Biosecurity In Uk Research Laboratories

Author : Great Britain. Parliament. House of Commons. Innovation, Universities, Science and Skills Committee
Publisher : The Stationery Office
Page : 68 pages
File Size : 52,7 Mb
Release : 2008
Category : Science
ISBN : 0215521242

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Biosecurity in UK Research Laboratories by Great Britain. Parliament. House of Commons. Innovation, Universities, Science and Skills Committee Pdf

Possessing the high containment laboratories necessary to tackle existing and emergent infectious diseases of both humans and animals is of the utmost importance to the UK. A leak of Foot and Mouth disease from such a laboratory at Pirbright in 2007 is the most recent demonstration of how devastating infectious disease can be. It is critical that such an incident does not happen again. This Report outlines a number of shortcomings in the way capacity for high containment research is provided and highlights where the Government should take action. Primarily, the Committee concludes that there is a striking lack of co-ordination between organisations who sponsor and run high containment laboratories. No one organisation or Minister has the remit to maintain a strategic overview of capacity and to co-ordinate these laboratories. There is significant potential for collaboration at a more formal level to assess what facilities are available and make best use of them, identifying any gaps. There is also room for more co-ordination and standardisation of the vetting and training of staff working in this area. The report identifies shortcomings in the funding of high containment facilities, particularly for the significant cost of ongoing maintenance. A number of high containment laboratories have been neglected and the funding situation is uncertain. The Government must ensure that dependable funding is provided to maintain such facilities safely. The new regulatory framework to be introduced in the wake of the Pirbright outbreak is a positive step and should provide a framework in which those operating high containment facilities, given sufficient resources, should be able to continue their work to protect the UK from the threat of infectious disease.

Author : Great Britain: Parliament: House of Commons: Innovation, Universities, Science and Skills Committee
Publisher : The Stationery Office
Page : 188 pages
File Size : 44,7 Mb
Release : 2008
Category : Political Science
ISBN : 0215521250

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Biosecurity in UK Research Laboratories by Great Britain: Parliament: House of Commons: Innovation, Universities, Science and Skills Committee Pdf

Biosecurity in UK research Laboratories : Sixth report of session 2007-08, Vol. 2: Oral and written Evidence

Author : Great Britain. Parliament House of Commons. Innovation, Universities, Science and Skills Committee
Publisher : Unknown
Page : 19 pages
File Size : 53,5 Mb
Release : 2008-11-27
Category : Biological laboratories
ISBN : 0215525272

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Biosecurity in UK Research Laboratories by Great Britain. Parliament House of Commons. Innovation, Universities, Science and Skills Committee Pdf

Government response to HC 360-I, session 2007-08 (ISBN 9780215521248)

Author : Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories,Board on Life Sciences,Committee on International Security and Arms Control,Division on Earth and Life Studies,Policy and Global Affairs,National Academy of Sciences,National Research Council
Publisher : National Academies Press
Page : 216 pages
File Size : 43,8 Mb
Release : 2012-03-16
Category : Political Science
ISBN : 9780309225762

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Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories by Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories,Board on Life Sciences,Committee on International Security and Arms Control,Division on Earth and Life Studies,Policy and Global Affairs,National Academy of Sciences,National Research Council Pdf

During July 10-13, 2011, 68 participants from 32 countries gathered in Istanbul, Turkey for a workshop organized by the United States National Research Council on Anticipating Biosecurity Challenges of the Global Expansion of High-containment Biological Laboratories. The United States Department of State's Biosecurity Engagement Program sponsored the workshop, which was held in partnership with the Turkish Academy of Sciences. The international workshop examined biosafety and biosecurity issues related to the design, construction, maintenance, and operation of high-containment biological laboratories- equivalent to United States Centers for Disease Control and Prevention biological safety level 3 or 4 labs. Although these laboratories are needed to characterize highly dangerous human and animal pathogens, assist in disease surveillance, and produce vaccines, they are complex systems with inherent risks. Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories summarizes the workshop discussion, which included the following topics: Technological options to meet diagnostic, research, and other goals; Laboratory construction and commissioning; Operational maintenance to provide sustainable capabilities, safety, and security; and Measures for encouraging a culture of responsible conduct. Workshop attendees described the history and current challenges they face in their individual laboratories. Speakers recounted steps they were taking to improve safety and security, from running training programs to implementing a variety of personnel reliability measures. Many also spoke about physical security, access controls, and monitoring pathogen inventories. Workshop participants also identified tensions in the field and suggested possible areas for action.

