Handbook Of Systems Biology

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Handbook of Systems Biology

Author : Marian Walhout,Marc Vidal,Job Dekker
Publisher : Academic Press
Page : 552 pages
File Size : 47,8 Mb
Release : 2012-12-31
Category : Science
ISBN : 9780123859457

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Handbook of Systems Biology by Marian Walhout,Marc Vidal,Job Dekker Pdf

This book provides an entry point into Systems Biology for researchers in genetics, molecular biology, cell biology, microbiology and biomedical science to understand the key concepts to expanding their work. Chapters organized around broader themes of Organelles and Organisms, Systems Properties of Biological Processes, Cellular Networks, and Systems Biology and Disease discuss the development of concepts, the current applications, and the future prospects. Emphasis is placed on concepts and insights into the multi-disciplinary nature of the field as well as the importance of systems biology in human biological research. Technology, being an extremely important aspect of scientific progress overall, and in the creation of new fields in particular, is discussed in 'boxes' within each chapter to relate to appropriate topics. 2013 Honorable Mention for Single Volume Reference in Science from the Association of American Publishers' PROSE Awards Emphasizes the interdisciplinary nature of systems biology with contributions from leaders in a variety of disciplines Includes the latest research developments in human and animal models to assist with translational research Presents biological and computational aspects of the science side-by-side to facilitate collaboration between computational and biological researchers

Handbook of Statistical Systems Biology

Author : Michael Stumpf,David J. Balding,Mark Girolami
Publisher : John Wiley & Sons
Page : 624 pages
File Size : 55,6 Mb
Release : 2011-09-09
Category : Science
ISBN : 9781119952046

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Handbook of Statistical Systems Biology by Michael Stumpf,David J. Balding,Mark Girolami Pdf

Systems Biology is now entering a mature phase in which the key issues are characterising uncertainty and stochastic effects in mathematical models of biological systems. The area is moving towards a full statistical analysis and probabilistic reasoning over the inferences that can be made from mathematical models. This handbook presents a comprehensive guide to the discipline for practitioners and educators, in providing a full and detailed treatment of these important and emerging subjects. Leading experts in systems biology and statistics have come together to provide insight in to the major ideas in the field, and in particular methods of specifying and fitting models, and estimating the unknown parameters. This book: Provides a comprehensive account of inference techniques in systems biology. Introduces classical and Bayesian statistical methods for complex systems. Explores networks and graphical modeling as well as a wide range of statistical models for dynamical systems. Discusses various applications for statistical systems biology, such as gene regulation and signal transduction. Features statistical data analysis on numerous technologies, including metabolic and transcriptomic technologies. Presents an in-depth presentation of reverse engineering approaches. Provides colour illustrations to explain key concepts. This handbook will be a key resource for researchers practising systems biology, and those requiring a comprehensive overview of this important field.

Compact Handbook of Computational Biology

Author : A.K. Konopka,M. James C. Crabbe
Publisher : CRC Press
Page : 572 pages
File Size : 51,8 Mb
Release : 2004-08-30
Category : Mathematics
ISBN : 9780203021415

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Compact Handbook of Computational Biology by A.K. Konopka,M. James C. Crabbe Pdf

The assimilation of computational methods into the life sciences has played an important role in advancing biological research. From sequencing genomes to discovering motifs in large collections of functionally equivalent sequences of nucleic acids and proteins, the value of powerful computational tools has become abundantly clear. The Compact Hand

Handbook of Research on Computational and Systems Biology

Author : Limin Angela Liu,Dongqing Wei,Yixue Li
Publisher : IGI Global
Page : 0 pages
File Size : 42,9 Mb
Release : 2011
Category : Computers
ISBN : 1609604911

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Handbook of Research on Computational and Systems Biology by Limin Angela Liu,Dongqing Wei,Yixue Li Pdf

"This book offers information on the state-of-the-art development in the fields of computational biology and systems biology, presenting methods, tools, and applications of these fields by many leading experts around the globe"--Provided by publisher.

