Innovative Dosage Forms

Author : Yogeshwar Bachhav
Publisher : John Wiley & Sons
Page : 470 pages
File Size : 54,5 Mb
Release : 2019-12-04
Category : Science
ISBN : 9783527343966

Get Book

Innovative Dosage Forms by Yogeshwar Bachhav Pdf

Teaches future and current drug developers the latest innovations in drug formulation design and optimization This highly accessible, practice-oriented book examines current approaches in the development of drug formulations for preclinical and clinical studies, including the use of functional excipients to enhance solubility and stability. It covers oral, intravenous, topical, and parenteral administration routes. The book also discusses safety aspects of drugs and excipients, as well as regulatory issues relevant to formulation. Innovative Dosage Forms: Design and Development at Early Stage starts with a look at the impact of the polymorphic form of drugs on the preformulation and formulation development. It then offers readers reliable strategies for the formulation development of poorly soluble drugs. The book also studies the role of reactive impurities from the excipients on the formulation shelf life; preclinical formulation assessment of new chemical entities; and regulatory aspects for formulation design. Other chapters cover innovative formulations for special indications, including oncology injectables, delayed release and depot formulations; accessing pharmacokinetics of various dosage forms; physical characterization techniques to assess amorphous nature; novel formulations for protein oral dosage; and more. -Provides information that is essential for the drug development effort -Presents the latest advances in the field and describes in detail innovative formulations, such as nanosuspensions, micelles, and cocrystals -Describes current approaches in early pre-formulation to achieve the best in vivo results -Addresses regulatory and safety aspects, which are key considerations for pharmaceutical companies -Includes case studies from recent drug development programs to illustrate the practical challenges of preformulation design Innovative Dosage Forms: Design and Development at Early Stage provides valuable benefits to interdisciplinary drug discovery teams working in industry and academia and will appeal to medicinal chemists, pharmaceutical chemists, and pharmacologists.

Author : Usama Ahmad
Publisher : Unknown
Page : 0 pages
File Size : 48,7 Mb
Release : 2023
Category : Drugs
ISBN : 1803552115

Get Book

Dosage Forms by Usama Ahmad Pdf

Author : Ram I. Mahato,Ajit S. Narang
Publisher : CRC Press
Page : 690 pages
File Size : 53,8 Mb
Release : 2017-11-22
Category : Medical
ISBN : 9781482253672

Get Book

Pharmaceutical Dosage Forms and Drug Delivery by Ram I. Mahato,Ajit S. Narang Pdf

Completely revised and updated, this third edition of Pharmaceutical Dosage Forms and Drug Delivery elucidates the basic principles of pharmaceutics, biopharmaceutics, dosage form design, and drug delivery – including emerging new biotechnology-based treatment modalities. The authors integrate aspects of physical pharmacy, chemistry, biology, and biopharmaceutics into drug delivery. This book highlights the increased attention that the recent spectacular advances in gene therapy and nanotechnology have brought to dosage form design and drug delivery. With the expiration of older patents and generic competition, the biopharmaceutical industry is evolving faster than ever. Apart from revising and updating existing chapters on the basic principles, this edition highlights the emerging emphasis on drug discovery, antibodies and antibody-drug conjugates as therapeutic moieties, individualized medicine including patient stratification strategies, targeted drug delivery, and the increasing role of modeling and simulation. Although there are numerous books on pharmaceutics and dosage forms, most cover different areas of the discipline and do not provide an integrated approach. The integrated approach of this book not only provides a singular perspective of the overall field, but also supplies a unified source of information for students, instructors and professionals, saving their time and money.

Author : Nina Dragićević
Publisher : CRC Press
Page : 212 pages
File Size : 51,6 Mb
Release : 2021
Category : Medical
ISBN : 1003187331

Get Book

Invasomes As Drug Nanocarriers for Innovative Pharmaceutical Dosage Forms by Nina Dragićević Pdf

"This book details the novel nanocarriers named 'invasomes" and how they are used for dermal and transdermal drug delivery. The text describes their composition, usage of skin as a drug delivery route and liposomes as skin delivery systems. Included are reviewed studies revealing the importance of invasomes in this field"--

Author : Larry L. Augsburger,Stephen W. Hoag
Publisher : CRC Press
Page : 436 pages
File Size : 42,7 Mb
Release : 2017-10-30
Category : Medical
ISBN : 9781841849775

Get Book

Pharmaceutical Dosage Forms by Larry L. Augsburger,Stephen W. Hoag Pdf

Pharmaceutical Dosage Forms: Capsules covers the development, composition, and manufacture of capsules. Despite the important role that capsules play in drug delivery and product development, few comprehensive texts on the science and technology of capsules have been available for the research and academic environments. This text addresses this gap, discussing how capsules provide unique capabilities and options for dosage form design and formulation.

