Hepatitis C

Author : Resat Ozaras,Dominique Salmon-Ceron
Publisher : Springer
Page : 0 pages
File Size : 40,6 Mb
Release : 2019-07-06
Category : Medical
ISBN : 3030037568

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Viral Hepatitis: Chronic Hepatitis C by Resat Ozaras,Dominique Salmon-Ceron Pdf

This book presents up-to-date, practically oriented information on major topics in chronic hepatitis C. The coverage encompasses epidemiology; diagnosis, including molecular methods; treatment and challenges; and the management of co-infections. Readers will find guidance on pretherapeutic evaluation with respect to disease severity and extrahepatic manifestations. Resistance to antiviral treatment and its management are discussed, and the nature of optimal follow-up is addressed in detail. Treatment of HCV/HIV co-infection is considered separately, and the approach in special patient populations is thoroughly examined. Chronic Hepatitis C will be of high value for general practitioners and specialists in gastroenterology, infectious diseases, and internal medicine. It will be international in scope in terms of both authorship and appeal.

Author : Ralf Bartenschlager
Publisher : Springer Science & Business Media
Page : 353 pages
File Size : 42,6 Mb
Release : 2013-03-12
Category : Medical
ISBN : 9783642273407

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Hepatitis C Virus: From Molecular Virology to Antiviral Therapy by Ralf Bartenschlager Pdf

Hepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected. In this volume, world-leading experts in the field of HCV research have compiled the most recent scientific advances to provide a comprehensive and very timely overview of the various facets of HCV. The book starts with a discussion of the possible origin of HCV and its spread among the human population. The focus of the subsequent chapters is on available cell culture and in vivo models before shifting to the molecular and cellular principles underlying the viral replication cycle. These chapters are complemented by insightful descriptions of the innate and adaptive immune responses to HCV as well as the virus-associated pathogenesis. Finally, the development of antiviral therapies, which is closely linked with progress in basic research, and the implementation of those therapies into present and future daily clinical practice are highlighted.

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on a National Strategy for the Elimination of Hepatitis B and C
Publisher : National Academies Press
Page : 187 pages
File Size : 43,5 Mb
Release : 2016-06-01
Category : Medical
ISBN : 9780309438025

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Eliminating the Public Health Problem of Hepatitis B and C in the United States by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on a National Strategy for the Elimination of Hepatitis B and C Pdf

Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the first of two, examines the feasibility of hepatitis B and C elimination in the United States and identifies critical success factors. The phase two report will outline a strategy for meeting the elimination goals discussed in this report.

Author : World Health Organization
Publisher : World Health Organization
Page : 0 pages
File Size : 41,5 Mb
Release : 2017
Category : Medical
ISBN : 924154998X

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Guidelines on Hepatitis B and C Testing by World Health Organization Pdf

Testing and diagnosis of hepatitis B (HBV) and C (HCV) infection is the gateway for access to both prevention and treatment services, and is a crucial component of an effective response to the hepatitis epidemic. Early identification of persons with chronic HBV or HCV infection enables them to receive the necessary care and treatment to prevent or delay progression of liver disease. Testing also provides an opportunity to link people to interventions to reduce transmission, through counselling on risk behaviors and provision of prevention commodities (such as sterile needles and syringes) and hepatitis B vaccination. These are the first WHO guidelines on testing for chronic HBV and HCV infection and complement published guidance by WHO on the prevention, care and treatment of chronic hepatitis C and hepatitis B infection. These guidelines outline the public health approach to strengthening and expanding current testing practices for HBV and HCV, and are intended for use across age groups and populations.

Author : Tatsuo Miyamura,Stanley M. Lemon,Christopher M. Walker,Takaji Wakita
Publisher : Springer
Page : 0 pages
File Size : 46,5 Mb
Release : 2016-11-08
Category : Medical
ISBN : 4431560963

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Hepatitis C Virus I by Tatsuo Miyamura,Stanley M. Lemon,Christopher M. Walker,Takaji Wakita Pdf

This volume is composed of chapters that review important fundamental aspects of HCV biology and disease pathogenesis including, for example, the discovery and identification of the HCV genome, early virus-cell interactions including identification of various cellular receptors, HCV gene expression studied using the HCV replicon system, identification and characterization of HCV structural- and non-structural HCV proteins, HCV replication in cultured cells, and host factors involved in viral replication. This volume also contains chapters dealing with immunity to HCV infection and pathogenesis. This is particularly important in understanding hepatitis C because HCV infection alone is not cell lytic. Mechanisms underlying the persistent nature of HCV infection are also discussed in these chapters. Many of the authors published articles that were listed among the “top 10 papers” published in the 24 years since HCV was discovered in 1989. Their citations are above 1,000 (Web of Science). The authors describe the background and significance of their contributions to the field in the context of findings from other research groups.

Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Prevention and Control of Viral Hepatitis Infections
Publisher : National Academies Press
Page : 252 pages
File Size : 44,7 Mb
Release : 2010-05-23
Category : Medical
ISBN : 9780309146289

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Hepatitis and Liver Cancer by Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Prevention and Control of Viral Hepatitis Infections Pdf

The global epidemic of hepatitis B and C is a serious public health problem. Hepatitis B and C are the major causes of chronic liver disease and liver cancer in the world. In the next 10 years, 150,000 people in the United States will die from liver disease or liver cancer associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. Today, between 800,000 and 1.4 million people in the United States have chronic hepatitis B and between 2.7 and 3.9 million have chronic hepatitis C. People most at risk for hepatitis B and C often are the least likely to have access to medical services. Reducing the rates of illness and death associated with these diseases will require greater awareness and knowledge among health care workers, improved identification of at-risk people, and improved access to medical care. Hepatitis B is a vaccine-preventable disease. Although federal public health officials recommend that all newborns, children, and at-risk adults receive the vaccine, about 46,000 new acute cases of the HBV infection emerge each year, including 1,000 in infants who acquire the infection during birth from their HBV-positive mothers. Unfortunately, there is no vaccine for hepatitis C, which is transmitted by direct exposure to infectious blood. Hepatitis and Liver Cancer identifies missed opportunities related to the prevention and control of HBV and HCV infections. The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis. It identifies priorities for research, policy, and action geared toward federal, state, and local public health officials, stakeholder, and advocacy groups and professional organizations.

Author : Martina Smolic,Aleksandar Vcev,George Wu
Publisher : BoD – Books on Demand
Page : 240 pages
File Size : 48,9 Mb
Release : 2017-10-04
Category : Medical
ISBN : 9789535135630

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Update on Hepatitis C by Martina Smolic,Aleksandar Vcev,George Wu Pdf

In the past few years, remarkable progress has been made in our understanding of HCV biology, pathogenesis of infection, and structure-function relationships. This has led to quantum advances in clinical efficacy and tolerability. Yet, in spite of this amazing progress, there remain obstacles to widespread successful treatment. These issues include biological failures even with direct-acting agents, lack of options for individual with organ failures, drug-drug interactions, access to medications either due to lack of availability or affordability, and psychiatric and social issues. These problems are likely to remain in the future. Therefore, this book has been created by distinguished faculties from around the world to address the progress in our understanding of HCV infection and to review new treatment options, limitations, and accessibility of new therapeutic options.

Author : Gregory T. Everson
Publisher : Hatherleigh Press
Page : 272 pages
File Size : 48,7 Mb
Release : 2009-09-29
Category : Health & Fitness
ISBN : 9781578263509

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Living with Hepatitis C, Fifth Edition by Gregory T. Everson Pdf

The Most Trusted Resource and Reference for Millions of Americans Living with Hepatitis C was the first book to explain in everyday language the causes of this disease, its major and minor symptoms, and all of the latest treatments available. Researchers have continued to make dramatic strides in helping the millions of Americans who suffer from Hepatitis C since the book's first publication, and each new edition has kept up with the most recent findings. The latest revised Living With Hepatitis C, Fifth Edition includes cutting-edge information on: * New treatments including pegylated and consensus interferons * Living-donor transplants * Co-infections with Hepatitis B and HIV/AIDS * Promising new clinical trials of protease and polymerase inhibitors * New maintenance therapies, an expanded and updated resource section, ways to avoid infection, and much more Living with Hepatitis C, Fifth Edition is still the "gold standard" resource and reference for those who must endure this disease. It offers guidance and answers for those infected by the virus--and for their spouses, families, and friends.

Author : Gregory T. Everson
Publisher : Hatherleigh Press
Page : 185 pages
File Size : 49,7 Mb
Release : 2012-08-21
Category : Health & Fitness
ISBN : 9781578264407

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Curing Hepatitis C by Gregory T. Everson Pdf

