Evolutionary Genomics

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Introduction to Evolutionary Genomics

Naruya Saitou
Introduction to Evolutionary Genomics Book PDF

Author : Naruya Saitou
Publisher : Springer Science & Business Media
Page : 461 pages
File Size : 54,5 Mb
Release : 2014-01-22
Category : Computers
ISBN : 9781447153047

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Introduction to Evolutionary Genomics by Naruya Saitou Pdf

This book is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for readers unfamiliar with evolutionary studies. Features: introduces the basics of molecular biology, DNA replication, mutation, phylogeny, neutral evolution, and natural selection; presents a brief evolutionary history of life from the primordial seas to the emergence of humans; describes the genomes of prokaryotes, eukaryotes, vertebrates, and humans; reviews methods for genome sequencing, phenotype data collection, homology searches and analysis, and phylogenetic tree and network building; discusses databases of genome sequences and related information, evolutionary distances, and population genomics; provides supplementary material at an associated website.

Evolutionary Genomics

Maria Anisimova
Evolutionary Genomics Book PDF

Author : Maria Anisimova
Publisher : Humana Press
Page : 484 pages
File Size : 45,5 Mb
Release : 2016-05-01
Category : Medical
ISBN : 1493959085

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Evolutionary Genomics by Maria Anisimova Pdf

This book examines developments in statistical methodology and the challenges that followed rapidly improving sequencing technologies.Includes articles encompassing theoretical works and hands-on tutorials, as well as many reviews with key biological insight."

Evolutionary Genomics and Proteomics

Mark D. Pagel,Andrew Pomiankowski
Evolutionary Genomics and Proteomics Book PDF

Author : Mark D. Pagel,Andrew Pomiankowski
Publisher : Sinauer Associates, Incorporated
Page : 372 pages
File Size : 42,6 Mb
Release : 2008
Category : Science
ISBN : UOM:39015074251078

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Evolutionary Genomics and Proteomics by Mark D. Pagel,Andrew Pomiankowski Pdf

Highlights new research on developments in the rapidly advancing areas of genomics and proteomics, with particular emphasis on placing these fields in an evolutionary context. Topics incude systems biology, the origin of genes and lateral gene transfer, gene regulation and gene dispensability, proteome complexity, genomic immune systems, sex-biased genomic expression, sex chromosome evolution, gene and protein network evolution, adaptive genome evolution, and human evolutional genomics.

Sequence — Evolution — Function

Eugene V. Koonin,Michael Galperin
Sequence Evolution Function Book PDF

Author : Eugene V. Koonin,Michael Galperin
Publisher : Springer Science & Business Media
Page : 482 pages
File Size : 46,9 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781475737837

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Sequence — Evolution — Function by Eugene V. Koonin,Michael Galperin Pdf

Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.

Ecological Genomics

Christian R. Landry,Nadia Aubin-Horth
Ecological Genomics Book PDF

Author : Christian R. Landry,Nadia Aubin-Horth
Publisher : Springer Science & Business Media
Page : 359 pages
File Size : 55,6 Mb
Release : 2013-11-25
Category : Science
ISBN : 9789400773479

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Ecological Genomics by Christian R. Landry,Nadia Aubin-Horth Pdf

Researchers in the field of ecological genomics aim to determine how a genome or a population of genomes interacts with its environment across ecological and evolutionary timescales. Ecological genomics is trans-disciplinary by nature. Ecologists have turned to genomics to be able to elucidate the mechanistic bases of the biodiversity their research tries to understand. Genomicists have turned to ecology in order to better explain the functional cellular and molecular variation they observed in their model organisms. We provide an advanced-level book that covers this recent research and proposes future development for this field. A synthesis of the field of ecological genomics emerges from this volume. Ecological Genomics covers a wide array of organisms (microbes, plants and animals) in order to be able to identify central concepts that motivate and derive from recent investigations in different branches of the tree of life. Ecological Genomics covers 3 fields of research that have most benefited from the recent technological and conceptual developments in the field of ecological genomics: the study of life-history evolution and its impact of genome architectures; the study of the genomic bases of phenotypic plasticity and the study of the genomic bases of adaptation and speciation.

