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National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on National Monitoring of Human Tissues
Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on National Monitoring of Human Tissues Publisher : National Academies Press Page : 224 pages File Size : 48,5 Mb Release : 1991-02-01 Category : Science ISBN : 9780309044370
Monitoring Human Tissues for Toxic Substances by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on National Monitoring of Human Tissues Pdf
The National Human Monitoring Program (NHMP) identifies concentrations of specific chemicals in human tissues, including toxicologic testing and risk assessment determinations. This volume evaluates the current activities of the NHMP; identifies important scientific, technical, and programmatic issues; and makes recommendations regarding the design of the program and use of its products.
Handbook of Human Tissue Sources. A National Resource of Human Tissue Samples by Anonim Pdf
One aspect of the recent and rapid advances in biological and medical research is that human tissue is being used in an increasing variety of new ways. Now that techniques exist to extract DNA from minuscule archival samples, Including frozen blood or tissue samples and even paraffin-embedded tissue blocks, genetic tests could potentially be performed on virtually any size stored tissue sample. These technological advances, which have been so instrumental in recent biomedical discoveries, have also raised several legal, ethical, and societal issues, including concerns about privacy and informed consent.
The Ethical and Legal Regulation of Human Tissue and Biobank Research in Europe by Nils Hoppe,Silvia Schnorrer,Christian Lenk Pdf
"Human tissue and biobank research is of increasing importance for understanding the causes of widespread diseases and developing effective therapies. However, while the success of biobank research depends on the availability of a large number of samples and the consolidation of collections across country borders is very desirable from the perspective of researchers, the legal and ethical requirements for the procurement, storage and use of human tissue samples are rather heterogeneous across different countries. Moreover, the lack of comprehensive supranational regulation on human tissue and biobanking can be seen as posing a serious threat to transnational biomedical research. Against this background, it was one of the aims of the EU-funded Tiss.EU project ('Evaluation of Legislation and Related Guidelines on the Procurement, Storage and Transfer of Human Tissues and Cells in the European Union--an Evidence-Based Impact Analysis') to analyse the ethical and legal regulation of human tissue and biobank research across the 27 European Member States plus Switzerland. The results of nine international workshops and three conferences are gathered in this volume. While the country reports evaluate the implementation of ethical and legal guidelines at a national level, point out their strengths and deficits, and, where required, create an evidence base for the revision of said legislation, the conference reports address more general ethical and legal issues in this field. The volume is completed by a final presentation of project's results"--Publisher's description
Case Studies of Existing Human Tissue Repositories by Elisa Eiseman,Gabrielle Bloom,Jennifer Brower,Noreen Clancy,Stuart S. Olmsted Pdf
Case studies of twelve existing human biospecimen repositories performed to evaluate their utility for genomics- and proteomics-based cancer research and to identify "best practices" in collection, processing, annotation, storage, privacy, ethical concerns, informed consent, business plans, operations, intellectual property rights, public relations, marketing, and education that would be useful in designing a national biospecimen network.
National Research Council,Commission on Behavioral and Social Sciences and Education,Committee on Population
Author : National Research Council,Commission on Behavioral and Social Sciences and Education,Committee on Population Publisher : National Academies Press Page : 388 pages File Size : 45,9 Mb Release : 2001-01-19 Category : Social Science ISBN : 9780309171434
Cells and Surveys by National Research Council,Commission on Behavioral and Social Sciences and Education,Committee on Population Pdf
What can social science, and demography in particular, reasonably expect to learn from biological information? There is increasing pressure for multipurpose household surveys to collect biological data along with the more familiar interviewer-respondent information. Given that recent technical developments have made it more feasible to collect biological information in non-clinical settings, those who fund, design, and analyze survey data need to think through the rationale and potential consequences. This is a concern that transcends national boundaries. Cells and Surveys addresses issues such as which biologic/genetic data should be collected in order to be most useful to a range of social scientists and whether amassing biological data has unintended side effects. The book also takes a look at the various ethical and legal concerns that such data collection entails.
United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Oversight and Investigations
Author : United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Oversight and Investigations Publisher : Unknown Page : 294 pages File Size : 49,9 Mb Release : 2006 Category : Law ISBN : STANFORD:36105064000248
Michael R. Emmert-Buck,John W. Gillespie,Rodrigo F. Chuaqui
Author : Michael R. Emmert-Buck,John W. Gillespie,Rodrigo F. Chuaqui Publisher : Springer Science & Business Media Page : 239 pages File Size : 49,7 Mb Release : 2005-11-20 Category : Science ISBN : 9783540264828
Dissecting the Molecular Anatomy of Tissue by Michael R. Emmert-Buck,John W. Gillespie,Rodrigo F. Chuaqui Pdf
The book provides an updated overview of molecular analysis of human tissues, and the impact this analysis has on diagnosis and prognosis of human diseases. Special emphasis is placed on human cancer and the future directions of the field. Methods of handling clinical tissue samples, including the impact of handling on subsequent molecular analysis, are also discussed. In addition, detailed protocols for molecular analysis of DNA, RNA and protein, with special emphasis on molecular analysis of highly complex human tissue samples containing mixtures of cell populations, are provided.
