Host And Pathogen Mechanisms Underpinning Viral Ecology And Emerging Infections

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Host And Pathogen Mechanisms Underpinning Viral Ecology And Emerging Infections

Author : Declan C. Schroeder,Jim L. Van Etten,Ian M. Jones,Janusz Tadeusz Paweska,Zhengli Shi,Ahmed Sayed Abdel-Moneim
Publisher : Frontiers Media SA
Page : 427 pages
File Size : 54,6 Mb
Release : 2021-02-24
Category : Science
ISBN : 9782889665068

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Host And Pathogen Mechanisms Underpinning Viral Ecology And Emerging Infections by Declan C. Schroeder,Jim L. Van Etten,Ian M. Jones,Janusz Tadeusz Paweska,Zhengli Shi,Ahmed Sayed Abdel-Moneim Pdf

Wildlife Disease Ecology

Author : Kenneth Wilson,Andy Fenton,Dan Tompkins
Publisher : Cambridge University Press
Page : 693 pages
File Size : 41,9 Mb
Release : 2019-11-14
Category : Mathematics
ISBN : 9781107136564

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Wildlife Disease Ecology by Kenneth Wilson,Andy Fenton,Dan Tompkins Pdf

Introduces readers to key case studies that illustrate how theory and data can be integrated to understand wildlife disease ecology.

Global Health Impacts of Vector-Borne Diseases

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 397 pages
File Size : 50,9 Mb
Release : 2016-10-21
Category : Medical
ISBN : 9780309377591

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Global Health Impacts of Vector-Borne Diseases by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Forum on Microbial Threats Pdf

Pathogens transmitted among humans, animals, or plants by insects and arthropod vectors have been responsible for significant morbidity and mortality throughout recorded history. Such vector-borne diseases â€" including malaria, dengue, yellow fever, and plague â€" together accounted for more human disease and death in the 17th through early 20th centuries than all other causes combined. Over the past three decades, previously controlled vector-borne diseases have resurged or reemerged in new geographic locations, and several newly identified pathogens and vectors have triggered disease outbreaks in plants and animals, including humans. Domestic and international capabilities to detect, identify, and effectively respond to vector-borne diseases are limited. Few vaccines have been developed against vector-borne pathogens. At the same time, drug resistance has developed in vector-borne pathogens while their vectors are increasingly resistant to insecticide controls. Furthermore, the ranks of scientists trained to conduct research in key fields including medical entomology, vector ecology, and tropical medicine have dwindled, threatening prospects for addressing vector-borne diseases now and in the future. In June 2007, as these circumstances became alarmingly apparent, the Forum on Microbial Threats hosted a workshop to explore the dynamic relationships among host, pathogen(s), vector(s), and ecosystems that characterize vector-borne diseases. Revisiting this topic in September 2014, the Forum organized a workshop to examine trends and patterns in the incidence and prevalence of vector-borne diseases in an increasingly interconnected and ecologically disturbed world, as well as recent developments to meet these dynamic threats. Participants examined the emergence and global movement of vector-borne diseases, research priorities for understanding their biology and ecology, and global preparedness for and progress toward their prevention, control, and mitigation. This report summarizes the presentations and discussions from the workshop.

Microbial Evolution and Co-Adaptation

Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 330 pages
File Size : 42,8 Mb
Release : 2009-05-10
Category : Science
ISBN : 9780309131216

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Microbial Evolution and Co-Adaptation by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf

Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.

Infectious Disease Ecology

Author : Richard S. Ostfeld,Felicia Keesing,Valerie T. Eviner
Publisher : Princeton University Press
Page : 520 pages
File Size : 53,6 Mb
Release : 2010-12-16
Category : Science
ISBN : 9781400837885

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Infectious Disease Ecology by Richard S. Ostfeld,Felicia Keesing,Valerie T. Eviner Pdf

News headlines are forever reporting diseases that take huge tolls on humans, wildlife, domestic animals, and both cultivated and native plants worldwide. These diseases can also completely transform the ecosystems that feed us and provide us with other critical benefits, from flood control to water purification. And yet diseases sometimes serve to maintain the structure and function of the ecosystems on which humans depend. Gathering thirteen essays by forty leading experts who convened at the Cary Conference at the Institute of Ecosystem Studies in 2005, this book develops an integrated framework for understanding where these diseases come from, what ecological factors influence their impacts, and how they in turn influence ecosystem dynamics. It marks the first comprehensive and in-depth exploration of the rich and complex linkages between ecology and disease, and provides conceptual underpinnings to understand and ameliorate epidemics. It also sheds light on the roles that diseases play in ecosystems, bringing vital new insights to landscape management issues in particular. While the ecological context is a key piece of the puzzle, effective control and understanding of diseases requires the interaction of professionals in medicine, epidemiology, veterinary medicine, forestry, agriculture, and ecology. The essential resource on the subject, Infectious Disease Ecology seeks to bridge these fields with an ecological approach that focuses on systems thinking and complex interactions.

