Immunobiology Of Hla

Author : Bo Dupont
Publisher : Springer
Page : 636 pages
File Size : 42,7 Mb
Release : 2013-12-20
Category : Medical
ISBN : 9783662399460

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Immunobiology of HLA by Bo Dupont Pdf

This set reports the results of the 10th International Histocompatibility Workshop, in which 362 laboratories collaborated over a three year period in research projects on the classification of HLA genes and their products. Volume 1 describes the experimental design of the workshop studies and their results. Volume 2 is a collection of papers on the latest developments in the molecular biology of HLA systems. Immunobiology of HLA is a valuable reference for tissue typing laboratories, blood banks, and general research programs on HLA and related diseases because it identifies common sources of HLA genes and gene products to be used as reference reagents, and because it is the only complete compilation of the latest research and results in the field.

Author : Bo Dupont
Publisher : Springer Science & Business Media
Page : 1116 pages
File Size : 41,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461235521

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Immunobiology of HLA by Bo Dupont Pdf

The Tenth International Histocompatibility Workshop of this work, and Fran Berman for her help in preparing component concerning T-cell recognition of HLA class the report. MaryAnn Barletta, Sally Krell, and Halina II molecules drew its strength from the hard work, Korsun provided invaluable help with a multitude of diligence, and selfless spirit of the 23 participating organizational and operational issues. Bo Dupont and laboratories. The enthusiasm and camaraderie exhib Bob Knowles provided sound advice, helpful discus ited by the participants in Princeton during November sions, and continued support. John Hansen, Jean Marc 1987 bear testimony to the caliber of the individuals Lalouel, and the other members ofthe Organizing Com involved. mittee made valuable contributions. Rosemarie Pliitke's Numerous individuals, both inside and outside of the enthusiasm, diligence, and statistical expertise were Organizing Committee, contributed significantly to the vital ingredients in this undertaking. John Klein was success of this component of the Workshop. We thank always ready to step in and assume whatever responsibil David Eckels, Adrianna Zeevi, Nancy Reinsmoen, and ity was necessary to keep the work going. Above all, I Eric Mickelson for their continued advice, encourage owe special and personal thanks to my family, whose ment, and hard work throughout this endeavor. We thank patience, support, and understanding helped to sustain Deborah Richardson for her help during the early stages me over the last 2 years."

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 45,8 Mb
Release : 1989
Category : HLA histocompatibility antigens
ISBN : LCCN:88039761

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Immunobiology of HLA: Immunogenetics and histocompatibility by Anonim Pdf

Author : Bo Dupont
Publisher : Springer My Copy UK
Page : 1146 pages
File Size : 44,9 Mb
Release : 1989
Category : HLA histocompatibility antigens
ISBN : 1461235537

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IMMUNOBIOLOGY OF HLA by Bo Dupont Pdf

This set reports the results of the 10th International Histocompatibility Workshop, in which 362 laboratories collaborated over a three year period in research projects on the classification of HLA genes and their products. "Volume 1" describes the experimental design of the workshop studies and their results. "Volume 2" is a collection of papers on the latest developments in the molecular biology of HLA systems. Immunobiology of HLA is a valuable reference for tissue typing laboratories, blood banks, and general research programs on HLA and related diseases because it identifies common sources of HLA genes and gene products to be used as reference reagents, and because it is the only complete compilation of the latest research and results in the field.

Author : Narinder K Mehra
Publisher : Boydell & Brewer Ltd
Page : 616 pages
File Size : 47,5 Mb
Release : 2010-11-26
Category : Medical
ISBN : 818448870X

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The HLA Complex in Biology and Medicine by Narinder K Mehra Pdf

A comprehensive guide to the HLA (Human Leukocyte Antigen) system for immunologists and clinicians, this book contains up-to-date information on the MHC (Major Histocompatibility Complex) and its role in the immune response and in various diseases. The book explores the biological significance and role of the HLA system in organ and haematopoietic stem cell transplantation management. This volume is an invaluable guide to the full spectrum of HLA-related science while also serving as a conceptual and technical resource for those involved in HLA-related research and in clinical or surgical practice. In addition, it will be a primary point of contact for individuals working in other areas who suddenly find that their research is drawing them into the complexities of HLA genetics.

Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 46,9 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570

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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Author : Robert Lechler,Anthony Warrens
Publisher : Academic Press
Page : 506 pages
File Size : 54,9 Mb
Release : 2000-05-09
Category : Medical
ISBN : UOM:39015042405707

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HLA in Health and Disease by Robert Lechler,Anthony Warrens Pdf

This comprehensive and definitive work succeeds and expands on the highly successful HLA and Disease published in 1994. This new edition has been updated, redesigned and reorganised into three sections making it an invaluable reference. The introductory section summarises current knowledge on the structure, function, genetics and evolution of the HLA system. It clarifies its complex and ever changing nomenclature and discusses the mechanisms underlying disease associations with HLA alleles. The second section deals with the importance of HLA in the context of different clinical specialities. Individual chapters describe the association between HLA polymorphism and each disease. The final section features chapters on current laboratory practice in histocompatibility and tissue typing. HLA in Health and Disease is essential reading for basic and clinical researchers working in immunology and immunogenetics, transplantation medicine and autoimmunity. It will also be of interest to anyone in the fields of rheumatology, diabetology, nephrology, allergy, dermatology, neurology, endocrinology, cancer biology, respiratory medicine, haematology, molecular biology and biochemistry. Key Features Structure, function and genetics of HLA HLA nomenclature Evolution of HLA polymorphisms HLA associations in arthritis and rheumatology, renal disease, neurology, diabetes and endocrinology, gastroenterology, respiratory disease, ophthalmology, infections, dermatology and psychiatry HLA and organ transplantation Serological and PCR-based methods in HLA typing Cellular techniques in testing histocompatibility Edited and written by an international panel of experts in the field

Author : René R. P. de Vries,Jon J. van Rood
Publisher : S Karger Ag
Page : 0 pages
File Size : 44,5 Mb
Release : 1985
Category : Medical
ISBN : 3805538936

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Immunobiology of HLA Class-I and Class-II Molecules by René R. P. de Vries,Jon J. van Rood Pdf

Author : Antonella Mancusi,Antonio Pierini,Christopher G. Kanakry
Publisher : Frontiers Media SA
Page : 153 pages
File Size : 40,8 Mb
Release : 2020-07-03
Category : Electronic
ISBN : 9782889638246

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The Immunobiology of HLA-Haploidentical Hematopoietic Cell Transplantation by Antonella Mancusi,Antonio Pierini,Christopher G. Kanakry Pdf

Author : Batool Mutar Mahdi
Publisher : BoD – Books on Demand
Page : 70 pages
File Size : 50,9 Mb
Release : 2019-03-13
Category : Medical
ISBN : 9781789857610

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Human Leukocyte Antigen (HLA) by Batool Mutar Mahdi Pdf

This book is a concise review of medically important applications of Human Leukocyte Antigen (HLA) in medicine. It covers both basic knowledge of HLA and its main clinical applications in medical practice. Its two major aims are to assist students who are preparing for clinical immunology examinations, and to help people who want to understand more about this subject with brief and flexible sources of information. This book presents current, medically important information on the rapidly changing field of tissue typing and its relation with diseases. It includes updated information on such topics as tissue typing in medicine and transplant immunology.

Author : Fritz H. Bach,Robert A. Good
Publisher : Academic Press
Page : 222 pages
File Size : 49,6 Mb
Release : 2016-02-25
Category : Health & Fitness
ISBN : 9781483216355

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Clinical Immunobiology by Fritz H. Bach,Robert A. Good Pdf

Clinical Immunobiology, Volume 4 is a 13-chapter text that covers the advances in understanding of the concepts and practical applications of lymphoid subpopulations and the major histocompatibility complex (MHC). The first chapter presents an overview of the problems of various subpopulations of cells involved in the immune system. The succeeding chapters describe the techniques used for cell classification, either by their cell surface phenotype or by their responsiveness to a series of different stimuli. These chapters include surveys of the methods of detection of complement receptors and expression of these receptors on the surface of both normal and leukemic human lymphocytes. A discussion of the evidence that different T-lymphocyte populations differentially express receptor for IgG and IgM is also provided. Other chapters describe the relationship of MHC to serology of cell surface antigens and reactivity in the mixed leukocyte culture test. This work also explores the methods that employ the so-called "proliferative and cytotoxic responses". The remaining chapters look into the association between HLA antigens and a variety of different diseases. These chapters also discuss other genetic markers in the HLA linkage group. This book will be of great value to clinical immunobiologists, practicing physicians, researchers, and medical and biology students.

