Integrative Approaches To The Molecular Physiology Of Inflammation

Author : Enrique Hernández-Lemus,María Elena Soto,Carlos Rosales
Publisher : Frontiers Media SA
Page : 334 pages
File Size : 53,7 Mb
Release : 2019-04-02
Category : Electronic
ISBN : 9782889458004

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Integrative Approaches to the Molecular Physiology of Inflammation by Enrique Hernández-Lemus,María Elena Soto,Carlos Rosales Pdf

"Integrative Approaches to the Molecular Physiology of Inflammation" presents contributions from the many different fields and approaches to the physiology and the molecular origins of inflammation; particularly those that may be involved in the development and evolution of diseased phenotypes. We selected among the wide scope and multiple views used to probe into the molecular origins of complex inflammatory phenotypes. This book consists of an Introductory Editorial and 6 thematic chapters encompassing 24 articles: 17 original research contributions and 7 review articles (5 reviews, 1 systematic review, and 1 minireview). Both, the research papers and the reviews provide varied and insightful approaches to different facets of inflammation with approaches ranging from general inflammation and signaling depictions deeply rooted on functional biology and physiology, to computational systems biology analyses, translational medicine, and pharmacological explorations. Model systems are also quite diverse: human subjects, mice and other mammal models, cell cultures and in silico, complex networks and database studies.

Author : Elvira Forte,Isotta Chimenti,Gonzalo del Monte-Nieto,Susanne Sattler
Publisher : Frontiers Media SA
Page : 369 pages
File Size : 55,8 Mb
Release : 2022-02-23
Category : Science
ISBN : 9782889744978

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Fibrosis and Inflammation in Tissue Pathophysiology by Elvira Forte,Isotta Chimenti,Gonzalo del Monte-Nieto,Susanne Sattler Pdf

Author : Mieczyslaw Pokorski
Publisher : Springer Science & Business Media
Page : 353 pages
File Size : 53,7 Mb
Release : 2012-07-27
Category : Medical
ISBN : 9789400745490

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Respiratory Regulation - The Molecular Approach by Mieczyslaw Pokorski Pdf

This book, an international collaborative effort in the area of molecular respiratory research, showcases a broad range of multidisciplinary approaches to unravel and analyze the underlying mechanisms of a spectrum of respiratory ailments. It discusses immunological and genetic respiratory disorders, cancer, respiratory allergies and cough, sleep disordered breathing and many others. Exciting new results and up-to-date critical overviews of widely debated topics pertaining to respiratory disorders are presented. The contributions provide evidence for the growing interest of the international community of researchers in the field of respiration. The book incorporates modern molecular approaches to diagnostic and treatment solutions, underscoring the need for rational, evidence-based treatment methods. Combining cutting edge basic and clinical research with expert knowledge and experience this book is essential reading for medical students, research scientists and practicing specialists in pulmonology, immunology and allergology.

Author : Timothy R Deer,Michael S Leong,Asokumar Buvanendran,Vitaly Gordin,Philip S. Kim,Sunil J. Panchal,Albert L. Ray
Publisher : Springer Science & Business Media
Page : 1084 pages
File Size : 54,7 Mb
Release : 2013-02-11
Category : Medical
ISBN : 9781461415602

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Comprehensive Treatment of Chronic Pain by Medical, Interventional, and Integrative Approaches by Timothy R Deer,Michael S Leong,Asokumar Buvanendran,Vitaly Gordin,Philip S. Kim,Sunil J. Panchal,Albert L. Ray Pdf

Edited by master clinician-experts appointed by the American Academy of Pain Medicine, this is a state-of-the-art multidisciplinary textbook covering medical, interventional, and integrative approaches to the treatment and management of pain. It is designed as a practical and comprehensive primary reference for busy physicians and is also an up-to-date resource for preparing for certification examinations in pain medicine. · Written and edited by world-class authorities · “Key Points” preview contents of each chapter · Leading edge medical topics, such as monitoring opioid use and abuse, and the emerging role of cannabinoids in pain treatment · Expert guidance on full range of interventional techniques · Clinical anatomy and physiology for the interventionist · Behavioral dimensions of the experience and management of pain · Integrative approaches for treating the “whole person” · Legal issues, such as failure to treat pain · First-hand patient accounts

