Intracellular Pathogens Ii

Author : Guy H. Palmer,Abdu F. Azad
Publisher : American Society for Microbiology Press
Page : 646 pages
File Size : 42,5 Mb
Release : 2012-09-15
Category : Science
ISBN : 9781555816773

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Intracellular Pathogens II by Guy H. Palmer,Abdu F. Azad Pdf

A current review of basic research on Rickettsiales biology and pathogenesis in one comprehensive volume. • Details the scientific knowledge about how these obligate intracellular bacteria invade, survive and replicate inside eukaryotic cells. • Describes the spectrum of disease caused by an infection and the role of vectors in transmission. • Discusses protective and pathologic immune responses and establishment of persistent infection. • Describes the latest developments including genomics and progress in vaccine development. • Serves as a significant research book for scientists, physicians, medical students, public health professionals, epidemiologists, biocomputational scientists and government policy makers.

Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 54,9 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570

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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 52,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Guy Hughes Palmer,Abdu F. Azad
Publisher : Unknown
Page : 443 pages
File Size : 51,8 Mb
Release : 2012
Category : Rickettsial diseases
ISBN : 155581865X

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Intracellular Pathogens II by Guy Hughes Palmer,Abdu F. Azad Pdf

Author : Jean-Pierre Gorvel
Publisher : Springer Science & Business Media
Page : 328 pages
File Size : 47,8 Mb
Release : 2004-01-31
Category : Medical
ISBN : 0306478331

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Intracellular Pathogens in Membrane Interactions and Vacuole Biogenesis by Jean-Pierre Gorvel Pdf

This book provides information on the molecular interactions between host cell organelles and pathogens, which have developed strategies to survive within infected cells. Chapters are grouped into five sections: I. Endocytosis and phagocytosis. Collectively, the chapters of this section review basic knowledge regarding intracellular organelles are involved in membrane interactions with pathogen-containing vacuoles. II. Professional and non-professional phagocytes. Here the authors describe the major differences between the two host cell types, which can be infected by microorganisms. III. Maturation pathways of bacteria-containing vacuoles. Molecular interactions between vacuoles and intracellular organelles leading to the search of the Holy Grail, the replication niche, are described. IV. Host response. Host cells are able to react against intruders and eventually mount host responses. In these chapters the various types of host response mechanisms against intracellular intruders are reviewed. V. Co-evolution. In these final chapters, the question is addressed of whether knowledge of bacteria-host cell interactions will be acquired fast enough to find the necessary tools for controlling microorganism development.

Author : Toby K. Eisenstein,Paul Actor,Herman Friedman
Publisher : Springer Science & Business Media
Page : 525 pages
File Size : 48,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468444810

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Host Defenses to Intracellular Pathogens by Toby K. Eisenstein,Paul Actor,Herman Friedman Pdf

The subject matter of this volume was the basis for a confer ence held in Philadelphia in June, 1981, and is an important one in the contemporary area of how the host interacts with micro organisms. In conception, it grew out of a graduate course entitled, "The Infectious Process," which has been taught in the Department of Microbiology and Immunology at Temple University School of Medicine during the past twelve years. This course has explored the broad areas of mechanisms of microbial pathogenesis and host resistance by in-depth consideration of selected models of experimental infection and immunity, as well as the clinical literature. It is noteworthy that there is no adequate text for this material, as the subject matter naturally crosses a wide spectrum of traditional disciplinary lines, encompassing topics as diverse as the mechanisms of action of bacterial toxins, the role of complement and antibody in phagocytosis, and the importance of cross-reacting bacterial polysaccharide antigens in vaccine development. A major portion of the course has always considered "cellular immunity" as it applies to host defenses to intracellular pathogens. It is in this area that the necessity for amalgamation of information from different disciplines is most evident, for one must be intimately concerned with the interactions between the microbe and the phagocyte, both before and after specific immune recognition.

