Human Fetal Tissue Transplantation

Author : Niranjan Bhattacharya,Phillip Stubblefield
Publisher : Springer Science & Business Media
Page : 467 pages
File Size : 42,7 Mb
Release : 2013-02-26
Category : Medical
ISBN : 9781447141716

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Human Fetal Tissue Transplantation by Niranjan Bhattacharya,Phillip Stubblefield Pdf

Many diseases earlier considered to be incurable are now being treated with modern innovations involving fetal tissue transplants and stem cells derived from fetal tissues. Fetal tissues are the richest source of fetal stem cells as well as other varying states of differentiated cells and support or stromal cells. The activity of such stem cells is at their peak provided they are given the correct niche. Stem cells, as we know, are immortal cells with the capacity to regenerate into any kind of differentiated cell as per niche-guidance. As such, fetal tissues have the potential capacity to mend, regenerate and repair damaged cells or tissues in adults, when directly transplanted to the site of injury, or even when transplanted in some other site, because it may have a homing capacity to migrate to the site of the specific injured organ. This is a new area of translational research and needs to be highlighted because of its immense potential. This book will bring together the new work of prominent medical scientists and clinicians who are conducting pioneering research in human fetal tissue transplantation. This will include direct transplant of healthy fetal tissue into mature patients as well as in hosts with genetic diseases. Transplant techniques, donor-host interaction, cell and tissue storage, ethical and legal issues, are some of the many matters which the book will deal with.

Author : Advisory Committee to the Director, National Institutes of Health
Publisher : Unknown
Page : 76 pages
File Size : 46,6 Mb
Release : 1988
Category : Abortion
ISBN : UCLA:L0061546958

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Human Fetal Tissue Transplantation Research by Advisory Committee to the Director, National Institutes of Health Pdf

Author : Robert G. Edwards
Publisher : Cambridge University Press
Page : 367 pages
File Size : 54,5 Mb
Release : 1992-11-05
Category : Medical
ISBN : 9780521410755

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Fetal Tissue Transplants in Medicine by Robert G. Edwards Pdf

The most recent scientific and clinical developments and techniques in fetal tissue transplants are presented, including both the transplantation of fetal tissue into mature recipients, and the grafting of donor cells into fetuses that are known to be carrying genetic disease.

Author : United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Health and the Environment
Publisher : Unknown
Page : 224 pages
File Size : 54,9 Mb
Release : 1990
Category : Fetal membranes
ISBN : PSU:000019452944

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Fetal Tissue Transplantation Research by United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Health and the Environment Pdf

Author : United States. Congress. Senate. Committee on Labor and Human Resources
Publisher : Unknown
Page : 144 pages
File Size : 45,8 Mb
Release : 1992
Category : Law
ISBN : LOC:00061278060

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Finding Medical Cures by United States. Congress. Senate. Committee on Labor and Human Resources Pdf

Author : Institute of Medicine,Conference Committee on Fetal Research and Applications
Publisher : National Academies Press
Page : 116 pages
File Size : 41,9 Mb
Release : 1994-02-01
Category : Medical
ISBN : 9780309051767

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Fetal Research and Applications by Institute of Medicine,Conference Committee on Fetal Research and Applications Pdf

Research involving human fetuses and fetal tissue has been a subject of national debate and rancor for more than two decades. Despite the many demonstrated medical benefits of such research and the issuance of guidelines by various governmental and private ethics advisory bodies, federal support of this research has been severely curtailed. In 1993 the Institute of Medicine (IOM) sponsored a conference on fetal research and applications. This book examines the current state of fetal research and fetal tissue research. It contains an overview of research in the field and a short history on the regulatory and legislative actions governing the field. The bulk of the volume centers on ethical and legal issues of fetal research, preembryo research, fetal research, and fetal tissue transplantation. The volume also contains a full reprinting of the summary from the 1989 IOM book Medically Assisted Conception: An Agenda for Research, including the recommendations and research agenda suggested in that volume. Readers can therefore view that information in context with the suggestions and topics discussed at the conference. The background and research summarized in Fetal Research and Applications should provide insights for future progress and contribute to a fuller understanding of the social and ethical issues involved in this field.

Author : Canada. Royal Commission on New Reproductive Technologies
Publisher : Canadian Government Publishing
Page : 316 pages
File Size : 52,7 Mb
Release : 1993
Category : Medical
ISBN : UCAL:B4526789

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Background and Current Practice of Fetal Tissue and Embryo Research in Canada by Canada. Royal Commission on New Reproductive Technologies Pdf

These research studies cover human embryo and fetal tissue research, providing a concise overview of the subject; legal issues in embryo and fetal tissue research and therapy; origins, state of the art, future applications, and implications of human fetal tissue research; a survey of use and handling of human reproductive tissues in Canadian health care facilities; a survey of medical laboratories and medical waste disposal firms related to use and handling of human reproductive tissues; embryo transfer and related technologies in domestic animals; and the past, present, and future of human embryo research.