Author : John Lee
Publisher : Springer Science & Business Media
Page : 236 pages
File Size : 42,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461234548

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The HLA System by John Lee Pdf

This volume documents our growing understanding of the human major histocompatibility complex. The application of this information is ever more important as the limits of transplantation continue to be reduced, including the recent success of bone marrow transplantation between unrelated but closely matched individuals. In addition, the need to transfuse platelets in the face of immunologic barriers continues to challenge transfusion services. Thus, the serologic information summarized in this volume is essential for optimal patient care. At the same time, recombinant DNA technology has led to a revolution in our understanding of many aspects of basic biology. Among the advances has been the initial characterization of the structure of some HLA loci. While this will ultimately improve clinical services, constant reference to serologic data is essential so that the powerful new techniques can be applied in the most effective ways. The timing of the First Red Cross International Histocompatibility Workshop is fortunate as it brings together experts from around the world to address the state of the art. We are all grateful to Dr. John Lee and his colleagues for organizing the workshop, and for bringing together in this volume the material to be presented in Beijing during October 17-23, 1990. Leon W. Hoyer, M.D.

Author : Philip Hornick
Publisher : Springer Science & Business Media
Page : 430 pages
File Size : 53,6 Mb
Release : 2008-02-05
Category : Medical
ISBN : 9781597450492

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Transplantation Immunology by Philip Hornick Pdf

Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection.

Author : Julius Cruse,Robert Lewis,Huan Wang
Publisher : Elsevier
Page : 1000 pages
File Size : 51,8 Mb
Release : 2004-08-05
Category : Medical
ISBN : 9780080478425

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Immunology Guidebook by Julius Cruse,Robert Lewis,Huan Wang Pdf

The Immunology Guidebook provides an easily accessible text-reference to the more up-to-date and difficult concepts in the complex science of immunology. It aims to demystify basic concepts and specialised molecular and cellular interactions. Its 18 chapters offer a logical and sequential presentation where much of the data is displayed in carefully designed tables. This book is intended for immunology students, researchers, practitioners and basic biomedical scientists. Tables provide a quick reference to ‘difficult to find' immunology data A distillate of the latest information on immunogenetics of the human MHC associated with tissue transplantation Information boxes featurw related web resources

Author : J.L. Tiwari,P.I. Terasaki
Publisher : Springer Science & Business Media
Page : 492 pages
File Size : 55,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461385455

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HLA and Disease Associations by J.L. Tiwari,P.I. Terasaki Pdf

The human leukocyte antigen (HLA) or tissue types are the products of a rapidly developing field of knowledge within the last 20 years. In the early stages of the research many investigators suspected the existence of a complex series of transplantation antigens, but it was widely believed that these antigens would not be well-defined even in this century. Yet in the last two decades as many as 124 different HLA antigens determined by at least 7 very closely linked genes located on the short arm of chromosome 6 have been identified and subsequently agreed upon by an international nomenclature committee. 1 Extensive international collaboration fueled by the potential clinical application of these antigens to clinical transplantation has advanced the field rapidly. There were nine inter national histocompatibility workshops held during this period. Although iden tification of HLA antigens was of primary clinical importance in transplantation 2 and of great basic interest in human genetics and anthropology, a rather un expected bonus has been the determination that HLA antigens are associated with disease susceptibility to a greater extent than any other known genetic marker in man. In the past, many genetic polymorphisms have been suspected to be associated with diseases. The most extensively studied markers are blood groups, enzymes, and serum proteins. A comprehensive account of published studies, totalling approximately 1,000, of these markers is available in a book by Mourant et al.