Author : Carla Maria Pedrosa Ribeiro,Noel Gerard McElvaney,Giulio Cabrini
Publisher : Frontiers Media SA
Page : 286 pages
File Size : 42,9 Mb
Release : 2022-01-04
Category : Science
ISBN : 9782889719419

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Novel Anti-inflammatory Approaches for Cystic Fibrosis Lung Disease: Identification of Molecular Targets and Design of Innovative Therapies by Carla Maria Pedrosa Ribeiro,Noel Gerard McElvaney,Giulio Cabrini Pdf

Author : Institute of Medicine
Publisher : National Academies Press
Page : 245 pages
File Size : 48,9 Mb
Release : 2009-10-16
Category : Medical
ISBN : 9780309147316

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Integrative Medicine and the Health of the Public by Institute of Medicine Pdf

The last century witnessed dramatic changes in the practice of health care, and coming decades promise advances that were not imaginable even in the relatively recent past. Science and technology continue to offer new insights into disease pathways and treatments, as well as mechanisms of protecting health and preventing disease. Genomics and proteomics are bringing personalized risk assessment, prevention, and treatment options within reach; health information technology is expediting the collection and analysis of large amounts of data that can lead to improved care; and many disciplines are contributing to a broadening understanding of the complex interplay among biology, environment, behavior, and socioeconomic factors that shape health and wellness. On February 25 - 27, 2009, the Institute of Medicine (IOM) convened the Summit on Integrative Medicine and the Health of the Public in Washington, DC. The summit brought together more than 600 scientists, academic leaders, policy experts, health practitioners, advocates, and other participants from many disciplines to examine the practice of integrative medicine, its scientific basis, and its potential for improving health. This publication summarizes the background, presentations, and discussions that occurred during the summit.

Author : Philippe Connes,Olivier Hue,Stéphane Perrey
Publisher : IOS Press
Page : 692 pages
File Size : 45,6 Mb
Release : 2010
Category : Medical
ISBN : 9781607504962

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Exercise Physiology by Philippe Connes,Olivier Hue,Stéphane Perrey Pdf

There is no doubt that if the field of exercise physiology is to make further advancements, the various specialized areas must work together in solving the unique and difficult problems of understanding how exercise is initiated, maintained and regulated at many functional levels, and what causes us to quit. Exercise is perhaps the most complex of physiological functions, requiring the coordinated, integrated activation of essentially every cell, tissue and organ in the body. Such activation is known to take place at all levels - from molecular to systemic. Focusing on important issues addressed at cellular and systemic levels, this handbook presents state-of-the-art research in the field of exercise physiology. Each chapter serves as a comprehensive resource that will stimulate and challenge discussion in advanced students, researchers, physiologists, medical doctors and practitioners. Authored by respected exercise physiologists from nineteen countries, each chapter has been significantly updated to provide up-to-date coverage of the topics and to offer complete descriptions of the many facets of the most physiological responses from a cellular to an integrative approach within individual body systems in normal and disease states and includes some chapters that are rarely addressed in exercise physiology books, such as the influence of exercise on endothelium, vasomomotor control mechanisms, coagulation, immune function and rheological properties of blood, and their influence on hemodynamics. This book represents the first iteration to provide such a work. Normal exercise responses divided into muscle function, bioenergetics, and respiratory, cardiac and blood/vascular function; Fitness, training, exercise testing and limits to exercise; Exercise responses in different environments; Beneficial effects of exercise rehabilitation on ageing and in the prevention and treatment of disease states; Rarely addressed issues such as the influence of exercise on endothelium, vasomotor control mechanisms, coagulation, immune function and rheological properties of blood and their influence on hemodynamics. IOS Press is an international science, technical and medical publisher of high-quality books for academics, scientists, and professionals in all fields. Some of the areas we publish in: -Biomedicine -Oncology -Artificial intelligence -Databases and information systems -Maritime engineering -Nanotechnology -Geoengineering -All aspects of physics -E-governance -E-commerce -The knowledge economy -Urban studies -Arms control -Understanding and responding to terrorism -Medical informatics -Computer Sciences

Author : Yoram Vodovotz,Gary An
Publisher : Springer Nature
Page : 307 pages
File Size : 41,7 Mb
Release : 2020-11-04
Category : Medical
ISBN : 9783030565107

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Complex Systems and Computational Biology Approaches to Acute Inflammation by Yoram Vodovotz,Gary An Pdf

