Interleukins In Cancer Biology

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Interleukins in Cancer Biology

Arseniy Yuzhalin,Anton Kutikhin
Interleukins in Cancer Biology Book PDF

Author : Arseniy Yuzhalin,Anton Kutikhin
Publisher : Academic Press
Page : 356 pages
File Size : 51,5 Mb
Release : 2014-06-27
Category : Medical
ISBN : 9780128013335

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Interleukins in Cancer Biology by Arseniy Yuzhalin,Anton Kutikhin Pdf

Interleukins in Cancer Biology responds to the growing need for credible and up-to-date information about the impact of interleukins on occurrence, development and progression of cancer. It provides reliable information about all known interleukins (38), describes recent discoveries in the field, and moreover, suggests further directions of research on the most promising aspects of this topic. The structure and presentation of the work is very understandable and clear with attention to detail maintained throughout. There are multiple illustrations throughout to help in comprehending and remembering the most important facts. . Summarizes and discusses existing facts on the impact of all known interleukins in occurrence, development, and progression of cancer Categorizes and clarifies all interleukins based on their role in cancer Contains comprehensive and exhaustive information on each molecule

Tumor Microenvironment

Alexander Birbrair
Tumor Microenvironment Book PDF

Author : Alexander Birbrair
Publisher : Springer Nature
Page : 122 pages
File Size : 50,9 Mb
Release : 2020-02-14
Category : Science
ISBN : 9783030383152

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Tumor Microenvironment by Alexander Birbrair Pdf

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of interleukins in the tumor microenvironment. Each chapter focuses on the various ways to target the tumor microenvironment by intervention in the interleukin biology, including IL-1, IL-8, IL-21, IL-36 signaling, and more. Taken alongside its companion volumes, Tumor Microenvironment: The Role of Interleukins – Part A updates us on what we know about various aspects of the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Tumor Microenvironment

Anonim
Tumor Microenvironment Book PDF

Author : Anonim
Publisher : Unknown
Page : 122 pages
File Size : 54,9 Mb
Release : 2020
Category : Cancer
ISBN : 3030383164

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Tumor Microenvironment by Anonim Pdf

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of interleukins in the tumor microenvironment. Each chapter focuses on the various ways to target the tumor microenvironment by intervention in the interleukin biology, including IL-1, IL-8, IL-21, IL-36 signaling, and more. Taken alongside its companion volumes, Tumor Microenvironment: The Role of Interleukins - Part A updates us on what we know about various aspects of the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment. --

Tumor Microenvironment

Alexander Birbrair
Tumor Microenvironment Book PDF

Author : Alexander Birbrair
Publisher : Springer Nature
Page : 142 pages
File Size : 53,5 Mb
Release : 2021-02-09
Category : Medical
ISBN : 9783030556174

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Tumor Microenvironment by Alexander Birbrair Pdf

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of interleukins in the tumor microenvironment. Each chapter focuses on the various ways to target the tumor microenvironment by intervention in the interleukin biology, including IL-6, IL-7, IL-10, IL-12, IL-22, IL-23, and IL-24 signaling. Taken alongside its companion volumes, Tumor Microenvironment: The Role of Interleukins – Part B updates us on what we know about various aspects of the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Tumor Microenvironment

Alexander Birbrair
Tumor Microenvironment Book PDF

Author : Alexander Birbrair
Publisher : Unknown
Page : 134 pages
File Size : 53,6 Mb
Release : 2021
Category : Cancer
ISBN : 3030556182

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Tumor Microenvironment by Alexander Birbrair Pdf

"Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of interleukins in the tumor microenvironment. Each chapter focuses on the various ways to target the tumor microenvironment by intervention in the interleukin biology, including IL-6, IL-7, IL-10, IL-12, IL-22, IL-23, and IL-24 signaling. Taken alongside its companion volumes, Tumor Microenvironment: The Role of Interleukins Part Bupdates us on what we know about various aspects of the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment."--Publisher's description.

Cytokines: Interleukins and Their Receptors

Razelle Kurzrock,Moshe Talpaz
Cytokines Interleukins and Their Receptors Book PDF

Author : Razelle Kurzrock,Moshe Talpaz
Publisher : Springer Science & Business Media
Page : 388 pages
File Size : 50,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461312413

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Cytokines: Interleukins and Their Receptors by Razelle Kurzrock,Moshe Talpaz Pdf

Over the last decade, cytokine research has emerged as one of the most exciting and critical fields for providing fundamental knowledge of normal and abnormal human development. Today, it is apparent that cytokines orchestrate growth from the early embryonic stage to maturity and are responsible for the normal function of virtually every organ system. Furthermore, virtually all disease states have been associated, at least in part, with cytokine aberrations. In this volume, the editors have brought together internationally known experts in the field of interleukin research to provide a comprehensive review of the biology of the interleukins and their role in both health and illness, while maintaining a balance between the basic science and clinical aspects. Cytokines: Interleukins and their Receptors should be of interest to a wide variety of researchers including clinical hematologists, oncologists, immunologists, in addition to medical and PhD students and researchers with an interest in cytokines.