Evolutionary Genomics

Maria Anisimova
Evolutionary Genomics Book PDF

Author : Maria Anisimova
Publisher : Humana Press
Page : 556 pages
File Size : 49,8 Mb
Release : 2012-03-08
Category : Medical
ISBN : 1617795844

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Evolutionary Genomics by Maria Anisimova Pdf

Together with early theoretical work in population genetics, the debate on sources of genetic makeup initiated by proponents of the neutral theory made a solid contribution to the spectacular growth in statistical methodologies for molecular evolution. Evolutionary Genomics: Statistical and Computational Methods is intended to bring together the more recent developments in the statistical methodology and the challenges that followed as a result of rapidly improving sequencing technologies. Presented by top scientists from a variety of disciplines, the collection includes a wide spectrum of articles encompassing theoretical works and hands-on tutorials, as well as many reviews with key biological insight. Volume 2 begins with phylogenomics and continues with in-depth coverage of natural selection, recombination, and genomic innovation. The remaining chapters treat topics of more recent interest, including population genomics, -omics studies, and computational issues related to the handling of large-scale genomic data. Written in the highly successful Methods in Molecular BiologyTM series format, this work provides the kind of advice on methodology and implementation that is crucial for getting ahead in genomic data analyses. Comprehensive and cutting-edge, Evolutionary Genomics: Statistical and Computational Methods is a treasure chest of state-of the-art methods to study genomic and omics data, certain to inspire both young and experienced readers to join the interdisciplinary field of evolutionary genomics.

Evolutionary Genomics and Systems Biology

Gustavo Caetano-Anollés
Evolutionary Genomics and Systems Biology Book PDF

Author : Gustavo Caetano-Anollés
Publisher : Wiley-Blackwell
Page : 330 pages
File Size : 44,6 Mb
Release : 2010-07-08
Category : Science
ISBN : 9780470570401

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Evolutionary Genomics and Systems Biology by Gustavo Caetano-Anollés Pdf

A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of the protein and RNA machinery that propels life; and the evolutionary and dynamic study of wiring diagrams—macromolecular components in interaction—in the context of genomic complements. The book also features: A solid, comprehensive treatment of phylogenomics, the evolution of genomes, and the evolution of biological networks, within the framework of systems biology A special section on RNA biology—translation, evolution of structure, and micro RNA and regulation of gene expression Chapters on the mapping of genotypes to phenotypes, the role of information in biology, protein architecture and biological function, chromosomal rearrangements, and biological networks and disease Contributions by leading authorities on each topic Evolutionary Genomics and Systems Biology is an ideal book for students and professionals in genomics, bioinformatics, evolution, structural biology, complexity, origins of life, systematic biology, and organismal diversity, as well as those individuals interested in aspects of biological sciences as they interface with chemistry, physics, and computer science and engineering.

Evolutionary Genetics

Glenn-Peter Sætre,Mark Ravinet
Evolutionary Genetics Book PDF

Author : Glenn-Peter Sætre,Mark Ravinet
Publisher : Oxford University Press, USA
Page : 327 pages
File Size : 51,6 Mb
Release : 2019-05
Category : Science
ISBN : 9780198830917

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Evolutionary Genetics by Glenn-Peter Sætre,Mark Ravinet Pdf

Evolutionary genetics is the study of how genetic variation leads to evolutionary change. With the recent explosion in the availability of whole genome sequence data, vast quantities of genetic data are being generated at an ever-increasing pace with the result that programming has become an essential tool for researchers. Most importantly, a thorough understanding of evolutionary principles is essential for making sense of this genetic data. This up-to-date textbook covers all the major components of modern evolutionary genetics, carefully explaining fundamental processes such as mutation, natural selection, genetic drift, and speciation, together with their consequences. The book also draws on a rich literature of exciting and inspiring examples to demonstrate the diversity of evolutionary research, including an emphasis on how evolution and selection has shaped our own species. Furthermore, at the end of each chapter, study questions are provided to motivate the reader to think and reflect on the concepts introduced. Practical experience is essential when it comes to developing an understanding of how to use genetic and genomic data to analyze and address interesting questions in the life sciences and how to interpret results in meaningful ways. In addition to the main text, a series of online tutorials using the R language serves as an introduction to programming, statistics, and the analysis of evolutionary genetic data. The R environment stands out as an ideal all-purpose, open source platform to handle and analyze such data. The book and its online materials take full advantage of the authors' own experience in working in a post-genomic revolution world, and introduce readers to the plethora of molecular and analytical methods that have only recently become available.