This second edition expands upon and updates the vital research covered in its predecessor, by presenting state-of-the-art multidisciplinary and systems-oriented approaches to complex diseases arising from and driven by the acute inflammatory response. The chapters in this volume provide an introduction to different types of computational modeling, and how these methods can be applied to specific inflammatory diseases, with a focus on providing readers a roadmap for integrating advanced mathematical and computational techniques with traditional experimental methods. In this second edition, we cover both well-established and emerging modeling methods, especially state-of-the-art machine learning approaches and the integration of data-driven and mechanistic modeling. This volume introduces the concept of Model-based Precision Medicine as an alternative approach to the current view of Precision Medicine, based on leveraging mechanistic computational modeling to decrease cost while increasing the information value of the data being obtained. By presenting the role of computational modeling as an integrated component of the research process, Complex Systems and Computational Biology Approaches to Acute Inflammation: A Framework for Model-based Precision Medicine offers a window into the recent past, the present, and the future of computationally-augmented biomedical research.

Author : Alexander Mauro
Publisher : Raven Press (ID)
Page : 582 pages
File Size : 48,9 Mb
Release : 1979
Category : Medical
ISBN : UOM:39015015064226

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Muscle Regeneration by Alexander Mauro Pdf

Author : Rajkumar Rajendram,Victor R Preedy,Colin R Martin
Publisher : Academic Press
Page : 558 pages
File Size : 54,7 Mb
Release : 2022-05-10
Category : Medical
ISBN : 9780128224281

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Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury by Rajkumar Rajendram,Victor R Preedy,Colin R Martin Pdf

Spinal injury affects about 10 million people annually worldwide, impacting on the family unit and causing lifelong disabilities, with varied symptoms including paresthesia, spasticity, loss of motor control, and often severe pain. Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury will enhance readers’ understanding of the biological and psychological effects of spinal cord injury. Featuring chapters on gene expression, metabolic effects, and behavior, this volume discusses in detail the impact of spinal cord injury to better understand the underlying pathways and processes. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand these injuries. Summarizes the neuroscience of spinal cord injury, including cellular and molecular biology Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding Features chapters on signaling and hormonal events Includes plasticity and gene expression Examines health and stress behaviors after spinal cord injury

Author : Robert Fitridge,M. M. Thompson
Publisher : University of Adelaide Press
Page : 589 pages
File Size : 45,9 Mb
Release : 2011
Category : Medical
ISBN : 9781922064004

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Mechanisms of Vascular Disease by Robert Fitridge,M. M. Thompson Pdf

New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Author : Anonim
Publisher : Unknown
Page : 1732 pages
File Size : 54,5 Mb
Release : 1995
Category : Medicine
ISBN : OSU:32436010300489

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Cumulated Index Medicus by Anonim Pdf

Author : D. Neil Granger,Elena Senchenkova
Publisher : Morgan & Claypool Publishers
Page : 99 pages
File Size : 45,6 Mb
Release : 2010
Category : Medical
ISBN : 9781615041657

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Inflammation and the Microcirculation by D. Neil Granger,Elena Senchenkova Pdf

The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References

Author : Anonim
Publisher : Unknown
Page : 1780 pages
File Size : 50,6 Mb
Release : 2003
Category : Medicine
ISBN : MINN:31951P00880599I

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Index Medicus by Anonim Pdf

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Author : Alexzander A. A. Asea,Punit Kaur
Publisher : Springer
Page : 315 pages
File Size : 42,6 Mb
Release : 2018-10-24
Category : Science
ISBN : 9783319907253

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Heat Shock Proteins and Stress by Alexzander A. A. Asea,Punit Kaur Pdf

The book Heat Shock Proteins and Stress provides the most comprehensive review on contemporary knowledge on the role of HSP in Stress. Using an integrative approach to understanding the regulation of HSP responses, the contributors provide a synopsis of novel mechanisms by which HSP responses are regulated under normal physiological and pathophysiological conditions. Key basic and clinical research laboratories from major universities and academic medical hospitals around the world contribute chapters that review present research activity and importantly project the field into the future. The book is a must read for researchers, postdoctoral fellows and graduate students in the fields of Translational Medicine, Clinical Psychologists, Human Physiology, Zoologists, Botanists, Biotechnology, Molecular Medicine, Infectious Diseases Experts and Pathologists.