Intracellular Pathogens I

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 51,7 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Ming Tan,Patrik Bavoil
Publisher : American Society for Microbiology Press
Page : 545 pages
File Size : 45,5 Mb
Release : 2012-09-15
Category : Science
ISBN : 9781555816742

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Intracellular Pathogens I by Ming Tan,Patrik Bavoil Pdf

A current review of basic research on Chlamydiales biology and pathogenesis in one comprehensive volume. • Details the scientific knowledge about how these obligate intracellular bacteria invade, survive and replicate inside eukaryotic cells. • Describes the spectrum of disease caused by an infection including protective and pathologic immune responses. • Describes the latest developments, including genomics and biomathematical modeling, and progress towards genetic tools and a vaccine. • Serves as a significant research book for scientists, physicians, medical students, public health professionals, epidemiologists, biocomputational scientists and government policy makers.

Author : Ulrich E. Schaible,Albert Haas
Publisher : John Wiley & Sons
Page : 736 pages
File Size : 41,8 Mb
Release : 2009-09-22
Category : Science
ISBN : 9783527629183

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Intracellular Niches of Microbes by Ulrich E. Schaible,Albert Haas Pdf

The book describes the different and exciting pathways which havebeen developed by pathogenic microbes to manage living inside hostcells. It covers intracellular life styles of all relevantpathogenic but also symbiotic microorganisms with respect to thecell biology of the host-microbe interactions and the microbialadaptations for intracellular survival. It features intracellulartrafficking pathways and characteristics of intracellular niches ofindividual microbes. The book also asks questions on the benefitsfor the microbe with regard to physiological needs and nutritionalaspects such as auxotrophy, effects on genome sizes, andconsequences for disease and host response/immunity (and thebenefits for the host in the cases of symbionts). Additionally, the book includes those pathogens that are medicallyless important but represent distinct intracellular niches,trafficking behaviours and virulence traits. The individualchapters also point out future challenges of research for therespective organism.

Author : Lois J. Paradise,Herman Friedman,Mauro Bendinelli
Publisher : Springer Science & Business Media
Page : 302 pages
File Size : 47,7 Mb
Release : 2006-04-11
Category : Medical
ISBN : 9780306468094

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Opportunistic Intracellular Bacteria and Immunity by Lois J. Paradise,Herman Friedman,Mauro Bendinelli Pdf

Opportunistic, intracellular bacterial infections are at the forefront of research because of the challenges they present to immunocompromised patients. In this volume, the pathogenesis and immune reaction of these intracellular infections is featured, as are the most typical problems related to antimicrobial chemotherapy, and current approaches to their solution. Individual chapters set the pace for research on pathogenic and immune reactions to such infections as, mycobacterium tuberculosis, legionella pneumophila, chlamydia trachomatis and brucella.

Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 52,9 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570

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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Author : Ward E. Bullock,Nabil Hanna,Toby K. Eisenstein
Publisher : Springer
Page : 389 pages
File Size : 55,8 Mb
Release : 2014-11-14
Category : Medical
ISBN : 9781475754216

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Host Defenses and Immunomodulation to Intracellular Pathogens by Ward E. Bullock,Nabil Hanna,Toby K. Eisenstein Pdf

This conference was held under the sponsorship of the Eastern Pennsylvania Branch of the American Society for Microbiology, as one in a continuing series of Basic Science Symposia. The untiring volunteer effects of the members of the Symposium Committee are deeply appreciated. The Bureau of Laboratories of the Pennsylvania Department of Health was a cosponsor and generously provided staff and secretarial services to handle the difficult task of registration. The Department of Microbiology and of Microbiology and Immunology at the five medical schools in Philadelphia -- Temple University School of Medicine, Medical College of Pennsylvania, Thomas Jefferson University, Hahnemann University and the University of Pennsylvania -- were academic cosponsors, and the support of the Chairpersons and the faculties are gratefully acknowledged.

Author : Jean-Pierre Gorvel
Publisher : Springer Science & Business Media
Page : 328 pages
File Size : 53,5 Mb
Release : 2004-01-31
Category : Medical
ISBN : 0306478331

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Intracellular Pathogens in Membrane Interactions and Vacuole Biogenesis by Jean-Pierre Gorvel Pdf

This book provides information on the molecular interactions between host cell organelles and pathogens, which have developed strategies to survive within infected cells. Chapters are grouped into five sections: I. Endocytosis and phagocytosis. Collectively, the chapters of this section review basic knowledge regarding intracellular organelles are involved in membrane interactions with pathogen-containing vacuoles. II. Professional and non-professional phagocytes. Here the authors describe the major differences between the two host cell types, which can be infected by microorganisms. III. Maturation pathways of bacteria-containing vacuoles. Molecular interactions between vacuoles and intracellular organelles leading to the search of the Holy Grail, the replication niche, are described. IV. Host response. Host cells are able to react against intruders and eventually mount host responses. In these chapters the various types of host response mechanisms against intracellular intruders are reviewed. V. Co-evolution. In these final chapters, the question is addressed of whether knowledge of bacteria-host cell interactions will be acquired fast enough to find the necessary tools for controlling microorganism development.

