The Biological Chemistry Of Iron

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The Biological Chemistry of Iron

Author : B.H. Dunford,D. Dolphin,K.N. Raymond,L. Sieker
Publisher : Springer Science & Business Media
Page : 542 pages
File Size : 45,8 Mb
Release : 1982-07-31
Category : Science
ISBN : 9027714444

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The Biological Chemistry of Iron by B.H. Dunford,D. Dolphin,K.N. Raymond,L. Sieker Pdf

Proceedings of the NATO Advanced Study Institute, Edmonton, Alberta, Canada, August 23-September 4, 1981

The Biological Chemistry of Iron

Author : B.H. Dunford,D. Dolphin,K.N. Raymond,L. Sieker
Publisher : Springer Science & Business Media
Page : 511 pages
File Size : 42,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400978829

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The Biological Chemistry of Iron by B.H. Dunford,D. Dolphin,K.N. Raymond,L. Sieker Pdf

The results of a NATO Advanced Study Institute (ASI) entitled "Coordination Chemistry Environments in Iron-Containing Proteins and Enzymes - Including Smaller Molecules and Model Systems" are summarized in this book. The ASI was held in the Province of Alberta, Canada, from August 23 to September 4, 1981. The first half of the conference was held on the campus of the University of Alberta, Edmonton, and the second half at the Overlander Lodge, Hinton. Two other conferences had the greatest impact upon the planning for this ASI. One was a NATO ASI held in Tomar, Portugal in September of 1979, entitled "Metal Ions in Biology". Among the organizers for that conference were Allen Hill and Antonio Xavier; we are happy to acknowledge their beneficial influence on our subsequent conference. The other most influential conference was one organized by Ralph Wilkins and Dennis Darnell entitled "Methods for Determining Metal Ion Environments in Proteins" which was held in Las Cruces, New Mexico, U.S.A., January 10-12, 1979. The Las Cruces conference invited lectures were published as Volume 2 of "Advances in Inorganic Biochemistry", G. Eichhorn and L. Marzilli, editors.

The Biological Chemistry of Iron

Author : B.H. Dunford,D. Dolphin,K.N. Raymond,L. Sieker
Publisher : Springer
Page : 415 pages
File Size : 40,5 Mb
Release : 1982-07-31
Category : Science
ISBN : 9027714444

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The Biological Chemistry of Iron by B.H. Dunford,D. Dolphin,K.N. Raymond,L. Sieker Pdf

The results of a NATO Advanced Study Institute (ASI) entitled "Coordination Chemistry Environments in Iron-Containing Proteins and Enzymes - Including Smaller Molecules and Model Systems" are summarized in this book. The ASI was held in the Province of Alberta, Canada, from August 23 to September 4, 1981. The first half of the conference was held on the campus of the University of Alberta, Edmonton, and the second half at the Overlander Lodge, Hinton. Two other conferences had the greatest impact upon the planning for this ASI. One was a NATO ASI held in Tomar, Portugal in September of 1979, entitled "Metal Ions in Biology". Among the organizers for that conference were Allen Hill and Antonio Xavier; we are happy to acknowledge their beneficial influence on our subsequent conference. The other most influential conference was one organized by Ralph Wilkins and Dennis Darnell entitled "Methods for Determining Metal Ion Environments in Proteins" which was held in Las Cruces, New Mexico, U.S.A., January 10-12, 1979. The Las Cruces conference invited lectures were published as Volume 2 of "Advances in Inorganic Biochemistry", G. Eichhorn and L. Marzilli, editors.