Interleukin-2 and Killer Cells in Cancer

Eva Lotzova
Interleukin 2 and Killer Cells in Cancer Book PDF

Author : Eva Lotzova
Publisher : CRC Press
Page : 381 pages
File Size : 53,6 Mb
Release : 2018-02-01
Category : Science
ISBN : 9781351082242

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Interleukin-2 and Killer Cells in Cancer by Eva Lotzova Pdf

This is the first-and only-publication available which provides the most recent information in this particular field of biomedicine. Interleukin-2 (IL-2) and IL-2 activated killer cells have been shown to have a potential in the treatment of a variety of human malignant diseases. This work comprehensively summarizes basic aspects of IL-2 as well as its clinical application, therefore making all these aspects easily accessible to the readers. Because of the clinical significance of this molecule in the treatment of cancer, the basic and clinical investigations in the IL-2 field are rapidly expanding, together with the interest of the scientific and medical community. This book is an excellent educational and teaching tool for scientists, clinicians, and students. Those who already have expertise in research in the IL-2 area will find this reference indispensible.

The Cytokine Handbook, Two-Volume Set

Angus W. Thomson,Michael T. Lotze
The Cytokine Handbook Two Volume Set Book PDF

Author : Angus W. Thomson,Michael T. Lotze
Publisher : Elsevier
Page : 1572 pages
File Size : 40,7 Mb
Release : 2003-04-22
Category : Medical
ISBN : 0080518796

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The Cytokine Handbook, Two-Volume Set by Angus W. Thomson,Michael T. Lotze Pdf

The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes, co-edited by Michael T Lotze, and written by over 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for researchers and clinicians interested in cytokines, including anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics. Key Features * Covers all main cytokines and chemokines * Written by experts * Up-to-date- includes detailed referencing accessing current, modern literature and reflects the newest findings from the human genome * The new edition has been thoroughly revised and extended (now 2 volumes) as compared to the last edition, including new co-editor (MTL), new authors, new hot topics and new chapters * Includes major emphasis on clinical applications * Extensively illustrated with tables and figures

The Biology and Clinical Applications of Interleukin-2

Robert C. Rees
The Biology and Clinical Applications of Interleukin 2 Book PDF

Author : Robert C. Rees
Publisher : IRL Press
Page : 208 pages
File Size : 48,7 Mb
Release : 1990
Category : Medical
ISBN : UOM:39015019819179

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The Biology and Clinical Applications of Interleukin-2 by Robert C. Rees Pdf

The molecular structure of interleukin-2 (IL-2) and that of its receptor subunits provide a basis for understanding lymphocyte activation by IL-2 and the generation of effector cells capable of mediating cytotoxicity towards tumors. This book provides an up-to-date account of IL-2, its effect on lymphocyte function, and clinical applications. Internationally know experts review the molecular aspects of cell signalling, giving insight on the in vivo pathways of activation likely to be important in determining clinical responses. They also examine the use of cytokines, particularly IL-2, in the treatment of cancer, and describe the results of recent clinical trials using IL-2, as well as of adoptive cell therapy. Providing a clear account of recent progress, the book also reviews the problems involved in attempting to improve the therapeutic benefit of IL-2, along with the importance of mechanisms which subverse IL-2 responses. This is the most up-to-date account of molecular research and clinical trials in this area, and will be of great benefit to students and researchers in immunology, pharmacology, biochemistry, and oncology who are interested in this vitally important topic.

Multifaceted Role of IL-1 in Cancer and Inflammation

Manisha Singh
Multifaceted Role of IL 1 in Cancer and Inflammation Book PDF

Author : Manisha Singh
Publisher : Elsevier
Page : 194 pages
File Size : 53,5 Mb
Release : 2023-06-07
Category : Science
ISBN : 9780323859677

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Multifaceted Role of IL-1 in Cancer and Inflammation by Manisha Singh Pdf

Multifaceted Role of IL-1 in Cancer and Inflammation summarizes the existing literature and discusses future perspectives about the role of IL-1 in immune suppression, cancer progression, angiogenesis, and resistance to immunotherapies. The book presents mechanisms to overcome IL-1 mediated immune suppression in tumor microenvironment and covers topics on the source of IL-1 in the tumor microenvironment, IL-1 mediated downstream pathway, mechanism of IL-1 mediated immune suppression in cancer, and its effect on immunotherapy of cancer. Those topics help readers understand the effect of IL-1 on cancer immunopathology and immunotherapy, and provide them with broader concepts to develop therapies for IL-1 enrichment tumors. This is a valuable source for cancer researchers, clinicians and other members of the biomedical field who wants to learn more about mechanisms to improve outcome of cancer immunotherapies. Presents a summary in the beginning of each chapter to help readers to find the needed information and understand the content easily Encompasses detailed schematic diagrams and illustrations throughout the content to explain the complex immune mechanisms discussed Discusses future perspectives in all chapters to motivate researchers to work on emerging problems Includes contributions from internationally renown experts sharing their experiences on clinics and research

The Cytokine Handbook

Angus W. Thomson,Michael T. Lotze
The Cytokine Handbook Book PDF

Author : Angus W. Thomson,Michael T. Lotze
Publisher : Unknown
Page : 0 pages
File Size : 49,5 Mb
Release : 2003
Category : Chemokines
ISBN : 0126896658

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The Cytokine Handbook by Angus W. Thomson,Michael T. Lotze Pdf

Several thousand of the 38,000 genes in the human genome, including the cytokines and chemokines, regulate and co-ordinate cell-cell interaction in health and disease. Cytokines play a key role in biology through highly specific receptors and this handbook considers their implications. Provides an encyclopedic coverage of the molecules that induce and regulate immune responses. The scope has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for researchers and clinicians interested in cytokines, including anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics.