Author : Ward E. Bullock,Nabil Hanna,Toby K. Eisenstein
Publisher : Springer
Page : 389 pages
File Size : 53,6 Mb
Release : 2014-11-14
Category : Medical
ISBN : 9781475754216

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Host Defenses and Immunomodulation to Intracellular Pathogens by Ward E. Bullock,Nabil Hanna,Toby K. Eisenstein Pdf

This conference was held under the sponsorship of the Eastern Pennsylvania Branch of the American Society for Microbiology, as one in a continuing series of Basic Science Symposia. The untiring volunteer effects of the members of the Symposium Committee are deeply appreciated. The Bureau of Laboratories of the Pennsylvania Department of Health was a cosponsor and generously provided staff and secretarial services to handle the difficult task of registration. The Department of Microbiology and of Microbiology and Immunology at the five medical schools in Philadelphia -- Temple University School of Medicine, Medical College of Pennsylvania, Thomas Jefferson University, Hahnemann University and the University of Pennsylvania -- were academic cosponsors, and the support of the Chairpersons and the faculties are gratefully acknowledged.

Author : Lois J. Paradise,Herman Friedman,Mauro Bendinelli
Publisher : Springer Science & Business Media
Page : 302 pages
File Size : 43,5 Mb
Release : 2006-04-11
Category : Medical
ISBN : 9780306468094

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Opportunistic Intracellular Bacteria and Immunity by Lois J. Paradise,Herman Friedman,Mauro Bendinelli Pdf

Opportunistic, intracellular bacterial infections are at the forefront of research because of the challenges they present to immunocompromised patients. In this volume, the pathogenesis and immune reaction of these intracellular infections is featured, as are the most typical problems related to antimicrobial chemotherapy, and current approaches to their solution. Individual chapters set the pace for research on pathogenic and immune reactions to such infections as, mycobacterium tuberculosis, legionella pneumophila, chlamydia trachomatis and brucella.

Author : Ulrich E. Schaible,Albert Haas
Publisher : Wiley-Blackwell
Page : 0 pages
File Size : 53,6 Mb
Release : 2009-11-16
Category : Science
ISBN : 3527322078

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Intracellular Niches of Microbes by Ulrich E. Schaible,Albert Haas Pdf

The book describes the different and exciting pathways which have been developed by pathogenic microbes to manage living inside host cells. It covers intracellular life styles of all relevant pathogenic but also symbiotic microorganisms with respect to the cell biology of the host-microbe interactions and the microbial adaptations for intracellular survival. It features intracellular trafficking pathways and characteristics of intracellular niches of individual microbes. The book also asks questions on the benefits for the microbe with regard to physiological needs and nutritional aspects such as auxotrophy, effects on genome sizes, and consequences for disease and host response/immunity (and the benefits for the host in the cases of symbionts). Additionally, the book includes those pathogens that are medically less important but represent distinct intracellular niches, trafficking behaviours and virulence traits. The individual chapters also point out future challenges of research for the respective organism.

Author : Ming Tan,Patrik Bavoil
Publisher : American Society for Microbiology Press
Page : 545 pages
File Size : 49,6 Mb
Release : 2012-09-15
Category : Science
ISBN : 9781555816742

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Intracellular Pathogens I by Ming Tan,Patrik Bavoil Pdf

A current review of basic research on Chlamydiales biology and pathogenesis in one comprehensive volume. • Details the scientific knowledge about how these obligate intracellular bacteria invade, survive and replicate inside eukaryotic cells. • Describes the spectrum of disease caused by an infection including protective and pathologic immune responses. • Describes the latest developments, including genomics and biomathematical modeling, and progress towards genetic tools and a vaccine. • Serves as a significant research book for scientists, physicians, medical students, public health professionals, epidemiologists, biocomputational scientists and government policy makers.

Author : Philippa C. Matthews
Publisher : Oxford University Press
Page : 224 pages
File Size : 42,6 Mb
Release : 2017-07-13
Category : Medical
ISBN : 9780191057670

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Tropical Medicine Notebook by Philippa C. Matthews Pdf

The Tropical Medicine Notebook is a new concept in providing a concise overview of the key topics in tropical medicine, using short notes, diagrams, maps, and tables to present the material in an accessible, engaging, memorable, and interesting way. The format is generally a page per topic, with division of each page into subsections by boxes to make it easy to find the relevant information. Cross-referencing is provided to allow quick linking between relevant sections of the book. Providing the key information in bite-size chunks, the Tropical Medicine Notebook is a useful companion to more comprehensive texts. Divided into eight sections; the first five cover infections caused by bacteria, viruses, fungi, protozoa and helminths, followed by a further three which present the topics of vector biology, disease syndromes and envenomation. Where relevant, the section is prefaced by a classification system to provide a logical overview, helping with assimilation of information and highlighting important relationships between organisms. It is an ideal learning and revision guide for students or trainees in infection, microbiology, and tropical medicine, as well as being a useful reference resource for healthcare and laboratory staff across the wide range of disciplines to which infection may present.

