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Author : Aravinda Chakravarti
Publisher : Unknown
Page : 0 pages
File Size : 54,6 Mb
Release : 2014
Category : Medical
ISBN : 1621820904
"A subject collection from Cold Spring Harbor perspectives in medicine."
Author : C.G. Nicholas Mascie-Taylor,Akira Yasukouchi,Stanley Ulijaszek
Publisher : CRC Press
Page : 317 pages
File Size : 46,7 Mb
Release : 2010-03-17
Category : Science
ISBN : 1420084747
The transition in anthropological and biomedical research methods over the past 50 years, from anthropometric and craniometric measurements to large-scale microarray genetic studies has resulted in continued revision of opinions and ideas relating to the factors and forces that drive human variation. Human Variation:From the Laboratory to the Field brings together the contributions of 22 scientists working in four continents to identify and address challenges imposed by variability. It reviews the way we examine and analyze human variation, paying specific attention to genetics, growth and development, and physiology. In presenting new evidence and findings, it also discusses current developments in methodology and analytical techniques, detailing both field and laboratory approaches, and looking at how the two perspectives complement each other. In bridging that gap between laboratory trials and studies of the human in context, this book covers a number of interesting research areas including — Human adaptation to natural and artificial light, including variations in circadian photosensitivity and effects of light on GI activity Cold tolerance and lifestyle in modern society Genetics of body weight and obesity Human adaptability to emotional and intellectual mental stresses Geography, migration, climate, and environmental plasticity as contributors to human variation Impact of natural environmental stressors including pollution on physiological and morphological processes This book is the latest volume in a series of works from the Society for the Study of Human Biology (SSHB), which for half a century has advanced and promoted research in the biology of human populations in all of its branches including human viability, genetics, human adaptability, and ecology, and evolution. It holds two scientific meetings a year. This volume represents work presented during its most recent gathering.
Author : R. Shane Tubbs,Mohammadali M. Shoja,Marios Loukas
Publisher : John Wiley & Sons
Page : 1452 pages
File Size : 49,6 Mb
Release : 2016-07-12
Category : Science
ISBN : 9781118430354
Building on the strength of the previous two editions, Bergman's Comprehensive Encyclopedia of Human Anatomic Variation is the third installment of the classic human anatomical reference launched by Dr. Ronald Bergman. With both new and updated entries, and now illustrated in full color, the encyclopedia provides an even more comprehensive reference on human variation for anatomists, anthropologists, physicians, surgeons, medical personnel, and all students of anatomy. Developed by a team of editors with extensive records publishing on both human variation and normal human anatomy, Bergman's Comprehensive Encyclopedia of Human Anatomic Variation is the long awaited update to this classic reference.
Author : Phyllis B. Eveleth,James Mourilyan Tanner
Publisher : CUP Archive
Page : 520 pages
File Size : 47,9 Mb
Release : 1976-12-30
Category : Family & Relationships
ISBN : 0521208068
Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Human Genome Diversity
Publisher : National Academies Press
Page : 101 pages
File Size : 50,6 Mb
Release : 1998-01-19
Category : Science
ISBN : 9780309184748
This book assesses the scientific value and merit of research on human genetic differencesâ€"including a collection of DNA samples that represents the whole of human genetic diversityâ€"and the ethical, organizational, and policy issues surrounding such research. Evaluating Human Genetic Diversity discusses the potential uses of such collection, such as providing insight into human evolution and origins and serving as a springboard for important medical research. It also addresses issues of confidentiality and individual privacy for participants in genetic diversity research studies.
Author : Alexandra Widmer,Veronika Lipphardt
Publisher : Berghahn Books
Page : 250 pages
File Size : 43,9 Mb
Release : 2016-09-01
Category : Social Science
ISBN : 9781785332722
Human variation represented a central research topic for life scientists and posed challenging administrative issues for colonial bureaucrats in the first half of the 20th century. By following scientists’ and administrators’ interests in innovating styles and tools for making and circulating documents, in reshaping landscapes and environments, and in fixing distances between humans, the book advances new understandings of the materiality of colonial institutional life and governance.