The role of interleukin-2 in the treatment of cancer patients

J. Wagstaff
The role of interleukin 2 in the treatment of cancer patients Book PDF

Author : J. Wagstaff
Publisher : Springer
Page : 191 pages
File Size : 49,9 Mb
Release : 2012-10-29
Category : Medical
ISBN : 9401047693

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The role of interleukin-2 in the treatment of cancer patients by J. Wagstaff Pdf

Recombinant human interleukin-2 became available for clinical use in the mid 1980s. Recent years have seen an enormous amount of clinical research with this cytokine and interleukin-2 has now been registered for use in a number of European countries for the treatment of metastatic renal cell carcinoma. This book is designed to provide the clinical oncologist wishing to use interleukin-2 with a basic background concerning the biology of the agent, a discussion concerning practical aspects, of its clinical use including management of toxicity and an overview of the clinical results together with a description of how this internesting cytokine might be developed in the future.

Interleukin-2 and Killer Cells in Cancer

Eva Lotzova
Interleukin 2 and Killer Cells in Cancer Book PDF

Author : Eva Lotzova
Publisher : CRC Press
Page : 384 pages
File Size : 50,6 Mb
Release : 1989-12-21
Category : Science
ISBN : 0849353882

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Interleukin-2 and Killer Cells in Cancer by Eva Lotzova Pdf

This is the first-and only-publication available which provides the most recent information in this particular field of biomedicine. Interleukin-2 (IL-2) and IL-2 activated killer cells have been shown to have a potential in the treatment of a variety of human malignant diseases. This work comprehensively summarizes basic aspects of IL-2 as well as its clinical application, therefore making all these aspects easily accessible to the readers. Because of the clinical significance of this molecule in the treatment of cancer, the basic and clinical investigations in the IL-2 field are rapidly expanding, together with the interest of the scientific and medical community. This book is an excellent educational and teaching tool for scientists, clinicians, and students. Those who already have expertise in research in the IL-2 area will find this reference indispensible.

Interleukin-2

Jonathan Waxman,FR Balkwill
Interleukin 2 Book PDF

Author : Jonathan Waxman,FR Balkwill
Publisher : Wiley-Blackwell
Page : 256 pages
File Size : 50,6 Mb
Release : 1992-11-16
Category : Medical
ISBN : 0632030429

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Interleukin-2 by Jonathan Waxman,FR Balkwill Pdf

Interleukin-2 "supercharges" the immune system by promoting the growth of activated T-lymphocytes and augmenting their cell-killing activities. It, therefore, has a role in cancer and infection and has been licensed for use in the former. The book will focus on the areas of molecular biology, immunoregulation and the generation of specific or non-specific cytotoxic effector cells and their role in tumour immunotherapy. Dr Balkwill is one of the UK's leading experts in cytokine research and Dr Waxman is an experienced oncologist working with cytokines in a clinical setting. The book will therefore be balanced between a scientific and a clinical angle

The Interleukins

Steven Gillis
The Interleukins Book PDF

Author : Steven Gillis
Publisher : Springer Science & Business Media
Page : 305 pages
File Size : 41,8 Mb
Release : 2013-03-14
Category : Medical
ISBN : 9781468448382

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The Interleukins by Steven Gillis Pdf

Investigations of the activation, proliferation, and, in some cases, differentia tion of mononuclear cells involved in the immune response are proceeding rapidly. These studies have resulted in the discovery of several factors that promote these cellular events, some of which have been characterized biochemically to various extents. Because of the considerable interest in understanding these cellular changes at the molecular level, we chose to produce the first thematic volume for Contemporary Topics in Molecular Immunology; the theme deals with certain regulatory factors that promote proliferation and differentiation. We have com piled contributions from numerous scientists well known for their work with several regulatory factors. In the following paragraphs, the reader will find an overview of the contents of this volume. Greene and Robb review data they have generated over the past 2-3 years with respect to characterization of hormone-specific Interleukin-2 (IL-2) recep tors on the surface of activated T cells. Their chapter traces the development of a quantitative assay for assessment of IL-2 receptors based on the preparation and use of radiolabeled IL-2 prepared biosynthetically with the aid of IL-2-pro ducer leukemic cells. The authors then describe an alternate approach, the prep aration of a monoclonal antibody previously determined to be directed against a T -cell-activation antigen. This so-called anti-Tac antibody was later found to recognize a determinant on or near the IL-2 receptor.