Introduction To Evolutionary Genomics

Author : Naruya Saitou
Publisher : Springer
Page : 504 pages
File Size : 55,7 Mb
Release : 2018-10-25
Category : Computers
ISBN : 9783319926421

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Introduction to Evolutionary Genomics by Naruya Saitou Pdf

This authoritative textbook/reference presents a comprehensive introduction to the field of evolutionary genomics. The opening chapters describe the fundamental concepts in molecular biology and genome evolution for readers without any prior background in this area. This is followed by a detailed examination of genome evolution in various different groups of organisms. The text then concludes with a review of practical methods essential to researchers in the field. This updated and revised new edition also features historical perspectives on contributions to evolutionary genomics from related fields such as molecular evolution, genetics, and numerical taxonomy. Topics and features: introduces the basics of molecular biology, covering protein structure and diversity, as well as DNA replication, transcription, and translation; examines the phylogenetic relationships of DNA sequences, and the processes of mutation, neutral evolution, and natural selection; presents a brief evolutionary history of life, surveying the key features of the genomes of prokaryotes, eukaryotes, viruses and phages, vertebrates, and humans; reviews the various biological “omic” databases, and discusses the analysis of homologous nucleotide and amino acid sequences; provides an overview of the experimental sequencing of genomes and transcriptomes, and the construction of phylogenetic trees; describes methods for estimating of evolutionary distances, and performing studies of population genetics; supplies additional supporting material at an associated website. Serving as an indispensable textbook for graduate and advanced undergraduate courses on evolutionary genomics, this accessible overview will also prove invaluable to researchers from both computer science and the biological sciences seeking a primer on the field.

Author : Naruya Saitou
Publisher : Springer Science & Business Media
Page : 461 pages
File Size : 42,9 Mb
Release : 2014-01-22
Category : Computers
ISBN : 9781447153047

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Introduction to Evolutionary Genomics by Naruya Saitou Pdf

This book is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for readers unfamiliar with evolutionary studies. Features: introduces the basics of molecular biology, DNA replication, mutation, phylogeny, neutral evolution, and natural selection; presents a brief evolutionary history of life from the primordial seas to the emergence of humans; describes the genomes of prokaryotes, eukaryotes, vertebrates, and humans; reviews methods for genome sequencing, phenotype data collection, homology searches and analysis, and phylogenetic tree and network building; discusses databases of genome sequences and related information, evolutionary distances, and population genomics; provides supplementary material at an associated website.

Author : Glenn-Peter Sætre,Mark Ravinet
Publisher : Oxford University Press, USA
Page : 327 pages
File Size : 41,9 Mb
Release : 2019-05
Category : Science
ISBN : 9780198830917

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Evolutionary Genetics by Glenn-Peter Sætre,Mark Ravinet Pdf

Evolutionary genetics is the study of how genetic variation leads to evolutionary change. With the recent explosion in the availability of whole genome sequence data, vast quantities of genetic data are being generated at an ever-increasing pace with the result that programming has become an essential tool for researchers. Most importantly, a thorough understanding of evolutionary principles is essential for making sense of this genetic data. This up-to-date textbook covers all the major components of modern evolutionary genetics, carefully explaining fundamental processes such as mutation, natural selection, genetic drift, and speciation, together with their consequences. The book also draws on a rich literature of exciting and inspiring examples to demonstrate the diversity of evolutionary research, including an emphasis on how evolution and selection has shaped our own species. Furthermore, at the end of each chapter, study questions are provided to motivate the reader to think and reflect on the concepts introduced. Practical experience is essential when it comes to developing an understanding of how to use genetic and genomic data to analyze and address interesting questions in the life sciences and how to interpret results in meaningful ways. In addition to the main text, a series of online tutorials using the R language serves as an introduction to programming, statistics, and the analysis of evolutionary genetic data. The R environment stands out as an ideal all-purpose, open source platform to handle and analyze such data. The book and its online materials take full advantage of the authors' own experience in working in a post-genomic revolution world, and introduce readers to the plethora of molecular and analytical methods that have only recently become available.

Author : Maria Anisimova
Publisher : Humana Press
Page : 484 pages
File Size : 43,5 Mb
Release : 2016-05-01
Category : Medical
ISBN : 1493959085

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Evolutionary Genomics by Maria Anisimova Pdf

This book examines developments in statistical methodology and the challenges that followed rapidly improving sequencing technologies.Includes articles encompassing theoretical works and hands-on tutorials, as well as many reviews with key biological insight."

