High Containment Laboratories

Author : Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories,Board on Life Sciences,Committee on International Security and Arms Control,Division on Earth and Life Studies,Policy and Global Affairs,National Academy of Sciences,National Research Council
Publisher : National Academies Press
Page : 216 pages
File Size : 53,7 Mb
Release : 2012-03-16
Category : Political Science
ISBN : 9780309225762

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Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories by Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories,Board on Life Sciences,Committee on International Security and Arms Control,Division on Earth and Life Studies,Policy and Global Affairs,National Academy of Sciences,National Research Council Pdf

During July 10-13, 2011, 68 participants from 32 countries gathered in Istanbul, Turkey for a workshop organized by the United States National Research Council on Anticipating Biosecurity Challenges of the Global Expansion of High-containment Biological Laboratories. The United States Department of State's Biosecurity Engagement Program sponsored the workshop, which was held in partnership with the Turkish Academy of Sciences. The international workshop examined biosafety and biosecurity issues related to the design, construction, maintenance, and operation of high-containment biological laboratories- equivalent to United States Centers for Disease Control and Prevention biological safety level 3 or 4 labs. Although these laboratories are needed to characterize highly dangerous human and animal pathogens, assist in disease surveillance, and produce vaccines, they are complex systems with inherent risks. Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories summarizes the workshop discussion, which included the following topics: Technological options to meet diagnostic, research, and other goals; Laboratory construction and commissioning; Operational maintenance to provide sustainable capabilities, safety, and security; and Measures for encouraging a culture of responsible conduct. Workshop attendees described the history and current challenges they face in their individual laboratories. Speakers recounted steps they were taking to improve safety and security, from running training programs to implementing a variety of personnel reliability measures. Many also spoke about physical security, access controls, and monitoring pathogen inventories. Workshop participants also identified tensions in the field and suggested possible areas for action.

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs
Publisher : National Academies Press
Page : 121 pages
File Size : 42,9 Mb
Release : 2019-05-01
Category : Science
ISBN : 9780309486569

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Developing Norms for the Provision of Biological Laboratories in Low-Resource Contexts by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs Pdf

On June 27-28, 2018, the U.S. National Academies of Sciences, Engineering, and Medicine (the National Academies) convened an international workshop in Amsterdam, the Netherlands, on developing norms for the provision of laboratories in low-resource contexts. The U.S. Department of State's Biosecurity Engagement Program requested that the National Academies organize this workshop to engage an international group of organizations that provide funding for construction, upgrades, and maintenance of biological laboratories in countries without the means to build such labs themselves. Twenty-one people from 19 organizations participated. The intent was to advance the conversation about the identification and application of guiding principles and common norms for use by these organizations in their grants, partnerships, and aid. This publication summarizes the presentations and discussions from the workshop.

Author : Ann Wright
Publisher : DIANE Publishing
Page : 104 pages
File Size : 55,6 Mb
Release : 2010
Category : Science
ISBN : 9781437922721

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High-Containment Laboratories by Ann Wright Pdf

U.S. laboratories working with dangerous biological pathogens (commonly referred to as high-containment laboratories) have proliferated in recent years. As a result, the public is concerned about the oversight of these laboratories. The deliberate or accidental release of biological pathogens can have disastrous consequences. This report determines: (1) to what extent, and in what areas, the number of high-containment laboratories has increased in the U.S.; (2) which federal agency is responsible for tracking this expansion and determining the associated aggregate risks; and (3) lessons learned from highly publicized incidents at these laboratories and actions taken by the regulatory agencies. Charts and tables.

Author : National Research Council,National Academy of Sciences,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs,Committee on International Security and Arms Control,Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories
Publisher : National Academies Press
Page : 216 pages
File Size : 40,8 Mb
Release : 2012-04-02
Category : Political Science
ISBN : 9780309225755

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Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories by National Research Council,National Academy of Sciences,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs,Committee on International Security and Arms Control,Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories Pdf

During July 10-13, 2011, 68 participants from 32 countries gathered in Istanbul, Turkey for a workshop organized by the United States National Research Council on Anticipating Biosecurity Challenges of the Global Expansion of High-containment Biological Laboratories. The United States Department of State's Biosecurity Engagement Program sponsored the workshop, which was held in partnership with the Turkish Academy of Sciences. The international workshop examined biosafety and biosecurity issues related to the design, construction, maintenance, and operation of high-containment biological laboratories- equivalent to United States Centers for Disease Control and Prevention biological safety level 3 or 4 labs. Although these laboratories are needed to characterize highly dangerous human and animal pathogens, assist in disease surveillance, and produce vaccines, they are complex systems with inherent risks. Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories summarizes the workshop discussion, which included the following topics: Technological options to meet diagnostic, research, and other goals; Laboratory construction and commissioning; Operational maintenance to provide sustainable capabilities, safety, and security; and Measures for encouraging a culture of responsible conduct. Workshop attendees described the history and current challenges they face in their individual laboratories. Speakers recounted steps they were taking to improve safety and security, from running training programs to implementing a variety of personnel reliability measures. Many also spoke about physical security, access controls, and monitoring pathogen inventories. Workshop participants also identified tensions in the field and suggested possible areas for action.

