Intractable Epilepsy

Author : John Oxbury,C. E. Polkey,Michael Duchowny
Publisher : Bailliere Tindall Limited
Page : 0 pages
File Size : 46,6 Mb
Release : 2000
Category : Epilepsy
ISBN : 0702024287

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Intractable Focal Epilepsy by John Oxbury,C. E. Polkey,Michael Duchowny Pdf

Intractable Focal Epilepsyis a definitive multi author reference work covering the most difficult to treat epilepsies. The natural history, pathology and treatment, both medical and surgical, of the conditions underlying intractable seizures are fully described and illustrated. Including contributions from North America, Europe and the Pacific Rim, the emphasis throughout is on clinical diagnosis and treatment both medical and surgical, and their respective outcomes. The text is enhanced by over 250 illustrations, and the clear modern design enables the reader to assimilate information quickly. In addition to clinical treatment, there is a section on the costs of persistent intractable focal epilepsy and the costs of surgical treatment. Drs Oxbury, Polkey and Duchowny have produced a book that will appeal to epileptologists, paediatric neurologists, and neurosurgeons. The books clinical strengths will make it an invaluable working tool. Definitive resource on difficult to treat epilepsies Covers manifestation, consequences and treatment Major section on surgical treatment of focal epilepsy Complete coverage of paediatric diagnosis and treatment Special "Case Reports" give practical case histories to illustrate clinical points International line up of contributors

Author : Jeffrey L. Noebels,Massimo Avoli
Publisher : OUP USA
Page : 1258 pages
File Size : 54,7 Mb
Release : 2012-06-29
Category : Medical
ISBN : 9780199746545

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Jasper's Basic Mechanisms of the Epilepsies by Jeffrey L. Noebels,Massimo Avoli Pdf

Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Author : W. McIntyre Burnham,Peter L. Carlen,Paul A. Hwang
Publisher : Springer Science & Business Media
Page : 252 pages
File Size : 55,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461513353

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Intractable Seizures by W. McIntyre Burnham,Peter L. Carlen,Paul A. Hwang Pdf

About 20% of people with epilepsy have seizures which are resistant to anticonvulsant medications. These drug-resistant seizures are called `intractable', and the patients who have them - about 1 in 500 of the general population - present a major challenge to neurologists and epilepsy associations. The present volume describes the symptomatology of the major `intractable' syndromes, the most appropriate drugs for each, and the possibilities for surgical control. Research related to the causes and effects of unchecked seizures is presented, and new directions in prevention and therapy are discussed.

Author : Luisa Rocha,Esper A. Cavalheiro
Publisher : Springer Science & Business Media
Page : 333 pages
File Size : 48,5 Mb
Release : 2014-07-08
Category : Medical
ISBN : 9781461464648

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Pharmacoresistance in Epilepsy by Luisa Rocha,Esper A. Cavalheiro Pdf

Although more than 10 new antiepileptic drugs have been developed in the past decade, epilepsy remains resistant to drug therapy in about one third of patients, many of whom struggle with the disease their entire lives. Managing these patients is a challenge and requires a structured multidisciplinary approach. The book includes chapters on all issues related to pharmacoresistance in epilepsy and describes recent developments in the pathogenesis and treatment of this disorder. It addresses abnormalities in inhibitory mechanisms, epilepsy-related changes to the immune system, development of pharmacoresistance caused by chronic exposure to antiepileptic drugs, and novel therapeutic strategies for preventing or slowing down the progression of the disease. Clinicians and basic scientists alike will find up-to-date information on the development of pharmacoesistance, as well as reviews of mechanisms associated with epilepsy that may help them consider novel strategies for preventing the development of pharmacoresistance in the first place. The book also features information on new therapeutic strategies for control of epilepsy, such as transcutaneous electrical stimulation and virtual screening of new antiepileptic drugs. Pharmacoresistance in Epilepsy: From Genes and Molecules to Promising Therapies is useful to anyone working in the field, whether they’re studying epilepsy in the lab or treating it in a doctor’s office.”

Author : Dieter Schmidt (M.D.),Paolo Lucio Morselli
Publisher : Lippincott Williams & Wilkins
Page : 298 pages
File Size : 54,5 Mb
Release : 1986
Category : Medical
ISBN : UOM:39015011644153

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Intractable Epilepsy by Dieter Schmidt (M.D.),Paolo Lucio Morselli Pdf

Author : Chrysostomos P. Panayiotopoulos
Publisher : Springer
Page : 570 pages
File Size : 40,5 Mb
Release : 2005
Category : Medical
ISBN : UOM:39015062497741

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The Epilepsies by Chrysostomos P. Panayiotopoulos Pdf

This book gives an exhaustive account of the classification and management of epileptic disorders. It provides clear didactic guidance on the diagnosis and treatment of epileptic syndromes and seizures through thirteen chapters, complemented by a pharmacopoeia and CD ROM of video-EEGs.