Author : Eugene V. Koonin,Michael Galperin
Publisher : Springer Science & Business Media
Page : 482 pages
File Size : 48,7 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781475737837

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Sequence — Evolution — Function by Eugene V. Koonin,Michael Galperin Pdf

Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.

Author : David T. Parkin
Publisher : Unknown
Page : 240 pages
File Size : 50,6 Mb
Release : 1979
Category : Science
ISBN : UOM:39015005794352

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An Introduction to Evolutionary Genetics by David T. Parkin Pdf

Author : A.E. Eiben,J.E. Smith
Publisher : Springer Science & Business Media
Page : 328 pages
File Size : 46,8 Mb
Release : 2007-08-06
Category : Computers
ISBN : 3540401849

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Introduction to Evolutionary Computing by A.E. Eiben,J.E. Smith Pdf

The first complete overview of evolutionary computing, the collective name for a range of problem-solving techniques based on principles of biological evolution, such as natural selection and genetic inheritance. The text is aimed directly at lecturers and graduate and undergraduate students. It is also meant for those who wish to apply evolutionary computing to a particular problem or within a given application area. The book contains quick-reference information on the current state-of-the-art in a wide range of related topics, so it is of interest not just to evolutionary computing specialists but to researchers working in other fields.

Author : Christoph Bleidorn
Publisher : Springer
Page : 222 pages
File Size : 52,6 Mb
Release : 2017-06-01
Category : Science
ISBN : 9783319540641

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Phylogenomics by Christoph Bleidorn Pdf

This unique textbook provides a clear and concise overview of the key principles of the complex field of phylogenomics, with a particular focus on sequencing technologies that are crucial to studying and understanding interrelations in evolutionary genomics. It includes chapters dedicated to the analysis of nucleotide sequences using assembling and alignment methods and also discusses the main strategies for phylogenetic studies, systematic errors and their correction. This highly readable textbook is intended for graduate students and young researchers with an interest in phylogenetics and evolutionary developmental biology.

Author : Agoston E. Eiben,J.E. Smith
Publisher : Springer Science & Business Media
Page : 307 pages
File Size : 42,7 Mb
Release : 2013-03-14
Category : Computers
ISBN : 9783662050941

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Introduction to Evolutionary Computing by Agoston E. Eiben,J.E. Smith Pdf

The first complete overview of evolutionary computing, the collective name for a range of problem-solving techniques based on principles of biological evolution, such as natural selection and genetic inheritance. The text is aimed directly at lecturers and graduate and undergraduate students. It is also meant for those who wish to apply evolutionary computing to a particular problem or within a given application area. The book contains quick-reference information on the current state-of-the-art in a wide range of related topics, so it is of interest not just to evolutionary computing specialists but to researchers working in other fields.

Author : Mark Jobling,Edward Hollox,Toomas Kivisild,Chris Tyler-Smith
Publisher : Garland Science
Page : 1557 pages
File Size : 49,5 Mb
Release : 2013-06-25
Category : Medical
ISBN : 9781317952251

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Human Evolutionary Genetics by Mark Jobling,Edward Hollox,Toomas Kivisild,Chris Tyler-Smith Pdf

Human Evolutionary Genetics is a groundbreaking text which for the first time brings together molecular genetics and genomics to the study of the origins and movements of human populations. Starting with an overview of molecular genomics for the non-specialist (which can be a useful review for those with a more genetic background), the book shows h

Author : Robert H. S. Kraus
Publisher : Springer
Page : 348 pages
File Size : 50,7 Mb
Release : 2019-06-29
Category : Science
ISBN : 9783030164775

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Avian Genomics in Ecology and Evolution by Robert H. S. Kraus Pdf

Birds catch the public imagination like no other group of animals; in addition, birders are perhaps the largest non-professional naturalist community. Genomics and associated bioinformatics have revolutionised daily life in just a few decades. At the same time, this development has facilitated the application of genomics technology to ecological and evolutionary studies, including biodiversity and conservation at all levels. This book reveals how the exciting toolbox of genomics offers new opportunities in all areas of avian biology. It presents contributions from prominent experts at the intersection of avian biology and genomics, and offers an ideal introduction to the world of genomics for students, biologists and bird enthusiasts alike. The book begins with a historical perspective on how genomic technology was adopted by bird ecology and evolution research groups. This led, as the book explains, to a revised understanding of avian evolution, with exciting consequences for biodiversity research as a whole. Lastly, these impacts are illustrated using seminal examples and the latest discoveries from avian biology laboratories around the world.

