Inorganic Biochemistry Of Iron Metabolism

Author : Robert R. Crichton,Johan R. Boelaert
Publisher : John Wiley & Sons
Page : 370 pages
File Size : 47,6 Mb
Release : 2001-10-17
Category : Medical
ISBN : 047149223X

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Inorganic Biochemistry of Iron Metabolism by Robert R. Crichton,Johan R. Boelaert Pdf

Iron is of fundamental importance for the growth, development and well being of almost all living organisms. Multiple biological systems have been developed for the uptake, utilisation, storage and homeostasis of iron in microbes, plants and mammals. e.g. Both iron deficiency and iron overload are found extensively in man: the intimate links between iron and oxidative stress are associated with a wide range of pathologies; iron has a well established role in infections by a wide range of microorganisms and parasites; there is a close link between iron requirements and cellular division with implications for cancers and other metals such as copper and zinc are closely linked with iron metabolism. The first edition of this book was published in 1991. Since then the extensive impact of molecular cell biology on the field of iron biochemistry has opened new horizons in our understanding of the transport and storage of iron and of its homeostasis. The explosive use of molecular biological techniques applied to cellular biology of iron metabolism has resulted in a rapid expansion in the literature which has led to the need for this second edition. This second edition also: Introduces many illustrations and colour photos to make the basic concepts far clearer Includes new chapters on iron and cell division and interactions of iron with other metals - particularly copper and zinc Provides additional anecdotes Incorporates an extensive and up-to-date bibliography

Author : Robert R. Crichton
Publisher : Ellis Horwood
Page : 272 pages
File Size : 53,8 Mb
Release : 1991
Category : Medical
ISBN : UOM:39015024950100

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Inorganic Biochemistry of Iron Metabolism by Robert R. Crichton Pdf

Concentrates on the importance of iron in biology, emphasizing the need for well-defined amounts of iron for the survival, replication and differentiation of the cells of animals, plants and almost all micro-organisms.

Author : Glória C. Ferreira,José João G. Moura,Ricardo Franco
Publisher : John Wiley & Sons
Page : 410 pages
File Size : 41,6 Mb
Release : 2008-09-26
Category : Science
ISBN : 9783527613717

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Iron Metabolism by Glória C. Ferreira,José João G. Moura,Ricardo Franco Pdf

Iron plays a crucial role in many biochemical processes. In recent years intensive research has led to a better understanding of the function of iron in cellular metabolism. In more than twenty articles internationally renowned experts give a thorough account of the recent developments of this fascinating field. The book focuses on the central questions, e.g. transport, storage, and utilization of iron in cells, the three-dimensional structure of iron-containing proteins, the physiological function of heme and iron sulfur-containing proteins, and the regulatory mechanisms in heme biosynthesis and redox regulation of signal transduction. The interdisciplinary character of the book is designed to explore the many facets of the new findings and to provide a comprehensive overview of recent advances for biochemists, bioinorganic chemists, molecular biologists, microbiologists and immunologists. The reviews are supplemented with valuable background information, results and numerous references. This book emphasizes the relationships between the different disciplines concerned with iron metabolism and opens new perspectives for future research!

Author : Robert Crichton
Publisher : Unknown
Page : 355 pages
File Size : 44,5 Mb
Release : 2003
Category : Electronic
ISBN : OCLC:1027205179

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Inorganic Biochemistry of Iron Metabolism by Robert Crichton Pdf

Iron is of fundamental importance for the growth, development and well being of almost all living organisms. Multiple biological systems have been developed for the uptake, utilisation, storage and homeostasis of iron in microbes, plants and mammals. e.g. Both iron deficiency and iron overload are found extensively in man: the intimate links between iron and oxidative stress are associated with a wide range of pathologies; iron has a well established role in infections by a wide range of microorganisms and parasites; there is a close link between iron requirements and cellular division with im.

Author : Prem Ponka,Herbert M. Schulman,Robert C. Woodworth,Goetz W. Richter
Publisher : CRC Press
Page : 360 pages
File Size : 52,5 Mb
Release : 1990-09-25
Category : Medical
ISBN : 0849366771

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Iron Transport and Storage by Prem Ponka,Herbert M. Schulman,Robert C. Woodworth,Goetz W. Richter Pdf

The objective of this book is to review and summarize recent developments in our understanding of iron transport and storage in living systems. It includes an overview of the evolutionary aspects of iron metabolism and bacterial iron transport, as well as a detailed discussion of molecules with specific roles in iron metabolism in higher organisms. It also presents relationships between intracellular iron metabolism and cell proliferation. Iron Transport and Storage addresses the comparative aspects of iron transport and storage in different tissues. This essential volume is very useful for hematologists, physical and biological chemists, cell and molecular biologists, physiologists, and clinicians with an interest in the biology and metabolism of iron.