Author : R. Ahmed,Irvin Chen
Publisher : Wiley-Blackwell
Page : 754 pages
File Size : 44,5 Mb
Release : 1999
Category : Medical
ISBN : UOM:39015041993448

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Persistent Viral Infections by R. Ahmed,Irvin Chen Pdf

Persistent Viral Infections Edited by Rafi Ahmed Emory Vaccine Center, Atlanta, USA and Irvin S. Y. Chen UCLA School of Medicine, Los Angeles, USA During the past decade much of our attention has focused on diseases associated with viral persistence. Major breakthroughs in immunology, and the advent of molecular approaches to study pathogenesis have increased our understanding of the complex virus-host interactions that occur during viral persistence. Persistent Viral Infections focuses on: * The pathogenesis and immunology of chronic infections * Animal models that provide, or have the potential to provide, major insights This volume will be essential reading for virologists, immunologists, oncologists and neurologists.

Author : Didier Raoult,Philippe Parola
Publisher : CRC Press
Page : 400 pages
File Size : 44,7 Mb
Release : 2007-04-26
Category : Medical
ISBN : 9781420019971

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Rickettsial Diseases by Didier Raoult,Philippe Parola Pdf

The only available reference to comprehensively discuss the common and unusual types of rickettsiosis in over twenty years, this book will offer the reader a full review on the bacteriology, transmission, and pathophysiology of these conditions. Written from experts in the field from Europe, USA, Africa, and Asia, specialists analyze specific patho

Author : Uday Kishore,Taruna Madan,Robert B. Sim
Publisher : Springer Nature
Page : 249 pages
File Size : 47,9 Mb
Release : 2021-03-12
Category : Medical
ISBN : 9783030670481

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The Collectin Protein Family and Its Multiple Biological Activities by Uday Kishore,Taruna Madan,Robert B. Sim Pdf

The topic of this book, Collectins, is a family of proteins whose major function is in innate immunity, where Collectins act as pattern recognition receptors (PRRs). In general they recognize targets such as microbial surfaces and apoptotic cells, and once bound to a target, Collectins promote the clearance of microorganisms and damaged host tissue. New cell-surface proteins and glycoproteins, which act as Collectin receptors, are currently being identified. Some Collectins, particularly MBL, activate the complement system, which enhances the ability of antibodies to fight pathogens, via three MBL-associated proteases, the MASPs. Additionally, recent research has begun to show wider-ranging activities of Collectins, such as: · Their role in metabolism, and therefore their involvement in lifestyle diseases such as obesity and cardiovascular disease. · Their ability to modulate the adaptive immune response, as well as to recognize and trigger apoptosis of cancer cells, which makes them effective in the annihilation of cancer cells with multiple mutations. · The regulation of their expression by gonadal steroid hormones implicates them with critical roles in both male and female fertility. · Altered levels of Collectins have been associated with various autoimmune diseases. This book brings together current knowledge of the structure, functions and biological activities of Collectins, to describe their integral role in human health.

Author : Jost Wingender,Thomas R. Neu,Hans-Curt Flemming
Publisher : Springer Science & Business Media
Page : 266 pages
File Size : 46,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642601477

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Microbial Extracellular Polymeric Substances by Jost Wingender,Thomas R. Neu,Hans-Curt Flemming Pdf

Microbial extracellular polymeric substances (EPS) are the key components for the aggregation of microorganisms in biofilms, flocs and sludge. They are composed of polysaccharides, proteins, nucleic acids, lipids and other biological macromolecules. EPS provide a highly hydrated gel matrix in which microbial cells can establish stable synergistic consortia. Cohesion and adhesion as well as morphology, structure, biological function and other properties such as mechanical stability, diffusion, sorption and optical properties of microbial aggregates are determined by the EPS matrix. Also, the protection of biofilm organisms against biocides is attributed to the EPS. Their matrix allows phase separation in biofiltration and is also important for the degradation of particulate material which is of great importance for the self purification processes in surface waters and for waste water treatment.