Author : Warren W. Boling
Publisher : MDPI
Page : 136 pages
File Size : 52,8 Mb
Release : 2019-01-09
Category : Biology (General)
ISBN : 9783038974499

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Diagnosis and Surgical Treatment of Epilepsy by Warren W. Boling Pdf

This book is a printed edition of the Special Issue "Diagnosis and Surgical Treatment of Epilepsy" that was published in Brain Sciences

Author : Steven C. Schachter,Donald L. Schomer
Publisher : Elsevier
Page : 268 pages
File Size : 43,6 Mb
Release : 1997-05-22
Category : Medical
ISBN : 0080529461

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The Comprehensive Evaluation and Treatment of Epilepsy by Steven C. Schachter,Donald L. Schomer Pdf

Epilepsy is, after headache, the second most common neurological disorder. This book clarifies the many courses of action to take in treating patients with epilepsy. It presents current knowledge about seizures and epilepsy in a comprehensive, socially conscious, and clear manner. The editors have provided this information in a comprehensive, easy-to-use, and practical form. This short, simple pedagogical guide to the diagnosis and management of epilepsy is an important reference work for all medical schools, hospitals, clinics, and primary care centers. This book integrates the latest research into essential reviews on: Initial management of patients with seizures Neuroradiological evaluation of epilepsy Psychosocial aspects of epilepsy Neuropsychologic problems associated with epilepsy Psychiatric disorders Diagnosis and treatment of status epilepticus Nonepileptic seizures Ambulatory EEG monitoring Epilepsy surgery Endocrine aspects of partial seizures Epilepsy in the elderly

Author : Herbert B. Newton,Marta Maschio
Publisher : Elsevier
Page : 292 pages
File Size : 50,5 Mb
Release : 2015-03-06
Category : Medical
ISBN : 9780124171268

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Epilepsy and Brain Tumors by Herbert B. Newton,Marta Maschio Pdf

Patients with brain tumor-related epilepsy (BTRE) suffer from two serious pathologies simultaneously – a brain tumor and a secondary form of epilepsy. Although there has been remarkable progress in BTRE research in recent years, it remains an on-going challenge for clinicians and continues to stimulate much debate in the scientific community. This volume is the first to be completely dedicated to BTRE, and in doing so it explores issues faced by the health care team as well as some of the novel and promising directions that future research may take. Epilepsy and Brain Tumors is not only a complete reference on BTRE but also a practical guide based on clinical experiences, with a comprehensive collection of presentations from international experts who share some of the latest discoveries and their approaches to tackling a wide range of difficult and complex issues. Includes coverage of epidemiology, pathology and treatment of both primary and metastatic brain tumors Offers additional insight into supportive care, incidence in children, focal epileptogenesis, clinical evaluation, antiepileptic drugs, surgical treatment, cognitive rehabilitation, and more Chapters authored and edited by leaders in the field around the globe – the broadest, most expert coverage available

Author : Gregory D. Cascino,Joseph I. Sirven,William O. Tatum
Publisher : John Wiley & Sons
Page : 550 pages
File Size : 48,5 Mb
Release : 2021-08-02
Category : Medical
ISBN : 9781119431824

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Epilepsy by Gregory D. Cascino,Joseph I. Sirven,William O. Tatum Pdf

Designed to provide a comprehensive but accessible introduction to epilepsy and seizure disorders, Epilepsy, 2nd edition provides state-of-the-art information in a concise format useful to a wide audience, from neurology residents to epilepsy fellows and practitioners. This illustrated guide to the assessment, diagnosis, and treatment of epilepsy is a valuable resource enabling clinicians to stay on top of the latest recommendations for best practice.

Author : Ruben Kuzniecky,Graeme D. Jackson
Publisher : Academic Press
Page : 464 pages
File Size : 43,8 Mb
Release : 2005-01-19
Category : Medical
ISBN : 0080535712

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Magnetic Resonance in Epilepsy by Ruben Kuzniecky,Graeme D. Jackson Pdf

Remarkable advances in imaging have increased the importance of MRI for diagnostic, treatment and management of epilepsy. Neuroimaging of patients with epilepsy no longer simply deals with the technology and interpretation of images but also with issues of brain metabolism, energetics, cognition and brain dysfunction. The first edition of Magnetic Resonance in Epilepsy came into clinical practice in 1995 with a revolutionary idea; that is, MR is as important as EEG in the clinical management of patients with epilepsy. The second edition of Magnetic Resonance in Epilepsy, the only comprehensive text in the field of epilepsy neuroimaging, reviews fundamental concepts and new advances in MR technology, computerized analysis, MR spectroscopy, DWI and other neuroimaging techniques such as PET, SPECT and MEG application to the study of patients with epileptic disorders. *Provides a crucial update of recent advances in imaging techniques *Timely publication as subject of neuroimaging is a very "hot" area in both clinical epilepsy and basic neuroscience research *Editors are well-respected in this field