Emerging Infectious Diseases

Author : Anonim
Publisher : Unknown
Page : 1048 pages
File Size : 52,9 Mb
Release : 2005
Category : Communicable diseases
ISBN : UGA:32108039517480

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Emerging Infectious Diseases by Anonim Pdf

Improving Food Safety Through a One Health Approach

Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 418 pages
File Size : 54,9 Mb
Release : 2012-09-10
Category : Medical
ISBN : 9780309259361

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Improving Food Safety Through a One Health Approach by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf

Globalization of the food supply has created conditions favorable for the emergence, reemergence, and spread of food-borne pathogens-compounding the challenge of anticipating, detecting, and effectively responding to food-borne threats to health. In the United States, food-borne agents affect 1 out of 6 individuals and cause approximately 48 million illnesses, 128,000 hospitalizations, and 3,000 deaths each year. This figure likely represents just the tip of the iceberg, because it fails to account for the broad array of food-borne illnesses or for their wide-ranging repercussions for consumers, government, and the food industry-both domestically and internationally. A One Health approach to food safety may hold the promise of harnessing and integrating the expertise and resources from across the spectrum of multiple health domains including the human and veterinary medical and plant pathology communities with those of the wildlife and aquatic health and ecology communities. The IOM's Forum on Microbial Threats hosted a public workshop on December 13 and 14, 2011 that examined issues critical to the protection of the nation's food supply. The workshop explored existing knowledge and unanswered questions on the nature and extent of food-borne threats to health. Participants discussed the globalization of the U.S. food supply and the burden of illness associated with foodborne threats to health; considered the spectrum of food-borne threats as well as illustrative case studies; reviewed existing research, policies, and practices to prevent and mitigate foodborne threats; and, identified opportunities to reduce future threats to the nation's food supply through the use of a "One Health" approach to food safety. Improving Food Safety Through a One Health Approach: Workshop Summary covers the events of the workshop and explains the recommendations for future related workshops.

Considerations for Viral Disease Eradication

Author : Institute of Medicine,Board on Global Health,Forum on Emerging Infections
Publisher : National Academies Press
Page : 233 pages
File Size : 50,9 Mb
Release : 2002-08-18
Category : Medical
ISBN : 9780309084147

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Considerations for Viral Disease Eradication by Institute of Medicine,Board on Global Health,Forum on Emerging Infections Pdf

Since smallpox eradication, the science of eradication has changed and with it, our definitions of what diseases are possible to eradicate. However, eradication must not beget complacency. As has been learned from past control or eradication attempts with a variety of viral diseases, from yellow fever to influenza, accidental or intentional reintroduction is a real threat-one that could strike anywhere and for which we need to be fully prepared. The criteria for assessing eradicability of polio, measles, and other viral infections have been debated extensively. With the elimination and eradication of several viral diseases on the horizon, issues surrounding the cessation of immunization activities become exceedingly important. In an effort to better understand the dynamics of disease eradication and post-immunization policies, the Institute of Medicine Forum on Emerging Infections hosted a two-day workshop (February 1-2, 2001) on The Consequences of Viral Disease Eradication. This book explores the principles underlying the biological challenges, medical interventions, the continuing research agenda, and operational considerations for post-immunization strategies for vaccine-preventable viral diseases, and highlights important efforts that may facilitate wise decision making.