Author : Frank Gottron
Publisher : DIANE Publishing
Page : 33 pages
File Size : 40,6 Mb
Release : 2009-12
Category : Science
ISBN : 9781437919370

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Oversight of High-Containment Biological Laboratories by Frank Gottron Pdf

The fed. gov¿t. responded to the 9/11 terrorist attacks and the subsequent anthrax attacks with increased focus on and funding for biodefense. High-containment labs. (HCL) play a critical role in the biodefense effort, offering the hope of better responses to an attack and a better understanding of the threat posed by bioterrorism. However, they also could increase the risk of a biological attack by serving as a potential source of materials or training. Policymakers have become increasingly interested in the oversight of these facilities following reports of accidents, regulatory noncompliance, and community resistance. A key task for policymakers is to define their goals for enhancing oversight of HCL. Illustrations

Author : Marcia Crosse,John Neumann
Publisher : Unknown
Page : 92 pages
File Size : 41,9 Mb
Release : 2016-05-22
Category : Electronic
ISBN : 1457873230

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High-Containment Laboratories by Marcia Crosse,John Neumann Pdf

Safety lapses at federal high-containment laboratories in 2014 and 2015 raised concerns about federal departments' oversight of these laboratories. Such laboratories work with hazardous biological agents to develop measures to protect public and animal health and the food supply against these agents. This report examines (1) the extent to which federal agencies have comprehensive and up-to-date policies for managing biological agents in these laboratories; (2) how they oversee laboratories; and (3) the extent to which the Departments of Health and Human Services (HHS) and Defense (DOD) have implemented recommendations from laboratory safety reviews. Tables. This is a print on demand report.

Author : U.s. Government Accountability Office
Publisher : Createspace Independent Publishing Platform
Page : 92 pages
File Size : 43,8 Mb
Release : 2017-07-25
Category : Electronic
ISBN : 1973911205

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High-containment Laboratories, Comprehensive and Up-to-date Policies and Stronger Oversight Mechanisms Needed to Improve Safety by U.s. Government Accountability Office Pdf

" Safety lapses at federal high-containment laboratories in 2014 and 2015 raised concerns about federal departments' oversight of these laboratories. These laboratories work with hazardous biological agents to develop measures to protect public and animal health and the food supply against these agents. GAO was asked to review oversight at federal high-containment laboratories. This report examines (1) the extent to which federal agencies have comprehensive and up-to-date policies for managing biological agents in these laboratories, (2) how they oversee laboratories, and (3) the extent to which HHS and DOD have implemented recommendations from laboratory safety reviews. GAO assessed policies and oversight activities at 8 departments and their 15 component agencies that own and operate high-containment laboratories against federal internal control standards and program management leading practices, reviewed plans for implementing laboratory safety recommendations, and interviewed federal officials. "

Author : Great Britain. Parliament. House of Commons. Innovation, Universities, Science and Skills Committee
Publisher : The Stationery Office
Page : 68 pages
File Size : 46,7 Mb
Release : 2008
Category : Science
ISBN : 0215521242

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Biosecurity in UK Research Laboratories by Great Britain. Parliament. House of Commons. Innovation, Universities, Science and Skills Committee Pdf

Possessing the high containment laboratories necessary to tackle existing and emergent infectious diseases of both humans and animals is of the utmost importance to the UK. A leak of Foot and Mouth disease from such a laboratory at Pirbright in 2007 is the most recent demonstration of how devastating infectious disease can be. It is critical that such an incident does not happen again. This Report outlines a number of shortcomings in the way capacity for high containment research is provided and highlights where the Government should take action. Primarily, the Committee concludes that there is a striking lack of co-ordination between organisations who sponsor and run high containment laboratories. No one organisation or Minister has the remit to maintain a strategic overview of capacity and to co-ordinate these laboratories. There is significant potential for collaboration at a more formal level to assess what facilities are available and make best use of them, identifying any gaps. There is also room for more co-ordination and standardisation of the vetting and training of staff working in this area. The report identifies shortcomings in the funding of high containment facilities, particularly for the significant cost of ongoing maintenance. A number of high containment laboratories have been neglected and the funding situation is uncertain. The Government must ensure that dependable funding is provided to maintain such facilities safely. The new regulatory framework to be introduced in the wake of the Pirbright outbreak is a positive step and should provide a framework in which those operating high containment facilities, given sufficient resources, should be able to continue their work to protect the UK from the threat of infectious disease.

