Hepatitis And Liver Cancer

Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Prevention and Control of Viral Hepatitis Infections
Publisher : National Academies Press
Page : 252 pages
File Size : 47,7 Mb
Release : 2010-05-23
Category : Medical
ISBN : 9780309146289

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Hepatitis and Liver Cancer by Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Prevention and Control of Viral Hepatitis Infections Pdf

The global epidemic of hepatitis B and C is a serious public health problem. Hepatitis B and C are the major causes of chronic liver disease and liver cancer in the world. In the next 10 years, 150,000 people in the United States will die from liver disease or liver cancer associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. Today, between 800,000 and 1.4 million people in the United States have chronic hepatitis B and between 2.7 and 3.9 million have chronic hepatitis C. People most at risk for hepatitis B and C often are the least likely to have access to medical services. Reducing the rates of illness and death associated with these diseases will require greater awareness and knowledge among health care workers, improved identification of at-risk people, and improved access to medical care. Hepatitis B is a vaccine-preventable disease. Although federal public health officials recommend that all newborns, children, and at-risk adults receive the vaccine, about 46,000 new acute cases of the HBV infection emerge each year, including 1,000 in infants who acquire the infection during birth from their HBV-positive mothers. Unfortunately, there is no vaccine for hepatitis C, which is transmitted by direct exposure to infectious blood. Hepatitis and Liver Cancer identifies missed opportunities related to the prevention and control of HBV and HCV infections. The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis. It identifies priorities for research, policy, and action geared toward federal, state, and local public health officials, stakeholder, and advocacy groups and professional organizations.

Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Prevention and Control of Viral Hepatitis Infections
Publisher : National Academies Press
Page : 252 pages
File Size : 52,6 Mb
Release : 2010-04-23
Category : Medical
ISBN : 9780309153683

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Hepatitis and Liver Cancer by Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Prevention and Control of Viral Hepatitis Infections Pdf

The global epidemic of hepatitis B and C is a serious public health problem. Hepatitis B and C are the major causes of chronic liver disease and liver cancer in the world. In the next 10 years, 150,000 people in the United States will die from liver disease or liver cancer associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. Today, between 800,000 and 1.4 million people in the United States have chronic hepatitis B and between 2.7 and 3.9 million have chronic hepatitis C. People most at risk for hepatitis B and C often are the least likely to have access to medical services. Reducing the rates of illness and death associated with these diseases will require greater awareness and knowledge among health care workers, improved identification of at-risk people, and improved access to medical care. Hepatitis B is a vaccine-preventable disease. Although federal public health officials recommend that all newborns, children, and at-risk adults receive the vaccine, about 46,000 new acute cases of the HBV infection emerge each year, including 1,000 in infants who acquire the infection during birth from their HBV-positive mothers. Unfortunately, there is no vaccine for hepatitis C, which is transmitted by direct exposure to infectious blood. Hepatitis and Liver Cancer identifies missed opportunities related to the prevention and control of HBV and HCV infections. The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis. It identifies priorities for research, policy, and action geared toward federal, state, and local public health officials, stakeholder, and advocacy groups and professional organizations.

Author : Yujin Hoshida
Publisher : Springer
Page : 366 pages
File Size : 50,5 Mb
Release : 2019-08-05
Category : Medical
ISBN : 9783030215408

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Hepatocellular Carcinoma by Yujin Hoshida Pdf

This book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields. By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC.

Author : Ghassan K. Abou-Alfa
Publisher : Jones & Bartlett Publishers
Page : 166 pages
File Size : 55,9 Mb
Release : 2013
Category : Liver
ISBN : 9781449646875

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Dx/Rx by Ghassan K. Abou-Alfa Pdf

Author : Baruch S. Blumberg
Publisher : World Scientific
Page : 652 pages
File Size : 48,9 Mb
Release : 2000
Category : Medical
ISBN : 9810232179

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Hepatitis B and the Prevention of Primary Cancer of the Liver by Baruch S. Blumberg Pdf

This important book comprises a narrative account of research on the hepatitis B virus (and related subjects) and selected reprints from the laboratory of Nobel laureate Baruch S Blumberg and his colleagues. The hepatitis B virus (HBV) is one of the ten most common deadly infectious diseases and is responsible for 1.1 million deaths a year worldwide.Research in his laboratory resulted in the discovery of HBV and the invention of the vaccine which protects one against it. The research began as an apparently esoteric study of human biochemical and immunologic variation. This required field-work in Africa, the Arctic, the Pacific, the Americas, and in many other locations and populations. The overall goal was to identify inherited biological differences which were related to differing responses to disease-causing agents. The virus was discovered using the blood of an infected person who had developed the antibody, to detect the virus present in another infected person who had become a carrier of the virus. Screening of blood donors led to the near-elimination of post-transfusion hepatitis B.There are now national HBV vaccination programs in more than 70 countries. During the past decade these programs have strikingly reduced the prevalence of HBV in many countries and there has been a significant drop in the incidence of cancer of the liver in the vaccinated cohorts. The HBV vaccination program is now, after smoking cessation, the most widely used cancer prevention program in the world.