Roles and mechanisms of parasitism in aquatic microbial communities

Author : Télesphore Sime-Ngando,Kevin D. Lafferty,David G. Biron
Publisher : Frontiers Media SA
Page : 155 pages
File Size : 54,5 Mb
Release : 2015-07-24
Category : Microbiology
ISBN : 9782889195886

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Roles and mechanisms of parasitism in aquatic microbial communities by Télesphore Sime-Ngando,Kevin D. Lafferty,David G. Biron Pdf

Next Generation Sequencing technologies are increasingly revealing that microbial taxa likely to be parasites or symbionts are probably much more prevalent and diverse than previously thought. Every well studied free-living species has parasites; parasites themselves can be parasitized. As a rule of thumb, there is an estimated 4 parasitic species for any given host, and the better a host is studied the more parasites are known to infect it. Therefore, parasites and other symbionts should represent a very large number of species and may far outnumber those with 'free-living' lifestyles. Paradoxically, free-living hosts, which form the bulk of our knowledge of biology, may be a minority! Microbial parasites typically are characterized by their small size, short generation time, and high rates of reproduction, with simple life cycle occurring generally within a single host. They are diverse and ubiquitous in the environment, comprising viruses, prokaryotes and eukaryotes. This Frontiers Research Topic sought to provide a broad overview but concise, comprehensive, well referenced and up-to-date state of the art for everyone involved with microbial parasites in aquatic microbial ecology.

Microbial Ecology in States of Health and Disease

Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 548 pages
File Size : 43,9 Mb
Release : 2014-02-18
Category : Medical
ISBN : 9780309290654

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Microbial Ecology in States of Health and Disease by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf

Individually and collectively, resident microbes play important roles in host health and survival. Shaping and shaped by their host environments, these microorganisms form intricate communities that are in a state of dynamic equilibrium. This ecologic and dynamic view of host-microbe interactions is rapidly redefining our view of health and disease. It is now accepted that the vast majority of microbes are, for the most part, not intrinsically harmful, but rather become established as persistent, co-adapted colonists in equilibrium with their environment, providing useful goods and services to their hosts while deriving benefits from these host associations. Disruption of such alliances may have consequences for host health, and investigations in a wide variety of organisms have begun to illuminate the complex and dynamic network of interaction - across the spectrum of hosts, microbes, and environmental niches - that influence the formation, function, and stability of host-associated microbial communities. Microbial Ecology in States of Health and Disease is the summary of a workshop convened by the Institute of Medicine's Forum on Microbial Threats in March 2013 to explore the scientific and therapeutic implications of microbial ecology in states of health and disease. Participants explored host-microbe interactions in humans, animals, and plants; emerging insights into how microbes may influence the development and maintenance of states of health and disease; the effects of environmental change(s) on the formation, function, and stability of microbial communities; and research challenges and opportunities for this emerging field of inquiry.

The Emergence of Zoonotic Diseases

Author : Institute of Medicine,Board on Global Health,Forum on Emerging Infections
Publisher : National Academies Press
Page : 176 pages
File Size : 48,5 Mb
Release : 2002-04-09
Category : Medical
ISBN : 9780309169738

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The Emergence of Zoonotic Diseases by Institute of Medicine,Board on Global Health,Forum on Emerging Infections Pdf

Zoonotic diseases represent one of the leading causes of illness and death from infectious disease. Defined by the World Health Organization, zoonoses are "those diseases and infections that are naturally transmitted between vertebrate animals and man with or without an arthropod intermediate." Worldwide, zoonotic diseases have a negative impact on commerce, travel, and economies. In most developing countries, zoonotic diseases are among those diseases that contribute significantly to an already overly burdened public health system. In industrialized nations, zoonotic diseases are of particular concern for at-risk groups such as the elderly, children, childbearing women, and immunocompromised individuals. The Emergence of Zoonotic Diseases: Understanding the Impact on Animal and Human Health, covers a range of topics, which include: an evaluation of the relative importance of zoonotic diseases against the overall backdrop of emerging infections; research findings related to the current state of our understanding of zoonotic diseases; surveillance and response strategies to detect, prevent, and mitigate the impact of zoonotic diseases on human health; and information about ongoing programs and actions being taken to identify the most important needs in this vital area.

Microbial Threats to Health

Author : Institute of Medicine,Board on Global Health,Committee on Emerging Microbial Threats to Health in the 21st Century
Publisher : National Academies Press
Page : 397 pages
File Size : 48,5 Mb
Release : 2003-08-25
Category : Medical
ISBN : 9780309185547

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Microbial Threats to Health by Institute of Medicine,Board on Global Health,Committee on Emerging Microbial Threats to Health in the 21st Century Pdf

Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.