Author : Kenneth A. Fields,Rey Carabeo,Robert A. Heinzen
Publisher : Frontiers E-books
Page : 121 pages
File Size : 44,9 Mb
Release : 2011-08-11
Category : Electronic
ISBN : 9782889190034

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The obligate intracellular lifestyle by Kenneth A. Fields,Rey Carabeo,Robert A. Heinzen Pdf

Bacterial pathogens whose development is restricted to the interior of eukaryotic cells encounter a unique set of hurdles to be overcome to enable growth. This issue is dedicated to the examination of the unique infection biology associated with this obligate intracellular existence. Distinct approaches to obligate intracellular parasitism will be covered by considering a range of molecular, cellular, and immunological mechanisms governing the overall success of pathogens including Chlamydia, Coxiella, Rickettsia, and Ehrlichia. The overall goal is to provide insight into both microbial and host mechanisms that enable colonization of a specialized intracellular niche.Bacterial pathogens whose development is restricted to the interior of eukaryotic cells encounter a unique set of hurdles to be overcome to enable growth. This issue is dedicated to the examination of the unique infection biology associated with this obligate intracellular existence. Distinct approaches to obligate intracellular parasitism will be covered by considering a range of molecular, cellular, and immunological mechanisms governing the overall success of pathogens including Chlamydia, Coxiella, Rickettsia, and Ehrlichia. The overall goal is to provide insight into both microbial and host mechanisms that enable colonization of a specialized intracellular niche.

Author : Toby K. Eisenstein,Paul Actor,Herman Friedman
Publisher : Springer Science & Business Media
Page : 525 pages
File Size : 46,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468444810

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Host Defenses to Intracellular Pathogens by Toby K. Eisenstein,Paul Actor,Herman Friedman Pdf

The subject matter of this volume was the basis for a confer ence held in Philadelphia in June, 1981, and is an important one in the contemporary area of how the host interacts with micro organisms. In conception, it grew out of a graduate course entitled, "The Infectious Process," which has been taught in the Department of Microbiology and Immunology at Temple University School of Medicine during the past twelve years. This course has explored the broad areas of mechanisms of microbial pathogenesis and host resistance by in-depth consideration of selected models of experimental infection and immunity, as well as the clinical literature. It is noteworthy that there is no adequate text for this material, as the subject matter naturally crosses a wide spectrum of traditional disciplinary lines, encompassing topics as diverse as the mechanisms of action of bacterial toxins, the role of complement and antibody in phagocytosis, and the importance of cross-reacting bacterial polysaccharide antigens in vaccine development. A major portion of the course has always considered "cellular immunity" as it applies to host defenses to intracellular pathogens. It is in this area that the necessity for amalgamation of information from different disciplines is most evident, for one must be intimately concerned with the interactions between the microbe and the phagocyte, both before and after specific immune recognition.

Author : Aneesh Thakur
Publisher : Humana
Page : 0 pages
File Size : 55,8 Mb
Release : 2024-08-02
Category : Science
ISBN : 1071638890

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Intracellular Pathogens by Aneesh Thakur Pdf

This detailed volume presents cutting-edge approaches to study infection, immunity, and intervention strategies against intracellular pathogens. The book explores areas such as how intracellular pathogens infect and survive inside the phagocytes, immunopathological features of infection, evasion of host-induced immune responses, cellular crosstalk in the presence of intracellular pathogens, host innate and adaptive immunity, and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Intracellular Pathogens: Methods and Protocols serves as an ideal guide for researchers who work with intracellular pathogens and want to utilize or refine strategies to study, treat, or controlthem.

Author : Philippa C. Matthews
Publisher : Oxford University Press
Page : 224 pages
File Size : 41,6 Mb
Release : 2017-07-13
Category : Medical
ISBN : 9780191057670

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Tropical Medicine Notebook by Philippa C. Matthews Pdf

The Tropical Medicine Notebook is a new concept in providing a concise overview of the key topics in tropical medicine, using short notes, diagrams, maps, and tables to present the material in an accessible, engaging, memorable, and interesting way. The format is generally a page per topic, with division of each page into subsections by boxes to make it easy to find the relevant information. Cross-referencing is provided to allow quick linking between relevant sections of the book. Providing the key information in bite-size chunks, the Tropical Medicine Notebook is a useful companion to more comprehensive texts. Divided into eight sections; the first five cover infections caused by bacteria, viruses, fungi, protozoa and helminths, followed by a further three which present the topics of vector biology, disease syndromes and envenomation. Where relevant, the section is prefaced by a classification system to provide a logical overview, helping with assimilation of information and highlighting important relationships between organisms. It is an ideal learning and revision guide for students or trainees in infection, microbiology, and tropical medicine, as well as being a useful reference resource for healthcare and laboratory staff across the wide range of disciplines to which infection may present.