Author : Brian I. Carr
Publisher : Springer Nature
Page : 408 pages
File Size : 50,6 Mb
Release : 2021-09-22
Category : Medical
ISBN : 9783030787370

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Liver Cancer in the Middle East by Brian I. Carr Pdf

This book aims to illuminate the causes, incidence, and treatments of Hepatocellular Carcinoma(HCC) or liver cancer in the politically important and societally diverse region of the Middle East. Taking a flexible and inclusive view, it examines the influences of geography, crops and diet, ethnicity, and local behavior on both diagnosis and outcomes of this disease. Understanding the different causes of liver cancer enables effective strategies for both prevention and early diagnosis while knowledge of the different treatment modalities, their uses and limitations, availability and costs, works to inform rational treatment provision and selection. Divided into four sections, this book considers the causes and clinical syndromes associated with HCC, provides a detailed overview of clinical HCC and treatment modalities, describes country-specific clinical HCC experience and practice, and considers future needs and the potential for HCC collaborations across the region. Liver Cancer in the Middle East is a useful resource for clinicians seeking insight into the second highest cause of death from cancer worldwide, governments planning social and medical services for their peoples, as well as for international aid agencies prioritizing donations.

Author : Ghassan K. Abou-Alfa,Celina Ang
Publisher : Jones & Bartlett Publishers
Page : 167 pages
File Size : 46,8 Mb
Release : 2012-12-23
Category : Medical
ISBN : 9781449686178

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Dx/Rx: Liver Cancer by Ghassan K. Abou-Alfa,Celina Ang Pdf

Dx/Rx: Liver Cancer is a quick and practical reference guide containing all aspects of the diagnosis and therapy of hepatocellular carcinoma (HCC), prognostic and staging systems, clinical management, molecular biology, current controversies, and future insights. Organized into a condensed, bulleted format, this concise reference offers precise and up-to-date information on the epidemiology, classification, diagnosis, treatment, and risk factors for cancers of the liver. Presented in a handy, easy-to-read format, Dx/Rx: Liver Cancer is a must-have resource for oncologists, internists, primary care physicians, and other health care professionals on the ward or in the clinic.

Author : World Health Organization
Publisher : World Health Organization
Page : 0 pages
File Size : 55,6 Mb
Release : 2017
Category : Medical
ISBN : 924154998X

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Guidelines on Hepatitis B and C Testing by World Health Organization Pdf

Testing and diagnosis of hepatitis B (HBV) and C (HCV) infection is the gateway for access to both prevention and treatment services, and is a crucial component of an effective response to the hepatitis epidemic. Early identification of persons with chronic HBV or HCV infection enables them to receive the necessary care and treatment to prevent or delay progression of liver disease. Testing also provides an opportunity to link people to interventions to reduce transmission, through counselling on risk behaviors and provision of prevention commodities (such as sterile needles and syringes) and hepatitis B vaccination. These are the first WHO guidelines on testing for chronic HBV and HCV infection and complement published guidance by WHO on the prevention, care and treatment of chronic hepatitis C and hepatitis B infection. These guidelines outline the public health approach to strengthening and expanding current testing practices for HBV and HCV, and are intended for use across age groups and populations.

Author : Ganji Purnachandra Nagaraju,Sujatha Peela
Publisher : Academic Press
Page : 388 pages
File Size : 48,8 Mb
Release : 2022-02-16
Category : Psychology
ISBN : 9780323993647

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Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 1 by Ganji Purnachandra Nagaraju,Sujatha Peela Pdf

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume One: Biology and Pathophysiology provides comprehensive information about ongoing research and clinical data surrounding liver cancer. The book presents detailed descriptions about diagnostics and therapeutic options for easy understanding, with a focus on precision medicine approaches to improve treatment outcomes. This volume discusses topics such as tumor microenvironment in hepatocellular carcinoma, endoplasmic reticulum stress and unfolded protein response, effects of cirrhosis and hepatitis on the prognosis of HCC, mitochondrial metabolism, next generation sequencing, and telomerase. In addition, it discusses exosomes role in HCC progression, metastasis and chemokines. This is a valuable resource for cancer researchers, oncologists, graduate students, hepathologists and members of biomedical research who need to understand more about liver cancer for their research work or clinical setting. Provides an updated literature review and detailed understanding of liver cancer tumor biology Discusses abnormal changes in the liver caused, resulting from, or associated with hepatocellular carcinoma from a holistic view Presents the content with fully colored images and summarizing tables for easy understanding of complex topics

Author : Hesham Abdeldayem
Publisher : BoD – Books on Demand
Page : 224 pages
File Size : 53,8 Mb
Release : 2017-04-05
Category : Medical
ISBN : 9789535130635

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Updates in Liver Cancer by Hesham Abdeldayem Pdf

Liver cancers result in considerable amount of financial and social burden. On the other hand, researches and clinical studies related to liver cancers continue to advance at a rapid pace. The chapters in this book provide state-of-the-art reviews on the current knowledge and advances in research and management of liver cancers. It includes the most recent advances in that field, particularly, hepatocarcinogenesis and the potential role of intestinal microbiota, nonalcoholic steatohepatitis, cancer stem cells, aldehyde dehydrogenase-1, and hepatitis B virus. This book also discusses the methods of diagnosis of HCC, the minimally invasive therapies for liver cancers, living donor liver transplantation for HCC, surgical management of liver metastases from colorectal cancers, and assessment and optimization for the future liver remnant.