Handbook of Computational Molecular Biology

Author : Srinivas Aluru
Publisher : CRC Press
Page : 1108 pages
File Size : 46,6 Mb
Release : 2005-12-21
Category : Computers
ISBN : 9781420036275

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Handbook of Computational Molecular Biology by Srinivas Aluru Pdf

The enormous complexity of biological systems at the molecular level must be answered with powerful computational methods. Computational biology is a young field, but has seen rapid growth and advancement over the past few decades. Surveying the progress made in this multidisciplinary field, the Handbook of Computational Molecular Biology of

Handbook of Research on Systems Biology Applications in Medicine

Author : Daskalaki, Andriani
Publisher : IGI Global
Page : 982 pages
File Size : 43,8 Mb
Release : 2008-11-30
Category : Technology & Engineering
ISBN : 9781605660776

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Handbook of Research on Systems Biology Applications in Medicine by Daskalaki, Andriani Pdf

"This book highlights the use of systems approaches including genomic, cellular, proteomic, metabolomic, bioinformatics, molecular, and biochemical, to address fundamental questions in complex diseases like cancer diabetes but also in ageing"--Provided by publisher.

Synthetic Biology Handbook

Author : Darren N. Nesbeth
Publisher : CRC Press
Page : 328 pages
File Size : 44,9 Mb
Release : 2016-04-06
Category : Medical
ISBN : 9781466568488

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Synthetic Biology Handbook by Darren N. Nesbeth Pdf

The Synthetic Biology Handbook explains the major goals of the field of synthetic biology and presents the technical details of the latest advances made in achieving those goals. Offering a comprehensive overview of the current areas of focus in synthetic biology, this handbook:Explores the standardisation of classic molecular bioscience approaches

Handbook of the Biology of Aging

Author : Matt Kaeberlein,George Martin
Publisher : Academic Press
Page : 576 pages
File Size : 51,7 Mb
Release : 2015-08-20
Category : Medical
ISBN : 9780124116207

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Handbook of the Biology of Aging by Matt Kaeberlein,George Martin Pdf

Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of ‘big data’ approaches in the biological sciences, presenting new strategies to analyze, interpret, and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and the metabolomics methodologies applied to aging related problems. The book includes discussions on longevity pathways and interventions that modulate aging, innovative new tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, new strategies to pharmacologically modulate the mTOR pathway to delay aging, the importance of sirtuins and the hypoxic response in aging, and how various pathways interact within the context of aging as a complex genetic trait, amongst others. Covers the key areas in biological gerontology research in one volume, with an 80% update from the previous edition Edited by Matt Kaeberlein and George Martin, highly respected voices and researchers within the biology of aging discipline Assists basic researchers in keeping abreast of research and clinical findings outside their subdiscipline Presents information that will help medical, behavioral, and social gerontologists in understanding what basic scientists and clinicians are discovering New chapters on genetics, evolutionary biology, bone aging, and epigenetic control Provides a close examination of the diverse research being conducted today in the study of the biology of aging, detailing recent breakthroughs and potential new directions

Handbook on Biological Networks

Author : Stefano Boccaletti,Vito Latora,Yamir Moreno
Publisher : World Scientific
Page : 465 pages
File Size : 50,6 Mb
Release : 2010
Category : Science
ISBN : 9789812838797

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Handbook on Biological Networks by Stefano Boccaletti,Vito Latora,Yamir Moreno Pdf

Networked systems are all around us. The accumulated evidence of systems as complex as a cell cannot be fully understood by studying only their isolated constituents, giving rise to a new area of interest in research ? the study of complex networks. In a broad sense, biological networks have been one of the most studied networks, and the field has benefited from many important contributions. By understanding and modeling the structure of a biological network, a better perception of its dynamical and functional behavior is to be expected. This unique book compiles the most relevant results and novel insights provided by network theory in the biological sciences, ranging from the structure and dynamics of the brain to cellular and protein networks and to population-level biology.

Dynamics of Biological Systems

Author : Michael Small
Publisher : CRC Press
Page : 286 pages
File Size : 46,5 Mb
Release : 2011-08-25
Category : Mathematics
ISBN : 9781439853368

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Dynamics of Biological Systems by Michael Small Pdf

From the spontaneous rapid firing of cortical neurons to the spatial diffusion of disease epidemics, biological systems exhibit rich dynamic behaviour over a vast range of time and space scales. Unifying many of these diverse phenomena, Dynamics of Biological Systems provides the computational and mathematical platform from which to understand the underlying processes of the phenomena. Through an extensive tour of various biological systems, the text introduces computational methods for simulating spatial diffusion processes in excitable media, such as the human heart, as well as mathematical tools for dealing with systems of nonlinear ordinary and partial differential equations, such as neuronal activation and disease diffusion. The mathematical models and computer simulations offer insight into the dynamics of temporal and spatial biological systems, including cardiac pacemakers, artificial electrical defibrillation, pandemics, pattern formation, flocking behaviour, the interaction of autonomous agents, and hierarchical and structured network topologies. Tools from complex systems and complex networks are also presented for dealing with real phenomenological systems. With exercises and projects in each chapter, this classroom-tested text shows students how to apply a variety of mathematical and computational techniques to model and analyze the temporal and spatial phenomena of biological systems. MATLAB® implementations of algorithms and case studies are available on the author’s website.

