Insights From Imaging In Bioinorganic Chemistry

Author : Anonim
Publisher : Academic Press
Page : 524 pages
File Size : 53,5 Mb
Release : 2016-01-11
Category : Science
ISBN : 9780128035658

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Insights from Imaging in Bioinorganic Chemistry by Anonim Pdf

Insights from Imaging in Bioinorganic Chemistry continues a long-running series that describes recent advances in scientific research, in particular, in the field of inorganic chemistry. Several highly regarded experts, mostly from academe, contribute on specific topics. The series editor chooses a sub-field within inorganic chemistry as the theme and focus of the volume, extending invitations to experts for their contributions; the current theme is insights from metal ion imaging in bioinorganic and medicinal chemistry. Contains concise, informative accounts that are not too highly specialized, therefore appealing to a wide range of scientists and health professionals Presents contributions from highly qualified international experts Provides intrinsic scientific interest and applications, including important issues relating to the diagnosis and therapeutics that are relevant to public health

Author : Astrid Sigel,Eva Freisinger,Roland K.O. Sigel
Publisher : Walter de Gruyter GmbH & Co KG
Page : 547 pages
File Size : 54,7 Mb
Release : 2021-03-08
Category : Science
ISBN : 9783110685701

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Metal Ions in Bio-Imaging Techniques by Astrid Sigel,Eva Freisinger,Roland K.O. Sigel Pdf

Volume 22, entitled Metal Ions in Bio-Imaging Techniques, of the series Metal Ions in Life Sciences deals with metal ions as tools in imaging. This dates back to the first half of the past century, when barium sulfate was orally given to patients undergoing X-ray examination. The use of contrast agents has since developed into a large interdisciplinary field encompassing not only medicine, but also chemistry, material sciences, physics, biology, engineering, and computer sciences. MILS-22 provides deep and current insights in 17 stimulating chapters on the new research frontiers of this fast growing field on bio-imaging ... and beyond. For example, adding bio-sensing yields theranostic agents, meaning diagnosis and therapy linked in the same molecule; ions of Gd, Mn, Fe, Co, Ir, 99mTc, etc., are involved. Other important topics are, e.g., metal complexes in paramagnetic Chemical Exchange Transfer (paraCEST), radiometals for Positron Emission Tomography (PET) imaging, or paramagnetic metal ion probes for 19F magnetic resonance imaging. MILS-22 is written by 57 internationally recognized experts from 12 countries, that is, from the US via Europe to China. The impact of this vibrant research area is manifested by more than 2300 references and nearly 120 figures, mostly in color, and several informative tables. To conclude, Metal Ions in Bio-Imaging Techniques is an essential resource for scientists working in the wide range from material sciences, enzymology, analytic, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that also excellent information for teaching is provided.

Author : Howard C. Hang,Matthew R. Pratt,Jennifer A. Prescher
Publisher : John Wiley & Sons
Page : 806 pages
File Size : 44,9 Mb
Release : 2023-02-06
Category : Science
ISBN : 9783527826308

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Advanced Chemical Biology by Howard C. Hang,Matthew R. Pratt,Jennifer A. Prescher Pdf

Advanced Chemical Biology The modern approach to teaching chemical biology Advanced Chemical Biology is organized around the central dogma of life, progressing from genes to proteins and higher-order cellular structures, including core application areas such as imaging, chemical genetics, activity-based protein profiling, and natural product discovery and biosynthesis. Advanced topics and applications in, e. g., microbiology, developmental biology, and neurobiology, are covered in separate sections. Every chapter is homogeneous in style and layout, consisting of a short historical introduction followed by a description of the underlying concepts and a selection of recent examples of how the concept has been turned into practice. The subdivision of the contents into core and supplemental chapters enables a flexible use in teaching, both for a one-semester and a two-semester course. Written by authors and editors coming from the leading scientific institutions that have developed the concepts and technologies for this discipline, Advanced Chemical Biology includes specific information on topics like: DNA function, synthesis and engineering, chemical approaches to genome integrity, and RNA function, synthesis, and probing Chemical approaches to transcription and RNA regulation in vivo, chemical biology of genome engineering, and peptide/protein synthesis and engineering Directed evolution for chemical biology, chemical biology of cellular metabolism, chemical biology of lipids, and protein post-translational modifications Chemical glycobiology, chemical and enzymatic modification of proteins, genetic code expansion, bio-orthogonal chemistry, and cellular imaging With its broad scope and focus on turning concepts into applications, Advanced Chemical Biology is an excellent starting point for anyone entering the field and looking for a guide to the wide range of available methods and strategies that chemical biology has to offer. With a Foreword by Nobel Laureate Carolyn Bertozzi.

Author : Michael R. Kilbourn,Peter J. H. Scott
Publisher : John Wiley & Sons
Page : 768 pages
File Size : 52,7 Mb
Release : 2021-04-12
Category : Science
ISBN : 9781119500544

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Handbook of Radiopharmaceuticals by Michael R. Kilbourn,Peter J. H. Scott Pdf

The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, 2 nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.