Author : United States Government Accountability Office
Publisher : Createspace Independent Publishing Platform
Page : 28 pages
File Size : 54,9 Mb
Release : 2018-05-11
Category : Electronic
ISBN : 1718974981

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High-Containment Laboratories by United States Government Accountability Office Pdf

HIGH-CONTAINMENT LABORATORIES: Recent Incidents of Biosafety Lapses

Author : Nancy Kingsbury
Publisher : DIANE Publishing
Page : 33 pages
File Size : 50,7 Mb
Release : 2009
Category : Health & Fitness
ISBN : 9781437905953

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High-Containment Biosafety Laboratories by Nancy Kingsbury Pdf

The Dept. of Homeland Security (DHS) is proposing to move foot-and-mouth disease (FMD) research from its current location on a federally owned island off the northern tip of Long Island, NY -- and potentially into the U.S. mainland. FMD is the most highly infectious animal disease that is known. A single outbreak of FMD on the U.S. mainland could have significant economic consequences. This report evaluates the evidence DHS used to support its decision that FMD work can be done safely on the U.S. mainland, whether an island location provides any additional protection over and above that provided by modern high containment labs. on the mainland, and the economic consequences of an FMD outbreak on the U.S. mainland. Illus.

Author : Damon S. Samuels
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 51,8 Mb
Release : 2010
Category : Biological laboratories
ISBN : 1616687061

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Biosafety and Biosecurity Issues in High-Containment Laboratories by Damon S. Samuels Pdf

Stringent protocols and engineering are used to contain the most dangerous pathogens, therefore these facilities are often referred to as high-containment laboratories. High-containment laboratories play a critical role in the biodefense effort, offering the hope of better responses to a biological attack and a better understanding of the bioterrorism threat. However, they could also increase the risk of a biological attack by being a source of materials or training. This book examines the biosafety and biosecurity issues in high-containment laboratories across the United States.

Author : Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on Hazardous Biological Substances in the Laboratory,National Research Council
Publisher : National Academies Press
Page : 237 pages
File Size : 49,8 Mb
Release : 1989-01-01
Category : Science
ISBN : 9780309039758

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Biosafety in the Laboratory by Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on Hazardous Biological Substances in the Laboratory,National Research Council Pdf

Biosafety in the Laboratory is a concise set of practical guidelines for handling and disposing of biohazardous material. The consensus of top experts in laboratory safety, this volume provides the information needed for immediate improvement of safety practices. It discusses high- and low-risk biological agents (including the highest-risk materials handled in labs today), presents the "seven basic rules of biosafety," addresses special issues such as the shipping of dangerous materials, covers waste disposal in detail, offers a checklist for administering laboratory safetyâ€"and more.

Author : United States. Government Accountability Office
Publisher : Unknown
Page : 128 pages
File Size : 48,8 Mb
Release : 2009
Category : Electronic
ISBN : OCLC:1231259971

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High-containment Laboratories :. by United States. Government Accountability Office Pdf

Author : Damon S. Samuels
Publisher : Unknown
Page : 128 pages
File Size : 43,6 Mb
Release : 2010
Category : Political Science
ISBN : 1616687924

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Biosafety and Biosecurity Issues in High-containment Laboratories by Damon S. Samuels Pdf

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee to Review the Health and Safety Risks of High-Biocontainment Laboratories at Fort Detrick
Publisher : National Academies Press
Page : 86 pages
File Size : 51,8 Mb
Release : 2010-06-12
Category : Political Science
ISBN : 9780309151450

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Evaluation of the Health and Safety Risks of the New USAMRIID High-Containment Facilities at Fort Detrick, Maryland by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee to Review the Health and Safety Risks of High-Biocontainment Laboratories at Fort Detrick Pdf

The U.S. Army Medical Research Institute of Infectious Diseases in Frederick, Maryland, is designed to handle pathogens that cause serious or potentially lethal diseases, which require the research performed on them be contained to specialized laboratories. In 2007 a decision was made to expand those facilities causing concern among area residents that public health and safety risks, and strategies to mitigate those concerns were not adequately considered in the decision to go forward with the expansion. In Evaluation of the Health and Safety Risks of the New USAMRIID High Containment Facilities at Fort Detrick, Maryland a group of experts in areas including biosafety, infectious diseases, industrial hygiene, environmental engineering, risk assessment and epidemiology, explored whether measures were being taken to ensure prevention and mitigation of risk to the health and safety of workers and the public. They also assessed whether the procedures and regulations employed meet accepted standards of the Centers for Disease Control and Prevention and the National Institutes of Health. Evaluation of the Health and Safety Risks of the New USAMRIID High Containment Facilities at Fort Detrick, Maryland evaluates the health and safety aspects of the environmental impact statement developed to support the construction of the new laboratories and explores the institute's operating requirements, medical and emergency management response plans and communication and cooperation with the public. The book recommends that USAMRIID continue to set high standards for advancing security, operational, and biosurety measures, and that additional measures be taken to provide assurance that experienced medical professionals are readily available to consult on unusual infectious diseases. It also suggests that USAMRIID expand its two-way communications with the public.