Handbook of Systems Biology

Author : Alexis White
Publisher : Unknown
Page : 207 pages
File Size : 44,9 Mb
Release : 2019-06-20
Category : Electronic
ISBN : 1641161434

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Handbook of Systems Biology by Alexis White Pdf

Systems biology is an interdisciplinary field of science that is concerned with the computational and mathematical modeling of biological systems which are complex in nature. The field strives to model and discover properties of cells, tissues and organisms functioning as a system. These involve metabolic networks and cell signaling networks. Some associated disciplines of system biology are phenomics, genomics, epigenetics, proteomics, biomics, etc. Systems biology is an upcoming field of science that has undergone rapid development over the past few decades. This book covers in detail some existing theories and innovative concepts revolving around systems biology. It consists of contributions made by international experts. It is a vital tool for all researching and studying this field.

Systems Biology

Author : Bernhard Palsson
Publisher : Cambridge University Press
Page : 551 pages
File Size : 40,9 Mb
Release : 2015-01-26
Category : Medical
ISBN : 9781107038851

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Systems Biology by Bernhard Palsson Pdf

The first comprehensive single-authored textbook on genome-scale models and the bottom-up approach to systems biology.

An Introduction to Computational Systems Biology

Author : Karthik Raman
Publisher : CRC Press
Page : 359 pages
File Size : 46,7 Mb
Release : 2021-05-30
Category : Computers
ISBN : 9780429944529

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An Introduction to Computational Systems Biology by Karthik Raman Pdf

Emphasises a hands-on approach to modelling Strong emphasis on coding and software tools for systems biology Covers the entire spectrum of modelling, from static networks, to dynamic models Thoughtful exercises to test and enable student understanding of concepts Current chapters on exciting new developments like whole-cell modelling and community modelling

The Handbook of Communication Science and Biology

Author : Kory Floyd,René Weber
Publisher : Routledge
Page : 525 pages
File Size : 49,5 Mb
Release : 2020-05-07
Category : Language Arts & Disciplines
ISBN : 9781351235570

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The Handbook of Communication Science and Biology by Kory Floyd,René Weber Pdf

The Handbook of Communication Science and Biology charts the state of the art in the field, describing relevant areas of communication studies where a biological approach has been successfully applied. The book synthesizes theoretical and empirical development in this area thus far and proposes a roadmap for future research. As the biological approach to understanding communication has grown, one challenge has been the separate evolution of research focused on media use and effects and research focused on interpersonal and organizational communication, often with little intellectual conversation between the two areas. The Handbook of Communication Science and Biology is the only book to bridge the gap between media studies and human communication, spurring new work in both areas of focus. With contributions from the field’s foremost scholars around the globe, this unique book serves as a seminal resource for the training of the current and next generation of communication scientists, and will be of particular interest to media and psychology scholars as well.

Handbook of Statistical Bioinformatics

Author : Henry Horng-Shing Lu,Bernhard Schölkopf,Martin T. Wells,Hongyu Zhao
Publisher : Springer Nature
Page : 406 pages
File Size : 54,7 Mb
Release : 2022-12-08
Category : Science
ISBN : 9783662659021

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Handbook of Statistical Bioinformatics by Henry Horng-Shing Lu,Bernhard Schölkopf,Martin T. Wells,Hongyu Zhao Pdf

Now in its second edition, this handbook collects authoritative contributions on modern methods and tools in statistical bioinformatics with a focus on the interface between computational statistics and cutting-edge developments in computational biology. The three parts of the book cover statistical methods for single-cell analysis, network analysis, and systems biology, with contributions by leading experts addressing key topics in probabilistic and statistical modeling and the analysis of massive data sets generated by modern biotechnology. This handbook will serve as a useful reference source for students, researchers and practitioners in statistics, computer science and biological and biomedical research, who are interested in the latest developments in computational statistics as applied to computational biology.