Avian Genomics in Ecology and Evolution

Robert H. S. Kraus
Avian Genomics in Ecology and Evolution Book PDF

Author : Robert H. S. Kraus
Publisher : Springer
Page : 348 pages
File Size : 53,8 Mb
Release : 2019-06-29
Category : Science
ISBN : 9783030164775

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Avian Genomics in Ecology and Evolution by Robert H. S. Kraus Pdf

Birds catch the public imagination like no other group of animals; in addition, birders are perhaps the largest non-professional naturalist community. Genomics and associated bioinformatics have revolutionised daily life in just a few decades. At the same time, this development has facilitated the application of genomics technology to ecological and evolutionary studies, including biodiversity and conservation at all levels. This book reveals how the exciting toolbox of genomics offers new opportunities in all areas of avian biology. It presents contributions from prominent experts at the intersection of avian biology and genomics, and offers an ideal introduction to the world of genomics for students, biologists and bird enthusiasts alike. The book begins with a historical perspective on how genomic technology was adopted by bird ecology and evolution research groups. This led, as the book explains, to a revised understanding of avian evolution, with exciting consequences for biodiversity research as a whole. Lastly, these impacts are illustrated using seminal examples and the latest discoveries from avian biology laboratories around the world.

Human Evolutionary Genetics

Mark Jobling,Edward Hollox,Toomas Kivisild,Chris Tyler-Smith
Human Evolutionary Genetics Book PDF

Author : Mark Jobling,Edward Hollox,Toomas Kivisild,Chris Tyler-Smith
Publisher : Garland Science
Page : 1557 pages
File Size : 52,7 Mb
Release : 2013-06-25
Category : Medical
ISBN : 9781317952251

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Human Evolutionary Genetics by Mark Jobling,Edward Hollox,Toomas Kivisild,Chris Tyler-Smith Pdf

Human Evolutionary Genetics is a groundbreaking text which for the first time brings together molecular genetics and genomics to the study of the origins and movements of human populations. Starting with an overview of molecular genomics for the non-specialist (which can be a useful review for those with a more genetic background), the book shows h

Models and Algorithms for Genome Evolution

Cedric Chauve,Nadia El-Mabrouk,Eric Tannier
Models and Algorithms for Genome Evolution Book PDF

Author : Cedric Chauve,Nadia El-Mabrouk,Eric Tannier
Publisher : Springer Science & Business Media
Page : 328 pages
File Size : 53,9 Mb
Release : 2013-09-17
Category : Computers
ISBN : 9781447152989

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Models and Algorithms for Genome Evolution by Cedric Chauve,Nadia El-Mabrouk,Eric Tannier Pdf

This authoritative text/reference presents a review of the history, current status, and potential future directions of computational biology in molecular evolution. Gathering together the unique insights of an international selection of prestigious researchers, this must-read volume examines the latest developments in the field, the challenges that remain, and the new avenues emerging from the growing influx of sequence data. These viewpoints build upon the pioneering work of David Sankoff, one of the founding fathers of computational biology, and mark the 50th anniversary of his first scientific article. The broad spectrum of rich contributions in this essential collection will appeal to all computer scientists, mathematicians and biologists involved in comparative genomics, phylogenetics and related areas.

Comparative and Evolutionary Genomics of Angiosperm Trees

Andrew Groover,Quentin Cronk
Comparative and Evolutionary Genomics of Angiosperm Trees Book PDF

Author : Andrew Groover,Quentin Cronk
Publisher : Springer
Page : 0 pages
File Size : 54,5 Mb
Release : 2018-09-05
Category : Science
ISBN : 3319841343

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Comparative and Evolutionary Genomics of Angiosperm Trees by Andrew Groover,Quentin Cronk Pdf