Author : Howard C. Ansel
Publisher : Unknown
Page : 424 pages
File Size : 42,5 Mb
Release : 1985
Category : Medical
ISBN : UOM:39015009580716

Get Book

Introduction to Pharmaceutical Dosage Forms by Howard C. Ansel Pdf

Author : Larry L. Augsburger,Stephen W. Hoag
Publisher : CRC Press
Page : 1558 pages
File Size : 55,8 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781420063868

Get Book

Pharmaceutical Dosage Forms - Tablets by Larry L. Augsburger,Stephen W. Hoag Pdf

The ultimate goal of drug product development is to design a system that maximizes the therapeutic potential of the drug substance and facilitates its access to patients. Pharmaceutical Dosage Forms: Tablets, Third Edition is a comprehensive resource of the design, formulation, manufacture, and evaluation of the tablet dosage form, an

Author : Anonim
Publisher : Academic Press
Page : 810 pages
File Size : 40,6 Mb
Release : 2018-07-25
Category : Medical
ISBN : 9780128144220

Get Book

Dosage Form Design Parameters by Anonim Pdf

Dosage Form Design Parameters, Volume II, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries. Examines the history and recent developments in drug dosage forms for pharmaceutical sciences Focuses on physicochemical aspects, prefomulation solid state properties and polymorphism Contains extensive references for further discovery and learning that are appropriate for advanced undergraduates, graduate students and those interested in drug dosage design

Author : Ambikanandan Misra,Aliasgar Shahiwala
Publisher : Springer Nature
Page : 448 pages
File Size : 43,7 Mb
Release : 2020-02-12
Category : Medical
ISBN : 9789811336423

Get Book

Novel Drug Delivery Technologies by Ambikanandan Misra,Aliasgar Shahiwala Pdf

The application of drug delivery is a valuable, cost-effective lifecycle management resource. By endowing drugs with new and innovative therapeutic benefits, drug delivery systems extend products’ profitable lifecycle, giving pharmaceutical companies competitive and financial advantages, and providing patients with improved medications. Formulation development is now being used to create new dosage forms for existing products, which not only reduces the time and expense involved in new drug development, but also helps with regard to patent protection and bypassing existing patents. Today’s culture demands convenience, a major factor determining adherence to drug therapy. Over the past few years, patient convenience-oriented research in the field of drug delivery has yielded a range of innovative drug-delivery options. As a result, various drug-delivery systems, including medicated chewing gums, oral dispersible tablets, medicated lozenges and lollipops, have now hit the market and are very popular. These dosage forms offer a highly convenient way to dose medications, not only for special population groups with swallowing difficulties, such as children and the elderly, but for the general populace as well. This book provides valuable insights into a number of formulation design approaches that are currently being used, or could be used, to provide new benefits from existing drug molecules.

Author : Loyd V. Allen,Timothy B. McPherson
Publisher : Lippincott Williams & Wilkins
Page : 1629 pages
File Size : 40,8 Mb
Release : 2021-08-16
Category : Medical
ISBN : 9781975171780

Get Book

Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems by Loyd V. Allen,Timothy B. McPherson Pdf

The most trusted source on the subject available today, Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, 12th Edition equips pharmacy students with everything they need to master the intricacies of pharmaceutical dosage form design and production and achieve successful outcomes in their courses and beyond. Reflecting the latest CAPE, APhA, and NAPLEX® competencies, this trusted, extensively updated resource clarifies the interrelationships between pharmaceutical and biopharmaceutical principles, product design, formulation, manufacture, compounding, and the clinical application of the various dosage forms in patient care, as well as regulations and standards governing the manufacturing and compounding of pharmaceuticals. New and revised content throughout keeps students up to date with current approaches to key coverage areas, and additional case studies demonstrate concepts in action to reinforce understanding and prepare students for the clinical challenges ahead.