Author : Dawn P. Wooley,Karen B. Byers
Publisher : John Wiley & Sons
Page : 300 pages
File Size : 50,7 Mb
Release : 2020-07-02
Category : Science
ISBN : 9781555819637

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Biological Safety by Dawn P. Wooley,Karen B. Byers Pdf

Biological safety and biosecurity protocols are essential to the reputation and responsibility of every scientific institution, whether research, academic, or production. Every risk—no matter how small—must be considered, assessed, and properly mitigated. If the science isn't safe, it isn't good. Now in its fifth edition, Biological safety: Principles and Practices remains the most comprehensive biosafety reference. Led by editors Karen Byers and Dawn Wooley, a team of expert contributors have outlined the technical nuts and bolts of biosafety and biosecurity within these pages. This book presents the guiding principles of laboratory safety, including: the identification, assessment, and control of the broad variety of risks encountered in the lab; the production facility; and, the classroom. Specifically, Biological Safety covers protection and control elements—from biosafety level cabinets and personal protection systems to strategies and decontamination methods administrative concerns in biorisk management, including regulations, guidelines, and compliance various aspects of risk assessment covering bacterial pathogens, viral agents, mycotic agents, protozoa and helminths, gene transfer vectors, zooonotic agents, allergens, toxins, and molecular agents as well as decontamination, aerobiology, occupational medicine, and training A resource for biosafety professionals, instructors, and those who work with pathogenic agents in any capacity, Biological safety is also a critical reference for laboratory managers, and those responsible for managing biohazards in a range of settings, including basic and agricultural research, clinical laboratories, the vivarium, field study, insectories, and greenhouses.

Author : Anonim
Publisher : Unknown
Page : 66 pages
File Size : 51,6 Mb
Release : 1990
Category : Biological laboratories
ISBN : OCLC:61637633

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Laboratory Biosafety Guidelines by Anonim Pdf

Author : Reynolds M. Salerno,Jennifer Gaudioso
Publisher : CRC Press
Page : 264 pages
File Size : 47,6 Mb
Release : 2015-12-01
Category : Medical
ISBN : 9781498749749

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Laboratory Biorisk Management by Reynolds M. Salerno,Jennifer Gaudioso Pdf

Over the past two decades bioscience facilities worldwide have experienced multiple safety and security incidents, including many notable incidents at so-called "sophisticated facilities" in North America and Western Europe. This demonstrates that a system based solely on biosafety levels and security regulations may not be sufficient. Setting the stage for a substantively different approach for managing the risks of working with biological agents in laboratories, Laboratory Biorisk Management: Biosafety and Biosecurity introduces the concept of biorisk management—a new paradigm that encompasses both laboratory biosafety and biosecurity. The book also provides laboratory managers and directors with the information and technical tools needed for its implementation. The basis for this new paradigm is a three-pronged, multi-disciplinary model of assessment, mitigation, and performance (the AMP model). The application of the methodologies, criteria, and guidance outlined in the book helps to reduce the risk of laboratories becoming the sources of infectious disease outbreaks. This is a valuable resource for those seeking to embrace and implement biorisk management systems in their facilities and operations, including the biological research, clinical diagnostic, and production/manufacturing communities.

Author : Centers for Disease Control (U.S.)
Publisher : Unknown
Page : 156 pages
File Size : 55,8 Mb
Release : 1988
Category : Accidents
ISBN : WISC:89030643761

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Biosafety in Microbiological and Biomedical Laboratories by Centers for Disease Control (U.S.) Pdf

Author : Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on Hazardous Biological Substances in the Laboratory,National Research Council
Publisher : National Academies Press
Page : 237 pages
File Size : 53,9 Mb
Release : 1989-01-01
Category : Science
ISBN : 9780309039758

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Biosafety in the Laboratory by Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on Hazardous Biological Substances in the Laboratory,National Research Council Pdf

Biosafety in the Laboratory is a concise set of practical guidelines for handling and disposing of biohazardous material. The consensus of top experts in laboratory safety, this volume provides the information needed for immediate improvement of safety practices. It discusses high- and low-risk biological agents (including the highest-risk materials handled in labs today), presents the "seven basic rules of biosafety," addresses special issues such as the shipping of dangerous materials, covers waste disposal in detail, offers a checklist for administering laboratory safetyâ€"and more.