The Biological Chemistry of Iron

Author : B. H. Dunford,D. Dolphin,K. N. Raymond
Publisher : Unknown
Page : 536 pages
File Size : 45,6 Mb
Release : 1982-07-31
Category : Electronic
ISBN : 9400978839

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The Biological Chemistry of Iron by B. H. Dunford,D. Dolphin,K. N. Raymond Pdf

Chemistry of Iron

Author : J. Silver
Publisher : Springer Science & Business Media
Page : 316 pages
File Size : 45,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401121408

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Chemistry of Iron by J. Silver Pdf

This book is designed to be of use to the reader in two different ways. First, it is intended to provide a general introduction to all aspects of iron chemistry for readers from a variety of different scientific backgrounds. It has been written at a level suitable for use by graduates and advanced undergraduates in chemistry and biochemistry, and graduates in physics, geology, materials science, metallurgy and biology. It is not designed to be a dictionary of iron compounds but rather to provide each user with the necessary tools and background to pursue their ,individual interests in the wide areas that are influenced by the chemistry of iron. To achieve this goal each chapter has been written by a contemporary expert active in the subject so that the reader will benefit from their individual insight. Although it is generally assumed that the reader will have an understanding of bonding theories and general chemistry, the book is well referenced so that any deficiencies in the reader's background can be addressed. The book was also designed as a general reference book for initial pointers into a scientific literature that is growing steadily as the understanding and uses of this astonishingly versatile element continue to develop. To meet this aim the book attempts some coverage of all aspects of the chemistry of iron, not only outlining what understanding has been achieved to date but also identifying targets to be aimed at in the future.

Iron in Biochemistry and Medicine

Author : Allan Jacobs,M. Worwood
Publisher : Unknown
Page : 794 pages
File Size : 52,6 Mb
Release : 1974
Category : Medical
ISBN : UOM:39015004375948

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Iron in Biochemistry and Medicine by Allan Jacobs,M. Worwood Pdf

Biochemistry of Nonheme Iron

Author : Anatoly Bezkorovainy
Publisher : Springer Science & Business Media
Page : 445 pages
File Size : 40,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468437799

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Biochemistry of Nonheme Iron by Anatoly Bezkorovainy Pdf

Atomic biology has come of age. Interest in the role of chemical elements in life processes has captured the imagination of a wide spectrum of research scientists-ranging from the nutritionist to the biochemist, the inorganic chemist, and even to some biophysicists. This series, Biochemistry of the Elements, is a recognition of this increasing interest. When complete, the books will assemble the hard facts concerning the biochemistry of each element-singly or in a logical grouping. The series will provide a permanent reference for this active and growing field. Each volume shall represent an integrated effort by one or several authors to describe the current knowledge of an element(s) or the methods by which it is studied. Iron is the only element to which we have devoted two volumes, because its biological and chemical role is so versatile and complex. These two volumes will treat the two main structural categories of iron: heme and nonheme iron. In this volume on nonheme iron, the first in the series, Anatoly Bezkorovainy provides what we believe is the most comprehensive treatment of this important topic.

Inorganic Biochemistry of Iron Metabolism

Author : Robert R. Crichton,Johan R. Boelaert
Publisher : John Wiley & Sons
Page : 370 pages
File Size : 45,5 Mb
Release : 2001-10-17
Category : Medical
ISBN : 047149223X

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Inorganic Biochemistry of Iron Metabolism by Robert R. Crichton,Johan R. Boelaert Pdf

Iron is of fundamental importance for the growth, development and well being of almost all living organisms. Multiple biological systems have been developed for the uptake, utilisation, storage and homeostasis of iron in microbes, plants and mammals. e.g. Both iron deficiency and iron overload are found extensively in man: the intimate links between iron and oxidative stress are associated with a wide range of pathologies; iron has a well established role in infections by a wide range of microorganisms and parasites; there is a close link between iron requirements and cellular division with implications for cancers and other metals such as copper and zinc are closely linked with iron metabolism. The first edition of this book was published in 1991. Since then the extensive impact of molecular cell biology on the field of iron biochemistry has opened new horizons in our understanding of the transport and storage of iron and of its homeostasis. The explosive use of molecular biological techniques applied to cellular biology of iron metabolism has resulted in a rapid expansion in the literature which has led to the need for this second edition. This second edition also: Introduces many illustrations and colour photos to make the basic concepts far clearer Includes new chapters on iron and cell division and interactions of iron with other metals - particularly copper and zinc Provides additional anecdotes Incorporates an extensive and up-to-date bibliography