Author : Stephen Molnar
Publisher : Routledge
Page : 416 pages
File Size : 44,6 Mb
Release : 2015-09-04
Category : Social Science
ISBN : 9781317347729
Basic text for the sophomore/junior level course in Human Variation or Human Diversity taught anthropology or biology departments. This classic introduction to human variation, has been thoroughly updated to include the issues and controversies facing the contemporary study of diversity.
Author : Kenneth M. Weiss
Publisher : Cambridge University Press
Page : 384 pages
File Size : 44,8 Mb
Release : 1993
Category : Medical
ISBN : 0521336600
Recent developments in molecular and computational methods have made it possible to identify the genetic basis of any biological trait, and have led to spectacular advances in the study of human disease. This book provides an overview of the concepts and methods needed to understand the genetic basis of biological traits, including disease, in humans. Using examples of qualitative and quantitative phenotypes, Professor Weiss shows how genetic variation may be quantified, and how relationships between genotype and phenotype may be inferred. This book will appeal to many biologists and biological anthropologists interested in the genetic basis of biological traits, as well as to epidemiologists, biomedical scientists, human geneticists and molecular biologists.
Author : Moyra Smith
Publisher : FT Press
Page : 243 pages
File Size : 47,8 Mb
Release : 2011-06-08
Category : Medical
ISBN : 9780132172844
Leading medical genetics scholar Moyra Smith reviews current and recent work in genetics and genomics to assess progress in understanding human variation and the pathogenesis of common and rare diseases in which genetics plays a role. Smith provides an exceptional overview of the most important biomedical progress arising from the greatly increased genetic information base generated by gene mapping and the sequencing of the complete Human Genome. This book addresses into a wide spectrum of topics associated with human genetics and genomics, including: Human origins; migrations and human population diversity gained though genomic analyses. The complexities of psychiatric diseases that are influenced by genetics. The pathogenesis of late-onset neurological diseases such as Alzheimer’s, Parkinsonism, and ALS. Key aspects of protein misfolding. Gene-environment interactions in DNA damage and repair and DNA instability. Micro RNAs and mRNA translation. Epigenetics. New functions for old enzymes in cancer.
Author : James H. Mielke,Lyle W. Konigsberg,John Relethford
Publisher : Oxford University Press, USA
Page : 443 pages
File Size : 55,5 Mb
Release : 2011
Category : Nature
ISBN : 0195387406
This text explores human biological variation in its broadest sense - from the molecular to the physiological and morphological - focusing on the micro-evolutionary analysis of genetic variation among recent human populations. Authoritative yet accessible, Human Biological Variation, SecondEdition, opens with an engaging introduction to basic genetics and the evolutionary forces that set the stage for understanding human diversity. It goes on to offer a clear and detailed discussion of molecular genetics, including its uses and its relationship to anthropological and evolutionarymodels. The text features up-to-date discussions of classic genetic markers (blood groups, enzymes, and proteins) along with extensive background on DNA analysis and coverage of satellite DNA, single nucleotide polymorphisms (SNPs), and Alu inserts. Coverage includes current issues such as themeaning and significance of "race," quantitative genetics and the "nature versus nurture" debates, biocultural interactions, population structure, and cultural and historical influences on patterns of human variation. Integrating real-world examples on interesting topics - including dyslexia, IQ,and homosexuality - this second edition of Human Biological Variation provides the most thorough and contemporary view of our biological diversity.