Author : Manfred Weidmann,Nigel Silmann,Patrick Butaye,Mandy Elschner
Publisher : John Wiley & Sons
Page : 0 pages
File Size : 41,5 Mb
Release : 2013-12-04
Category : Science
ISBN : 352733467X

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Working in Biosafety Level 3 and 4 Laboratories by Manfred Weidmann,Nigel Silmann,Patrick Butaye,Mandy Elschner Pdf

The first training manual for new staff working in BSL3/4 labs. This guide is based on a course developed in 2007 by the EU COST action group 28b which serves as a standard for many courses BSL3/4 training courses worldwide. The four-day course consists of lectures and practical training with the lecturers covering all the different possibilities of organising a BSL-3/4 lab including the adaptation to the local requirements of biosafety, safety at work, and social regulations. This book covers bio-containment, hazard criteria and categorisation of microbes, technical specifications of BSL-3 laboratories and ABSL-3 laboratories, personal protective gear, shipping BSL-3 and BSL-4 organisms according to UN and IATA regulations, efficacy of inactivation procedures, fumigation, learning from a history of lab accidents, handling samples that arrive for diagnostic testing and bridging the gap between the requirements of bio-containment and diagnostics. Course participants can not only use the book for their actual training event but it will remain a useful reference throughout their career in BSL3/4 labs.

Author : Reynolds M. Salerno,Jennifer Gaudioso,Benjamin H. Brodsky
Publisher : CRC Press
Page : 0 pages
File Size : 47,7 Mb
Release : 2007-06-21
Category : Science
ISBN : 0849364752

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Laboratory Biosecurity Handbook by Reynolds M. Salerno,Jennifer Gaudioso,Benjamin H. Brodsky Pdf

By achieving a delicate balance between systems and practices, proper laboratory biosecurity reduces the risk of legitimate bioscience facilities becoming sources of pathogens and toxins for malicious use. Effective design and implementation of laboratory biosecurity depends on cooperation among individuals from diverse communities, including scientists, technicians, policy makers, security engineers, and law enforcement officials. Providing guidance to the broad international community, Laboratory Biosecurity Handbook addresses the objectives of biosecurity and the ways in which they overlap or conflict with those of biosafety. The book describes the risks of working with dangerous pathogens and toxins in the current era of international terrorism. The authors characterize the global spread of legitimate biotechnology and relate it to the rise of transnational terrorism, emphasizing the need for biosecurity measures even in legitimate bioscience. The book discusses biosecurity risk assessment-a practical methodology that allows laboratory management and biosafety/biosecurity officers to analyze and determine the level of risk, and serves as a basis for managing those risks. The book includes questionnaires that can assist the process of collecting data for a biosecurity vulnerability assessment, example standard operating procedures and memoranda of understanding, and other useful reference material. Addressing a variety of operating environments and the particular challenges they face when designing and implementing laboratory biosecurity, this book can assist bioscience facilities ranging from the large to the small, from those that focus on diagnosis or vaccine development, to those only minimally involved with infectious diseases. The detailed recommendations help avoid a "one-size-fits-all" approach to security and save limited resources. The book shows institutions how to develop and implement a biosecurity plan, and helps ensure that all components are included in the overall system, whether existing or new.

Author : World Health Organization
Publisher : World Health Organization
Page : 196 pages
File Size : 49,9 Mb
Release : 2004-12-28
Category : Medical
ISBN : 9241546506

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Laboratory Biosafety Manual by World Health Organization Pdf

This is the third edition of this manual which contains updated practical guidance on biosafety techniques in laboratories at all levels. It is organised into nine sections and issues covered include: microbiological risk assessment; lab design and facilities; biosecurity concepts; safety equipment; contingency planning; disinfection and sterilisation; the transport of infectious substances; biosafety and the safe use of recombinant DNA technology; chemical, fire and electrical safety aspects; safety organisation and training programmes; and the safety checklist.

Author : Great Britain: Department for Environment, Food and Rural Affairs,Iain Anderson
Publisher : The Stationery Office
Page : 144 pages
File Size : 54,8 Mb
Release : 2008-03-11
Category : Political Science
ISBN : 0102953228

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Foot and mouth disease 2007 by Great Britain: Department for Environment, Food and Rural Affairs,Iain Anderson Pdf