Author : Rudi van Eldik
Publisher : Academic Press
Page : 472 pages
File Size : 51,5 Mb
Release : 2022-03-15
Category : Science
ISBN : 9780323983037

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Advances in Inorganic Chemistry: Recent Highlights II by Rudi van Eldik Pdf

Advances in Inorganic Chemistry, Volume 79, the latest release in an esteemed series that highlights new advances in the field of inorganic chemistry, presents new and interesting topics authored by an international field of experts. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Inorganic Chemistry series

Author : Thomas J. Meade
Publisher : CRC Press
Page : 407 pages
File Size : 40,8 Mb
Release : 2022-09-27
Category : Science
ISBN : 9781000647006

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Molecular Bio-Sensors and the Role of Metal Ions by Thomas J. Meade Pdf

Volume 23, entitled Molecular Bio-Sensors and the Role of Metal Ions, of the series Metal Ions in Life Sciences (MILS) represents a milestone of contemporary progress and understanding of molecular bio-sensors for metal ions. It is bringing together the latest research in academia and industry, and it also emphasizes the spectrum of evolving regulations from regulatory bodies. This vibrant research area is covered by 31 internationally recognized experts. The impact of MILS-23 is manifested by more than 1300 references and close to 200 figures, more than 100 of them in color; further information is summarized in several tables. In conclusion, Volume 23 significantly advances our understanding of Molecular Bio-Sensors, it is therefore an essential resource for scientists working in the wide range from earth sciences, material sciences, physics, pharmacology, enzymology, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic. • It provides an understanding of the roles that metals play in living systems. • It offers an insight for the demands needed in the clinic. • It reveals the interplay between bio-sensors and therapies. The Series METAL IONS IN LIFE SCIENCES increases our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of Biological Inorganic Chemistry and coordinate the efforts of researchers in fields like biochemistry, inorganic chemistry, coordination chemistry, molecular and structural biology, enzymology, toxicology, environmental chemistry, biophysics, pharmacy, and medicine. The volumes deal with the formation, stability, structure, and reactivity of metal-containing biological compounds of low and high molecular weight. The metabolism and transport of metal ions and their complexes as well as new models of complicated natural structures and processes are in the focus. Consequently, the volumes are an essential source for researchers in the mentioned fields as well as for teachers preparing courses, e.g., in Bioinorganic Chemistry.

Author : Michael T. McMahon,Assaf A. Gilad,Jeff W.M. Bulte,Peter C.M. van Zijl
Publisher : CRC Press
Page : 496 pages
File Size : 51,6 Mb
Release : 2017-01-12
Category : Medical
ISBN : 9781315340753

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Chemical Exchange Saturation Transfer Imaging by Michael T. McMahon,Assaf A. Gilad,Jeff W.M. Bulte,Peter C.M. van Zijl Pdf

This is the first textbook dedicated to CEST imaging and covers the fundamental principles of saturation transfer, key features of CEST agents that enable the production of imaging contrast, and practical aspects of preparing image-acquisition and post-processing schemes suited for in vivo applications. CEST is a powerful MRI contrast mechanism with unique features, and the rapid expansion it has seen over the past 15 years since its original discovery in 2000 has created a need for a graduate-level handbook describing all aspects of pre-clinical, translational, and clinical CEST imaging. The book provides an illustrated historical perspective by leaders at the five key sites who developed CEST imaging, from the initial saturation transfer NMR experiments performed in the 1960s in Stockholm, Sweden, described by Sture Forsén, to the work on integrating the basic principles of CEST into imaging by Robert Balaban, Dean Sherry, Silvio Aime, and Peter van Zijl in the United States and Italy. The editors, Drs. Michael T. McMahon, Assaf A. Gilad, Jeff W. M. Bulte, and Peter C. M. van Zijl, have been pioneers developing this field at the Johns Hopkins University School of Medicine and the Kennedy Krieger Institute including contributions to Nature Medicine, Nature Biotechnology, Nature Materials, and the Proceedings of the National Academy of Sciences. As recognition for their initial development of the field, Drs. van Zijl and Balaban were awarded the Laukien Prize in April 2016, established in 1999 to honor the memory of Professor Gunther Laukien, a co-founder of Bruker Biospin GmbH.

Author : Renata Jastrzab,Bartosz Tylkowski
Publisher : Walter de Gruyter GmbH & Co KG
Page : 188 pages
File Size : 47,5 Mb
Release : 2016-03-21
Category : Technology & Engineering
ISBN : 9783110348903

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New-Generation Bioinorganic Complexes by Renata Jastrzab,Bartosz Tylkowski Pdf

Bio-Inorganic compounds are successfully applied as therapeutic agents since decades. Thus, scientist designed new metal complexes bearing biomolecules as ligands, investigating their potential as bioactive and therapeutic agents. This book presents a comprehensive overview on materials design, substance classes and their characterization. This book is compiled for scientists interested in medical application of bioinspired materials.

Author : Ivano Bertini
Publisher : University Science Books
Page : 794 pages
File Size : 43,9 Mb
Release : 2007
Category : Science
ISBN : 1891389432

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Biological Inorganic Chemistry by Ivano Bertini Pdf

Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II.

