Introduction To Biophysical Methods For Protein And Nucleic Acid Research

Author : Jay A. Glasel,Murray P. Deutscher
Publisher : Academic Press
Page : 510 pages
File Size : 48,9 Mb
Release : 1995-11-20
Category : Science
ISBN : 0080534988

Get Book

Introduction to Biophysical Methods for Protein and Nucleic Acid Research by Jay A. Glasel,Murray P. Deutscher Pdf

The first of its kind, Introduction to Biophysical Methods for Protein and Nucleic Acid Research serves as a text for the experienced researcher and student requiring an introduction to the field. Each chapter presents a description of the physical basis of the method, the type of information that may be obtained with the method, how data should be analyzed and interpreted and, where appropriate, practical tips about procedures and equipment. Key Features * Modern Use of Mass Spectroscopy * NMR Spectroscopy * Molecular Modeling and Graphics * Macintosh and DOS/Windows 3.x disks

Author : Lev Abramovich Osterman
Publisher : Springer
Page : 528 pages
File Size : 45,8 Mb
Release : 1984
Category : Science
ISBN : UOM:39015012556976

Get Book

Methods of Protein and Nucleic Acid Research by Lev Abramovich Osterman Pdf

Author : Lev Abramovič Osterman
Publisher : Unknown
Page : 128 pages
File Size : 55,7 Mb
Release : 1984
Category : Electronic
ISBN : OCLC:834698410

Get Book

Methods of protein and nucleic acid research by Lev Abramovič Osterman Pdf

Author : Jay L. Nadeau
Publisher : CRC Press
Page : 1223 pages
File Size : 40,5 Mb
Release : 2017-10-10
Category : Medical
ISBN : 9781351000925

Get Book

Introduction to Experimental Biophysics by Jay L. Nadeau Pdf

Praise for the First Edition “essential reading for any physical scientist who is interested in performing biological research.” ―Contemporary Physics "an ambitious text.... Each chapter contains protocols and the conceptual reasoning behind them, which is often useful to physicists performing biological experiments for the first time." –Physics Today This fully updated and expanded text is the best starting point for any student or researcher in the physical sciences to gain firm grounding in the techniques employed in molecular biophysics and quantitative biology. It includes brand new chapters on gene expression techniques, advanced techniques in biological light microscopy (super-resolution, two-photon, and fluorescence lifetime imaging), holography, and gold nanoparticles used in medicine. The author shares invaluable practical tips and insider’s knowledge to simplify potentially confusing techniques. The reader is guided through easy-to-follow examples carried out from start to finish with practical tips and insider’s knowledge. The emphasis is on building comfort with getting hands "wet" with basic methods and finally understanding when and how to apply or adapt them to address different questions. Jay L. Nadeau is a scientific researcher and head of the Biomedical Engineering in Advanced Applications of Quantum, Oscillatory, and Nanotechnological Systems (BEAAQONS) lab at Caltech and was previously associate professor of biomedical engineering and physics at McGill University.

Author : Lev Abramovich Osterman
Publisher : Unknown
Page : 128 pages
File Size : 49,6 Mb
Release : 1984
Category : Centrifugation
ISBN : LCCN:83016864

Get Book

Methods of Protein and Nucleic Acid Research: Electrophoresis, isoelectric focusing, ultracentrifugation by Lev Abramovich Osterman Pdf

Author : Harald Tschesche
Publisher : Unknown
Page : 464 pages
File Size : 40,7 Mb
Release : 1990
Category : Nucleic acids
ISBN : UOM:39015019420523

Get Book

Modern Methods in Protein- and Nucleic Acid Research by Harald Tschesche Pdf

Author : Peter E. Nielsen
Publisher : Springer Science & Business Media
Page : 270 pages
File Size : 54,7 Mb
Release : 2008-02-04
Category : Science
ISBN : 9781592592906

Get Book

Peptide Nucleic Acids by Peter E. Nielsen Pdf

Peptide nucleic acids (PNAs) have now existed for slightly more than ten years, with the interest in and applications of this pseudopeptide DNA mimic steadily increasing during the entire period. PNAs have rapidly attracted the attention of scientists from a diversity of fields ranging from (bio)organic and biophysical chemistry to prebiotic evolution, and from molecular biology to genetic diagnostics and drug development. Many of the applications take advantage of the unique properties of PNA—an uncharged pseudopeptide—that distinguish this DNA mimic from more traditional DNA analogs. Rather than trying to create a comprehensive collection of all published methods and protocols involving PNA—many of which have not yet been validated— I have decided to concentrate on select protocols that are either very well established by several groups around the world, such as PCR-clamping and in situ hybridization, or on new methods that may have broader future impact. Basic methods for PNA oligomer synthesis and analyses have also been included. I am very grateful to those friends and colleagues who have enthusiastically contributed their work, discussions, and writing, and thereby made this book possible. Peter E. Nielsen v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix IINTRODUCTION 1 PNA Technology Peter E. Nielsen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 II CHEMISTRY 2 Solid Phase Synthesis of PNA Oligomers Frederik Beck. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 3 Synthesis of PNA-Peptide Conjugates Satish Kumar Awasthi and Peter E. Nielsen. . . . . . . . . . . . . . . . . . 43 4 Parallel Synthesis of PNA-Peptide Conjugate Libraries Satish Kumar Awasthi and Peter E. Nielsen. . . . . . . . . . . . . . . . . .