Author : Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research
Publisher : National Academies Press
Page : 112 pages
File Size : 43,8 Mb
Release : 2002-01-25
Category : Science
ISBN : 9780309170420

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Stem Cells and the Future of Regenerative Medicine by Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research Pdf

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Author : Anonim
Publisher : Unknown
Page : 218 pages
File Size : 44,7 Mb
Release : 1999
Category : Bioethics
ISBN : NYPL:33433082965660

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Ethical Issues in Human Stem Cell Research by Anonim Pdf

Author : United States. National Bioethics Advisory Commission
Publisher : Unknown
Page : 158 pages
File Size : 52,6 Mb
Release : 1999
Category : Bioethics
ISBN : IND:30000078910084

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Ethical Issues in Human Stem Cell Research by United States. National Bioethics Advisory Commission Pdf

Author : United States. National Bioethics Advisory Commission
Publisher : Unknown
Page : 216 pages
File Size : 40,5 Mb
Release : 1999
Category : Bioethics
ISBN : MINN:30000006605590

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Ethical Issues in Human Stem Cell Research: Commissioned papers by United States. National Bioethics Advisory Commission Pdf

Author : United States. National Bioethics Advisory Commission
Publisher : Unknown
Page : 140 pages
File Size : 42,8 Mb
Release : 1999
Category : Bioethics
ISBN : PURD:32754069797912

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Ethical Issues in Human Stem Cell Research: Report and recommendations of the National Bioethics Advisory Commission by United States. National Bioethics Advisory Commission Pdf

Author : Peter McCullagh
Publisher : Unknown
Page : 232 pages
File Size : 47,6 Mb
Release : 1987-05
Category : Medical
ISBN : UOM:39015011645234

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The Foetus as Transplant Donor by Peter McCullagh Pdf

The ethical issues sourrounding foetal experimentation have been under constant debate since the early 1970s. This book analyzes all aspects of foetal experimentation and suggests answers to the difficult questions concerning its morality and uses, as well as the difficulties associated with diagnosing foetal brain death. Explores the moral implications of experimental, as opposed to therapeutic, rationales for experimentation on foetal subjects. Also offers historical background on current perceptions of the suitability of foetal tissue for transplantation, how current claims have been derived from earlier practice, and the manner in which proposals for transplantation of one specific type of foetal tissue, the pancreas, have been presented to the community.

Author : National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Committee on Guidelines for Human Embryonic Stem Cell Research
Publisher : National Academies Press
Page : 224 pages
File Size : 55,9 Mb
Release : 2005-09-15
Category : Medical
ISBN : 9780309096539

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Guidelines for Human Embryonic Stem Cell Research by National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Committee on Guidelines for Human Embryonic Stem Cell Research Pdf

Since 1998, the volume of research being conducted using human embryonic stem (hES) cells has expanded primarily using private funds because of restrictions on the use of federal funds for such research. Given limited federal involvement, privately funded hES cell research has thus far been carried out under a patchwork of existing regulations, many of which were not designed with this research specifically in mind. In addition, hES cell research touches on many ethical, legal, scientific, and policy issues that are of concern to the public. This report provides guidelines for the conduct of hES cell research to address both ethical and scientific concerns. The guidelines are intended to enhance the integrity of privately funded hES cell research by encouraging responsible practices in the conduct of that research.

Author : B. Formby,L. JovanovicPeterson,C.M. Peterson
Publisher : Springer Science & Business Media
Page : 344 pages
File Size : 51,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461519812

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Fetal Islet Transplantation by B. Formby,L. JovanovicPeterson,C.M. Peterson Pdf

Despite the advent of insulin for clinical use in 1922, our ability to control hypergly cemia and prevent the long term sequelae ofthe disease remains limited. Thus normalization of the milieu interieur with physiologic responses of insulin and metabolites remains an elusive but critically important goal. The developing endocrine pancreas provides a model system that speaks to many challenges of the transplantation biologist. Thus the attempt to of vascularization, growth and development, immunologic toler recapitulate the ontogeny ance, and glucose responsive insulin secretory capacity of fetal islet tissue provides a tantalizing possibility to replace insulin secreting tissue in persons with diabetes. Studies of this tissue are also important because of the implications such investigations have for genetic and molecular biological approaches to restoring insulin secretion as well as for providing clues to enhancing the growth and repair of islets that have been the target of autoimmune disease. Investigators in the area offetal islet transplantation comprise a small group scattered throughout the world scientific community. Therefore it seemed important to provide a forum where these scientists could gather, share ideas, and achieve consensus such that progress in this rapidly evolving area could be facilitated. The conference would have remained a dream if the support of the Okla Basil Meade, Jr. family had not made it manifest.