Hepatitis C Doesn't Have to Be a Lifelong Illness Curing Hepatitis C provides the latest information to guide you through the diagnosis and treatment of hepatitis C. If you or a loved one has been diagnosed with hepatitis C, this book provides an indispensable and comprehensive overview of everything you need to know to take the right steps toward a cure. For the nearly 160 million people worldwide and 4 million Americans diagnosed with hepatitis C, there is now hope. Although hepatitis C was once considered incurable, medical and technological innovations have made a cure possible. A new frontier of treatment options has improved upon previous methods by curbing side-effects more effectively and working to eradicate hepatitis C entirely. Curing Hepatitis C also includes: * Easy-to-understand explanations of the nature of hepatitis C * The revealing truth of misconceptions about hepatitis C * Tips to prevent, diagnose, cope with, and ultimately cure this disease * An overview of types of tests and how to understand your results * Breakthrough treatments and medications for hepatitis C, such as triple therapy * The next generation of treatments including interferon-free regimens, QUAD therapy, host-acting antivirals, and more * Personal anecdotes from those affected by hepatitis C

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on a National Strategy for the Elimination of Hepatitis B and C
Publisher : National Academies Press
Page : 297 pages
File Size : 54,7 Mb
Release : 2017-06-30
Category : Medical
ISBN : 9780309457323

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A National Strategy for the Elimination of Hepatitis B and C by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on a National Strategy for the Elimination of Hepatitis B and C Pdf

Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the second of two, builds off the conclusions of the first report and outlines a strategy for hepatitis reduction over time and specific actions to achieve them.

Author : Matthew Dolan
Publisher : Unknown
Page : 473 pages
File Size : 50,5 Mb
Release : 1999
Category : Health & Fitness
ISBN : 1556433131

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The Hepatitis C Handbook by Matthew Dolan Pdf

This definitive guide explains the symptoms and treatments of Hepatitis C and how to cope with the disease and features extensive sections on herbs, vitamins, and nutritional supplements.

Author : Paul Arguin
Publisher : Unknown
Page : 128 pages
File Size : 55,8 Mb
Release : 2005
Category : Electronic
ISBN : OCLC:729272633

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Health Information for International Travel 2005-2006 by Paul Arguin Pdf

Author : Beth Ann Petro Roybal
Publisher : Simon and Schuster
Page : 186 pages
File Size : 47,9 Mb
Release : 2002-09-05
Category : Health & Fitness
ISBN : 9781569751343

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Hepatitis C by Beth Ann Petro Roybal Pdf

A Simon & Schuster eBook. Simon & Schuster has a great book for every reader.

Author : Fred Askari
Publisher : Da Capo Press
Page : 242 pages
File Size : 48,9 Mb
Release : 2007-10-09
Category : Health & Fitness
ISBN : 9780738211978

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Hepatitis C by Fred Askari Pdf

Four million Americans have been stricken by Hepatitis C, and the numbers continue to grow. Covering every aspect of this serious liver disease, Dr. Fred Askari provides a clear and compassionate description of the complex medical issues that many doctors fail to adequately explain to their patients. Complete with a targeted resource list of support groups and organizations, Hepatitis C: The Silent Epidemic delivers the facts on the symptoms as well as up-to-the-minute news on drug and transplant treatment options.

Author : World Health Organization
Publisher : Unknown
Page : 114 pages
File Size : 46,7 Mb
Release : 2016-06-24
Category : Medical
ISBN : 924154855X

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Blood Donor Counselling by World Health Organization Pdf

Individuals who donate their blood provide a unique and precious gift in an act of human solidarity. In order to donate blood, prospective donors should be in good health and free from any infections that can be transmitted through transfusion. Most blood donors perceive themselves to be healthy, but some are unsuitable to donate blood due to the potential risk of compromising or worsening their own health or the risk of transmission of infections to patients. Blood transfusion services (BTS) have a duty of care towards blood donors as well as to the recipients of transfusion. This duty of care extends to prospective donors who are deferred from donation--whether on a temporary or permanent basis--as well as those who donate blood and are subsequently found to have unusual or abnormal test results. BTS have a responsibility to confirm test results and provide information, counseling and support to enable these individuals to understand and respond to unexpected information about their health or risk status. Counseling is part of the spectrum of care that a BTS should be able to provide to blood donors--including referral to medical practitioners or specialist clinical services. Pre-donation counseling was recognized as one element of the strategy to reduce and, if possible, prevent the donation of blood by individuals who might be at risk for HIV and other TTI including hepatitis B and C viruses as well as to inform the donor of the donation process and testing of blood for HIV. Post-donation counseling was acknowledged to be a necessary element of donor management as an adjunct to informing donors of unusual or abnormal test results. Blood donor counseling by trained specialist staff is now considered to be a key component of the blood system in most countries with a well-developed blood transfusion service. It may be required at a number of stages in the blood donation process or following blood screening and should be available at any point at which the BTS has an interface with donors. In many countries, however, blood donor counseling is not yet available in a structured way. Blood Donor Counselling: Implementation Guidelines has therefore been developed to provide guidance to blood transfusion services that have not yet established donor counseling programs.