Author : Glenn-Peter Sætre,Mark Ravinet
Publisher : Oxford University Press
Page : 352 pages
File Size : 54,5 Mb
Release : 2019-05-13
Category : Science
ISBN : 9780192566652

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Evolutionary Genetics by Glenn-Peter Sætre,Mark Ravinet Pdf

With recent technological advances, vast quantities of genetic and genomic data are being generated at an ever-increasing pace. The explosion in access to data has transformed the field of evolutionary genetics. A thorough understanding of evolutionary principles is essential for making sense of this, but new skill sets are also needed to handle and analyze big data. This contemporary textbook covers all the major components of modern evolutionary genetics, carefully explaining fundamental processes such as mutation, natural selection, genetic drift, and speciation. It also draws on a rich literature of exciting and inspiring examples to demonstrate the diversity of evolutionary research, including an emphasis on how evolution and selection has shaped our own species. Practical experience is essential for developing an understanding of how to use genetic and genomic data to analyze and interpret results in meaningful ways. In addition to the main text, a series of online tutorials using the R language serves as an introduction to programming, statistics, and analysis. Indeed the R environment stands out as an ideal all-purpose source platform to handle and analyze such data. The book and its online materials take full advantage of the authors' own experience in working in a post-genomic revolution world, and introduces readers to the plethora of molecular and analytical methods that have only recently become available. Evolutionary Genetics is an advanced but accessible textbook aimed principally at students of various levels (from undergraduate to postgraduate) but also for researchers looking for an updated introduction to modern evolutionary biology and genetics.

Author : Mark D. Pagel,Andrew Pomiankowski
Publisher : Sinauer Associates, Incorporated
Page : 372 pages
File Size : 53,9 Mb
Release : 2008
Category : Science
ISBN : UOM:39015074251078

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Evolutionary Genomics and Proteomics by Mark D. Pagel,Andrew Pomiankowski Pdf

Highlights new research on developments in the rapidly advancing areas of genomics and proteomics, with particular emphasis on placing these fields in an evolutionary context. Topics incude systems biology, the origin of genes and lateral gene transfer, gene regulation and gene dispensability, proteome complexity, genomic immune systems, sex-biased genomic expression, sex chromosome evolution, gene and protein network evolution, adaptive genome evolution, and human evolutional genomics.

Author : Brian Charlesworth,Deborah Charlesworth
Publisher : Roberts
Page : 776 pages
File Size : 41,8 Mb
Release : 2010-02-03
Category : Science
ISBN : STANFORD:36105215340113

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Elements of Evolutionary Genetics by Brian Charlesworth,Deborah Charlesworth Pdf

This textbook shows readers how models of the genetic processes involved in evolution are made (including natural selection, migration, mutation, and genetic drift in finite populations), and how the models are used to interpret classical and molecular genetic data. The material is intended for advanced level undergraduate courses in genetics and evolutionary biology, graduate students in evolutionary biology and human genetics, and researchers in related fields who wish to learn evolutionary genetics. The topics covered include genetic variation, DNA sequence variability and its measurement, the different types of natural selection and their effects (e.g. the maintenance of variation, directional selection, and adaptation), the interactions between selection and mutation or migration, the description and analysis of variation at multiple sites in the genome, genetic drift, and the effects of spatial structure.

Author : Bernhard Haubold,Thomas Wiehe
Publisher : Springer Science & Business Media
Page : 328 pages
File Size : 42,8 Mb
Release : 2006-08-09
Category : Science
ISBN : 9783764373870

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Introduction to Computational Biology by Bernhard Haubold,Thomas Wiehe Pdf

Written with the advanced undergraduate in mind, this book introduces into the field of Bioinformatics. The authors explain the computational and conceptional background to the analysis of large-scale sequence data. Many of the corresponding analysis methods are rooted in evolutionary thinking, which serves as a common thread throughout the book. The focus is on methods of comparative genomics and subjects covered include: alignments, gene finding, phylogeny, and the analysis of single nucleotide polymorphisms (SNPs). The volume contains exercises, questions & answers to selected problems.