Author : Robert Crichton
Publisher : John Wiley & Sons
Page : 581 pages
File Size : 48,5 Mb
Release : 2016-05-31
Category : Medical
ISBN : 9781118925614

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Iron Metabolism by Robert Crichton Pdf

Iron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems a natural target for pathogenic microorganisms and parasites. Uniquely, humans suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is associated with a wide range of human pathologies, including many neurodegenerative diseases. Whereas some essential metal ions like copper and zinc are closely linked with iron metabolism, toxic metals like aluminium and cadmium can interfere with iron metabolism. Finally, iron metabolism and homeostasis are key targets for the development of new drugs for human health. The 4th edition of Iron Metabolism is written in a lively style by one of the leaders in the field, presented in colour and covers the latest discoveries in this exciting area. It will be essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and medical sciences. Other interested groups include biological inorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, or of diseases in which iron uptake systems are involved (eg. microbial and fungal infections, cancer, neurodegenerative disorders), and researchers in the pharmaceutical industry interested in developing novel drugs targeting iron metabolism/homeostasis.

Author : Anatoly Bezkorovainy
Publisher : Springer Science & Business Media
Page : 445 pages
File Size : 52,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468437799

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Biochemistry of Nonheme Iron by Anatoly Bezkorovainy Pdf

Atomic biology has come of age. Interest in the role of chemical elements in life processes has captured the imagination of a wide spectrum of research scientists-ranging from the nutritionist to the biochemist, the inorganic chemist, and even to some biophysicists. This series, Biochemistry of the Elements, is a recognition of this increasing interest. When complete, the books will assemble the hard facts concerning the biochemistry of each element-singly or in a logical grouping. The series will provide a permanent reference for this active and growing field. Each volume shall represent an integrated effort by one or several authors to describe the current knowledge of an element(s) or the methods by which it is studied. Iron is the only element to which we have devoted two volumes, because its biological and chemical role is so versatile and complex. These two volumes will treat the two main structural categories of iron: heme and nonheme iron. In this volume on nonheme iron, the first in the series, Anatoly Bezkorovainy provides what we believe is the most comprehensive treatment of this important topic.

Author : B.H. Dunford,D. Dolphin,K.N. Raymond,L. Sieker
Publisher : Springer
Page : 415 pages
File Size : 52,9 Mb
Release : 1982-07-31
Category : Science
ISBN : 9027714444

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The Biological Chemistry of Iron by B.H. Dunford,D. Dolphin,K.N. Raymond,L. Sieker Pdf

The results of a NATO Advanced Study Institute (ASI) entitled "Coordination Chemistry Environments in Iron-Containing Proteins and Enzymes - Including Smaller Molecules and Model Systems" are summarized in this book. The ASI was held in the Province of Alberta, Canada, from August 23 to September 4, 1981. The first half of the conference was held on the campus of the University of Alberta, Edmonton, and the second half at the Overlander Lodge, Hinton. Two other conferences had the greatest impact upon the planning for this ASI. One was a NATO ASI held in Tomar, Portugal in September of 1979, entitled "Metal Ions in Biology". Among the organizers for that conference were Allen Hill and Antonio Xavier; we are happy to acknowledge their beneficial influence on our subsequent conference. The other most influential conference was one organized by Ralph Wilkins and Dennis Darnell entitled "Methods for Determining Metal Ion Environments in Proteins" which was held in Las Cruces, New Mexico, U.S.A., January 10-12, 1979. The Las Cruces conference invited lectures were published as Volume 2 of "Advances in Inorganic Biochemistry", G. Eichhorn and L. Marzilli, editors.

