies in the neuro-oncology field. There have been profound changes in the landscape of approaches to brain tumor therapy since the first edition—mainly in the areas of molecular biology and molecular therapeutics, as well as in the maturation of immunotherapy approaches (e.g., vaccines). This updated edition has a new, primary focus on multidisciplinary molecular methods, and is broadened to include the latest cutting-edge molecular biology, therapeutics, immunobiology and immunotherapy approaches. As the first comprehensive book to address the molecular research into these concepts, users will find it to be an invaluable resource on the topics discussed. Provides the most up-to-date information regarding conventional forms of cytotoxic chemotherapy, as well as the basic science and clinical application of molecular therapeutics for the treatment of brain tumors Broadly appeals to anyone interested in neuro-oncology and the treatment of brain tumors Features updated chapters on molecular biology, molecular therapeutics, maturation of immunotherapy approaches, and a focus on multidisciplinary molecular methods Includes a new section on the basic science of immunology, as well as thorough updates on the use of vaccine technology and immunotherapy for the treatment of brain tumors

Author : Herbert B. Newton
Publisher : Elsevier
Page : 586 pages
File Size : 51,5 Mb
Release : 2005-12-19
Category : Medical
ISBN : 008045593X

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Handbook of Brain Tumor Chemotherapy by Herbert B. Newton Pdf

Treatment of patients with a brain tumor remains one of the most challenging and difficult areas of modern oncology. Recent advances in the molecular biology of these neoplasms have improved our understanding of the malignant phenotype and have lead to the development of novel forms of chemotherapy, including “targeted agents. The Handbook of Brain Tumor Chemotherapy reviews the state-of-the-art of chemotherapy development and clinical treatment of patients with this devastating disease. Handbook of Brain Tumor Chemotherapy offers a unique cutting-edge compendium of basic science and clinical information on the subject of brain tumor chemotherapy, reviewing what has been accomplished thus far and how the field will continue to evolve with the development of more specific and efficacious chemotherapeutic agents. This book represents the most complete single-volume resource available for information on the subject of brain tumor chemotherapy. Provides the most up to date information regarding conventional forms of cytotoxic chemotherapy, as well as the basic science and clinical application of molecular therapeutics, for the treatment of brain tumors Broadly appeals to anyone interested in the field of Neuro-Oncology and in the treatment of patients with brain tumors Useful to clinicians interested in a thorough overview of the use of chemotherapy in patients with a broad range of brain tumors as well as serving as a source of background information to basic scientists and pharmaceutical researchers with an interest in the molecular therapeutics of brain tumors

Author : Linda M. Liau,Donald P. Becker,Timothy F. Cloughesy,Darell D. Bigner
Publisher : Springer Science & Business Media
Page : 369 pages
File Size : 54,5 Mb
Release : 2000-11-10
Category : Medical
ISBN : 9781592590353

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Brain Tumor Immunotherapy by Linda M. Liau,Donald P. Becker,Timothy F. Cloughesy,Darell D. Bigner Pdf

An authoritative panel of researchers and clinicians critically reviews the entire field to provide a comprehensive guide to modern brain tumor immunotherapy and thereby enhance future research in this area. The contributors detail many of the key laboratory experiments and clinical protocols that are currently being investigated, integrate the available information from previous and ongoing research, and help define the current status of the field. Topics range from adoptive cellular and antibody-mediated immunotherapy of brain tumors to tumor vaccines and related strategies, and include many vanguard experimental strategies and immunological techniques for studying brain tumor immunotherapy. Cutting-edge and comprehensive, Brain Tumor Immunotherapy brings together all the important recent advances in our understanding of central nervous system tumor immunology and illustrates in powerful detail the many new applications now harnessing the immune response for brain tumor therapeutics.