Author : Didier Raoult
Publisher : CRC Press
Page : 394 pages
File Size : 42,5 Mb
Release : 1993-07-06
Category : Medical
ISBN : 0849349249

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Antimicrobial Agents and Intracellular Pathogens by Didier Raoult Pdf

Antimicrobial Agents and Intracellular Pathogens is the first book devoted to the relationships among intracellular pathogens, antibiotics, and cells. The book is divided into two sections. Part One describes the effects of antibiotics on uninfected and infected phagocytic cells, the subcellular location of antibiotic compounds, the subcellular compartment of intracellular microorganisms multiplication, and the vectorization of antibiotics. Part Two focuses on intracellular pathogens used as paradigms, including strict intracellular bacteria and antibiotics such as Chlamydia, Rickettsia, Ehrlichia, and Coxiella burnetii; facultative intracellular bacteria and antibiotics such as Legionella and Mycobacteria; and intracellular protozoa and antimicrobial agents, such as Leishmania, Trypnonosoma, and Toxoplasma. This book will be an important reference for microbiologists, clinical microbiologists, infectious disease experts, and researchers in pharmaceutical companies involved in antibiotic development.

Author : Marie-France Carlier
Publisher : Springer Science & Business Media
Page : 434 pages
File Size : 46,6 Mb
Release : 2010-09-23
Category : Medical
ISBN : 9789048193011

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Actin-based Motility by Marie-France Carlier Pdf

Since the discovery of actin by Straub in the 1950’s and the pioneering work of Oosawa on actin self-assembly in helical laments in the 1960’s, many books and conference proceedings have been published. As one of the most essential p- teins in life, essential for movement in organisms rangingfrom bacteria to higher eukaryotes, it is no surprise that actin has fascinated generations of scientists from many different elds. Actin can be considered as a “living treasure” of biology; the kinetics and thermodynamics of self-assembly, the dissipative nature of actin po- merization, the molecular interactions of monomeric and polymerized actin with regulators, the mechanical properties of actin gels, and more recently the force p- ducing motile and morphogenetic processes organized by the actin nanomachine in response to signaling, are all milestones in actin research. Discoveries that directly derive from and provide deeper insight into the fundamental properties of actin are constantly being made, making actin an ever appealing research molecule. At the same time, the explosion in new technologies and techniques in biological sciences has served to attract researchers from an expanding number of disciplines, to study actin. This book presents the latest developments of these new multiscale approaches of force and movement powered by self-assembly processes, with the hope to opening our perspectives on the many areas of actin-based motility research.

Author : Aneesh Thakur
Publisher : Springer Nature
Page : 375 pages
File Size : 52,7 Mb
Release : 2024-06-30
Category : Electronic
ISBN : 9781071638903

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Intracellular Pathogens by Aneesh Thakur Pdf

Author : C.M. Black
Publisher : Karger Medical and Scientific Publishers
Page : 170 pages
File Size : 45,6 Mb
Release : 2013-06-19
Category : Medical
ISBN : 9783318023992

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Chlamydial Infection: A Clinical and Public Health Perspective by C.M. Black Pdf

Chlamydiae are obligate intracellular bacteria that cause one of the most common sexually transmitted infectious diseases in the world. The infection disproportionately impacts women and the highest prevalence of infection is found in adolescents. Most chlamydial infections are asymptomatic. Untreated infections are sources of further spread of infection and can lead to serious consequences including pelvic inflammatory disease, infertility and chronic pelvic pain. Chlamydial infections also increase a person’s susceptibility to HIV and other STDs.Featuring contributions by internationally recognized experts in epidemiology, infectious disease research and chlamydial biology, this book provides up-to-date reviews from a clinical and public health perspective on chlamydia epidemiology and control programs, genomics and pathogenicity, diagnosis, treatment, host immune responses, and the latest on the search for an effective vaccine. Also included are chapters on the impact of chlamydial infection on specific populations such as the lesbian, gay, bisexual and transgender community, and an update on the outbreak in Europe of the invasive chlamydial infection, lymphogranuloma venereum or LGV. This comprehensive publication is intended for clinicians, public health workers and scientists with interest in sexually transmitted diseases, medical microbiology, infectious diseases and clinical research.