Author : B.H. Dunford,D. Dolphin,K.N. Raymond,L. Sieker
Publisher : Springer Science & Business Media
Page : 511 pages
File Size : 54,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400978829

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The Biological Chemistry of Iron by B.H. Dunford,D. Dolphin,K.N. Raymond,L. Sieker Pdf

The results of a NATO Advanced Study Institute (ASI) entitled "Coordination Chemistry Environments in Iron-Containing Proteins and Enzymes - Including Smaller Molecules and Model Systems" are summarized in this book. The ASI was held in the Province of Alberta, Canada, from August 23 to September 4, 1981. The first half of the conference was held on the campus of the University of Alberta, Edmonton, and the second half at the Overlander Lodge, Hinton. Two other conferences had the greatest impact upon the planning for this ASI. One was a NATO ASI held in Tomar, Portugal in September of 1979, entitled "Metal Ions in Biology". Among the organizers for that conference were Allen Hill and Antonio Xavier; we are happy to acknowledge their beneficial influence on our subsequent conference. The other most influential conference was one organized by Ralph Wilkins and Dennis Darnell entitled "Methods for Determining Metal Ion Environments in Proteins" which was held in Las Cruces, New Mexico, U.S.A., January 10-12, 1979. The Las Cruces conference invited lectures were published as Volume 2 of "Advances in Inorganic Biochemistry", G. Eichhorn and L. Marzilli, editors.

Author : Ivan Bernat
Publisher : Springer Science & Business Media
Page : 399 pages
File Size : 55,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461573081

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Iron Metabolism by Ivan Bernat Pdf

Author : Jeremy H. Brock
Publisher : Bailliere Tindall Limited
Page : 512 pages
File Size : 54,8 Mb
Release : 1994
Category : Ferritin
ISBN : UOM:39015034242746

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Iron Metabolism in Health and Disease by Jeremy H. Brock Pdf

An overview of human iron metabolism. This book reviews the metabolic importance of iron in evolution, the physiology and biochemistry of internal iron exchange, iron absorption and iron storage, the molecular regulation of cellular iron homeostasis and aspects of iron and disease.

Author : Douglas Templeton
Publisher : CRC Press
Page : 926 pages
File Size : 48,5 Mb
Release : 2002-01-23
Category : Science
ISBN : 9780824744175

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Molecular and Cellular Iron Transport by Douglas Templeton Pdf

This text analyzes the molecular mechanisms, chemical behaviour and regulation of iron transport in biological systems and offers novel methods for the assessment of iron transport across biological membranes. It details the characteristics and consequences of iron deficiency and excess to prevent diseases affecting major organ structures and promote bodily iron homeostasis.

Author : Randall B. Lauffer
Publisher : CRC Press
Page : 554 pages
File Size : 40,5 Mb
Release : 1992-08-05
Category : Medical
ISBN : 0849367794

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Iron and Human Disease by Randall B. Lauffer Pdf

Iron and Human Disease is the first book to cover the three key aspects of human iron metabolism: the accumulation of iron in adults, iron as a limiting factor for tumor and infectious cell growth, and iron as a catalyst for oxygen free radical production. The book describes the hypotheses and findings related to the role of iron in cardiovascular disease (including reperfusion injury), cancer, aging, and autoimmune and neurodegenerative diseases. Other topics covered include the molecular biology and biochemistry of iron, the general principles governing iron balance, iron in the immune system and acute phase response, and new preventive and therapeutic strategies. Iron and Human Disease will be a useful reference for biomedical investigators, physicians, nutritionists, and public health officials.

Author : Anonim
Publisher : BoD – Books on Demand
Page : 164 pages
File Size : 45,6 Mb
Release : 2022-10-05
Category : Science
ISBN : 9781839629976

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Iron Metabolism by Anonim Pdf

Iron is an essential element for numerous fundamental biologic processes. Iron-containing proteins are required for vital cellular and organismal functions including oxygen transport, mitochondrial respiration, intermediary and xenobiotic metabolism, nucleic acid replication and repair, host defense, and cell signaling. However, excess iron is toxic. This book provides a comprehensive overview of the essential role of iron in biology, the regulation of systemic and cellular iron homeostasis, and how imbalances in iron homeostasis contribute to disease.

Author : J. A. Cowan
Publisher : John Wiley & Sons
Page : 458 pages
File Size : 49,5 Mb
Release : 1997-03-21
Category : Science
ISBN : 0471188956

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Inorganic Biochemistry by J. A. Cowan Pdf

Das erfolgreiche Werk des jungen, kreativen Autors jetzt in aktualisierter und korrigierter Auflage! Der Text wurde um Fragenkomplexe und Übungsbeispiele, teils mit Lösungen, erweitert; dies empfiehlt ihn besonders zur Ergänzung einer Vorlesung.