Author : Herbert B. Newton
Publisher : Academic Press
Page : 1022 pages
File Size : 55,7 Mb
Release : 2022-08-21
Category : Medical
ISBN : 9780128229958

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Handbook of Neuro-Oncology Neuroimaging by Herbert B. Newton Pdf

With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this third edition of the Handbook of Neuro-Oncology Neuroimaging is very relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuroimaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the second edition, and in addition features several new important chapters covering diverse topics such as imaging for the use of Laser Interstitial Thermal Therapy, advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. Sections first overview neuro-oncological disorders before delving into the physics and basic science of neuroimaging and great focus on CT and MRI. The book then focuses on advances in the neuroimaging of brain tumors and neuroimaging of specific tumor types. There is also discussion of neuroimaging of other neuro-oncological syndromes. This book will serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology. Summarizes translational research on brain imaging for brain tumors Discusses limitations of neuroimaging for diagnosis and treatment Presents advanced imaging technologies, including CT, MRI, and PET Contains new coverage on Laser Interstitial Thermal Therapy, radiation therapy, clinical trials, and more

Author : Roland T. Skeel
Publisher : Lippincott Williams & Wilkins
Page : 838 pages
File Size : 51,9 Mb
Release : 2007
Category : Medical
ISBN : 0781765315

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Handbook of Cancer Chemotherapy by Roland T. Skeel Pdf

The Seventh Edition of this pocket reference is a practical, disease-focused guide to the best current medical practice in cancer chemotherapy. In easy-to-follow outline format, the book provides complete coverage of the principles of rational chemotherapy, the chemotherapeutic and biotherapeutic agents available, the treatment of specific cancers, and selected aspects of supportive care. Emphasis is on the indications, dosage/schedule, potential toxicities, and safe administration of the drugs and their use in treating specific malignancies. This edition describes seventeen new chemotherapeutic agents, with particular attention to molecular targeted agents. Updated chapters on individual cancers and supportive care provide state-of-the-art treatment recommendations.

Author : Allan H. Friedman
Publisher : Cambridge University Press
Page : 237 pages
File Size : 50,8 Mb
Release : 2016-03-31
Category : Medical
ISBN : 9781107065970

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The Duke Glioma Handbook by Allan H. Friedman Pdf

Provides a summary of glioma biology, genetics and management, based on the world-leading Duke University Preston Robert Tisch Brain Tumor Center program.

Author : Jahangir Moini,Nicholas Avgeropoulos,Mohtashem Samsam
Publisher : Academic Press
Page : 554 pages
File Size : 53,7 Mb
Release : 2021-04-09
Category : Medical
ISBN : 9780128217559

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Epidemiology of Brain and Spinal Tumors by Jahangir Moini,Nicholas Avgeropoulos,Mohtashem Samsam Pdf

Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors. Provides the most up-to-date information surrounding the epidemiology, biology and imaging techniques for brain and spinal tumors, including CT, MRI, PET, and others Includes full color figures, photos, tables, graphs and radioimaging Contains information that will be valuable to anyone interested in the field of neurooncology and the treatment of patients with brain and spinal tumors Serves as a source of background information for basic scientists and pharmaceutical researchers who have an interest in imaging and treatment

Author : D. Joanne Lynn,Herbert B. Newton,Alexander D. Rae-Grant
Publisher : Lippincott Williams & Wilkins
Page : 485 pages
File Size : 46,9 Mb
Release : 2012
Category : Medical
ISBN : 9781451100129

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The 5-Minute Neurology Consult by D. Joanne Lynn,Herbert B. Newton,Alexander D. Rae-Grant Pdf

This volume in the 5-Minute Consult series focuses on neurological diseaes and disorders, as well as key symptoms, signs, and tests. Dozens of noted authorities provide tightly organized, practical guidance. Using the famous two-page layout and outline format of The 5-Minute Consult Series, the book provides instant access to clinically-oriented, must-have information on all disorders of the nervous system. Each disease is covered in a consistent, easy-to-follow format: basics (including signs and symptoms), diagnosis, treatment, medications, follow-up, and miscellaneous considerations (including diseases with similar characteristics, pregnancy, synonyms, and ICD coding).