Author : Enzo Alessio
Publisher : John Wiley & Sons
Page : 625 pages
File Size : 45,6 Mb
Release : 2011-02-25
Category : Science
ISBN : 9783527633128

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Bioinorganic Medicinal Chemistry by Enzo Alessio Pdf

This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic.

Author : Robert A. Scott,Charles M. Lukehart
Publisher : John Wiley & Sons
Page : 597 pages
File Size : 45,6 Mb
Release : 2013-02-19
Category : Science
ISBN : 9781118625286

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Applications of Physical Methods to Inorganic and Bioinorganic Chemistry by Robert A. Scott,Charles M. Lukehart Pdf

Modern spectroscopic and instrumental techniques are essential to the practice of inorganic and bioinorganic chemistry. This first volume in the new Wiley Encyclopedia of Inorganic Chemistry Methods and Applications Series provides a consistent and comprehensive description of the practical applicability of a large number of techniques to modern problems in inorganic and bioinorganic chemistry. The outcome is a text that provides invaluable guidance and advice for inorganic and bioinorganic chemists to select appropriate techniques, whilst acting as a source to the understanding of these methods. This volume is also available as part of Encyclopedia of Inorganic Chemistry, 5 Volume Set. This set combines all volumes published as EIC Books from 2007 to 2010, representing areas of key developments in the field of inorganic chemistry published in the Encyclopedia of Inorganic Chemistry. Find out more.

Author : Stephen J. Lippard,Jeremy Mark Berg
Publisher : University Science Books
Page : 444 pages
File Size : 48,9 Mb
Release : 1994
Category : Medical
ISBN : 0935702725

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Principles of Bioinorganic Chemistry by Stephen J. Lippard,Jeremy Mark Berg Pdf

The use of unnatural metals - which have been introduced into human biology as diagnostic probes and drugs - is another active area of tremendous medical significance.

Author : Rosette M. Roat-Malone
Publisher : John Wiley & Sons
Page : 352 pages
File Size : 44,6 Mb
Release : 2020-01-31
Category : Science
ISBN : 9781119535232

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Bioinorganic Chemistry by Rosette M. Roat-Malone Pdf

Introduces students to the basics of bioinorganic chemistry This book provides the fundamentals for inorganic chemistry and biochemistry relevant to understanding bioinorganic topics. It provides essential background material, followed by detailed information on selected topics, to give readers the background, tools, and skills they need to research and study bioinorganic topics of interest to them. To reflect current practices and needs, instrumental methods and techniques are referred to and mixed in throughout the book. Bioinorganic Chemistry: A Short Course, Third Edition begins with a chapter on Inorganic Chemistry and Biochemistry Essentials. It then continues with chapters on: Computer Hardware, Software, and Computational Chemistry Methods; Important Metal Centers in Proteins; Myoglobins, Hemoglobins, Superoxide Dismutases, Nitrogenases, Hydrogenases, Carbonic Anhydrases, and Nitrogen Cycle Enzymes. The book concludes with chapters on Nanobioinorganic Chemistry and Metals in Medicine. Readers are also offered end-of-section summaries, conclusions, and thought problems. Reduces size of the text from previous edition to match the first, keeping it appropriate for a one-semester course Offers primers and background materials to help students feel comfortable with research-level bioinorganic chemistry Emphasizes select and diverse topics using extensive references from current scientific literature, with more emphasis on molecular biology in the biochemistry section, leading to a discussion of CRISPR technology Adds new chapters on hydrogenases, carbonic anhydrases, and nitrogen cycle enzymes, along with a separate chapter on nanobioinorganic chemistry Features expanded coverage of computer hardware and software, metalloenzymes, and metals in medicines Supplemented with a companion website for students and instructors featuring Powerpoint and JPEG figures and tables, arranged by chapter Appropriate for one-semester bioinorganic chemistry courses, Bioinorganic Chemistry: A Short Course, Third Edition is ideal for upper-level undergraduate and beginning graduate students. It is also a valuable reference for practitioners and researchers in need of a general introduction to the subject, as well as chemists requiring an accessible reference.

Author : Kourosh Honarmand Ebrahimi,Simone Ciofi Baffoni,Peter-Leon Hagedoorn
Publisher : Frontiers Media SA
Page : 153 pages
File Size : 52,8 Mb
Release : 2023-05-31
Category : Science
ISBN : 9782832524206

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Bioinorganic Chemistry of Metals in Cell Function and Disease by Kourosh Honarmand Ebrahimi,Simone Ciofi Baffoni,Peter-Leon Hagedoorn Pdf

Author : Jack Yarwood,Richard Douthwaite,Simon Duckett
Publisher : Royal Society of Chemistry
Page : 334 pages
File Size : 41,9 Mb
Release : 2010-08-01
Category : Science
ISBN : 9781849730853

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Spectroscopic Properties of Inorganic and Organometallic Compounds by Jack Yarwood,Richard Douthwaite,Simon Duckett Pdf

Spectroscopic Properties of Inorganic and Organometallic Compounds: Techniques, Materials and Applications provides a unique source of information in an important area of chemistry.