Author : Konstantinos Fountas,Eftychia Z. Kapsalaki
Publisher : Springer
Page : 301 pages
File Size : 46,5 Mb
Release : 2018-10-03
Category : Medical
ISBN : 9783319959184

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Epilepsy Surgery and Intrinsic Brain Tumor Surgery by Konstantinos Fountas,Eftychia Z. Kapsalaki Pdf

This book provides a comprehensive and practical guide for the safe and efficient management of patients with intrinsic brain tumors and medically intractable epilepsy. It presents in an easily understandable way the preoperative evaluation of these patients, starting from the clinical interpretation of conventional anatomical MR imaging and analyses the clinical significance of newer MR based imaging techniques such as diffusion and perfusion imaging. It demonstrates with clarity the role of MR spectroscopy and fractional anisotropy and diffusion tensor imaging in the preoperative assessment of these patients and how this data can be incorporated into the surgical planning. This book is aimed at neurosurgeons, neuroradiologists, neurologists, and epileptologists, and may also be of interest to neuropsychologists, neurophysiologists, radiation oncologists, and medical physicists.

Author : John Milton,Peter Jung
Publisher : Springer Science & Business Media
Page : 439 pages
File Size : 47,7 Mb
Release : 2013-04-17
Category : Science
ISBN : 9783662050484

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Epilepsy as a Dynamic Disease by John Milton,Peter Jung Pdf

The first book to bring together experts in epilepsy, bio-engineering and dynamical systems theory, to discuss the possibility of treating epilepsy by controlling mechanisms that cause seizures. It includes a unique reference database with more than 1000 references, including hard-to-access references in the Russian literature.

Author : Gordon H. Baltuch,Arthur Cukiert
Publisher : Thieme
Page : 598 pages
File Size : 50,7 Mb
Release : 2019-11-07
Category : Medical
ISBN : 9781626238190

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Operative Techniques in Epilepsy Surgery by Gordon H. Baltuch,Arthur Cukiert Pdf

An indispensable, single-volume resource on state-of-the-art epilepsy procedures from renowned international experts! Epilepsy is a common neurological disorder affecting an estimated 1% of the population, about 20 to 30% of which experience seizures inadequately controlled by medical therapy alone. Advances in anatomic and functional imaging modalities, stereotaxy, and the integration of neuronavigation during surgery have led to cutting-edge treatment options for patients with medically refractory epilepsy. Operative Techniques in Epilepsy Surgery, Second Edition by Gordon Baltuch, Arthur Cukiert, and an impressive international group of contributors has been updated and expanded, reflecting the newest treatments for pediatric and adult epilepsy. Seven sections with 30 chapters encompass surgical planning, invasive EEG studies, cortical resection, intraoperative mapping, disconnection, neuromodulation, and further topics. Twelve cortical resection chapters cover surgical approaches such as amygdalohippocampectomy; hippocampal transection; frontal lobe, central region, and posterior quadrant resections; and microsurgery versus endoscopy for hypothalamic hamartomas. Disconnection procedures discussed in section five include corpus callosotomy, hemispherectomy, and endoscopic-assisted approaches. Well-established procedures such as vagus nerve and deep brain stimulation are covered in the neuromodulation section, while the last section discusses radiosurgery for medically intractable cases. Key Highlights Chapters new to this edition include endoscopic callosotomy, laser-induced thermal therapy (LITT), and focused ultrasound High-quality illustrations, superb operative and cadaver photographs, radiologic images, and tables enhance understanding of impacted anatomy and specific techniques The addition of videos provides insightful step-by-step procedural guidance This is an essential reference for fellows and residents interested in epilepsy and functional neurosurgery, and an ideal overview for neurosurgeons, neurologists, and neuroradiologists in early career stages who wish to pursue this subspecialty.

Author : Heinz Gregor Wieser,Dominik Zumsteg
Publisher : John Libbey Eurotext
Page : 208 pages
File Size : 45,9 Mb
Release : 2008-02-01
Category : Medical
ISBN : 9782742009664

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Subthalamic and Thalamic Stereotactic Recordings and Stimulations in Patients with Intractable Epilepsy by Heinz Gregor Wieser,Dominik Zumsteg Pdf

Various subcortical structures in the brain are thought to be important in genesis or propagation of seizures. Deep Brain Stimulation (DBS) of these structures aims to influence these key “pacemaker” areas in the brain and is gaining increasing interest as a possible new surgical modality for treatment of patients with intractable epilepsy. Based on this background, this volume brings together the experience of the Zurich Epilepsy Surgery Center with stereotactic recordings and stimulations of various subcortical nuclei, with special reference to the Forel H fields, the thalamic nuclei and the periaqueductal gray matter. This volume also addresses the important issues of DC recording/polarisation and of biochemical measurement of excitatory and inhibitory transmitters released in the primary epileptogenic area during epileptic discharges. This book is destined to improve understanding of the involvement of subcortical structures in seizure genesis or propagation in a time when exhaustive invasive presurgical evaluation is diminishing because of the today’s availability of modern non-invasive imaging technique.