Author : E. Tabor
Publisher : Gulf Professional Publishing
Page : 192 pages
File Size : 51,5 Mb
Release : 2002-06-18
Category : Medical
ISBN : 0444505806

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Viruses and Liver Cancer by E. Tabor Pdf

Hepatocellular carcinoma (HCC) is one of the most common human cancers. Its association with chronic hepatitis B and C virus infections is well established. As one of the first human cancers to be etiologically associated with any virus, it provides a model for studying viral carcinogenesis in humans. The latest concepts in molecular biology have been brought to bear on the study of HCC and have led to dramatic breakthroughs in our understanding of how it develops.

Author : Brian I. Carr
Publisher : Springer
Page : 50 pages
File Size : 44,7 Mb
Release : 2014-07-17
Category : Medical
ISBN : 9781910315026

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Understanding Liver Cancer by Brian I. Carr Pdf

​Understanding Liver Cancer is a concise and up-to-date review, which discusses diagnosis, management, patient care, current and emerging therapies, and useful resources that clinicians can provide to their patients. Busy healthcare professionals who want a quick review of liver cancer as well as a summary of current therapies will benefit from this succinct text.

Author : Michio Mori,Michihiro C. Yoshida,Noritoshi Takeichi,Naoyuki Taniguchi
Publisher : Springer Science & Business Media
Page : 365 pages
File Size : 54,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9784431681533

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The LEC Rat by Michio Mori,Michihiro C. Yoshida,Noritoshi Takeichi,Naoyuki Taniguchi Pdf

The LEC strain of rats, which spontaneously develop acute hepatitis as sociated with jaundice, chronic hepatitis, and ultimately hepatocellular carcinomas, was established by scientists in Sapporo, Japan. Careful ob servation and breeding led to the initial discovery of this characteristic, inherited liver disease in rats. Subsequent collaboration between scientists in Sapporo and other centers has revealed an autosomal recessive nature of inheritance, along with a variety of histopathological and biochemical findings. The causative mechanism(s) underlying this abnormality remained a mystery for some time, providing a challenge for many scientists who were attracted to the quest for clues to this enigma. In particular, the mech anism of spontaneous development of hepatocellular carcinomas in rats overcoming the acute phase of hepatitis and surviving with chronic hepatitis proved extremely interesting, because the involvement of a causative virus had been excluded in the early stages of investigation. Professor Michio Mori of Sapporo Medical College played a key role in the study of LEC rats, especially in the elucidation of the pathogenesis of hepatitis and hepatocellular carcinoma. He is one of the editors of this monograph which is composed of original contributions by the many scientists who have carried out their own studies on LEC rats. Of the various histopathological and biochemical alterations which have been reported, some are clearly secondary or tertiary events sequential to the primary change caused by gene mutation.

Author : Ghassan K. Abou-Alfa,Ronald DeMatteo
Publisher : Jones & Bartlett Publishers
Page : 207 pages
File Size : 41,8 Mb
Release : 2008-12-24
Category : Medical
ISBN : 9780763787462

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100 Questions and Answers about Liver Cancer by Ghassan K. Abou-Alfa,Ronald DeMatteo Pdf

EMPOWER YOURSELF! Whether you're a newly diagnosed liver cancer patient, a survivor, or a friend or relative of either, this book offers help. The only text to provide the doctor's and patient's views, 100 Questions & Answers About Liver Cancer, Second Edition gives you authoritative, practical answers to your questions about treatment options, post-treatment quality of life, sources of support, and much more. Written by a medical oncologist and a gastrointestinal surgeon, with actual patient commentary, this book is an invaluable resource for anyone coping with the physical and emotional turmoil of this frightening disease.

Author : Adrian Reuben
Publisher : Elsevier Health Sciences
Page : 268 pages
File Size : 49,9 Mb
Release : 2011-05-28
Category : Medical
ISBN : 9781455712373

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Hepatocellular Carcinoma, An Issue of Clinics in Liver Disease by Adrian Reuben Pdf

Dr. Adrian Reuben updates one of the most highly requested topics in liver disease by inviting highly distinguished authors to address the important aspects of diagnosis and treatment of hepatocelluar carcinoma. State-of-the-art issues are addressed, including the role of oncogenic viruses, molecular and genetic guidelines, and screening and staging. Dr. Reuben, himself, concludes the issue with an important article on an agorithmic approach to diagnosis and treatment: Resect, Ablate, Replace or Intoxicate?