Author : Tung-Bin Lo,Teh-Yung Liu,Choh Hao Li,Choh-Hao Li
Publisher : Elsevier Publishing Company
Page : 464 pages
File Size : 47,6 Mb
Release : 1984
Category : Biochemistry
ISBN : UCAL:B4492528

Get Book

Biochemical and Biophysical Studies of Proteins and Nucleic Acids by Tung-Bin Lo,Teh-Yung Liu,Choh Hao Li,Choh-Hao Li Pdf

Author : Lev Abramovich Osterman
Publisher : Unknown
Page : 128 pages
File Size : 43,5 Mb
Release : 1984
Category : Centrifugation
ISBN : 0387127356

Get Book

Methods of Protein and Nucleic Acid Research: Chromatography by Lev Abramovich Osterman Pdf

Author : Lev A. Osterman
Publisher : Unknown
Page : 505 pages
File Size : 42,8 Mb
Release : 1986
Category : Electronic
ISBN : OCLC:632528800

Get Book

Methods of Protein and Nucleic Acid Research by Lev A. Osterman Pdf

Author : Gauri Misra
Publisher : Springer
Page : 274 pages
File Size : 40,8 Mb
Release : 2017-09-07
Category : Medical
ISBN : 9789811049682

Get Book

Introduction to Biomolecular Structure and Biophysics by Gauri Misra Pdf

This comprehensive book presents a modern concept in biophysics based on recently published research. It highlights various aspects of the biophysical fundamentals and techniques that are currently used to study different physical properties of biomolecules, and relates the biological phenomenon with the underlying physical concepts. The content is divided into nine chapters summarizing the structural details of proteins, including recently discovered novel folds, higher order structures of nucleic acids, as well as lipids and the physical forces governing the macromolecular interactions which are essential for the various biological processes. It also provides insights into the recent advances in biophysical techniques including Hydrogen Deuterium Exchange with Mass Spectrometry (HDX-MS), Small angle X-ray scattering (SAXS) and Cryo Electron Microscopy (cryo EM), supplemented with interesting experimental data. It is a valuable reference resource for anyone with a desire to gain a better understanding of the fundamentals of biophysical concepts and techniques of important biomolecules.

Author : Jay Nadeau
Publisher : CRC Press
Page : 674 pages
File Size : 42,6 Mb
Release : 2011-09-21
Category : Science
ISBN : 9781439829530

Get Book

Introduction to Experimental Biophysics by Jay Nadeau Pdf

Increasing numbers of physicists, chemists, and mathematicians are moving into biology, reading literature across disciplines, and mastering novel biochemical concepts. To succeed in this transition, researchers must understand on a practical level what is experimentally feasible. The number of experimental techniques in biology is vast and often specific to particular subject areas; nonetheless, there are a few basic methods that provide a conceptual underpinning for broad application. Introduction to Experimental Biophysics is the ideal benchtop companion for physical scientists interested in getting their hands wet. Assuming familiarity with basic physics and the scientific method but no previous background in biology or chemistry, this book provides: A thorough description of modern experimental and analytical techniques used in biological and biophysical research Practical information and step-by-step guidance on instrumentation and experimental design Recipes for common solutions and media, lists of important reagents, and a glossary of biological terms used Developed for graduate students in biomedical engineering, physics, chemical engineering, chemistry, mathematics, and computer science, Introduction to Experimental Biophysics is an essential resource for scientists to overcoming conceptual and technical barriers to working in a biology wet lab.

Author : Igor N. Serdyuk,Nathan R. Zaccai,Joseph Zaccai
Publisher : Cambridge University Press
Page : 1137 pages
File Size : 50,6 Mb
Release : 2007-03-29
Category : Science
ISBN : 9781139461580

Get Book

Methods in Molecular Biophysics by Igor N. Serdyuk,Nathan R. Zaccai,Joseph Zaccai Pdf

Our knowledge of biological macromolecules and their interactions is based on the application of physical methods, ranging from classical thermodynamics to recently developed techniques for the detection and manipulation of single molecules. These methods, which include mass spectrometry, hydrodynamics, microscopy, diffraction and crystallography, electron microscopy, molecular dynamics simulations, and nuclear magnetic resonance, are complementary; each has its specific advantages and limitations. Organised by method, this textbook provides descriptions and examples of applications for the key physical methods in modern biology. It is an invaluable resource for undergraduate and graduate students of molecular biophysics in science and medical schools, as well as research scientists looking for an introduction to techniques beyond their specialty. As appropriate for this interdisciplinary field, the book includes short asides to explain physics aspects to biologists and biology aspects to physicists.

Author : L.A. Osterman
Publisher : Springer
Page : 206 pages
File Size : 53,6 Mb
Release : 1984-02-01
Category : Science
ISBN : 3540130942

Get Book

Methods of Protein and Nucleic Acid Research by L.A. Osterman Pdf

Author : Igor N. Serdyuk,Nathan R. Zaccai,Joseph Zaccai,Giuseppe Zaccai
Publisher : Cambridge University Press
Page : 709 pages
File Size : 55,5 Mb
Release : 2017-05-18
Category : Medical
ISBN : 9781107056374

Get Book

Methods in Molecular Biophysics by Igor N. Serdyuk,Nathan R. Zaccai,Joseph Zaccai,Giuseppe Zaccai Pdf

A comprehensive graduate textbook explaining key physical methods in biology, reflecting the very latest research in this fast-moving field.