Research Involving Human Biological Materials: Commissioned papers. Privacy and the analysis of stored tissues by United States. National Bioethics Advisory Commission Pdf
Author : Robert F. Weir,Robert S. Olick Publisher : Oxford University Press Page : 358 pages File Size : 45,7 Mb Release : 2004-05-20 Category : Medical ISBN : 9780199748846
The Stored Tissue Issue by Robert F. Weir,Robert S. Olick Pdf
Genetics research with stored human tissues provides many benefits and holds much promise. Yet how this critical research is conducted sometimes raises serious ethical, legal, and social concerns, and it is difficult to balance the promise of biomedical research with our time-honored commitments to individual choice in such fundamental matters as control over personal health information and the disposition of our bodily tissues. Weir and Olick provide a thorough analysis of this critical phase in the era of genomic medicine. While strongly supportive of the biomedical research enterprise, they develop a critique of many common research practices with banked tissues, DNA, and genetic data. Noting numerous examples of beneficial human tissue research, they focus on problematic research practices, controversial cases, and federal and institutional policies that limit the informed choices of patients and research participants. The authors offer a series of recommendations intended to limit the risks of inadequate informed consent to research for individuals, families, and groups, and to strengthen the bonds of trust between the research enterprise and the public upon which biomedical progress depends. This book offers a wealth of information plus well-reasoned recommendations that will be of keen interest to geneticists, other biomedical scientists, research institutions, policymakers, students and others. It will serve as a clarion call to move beyond traditional policies and practices toward a richer understanding of partnership between patients and research participants and the biomedical research enterprise - a partnership for the benefit of all.
The use of human tissue for medical research and scientific progress raises many ethical and legal challenges. This multi-authored interdisciplinary text provides a fascinating insight into interlinking research perspectives and serves as a comprehensive reference to the state of play ethically and legally in Europe.
National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population,Committee on National Statistics,Panel on Collecting, Storing, Accessing, and Protecting Biological Specimens and Biodata in Social Surveys
Author : National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population,Committee on National Statistics,Panel on Collecting, Storing, Accessing, and Protecting Biological Specimens and Biodata in Social Surveys Publisher : National Academies Press Page : 124 pages File Size : 47,9 Mb Release : 2010-10-02 Category : Computers ISBN : 9780309157063
Conducting Biosocial Surveys by National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population,Committee on National Statistics,Panel on Collecting, Storing, Accessing, and Protecting Biological Specimens and Biodata in Social Surveys Pdf
Recent years have seen a growing tendency for social scientists to collect biological specimens such as blood, urine, and saliva as part of large-scale household surveys. By combining biological and social data, scientists are opening up new fields of inquiry and are able for the first time to address many new questions and connections. But including biospecimens in social surveys also adds a great deal of complexity and cost to the investigator's task. Along with the usual concerns about informed consent, privacy issues, and the best ways to collect, store, and share data, researchers now face a variety of issues that are much less familiar or that appear in a new light. In particular, collecting and storing human biological materials for use in social science research raises additional legal, ethical, and social issues, as well as practical issues related to the storage, retrieval, and sharing of data. For example, acquiring biological data and linking them to social science databases requires a more complex informed consent process, the development of a biorepository, the establishment of data sharing policies, and the creation of a process for deciding how the data are going to be shared and used for secondary analysis-all of which add cost to a survey and require additional time and attention from the investigators. These issues also are likely to be unfamiliar to social scientists who have not worked with biological specimens in the past. Adding to the attraction of collecting biospecimens but also to the complexity of sharing and protecting the data is the fact that this is an era of incredibly rapid gains in our understanding of complex biological and physiological phenomena. Thus the tradeoffs between the risks and opportunities of expanding access to research data are constantly changing. Conducting Biosocial Surveys offers findings and recommendations concerning the best approaches to the collection, storage, use, and sharing of biospecimens gathered in social science surveys and the digital representations of biological data derived therefrom. It is aimed at researchers interested in carrying out such surveys, their institutions, and their funding agencies.
From the award-winning author of Medical Apartheid, an exposé of the rush to own and exploit the raw materials of life—including yours. Think your body is your own to control and dispose of as you wish? Think again. The United States Patent Office has granted at least 40,000 patents on genes controlling the most basic processes of human life, and more are pending. If you undergo surgery in many hospitals you must sign away ownership rights to your excised tissues, even if they turn out to have medical and fiscal value. Life itself is rapidly becoming a wholly owned subsidiary of the medical-industrial complex. Deadly Monopolies is a powerful, disturbing, and deeply researched book that illuminates this “life patent” gold rush and its harmful, and even lethal, consequences for public health. Like the bestselling The Immortal Life of Henrietta Lacks, it reveals in shocking detail just how far the profit motive has encroached in colonizing human life and compromising medical ethics.