The 2001 outbreak of Foot and Mouth was set out in a report published in 2002, providing an analysis of what happened with recommendations (HCP 888, session 2001-02, ISBN 9780102976243). Another FMD outbreak occurred in the Summer of 2007 and the Government again asked Dr Iain Anderson to conduct a review and find out if the lessons of 2001 had been learned and whether new recommendations are needed. This report is built around the findings of 2001, with a particular look at the Pirbright facility, the source of the virus incriminated in this recent outbreak. Dr Anderson's states that he found much to applaud in the handling of the 2007 outbreak along with some deficiencies, but states the positive outweighs the negative. The report commends the strong leadership of the Prime Minister, as well as the contingency planning and better integration of scientific advice and the capabilities at the centre of disease control strategies. External communication was also greatly improved. Less encouraging were the inadequate infrastructure and governance of the Pirbright facility where the Institute for Animal Health is located and the poor regulatory regime in place to licence work with dangerous animal pathogens. Defra's information systems too were found wanting. The report also recommends that the Institute of Animal Health should become the new National Institute of Infectious Diseases, supported by multiple sources of funding from government and elsewhere. Also recommended is the creation of an Independent Advisory Committee on Animal and Emerging Infectious Diseases, combining a high level group of experts along with other stakeholders with a mission to provide independent advice to government and link closely with the Government's and departmental Chief Scientific Advisors and include the Chief Veterinary Office and Chief Medical Officer amongst its members. The publication is divided into five sections: Section 1: Foreword; Section 2: Summary and recommendations; Section 3: Lessons learned, the lessons are - Lesson 1: Maintain vigilance; Lesson 2: Be prepared; Lesson 3: React with speed and certainty; Lesson 4: Explain policies, plans and practices; Lesson 5: Respect local knowledge; Lesson 6: Apply risk assessment and cost benefit analysis; Lesson 7: Use data and information management systems; Lesson 8: Have a legislative framework; Lesson 9: Base policy decisions on the best available science; Section 4: Pirbright; Section 5: Appendices.

Author : Great Britain: Parliament: House of Commons: Science and Technology Committee,Great Britain. Parliament. House of Commons. Select Committee on Science and Technology
Publisher : The Stationery Office
Page : 130 pages
File Size : 40,8 Mb
Release : 2011-05-25
Category : Research
ISBN : 0215559819

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Uk Centre for Medical Research and Innovation (Ukcmri) by Great Britain: Parliament: House of Commons: Science and Technology Committee,Great Britain. Parliament. House of Commons. Select Committee on Science and Technology Pdf

The Science and Technology Committee today agrees with, and commends, the scientific vision for the new UK Centre for Medical Research and Innovation, but expresses reservations about the project's location. It says the case for the centre's central London location near St Pancras station was not overwhelming and it could have been sited elsewhere. The advantages of co-location with universities and hospitals and access to good transport links, which the Committee accepts play a fundamental role in the centre's vision, come at a price: extra construction costs; a site incapable of expansion; and the concentration of medical sciences in the 'golden triangle' in the south of England. On the issue of funding, the Committee's concerns about the project's costs were assuaged by evidence from the Government that the taxpayer will not be liable to any further costs should the project overrun. On the management structure, the committee was told that an experienced team with a proven track record were now taking charge. The Committee is sympathetic to the local community's concerns about the project, and recognises attempts made by the centre's management to engage with the local community, but says it is saddened that efforts have not been as successful as they might have been. One way some benefit could accrue back to the local community is to ensure that the land released from the National Temperance Hospital site (the original site intended for the UKCMRI) is used for housing, including social housing.

Author : Dr B Usharani,Dr S Anbazhagi,Dr C K Vidya Raj
Publisher : Notion Press
Page : 384 pages
File Size : 53,7 Mb
Release : 2019-07-26
Category : Electronic
ISBN : 1645878856

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Biosafety in Microbiological Laboratories by Dr B Usharani,Dr S Anbazhagi,Dr C K Vidya Raj Pdf

The book describes how to handle hazardous materials in various Biosafety levels, use microbiological good laboratory practices and maintenance of various biosafety cabinets. It is written with the needs of biosafety and biosecurity in mind. The same procedure is fully applicable whenever biohazard materials are handled in life science laboratories. The manual encourages persons who engage in the microbiology laboratory to accept and implement basic concepts in biological safety and to develop national codes of practice for the safe handling of pathogenic microorganisms in laboratories within their geographical borders. It provides international leadership in biosafety by addressing biological safety and security issues facing us in the current millennium. This book stresses the importance of personal responsibility, risk assessment, safe use of recombinant DNA technology, and transport of infectious materials. Recent world events have revealed new threats to public health through deliberate misuse and release of microbiological agents and toxins. The book introduces biosecurity concepts - the protection of microbiological assets from theft, loss, or diversion, which could lead to the inappropriate use of these agents to cause public health harm.