Iron and Human Disease

Author : Randall B. Lauffer
Publisher : CRC Press
Page : 554 pages
File Size : 44,5 Mb
Release : 1992-08-05
Category : Medical
ISBN : 0849367794

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Iron and Human Disease by Randall B. Lauffer Pdf

Iron and Human Disease is the first book to cover the three key aspects of human iron metabolism: the accumulation of iron in adults, iron as a limiting factor for tumor and infectious cell growth, and iron as a catalyst for oxygen free radical production. The book describes the hypotheses and findings related to the role of iron in cardiovascular disease (including reperfusion injury), cancer, aging, and autoimmune and neurodegenerative diseases. Other topics covered include the molecular biology and biochemistry of iron, the general principles governing iron balance, iron in the immune system and acute phase response, and new preventive and therapeutic strategies. Iron and Human Disease will be a useful reference for biomedical investigators, physicians, nutritionists, and public health officials.

Iron Metabolism

Author : Ruth Porter,David W. FitzSimons
Publisher : John Wiley & Sons
Page : 192 pages
File Size : 46,8 Mb
Release : 2009-09-16
Category : Science
ISBN : 9780470718018

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Iron Metabolism by Ruth Porter,David W. FitzSimons Pdf

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Iron Metabolism: Hepcidin

Author : Gerald Litwack
Publisher : Academic Press
Page : 280 pages
File Size : 50,9 Mb
Release : 2019-02-22
Category : Science
ISBN : 9780128178430

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Iron Metabolism: Hepcidin by Gerald Litwack Pdf

Iron Metabolism, Volume 110, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more. Focuses on the newest aspects of hormone action in connection with diseases Lays the groundwork for the focus of new chemotherapeutic targets Represents reviews on emerging areas in hormone action, cellular regulators and signaling pathways

Iron Metabolism

Author : Robert Crichton
Publisher : John Wiley & Sons
Page : 581 pages
File Size : 51,6 Mb
Release : 2016-05-31
Category : Medical
ISBN : 9781118925614

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Iron Metabolism by Robert Crichton Pdf

Iron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems a natural target for pathogenic microorganisms and parasites. Uniquely, humans suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is associated with a wide range of human pathologies, including many neurodegenerative diseases. Whereas some essential metal ions like copper and zinc are closely linked with iron metabolism, toxic metals like aluminium and cadmium can interfere with iron metabolism. Finally, iron metabolism and homeostasis are key targets for the development of new drugs for human health. The 4th edition of Iron Metabolism is written in a lively style by one of the leaders in the field, presented in colour and covers the latest discoveries in this exciting area. It will be essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and medical sciences. Other interested groups include biological inorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, or of diseases in which iron uptake systems are involved (eg. microbial and fungal infections, cancer, neurodegenerative disorders), and researchers in the pharmaceutical industry interested in developing novel drugs targeting iron metabolism/homeostasis.

Iron Metabolism

Author : Robert Crichton
Publisher : John Wiley & Sons
Page : 484 pages
File Size : 46,8 Mb
Release : 2009-02-25
Category : Medical
ISBN : 0470010290

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Iron Metabolism by Robert Crichton Pdf