Author : C. G. N. Mascie-Taylor,Barry Bogin
Publisher : Cambridge University Press
Page : 260 pages
File Size : 52,7 Mb
Release : 1995-07-13
Category : Science
ISBN : 9780521453998
Plasticity refers to the ability of many organisms to change their biology or behaviour to respond to changes in the environment, particularly when these are stressful. Humans are, perhaps, the most plastic of all species, and hence the most variable. This book reflects on the history of research in this area, state-of-the-art research methods and discoveries and needs for future research in human plasticity and variability. Topics discussed include child growth, starvation, disease of both young and old and the effects of migration, modernisation and other life-style changes. The book will be especially useful to biological anthropologists, human biologists and medical scientists interested in knowing more about how and why humans vary.
Author : Michael P. Muehlenbein
Publisher : Cambridge University Press
Page : 128 pages
File Size : 43,5 Mb
Release : 2010-07-29
Category : Social Science
ISBN : 9781139789004
Wide-ranging and inclusive, this text provides an invaluable review of an expansive selection of topics in human evolution, variation and adaptability for professionals and students in biological anthropology, evolutionary biology, medical sciences and psychology. The chapters are organized around four broad themes, with sections devoted to phenotypic and genetic variation within and between human populations, reproductive physiology and behavior, growth and development, and human health from evolutionary and ecological perspectives. An introductory section provides readers with the historical, theoretical and methodological foundations needed to understand the more complex ideas presented later. Two hundred discussion questions provide starting points for class debate and assignments to test student understanding.
Author : Herman E. Wyandt,Golder N. Wilson,Vijay S. Tonk
Publisher : Springer
Page : 490 pages
File Size : 54,8 Mb
Release : 2017-03-28
Category : Medical
ISBN : 9789811030352
This new edition now titled “Human Chromosome Variation: Heteromorphism, Polymorphism and Pathogenesis” provides the reader with an up-to-date overview of microarrays, fragile sites, copy number variations and whole genome sequencing. Greatly expanding the discussion of microarray analysis in the previous edition of the book, are new chapters on microarray and genomic analysis, plus comprehensive tables on the subtle microdeletions and microduplications that are found on each chromosome, including 235 recurring copy number variants that are associated with well-established or emerging chromosomal syndromes. The current edition features concise information on cytogenetic methods and applications, extending these discussions to DNA analysis and genome sequencing. Sections on euchromatin, heterochromatin, FISH pattern, fragile site, copy number, and DNA sequence variation are integrated with actual clinical examples from cytogenetic laboratories and from clinical practice. The principles that allow for the distinction between benign chromosome / DNA variation and pathogenic heteromorphisms / polymorphisms are discussed and include references to the latest organizational guidelines and genomic or population databases. The two previous incarnations of this book: the ‘Atlas of Human Chromosome Heteromorphism’, and ‘Human Chromosome Variation: Heteromorphism and Polymorphism’ have been standard reference works in most cytogenetic laboratories, used by laboratory directors and clinicians all around the world. While widely used sections from the previous edition on cytogenetic technologies and heteromorphisms are retained intact the present volume adds extensive material on copy number variations (polymorphisms detected by microarray analysis), fragile sites in disease and cancer, and practical views on interpreting emerging technologies, including whole exome sequencing. This book should be of interest to clinicians, technicians and students who are or will be exposed to DNA and/or chromosome analysis and the data derived from these continuously developing techniques. This fully updated book volume will bring the reader up to speed on the latest technologies, their applications, benefits and drawbacks and as such, is a must read for anyone with an interest in DNA and chromosome analysis and the distinction between benign variation and pathogenic mistakes.
Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Applications of Toxicogenomic Technologies to Predictive Toxicology
Publisher : National Academies Press
Page : 300 pages
File Size : 45,9 Mb
Release : 2007-11-19
Category : Science
ISBN : 9780309178891
The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new waysâ€"an effort requiring funding, interagency coordination, and data management strategies.
Author : Ronald A. Bergman,Sue Ann Thompson,Adel K. Afifi
Publisher : Unknown
Page : 258 pages
File Size : 52,5 Mb
Release : 1984
Category : Science
ISBN : UOM:39015023231981