Author : Herbert B. Newton,Mark G. Malkin
Publisher : Academic Press
Page : 680 pages
File Size : 52,7 Mb
Release : 2022-03-15
Category : Medical
ISBN : 9780128219775

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Neurological Complications of Systemic Cancer and Antineoplastic Therapy by Herbert B. Newton,Mark G. Malkin Pdf

Neurological Complications of Systematic Cancer and Antineoplastic Therapy, Second Edition provides an expanded, updated and in-depth review of common manifestations related to neurology that occur in patients with systemic cancer. These include brain metastases, spinal cord compression, cerebrovascular events, and leptomeningeal disease. The book also discusses neurological complications related to treatments such as radiation and chemotherapy and is an essential reference for the practicing neurologist and oncologist. Sections in this new release cover the pathophysiology and molecular biology of cancer and the metastatic phenotype, Metastatic spread to cranial and peripheral nerves and brachial and lumbosacral plexuses, Metabolic and nutritional disorders, CNS infections, Neurological complications of immunotherapy and bone marrow transplants, Neurological complications of new molecular agents and immuno-modulatory drugs, and more. Summarizes the neurologic effects of both cancer and cancer treatment Provides scientific and clinical information relevant to research and treatment Identifies neurological complications by tumor type and tumor therapy Covers GI, lung, breast, gynecological, head and neck cancers, and more Includes radiotherapy, chemotherapy, immunotherapy, and new drugs Contains melanoma, lymphoma, sarcoma, myeloma, leukemia, and more

Author : Jahangir Moini,Nicholas G. Avgeropoulos,Craig Badolato
Publisher : John Wiley & Sons
Page : 676 pages
File Size : 40,6 Mb
Release : 2022-03-22
Category : Medical
ISBN : 9781119817185

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Global Epidemiology of Cancer by Jahangir Moini,Nicholas G. Avgeropoulos,Craig Badolato Pdf

GLOBAL EPIDEMIOLOGY OF CANCER Cancer is the second highest cause of death in the United States, and a leading cause of death globally. Our goals are to discuss the global epidemiology of various cancers, with detailed information on their prevalence, incidence, and clinical considerations. Epidemiology is the key to understanding the mortality and morbidity of cancer, and how we can prevent, diagnose, and treat the disease. Prevention of cancer is essential for saving lives. Prevalence and incidence of cancer are key factors that each government and population must be aware of. Advances in the study of cancer occur on a regular basis, and this book provides the latest insights about relationships between the disease and stem cells, tumorigenesis, molecular interactions, pathways, channels, and immunity. Global Epidemiology of Cancer: Diagnosis and Treatment meets the needs of readers by providing current information about epidemiology (including molecular epidemiology), diagnosis, and treatment. Providing logical, step-by-step information on various cancers, this book consolidates all of the most up-to-date information and data from verified studies on all different types of cancers in the United States and throughout the world. Chapters are presented so that each includes an overview, clinical manifestations, epidemiology, pathophysiology, etiology and risk factors, diagnosis, treatment, prevention, and prognosis. Global Epidemiology of Cancer: Diagnosis and Treatment will be invaluable to graduate and postgraduate students, including medical students; nurses; physician assistants; residents in oncology; public health students and allied health students.

Author : Anonim
Publisher : Demos Medical Publishing
Page : 750 pages
File Size : 51,6 Mb
Release : 2010-10-21
Category : Medical
ISBN : 9781617050145

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Principles & Practice of Neuro-Oncology by Anonim Pdf

Neuro-oncologic (brain and spine) cancers account for 19,000 new cases and 13,000 deaths per year. The early and proper diagnosis of these virulent cancers is critical to patient outcomes and diagnosis and treatment strategies are continually evolving. The multidisciplinary team that manages these patients involves medical and radiation oncology, neurosurgery, neuroimaging, nurses and therapists. Principles and Practices of Neuro-Oncology establishes a new gold standard in care through a comprehensive, multidisciplinary text covering all aspects of neuro-oncology. Six major sections cover all topics related to epidemiology and etiology, molecular biology, clinical features and supportive care, imaging, neuroanatomy and neurosurgery, medical oncology and targeted therapies, and radiation oncology for adult and pediatric cancers. Expert contributors from multiple disciplines provide detailed and in-depth discussions of the entire field of neuro-oncology including histopathologic harmonization, neurosurgical techniques, quality of life and cognitive functions, and therapeutic changes in terms of combined modality treatments, advanced radiation techniques, the advent of new drugs, especially targeted agents, and the tantalizing early promise of personalized therapeutic approaches. With contributions from over 180 authors, numerous diagrams, illustrations and tables, and a 48 page color section, Principles and Practice of Neuro-Oncology reflects the breadth and depth of this multi-faceted specialty.