Iron is of fundamental importance to the growth, development and well-being of almost all living organisms. Multiple biological systems have evolved for the uptake, utilisation, storage, and homeostasis of iron in microbes, plants and mammals. Both iron deficiency and iron overload are found extensively in humans; the intimate links between iron and oxidative stress are associated with a wide range of pathologies. Iron has a well established role in infections by a range of microorganisms and parasites. Other metals such as copper and zinc are also closely linked with iron metabolism. Iron overloads and deficiencies are important factors in the health of humans and are therefore a key target in drug development. Iron Metabolism: From Molecular Mechanisms to Clinical Consequences, 3rd Edition presents a comprehensive overview of this important field.Topics covered include: Solution chemistry of iron in biological media The importance of iron for biological systems Microbial iron transport and metabolism Iron uptake by plants and fungi Cellular iron uptake and export in mammals Intracellular iron storage and biomineralization Intracellular iron metabolism and cellular iron homeostasis Iron absorption in mammals, with particular reference to man, and regulation of systemic iron balance Pathophysiology of iron deficiency and iron overload in man Iron and oxidative stress Brain iron homeostasis and its perturbation in various neurodegenerative diseases Interactions between iron and other metals Written in a lively style by one of the leaders in the field and presented in full colour, this third, expanded edition of Iron Metabolism has been fully updated with the latest discoveries. Major additions include recent information on mitochondrial iron metabolism and the role of frataxin; transcriptional control of iron homeostasis; orally active iron chelators; the roles of hepcidin and erythropoietin; the increasing number of types of iron overload; and the importance of iron in Alzheimer’s disease. Iron Metabolism is essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and the medical sciences. It will also find space on the bookshelves of bioinorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, and pharmacologists in the pharmaceutical industry interested in developing novel iron-binding drugs.

Chemistry of Iron

Author : J. Silver
Publisher : Springer
Page : 306 pages
File Size : 44,8 Mb
Release : 1992-12-31
Category : Science
ISBN : 0751400629

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Chemistry of Iron by J. Silver Pdf

This book is designed to be of use to the reader in two different ways. First, it is intended to provide a general introduction to all aspects of iron chemistry for readers from a variety of different scientific backgrounds. It has been written at a level suitable for use by graduates and advanced undergraduates in chemistry and biochemistry, and graduates in physics, geology, materials science, metallurgy and biology. It is not designed to be a dictionary of iron compounds but rather to provide each user with the necessary tools and background to pursue their ,individual interests in the wide areas that are influenced by the chemistry of iron. To achieve this goal each chapter has been written by a contemporary expert active in the subject so that the reader will benefit from their individual insight. Although it is generally assumed that the reader will have an understanding of bonding theories and general chemistry, the book is well referenced so that any deficiencies in the reader's background can be addressed. The book was also designed as a general reference book for initial pointers into a scientific literature that is growing steadily as the understanding and uses of this astonishingly versatile element continue to develop. To meet this aim the book attempts some coverage of all aspects of the chemistry of iron, not only outlining what understanding has been achieved to date but also identifying targets to be aimed at in the future.

Iron-Containing Enzymes

Author : Samuel P de Visser,Devesh Kumar
Publisher : Royal Society of Chemistry
Page : 462 pages
File Size : 50,8 Mb
Release : 2011-08-04
Category : Science
ISBN : 9781849732987

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Iron-Containing Enzymes by Samuel P de Visser,Devesh Kumar Pdf

There are many mononuclear iron containing enzymes in nature that utilize molecular oxygen and transfer one or both oxygen atoms of O2 to substrates. These enzymes catalyze many processes including the biosynthesis of hormones, the metabolism of drugs, DNA and RNA base repair and, the biosynthesis of antibiotics. Therefore, mononuclear iron containing enzymes are important intermediates in bioprocesses and have great potential in the commercial biosynthesis of specific products since they often catalyze reactions regioselectively or stereospecifically. Understanding their mechanism and function is important and will assist in searches for commercial exploitation. In recent years, advances in experimental as well as theoretical methodologies have made it possible to study the mechanism and function of these enzymes and much information on their properties has been gained. This book highlighting recent developments in the field is, therefore, a timely addition to the literature and will interest a broad readership in the fields of biochemistry, inorganic chemistry and computational chemistry. The Editors, leaders in the field of nonheme and heme iron containing monoxygenases, have filled the book with topical review chapters by leaders in the various sub-disciplines.