Author : Yogeshwar Bachhav
Publisher : John Wiley & Sons
Page : 352 pages
File Size : 43,9 Mb
Release : 2019-08-09
Category : Science
ISBN : 9783527812202

Get Book

Innovative Dosage Forms by Yogeshwar Bachhav Pdf

Teaches future and current drug developers the latest innovations in drug formulation design and optimization This highly accessible, practice-oriented book examines current approaches in the development of drug formulations for preclinical and clinical studies, including the use of functional excipients to enhance solubility and stability. It covers oral, intravenous, topical, and parenteral administration routes. The book also discusses safety aspects of drugs and excipients, as well as regulatory issues relevant to formulation. Innovative Dosage Forms: Design and Development at Early Stage starts with a look at the impact of the polymorphic form of drugs on the preformulation and formulation development. It then offers readers reliable strategies for the formulation development of poorly soluble drugs. The book also studies the role of reactive impurities from the excipients on the formulation shelf life; preclinical formulation assessment of new chemical entities; and regulatory aspects for formulation design. Other chapters cover innovative formulations for special indications, including oncology injectables, delayed release and depot formulations; accessing pharmacokinetics of various dosage forms; physical characterization techniques to assess amorphous nature; novel formulations for protein oral dosage; and more. -Provides information that is essential for the drug development effort -Presents the latest advances in the field and describes in detail innovative formulations, such as nanosuspensions, micelles, and cocrystals -Describes current approaches in early pre-formulation to achieve the best in vivo results -Addresses regulatory and safety aspects, which are key considerations for pharmaceutical companies -Includes case studies from recent drug development programs to illustrate the practical challenges of preformulation design Innovative Dosage Forms: Design and Development at Early Stage provides valuable benefits to interdisciplinary drug discovery teams working in industry and academia and will appeal to medicinal chemists, pharmaceutical chemists, and pharmacologists.

Author : Nina Dragicevic
Publisher : Unknown
Page : 128 pages
File Size : 53,5 Mb
Release : 2021
Category : Drug delivery systems
ISBN : 1032034513

Get Book

Invasomes as Drug Nanocarriers for Innovative Pharmaceutical Dosage Forms by Nina Dragicevic Pdf

"This book details the novel nanocarriers named 'invasomes" and how they are used for dermal and transdermal drug delivery. The text describes their composition, usage of skin as a drug delivery route and liposomes as skin delivery systems. Included are reviewed studies revealing the importance of invasomes in this field"--

Author : Nina Dragićević
Publisher : CRC Press
Page : 222 pages
File Size : 53,6 Mb
Release : 2021-10-12
Category : Medical
ISBN : 9781000483550

Get Book

Invasomes as Drug Nanocarriers for Innovative Pharmaceutical Dosage Forms by Nina Dragićević Pdf

This book details the novel nanocarriers named 'invasomes" and how they are used for dermal and transdermal drug delivery. The text describes their composition, usage of skin as a drug delivery route and liposomes as skin delivery systems. Included are reviewed studies revealing the importance of invasomes in this field.

Author : Anonim
Publisher : Academic Press
Page : 820 pages
File Size : 51,6 Mb
Release : 2018-07-28
Category : Medical
ISBN : 9780128144244

Get Book

Dosage Form Design Considerations by Anonim Pdf

Dosage Form Design Parameters, Volume I, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries. Examines the history and recent developments in drug dosage forms for pharmaceutical sciences Focuses on physicochemical aspects, prefomulation solid state properties and polymorphism Contains extensive references for further discovery and learning that are appropriate for advanced undergraduates, graduate students and those interested in drug dosage design

Author : Bhavishya Mittal
Publisher : Academic Press
Page : 190 pages
File Size : 55,9 Mb
Release : 2016-10-05
Category : Medical
ISBN : 9780128047323

Get Book

How to Develop Robust Solid Oral Dosage Forms by Bhavishya Mittal Pdf

How to Develop Robust Solid Oral Dosage Forms from Conception to Post-Approval uses a practical and hands-on approach to cover the development process of solid oral dosage forms in one single source. The book details all of the necessary steps from formulation through the post-approval phase and contains industry case studies, real world advice, and troubleshooting tips. By merging the latest scientific information with practical instructions, this book provides pharmaceutical scientists in formulation research and development with a concrete look at the key aspects in the development of solid oral dosage forms. Focuses on important topics, such as robustness, bioavailability, formulation design, continuous processing, stability tests, modified release dosage forms, international guidelines, process scale-up, and much more Part of the Expertise in Pharmaceutical Process Technology series edited by Michael Levin Discusses common, real-world problems and offers both theoretical and practical solutions to these everyday issues