Global Infectious Disease Surveillance and Detection

Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 284 pages
File Size : 45,8 Mb
Release : 2007-11-11
Category : Medical
ISBN : 9780309111140

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Global Infectious Disease Surveillance and Detection by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf

Early detection is essential to the control of emerging, reemerging, and novel infectious diseases, whether naturally occurring or intentionally introduced. Containing the spread of such diseases in a profoundly interconnected world requires active vigilance for signs of an outbreak, rapid recognition of its presence, and diagnosis of its microbial cause, in addition to strategies and resources for an appropriate and efficient response. Although these actions are often viewed in terms of human public health, they also challenge the plant and animal health communities. Surveillance, defined as "the continual scrutiny of all aspects of occurrence and spread of a disease that are pertinent to effective control", involves the "systematic collection, analysis, interpretation, and dissemination of health data." Disease detection and diagnosis is the act of discovering a novel, emerging, or reemerging disease or disease event and identifying its cause. Diagnosis is "the cornerstone of effective disease control and prevention efforts, including surveillance." Disease surveillance and detection relies heavily on the astute individual: the clinician, veterinarian, plant pathologist, farmer, livestock manager, or agricultural extension agent who notices something unusual, atypical, or suspicious and brings this discovery in a timely way to the attention of an appropriate representative of human public health, veterinary medicine, or agriculture. Most developed countries have the ability to detect and diagnose human, animal, and plant diseases. Global Infectious Disease Surveillance and Detection: Assessing the Challenges-Finding Solutions, Workshop Summary is part of a 10 book series and summarizes the recommendations and presentations of the workshop.

Health of Antarctic Wildlife

Author : Knowles R. Kerry,Martin Riddle
Publisher : Springer Science & Business Media
Page : 470 pages
File Size : 47,8 Mb
Release : 2009-07-29
Category : Science
ISBN : 9783540939238

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Health of Antarctic Wildlife by Knowles R. Kerry,Martin Riddle Pdf

comprehensively up to date. We are most grateful to these authors and to those we recruited to write the additional chapters necessary to fill the significant gaps. We acknowledge also the sacrifice of some who presented results of original research and have thus suffered a longer time than usual to publication. The timing of publication however has provided the opportunity to highlight recent discussions and resolutions made within the Antarctic Treaty forum to protect wildlife against disease and to include responses by Government and non-Government operators in Antarctica. These developments mostly followed from the Workshop on Diseases of Antarctic Wildlife. The book comprises 17 chapters presented in two parts. Wildlife disease consists of reviews, case studies and health assessments, and External factors covers the environmental, administrative and legal aspects. Each chapter is complete and c- tains all references. Six important documents are provided as Appendices. These present methods, reviews and other documents which are referred to in one or more chapters but are not readily available. There are many related topics we have been unable to cover that would enhance the understanding of health and disease processes in Antarctica. While we ackno- edge their importance they are outside the scope of the present volume. Such topics include epidemiology, new and emerging infectious diseases and the effects of climate change. These topics are referred to in the various chapters where ref- ences to source material are given.

Molecular Virology of Human Pathogenic Viruses

Author : Wang-Shick Ryu
Publisher : Academic Press
Page : 440 pages
File Size : 48,8 Mb
Release : 2016-03-30
Category : Science
ISBN : 9780128009994

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Molecular Virology of Human Pathogenic Viruses by Wang-Shick Ryu Pdf

Molecular Virology of Human Pathogenic Viruses presents robust coverage of the key principles of molecular virology while emphasizing virus family structure and providing key context points for topical advances in the field. The book is organized in a logical manner to aid in student discoverability and comprehension and is based on the author’s more than 20 years of teaching experience. Each chapter will describe the viral life cycle covering the order of classification, virion and genome structure, viral proteins, life cycle, and the effect on host and an emphasis on virus-host interaction is conveyed throughout the text. Molecular Virology of Human Pathogenic Viruses provides essential information for students and professionals in virology, molecular biology, microbiology, infectious disease, and immunology and contains outstanding features such as study questions and recommended journal articles with perspectives at the end of each chapter to assist students with scientific inquiries and in reading primary literature. Presents viruses within their family structure Contains recommended journal articles with perspectives to put primary literature in context Includes integrated recommended reading references within each chapter Provides access to online ancillary package inclusive of annotated PowerPoint images, instructor’s manual, study guide, and test bank