Author : Mizuki Nishino
Publisher : Springer Nature
Page : 266 pages
File Size : 40,9 Mb
Release : 2020-01-07
Category : Medical
ISBN : 9783030311711

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Therapy Response Imaging in Oncology by Mizuki Nishino Pdf

This book is a detailed guide to therapy response imaging in cancer patients that fully takes into account the revolutionary progress and paradigm shift in treatment approaches for advanced disease. The opening chapters describe the role of imaging as a “common language” for tumor response evaluation in oncology and address challenges and strategies in the era of precision cancer therapy and cancer immunotherapy. Practical pitfalls are discussed, with emphasis on the importance of approaching cancer as a systemic disease and the need for increased awareness of drug toxicity due to novel therapies. Therapy response imaging in a wide range of cancer types is then comprehensively described and illustrated, using a disease-specific approach. A concluding section focuses on emerging approaches and future directions, including radiomics/radiogenomics, co-clinical imaging, and molecular and functional imaging. Therapy Response Imaging in Oncology will be of high value for radiologists, nuclear medicine physicians, and oncologists. It will also be of interest to cancer care providers and oncology trial investigators.

Author : Bin Ren,Xiaofeng Yang,Ramani Ramchandran
Publisher : Frontiers Media SA
Page : 332 pages
File Size : 48,8 Mb
Release : 2022-02-02
Category : Science
ISBN : 9782889742523

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Molecular Mechanisms and Signaling in Endothelial Cell Biology and Vascular Heterogeneity by Bin Ren,Xiaofeng Yang,Ramani Ramchandran Pdf

Author : Ben Atchison,Diane Dirette
Publisher : Lippincott Williams & Wilkins
Page : 1218 pages
File Size : 46,7 Mb
Release : 2023-04-03
Category : Medical
ISBN : 9781975215583

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Conditions in Occupational Therapy by Ben Atchison,Diane Dirette Pdf

This updated 6th Edition is fully aligned with the most current DSM-5 and Occupational Therapy Practice Framework, 4th Edition, and adds new chapters reflecting recent advances in the management of infectious diseases, general deconditioning, musculoskeletal pain, amputations, and sickle cell anemia. Each chapter follows a consistent format, presenting an opening case followed by descriptions and definitions, etiology, incidence and prevalence, signs and symptoms, diagnosis, course and prognosis, medical/surgical management, impact on occupational performance, and two case illustrations. Rounded out with robust instructor resources and new full-color imagery, this bestselling resource is an essential tool for today’s occupational therapy and occupational therapy assistant students.

Author : Russell R. Lonser,Malisa Sarntinoranont,Kristof Bankiewicz
Publisher : Academic Press
Page : 556 pages
File Size : 41,8 Mb
Release : 2019-06-25
Category : Medical
ISBN : 9780128139981

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Nervous System Drug Delivery by Russell R. Lonser,Malisa Sarntinoranont,Kristof Bankiewicz Pdf

Nervous System Drug Delivery: Principles and Practice helps users understand the nervous system physiology affecting drug delivery, the principles that underlie various drug delivery methods, and the appropriate application of drug delivery methods for drug- and disease-specific treatments. Researchers developing nervous system putative therapeutic agents will use this book to optimize drug delivery during preclinical assessment and to prepare for regulatory advancement of new agents. Clinicians will gain direct insights into pathophysiologic alterations that impact drug delivery and students and trainees will find this a critical resource for understanding and applying nervous system drug delivery techniques. Offers an up-to-date, comprehensive resource on drug delivery to the nervous system Provides a bridge for understanding across nervous system delivery-related physiology, drug delivery principles. and the methodologies that underlie the various methods of drug distribution (with clinical application) Written for a broad audience of researchers, clinicians and advanced graduate students in neuroscience, neurology, neurosurgery, pharmacology, radiology and psychiatry