Marking the change in focus of tree genomics from single species to comparative approaches, this book covers biological, genomic, and evolutionary aspects of angiosperm trees that provide information and perspectives to support researchers broadening the focus of their research. The diversity of angiosperm trees in morphology, anatomy, physiology and biochemistry has been described and cataloged by various scientific disciplines, but the molecular, genetic, and evolutionary mechanisms underlying this diversity have only recently been explored. Excitingly, advances in genomic and sequencing technologies are ushering a new era of research broadly termed comparative genomics, which simultaneously exploits and describes the evolutionary origins and genetic regulation of traits of interest. Within tree genomics, this research is already underway, as the number of complete genome sequences available for angiosperm trees is increasing at an impressive pace and the number of species for which RNAseq data are available is rapidly expanding. Because they are extensively covered by other literature and are rapidly changing, technical and computational approaches—such as the latest sequencing technologies—are not a main focus of this book. Instead, this comprehensive volume provides a valuable, broader view of tree genomics whose relevance will outlive the particulars of current-day technical approaches. The first section of the book discusses background on the evolution and diversification of angiosperm trees, as well as offers description of the salient features and diversity of the unique physiology and wood anatomy of angiosperm trees. The second section explores the two most advanced model angiosperm tree species (poplars and eucalypts) as well as species that are soon to emerge as new models. The third section describes the structural features and evolutionary histories of angiosperm tree genomes, followed by a fourth section focusing on the genomics of traits of biological, ecological, and economic interest. In summary, this book is a timely and well-referenced foundational resource for the forest tree community looking to embrace comparative approaches for the study of angiosperm trees.

Evolutionary Biology: Genome Evolution, Speciation, Coevolution and Origin of Life

Pierre Pontarotti
Evolutionary Biology Genome Evolution Speciation Coevolution and Origin of Life Book PDF

Author : Pierre Pontarotti
Publisher : Springer
Page : 398 pages
File Size : 43,7 Mb
Release : 2014-07-25
Category : Science
ISBN : 9783319076232

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Evolutionary Biology: Genome Evolution, Speciation, Coevolution and Origin of Life by Pierre Pontarotti Pdf

This book includes the most essential contributions presented at the 17th Evolutionary Biology Meeting in Marseille, which took place in September 2013. It consists of 18 chapters organized according to the following categories: · Molecular and Genome Evolution · Phylogeography of Speciation and Coevolution · Exobiology and Origin of Life The aims of the annual meetings in Marseille, which bring together leading evolutionary biologists and other scientists using evolutionary biology concepts, e.g. for medical research, are to promote the exchange of ideas and to encourage interdisciplinary collaborations. Offering an overview of the latest findings in the field of evolutionary biology, this book represents an invaluable source of information for scientists, teachers and advanced students.

Topological Data Analysis for Genomics and Evolution

Raul Rabadan,Andrew J. Blumberg
Topological Data Analysis for Genomics and Evolution Book PDF

Author : Raul Rabadan,Andrew J. Blumberg
Publisher : Cambridge University Press
Page : 522 pages
File Size : 53,7 Mb
Release : 2019-12-19
Category : Science
ISBN : 9781108757492

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Topological Data Analysis for Genomics and Evolution by Raul Rabadan,Andrew J. Blumberg Pdf

Biology has entered the age of Big Data. A technical revolution has transformed the field, and extracting meaningful information from large biological data sets is now a central methodological challenge. Algebraic topology is a well-established branch of pure mathematics that studies qualitative descriptors of the shape of geometric objects. It aims to reduce comparisons of shape to a comparison of algebraic invariants, such as numbers, which are typically easier to work with. Topological data analysis is a rapidly developing subfield that leverages the tools of algebraic topology to provide robust multiscale analysis of data sets. This book introduces the central ideas and techniques of topological data analysis and its specific applications to biology, including the evolution of viruses, bacteria and humans, genomics of cancer, and single cell characterization of developmental processes. Bridging two disciplines, the book is for researchers and graduate students in genomics and evolutionary biology as well as mathematicians interested in applied topology.

Elements of Evolutionary Genetics

Brian Charlesworth,Deborah Charlesworth
Elements of Evolutionary Genetics Book PDF

Author : Brian Charlesworth,Deborah Charlesworth
Publisher : Roberts
Page : 776 pages
File Size : 51,5 Mb
Release : 2010-02-03
Category : Science
ISBN : STANFORD:36105215340113

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Elements of Evolutionary Genetics by Brian Charlesworth,Deborah Charlesworth Pdf

This textbook shows readers how models of the genetic processes involved in evolution are made (including natural selection, migration, mutation, and genetic drift in finite populations), and how the models are used to interpret classical and molecular genetic data. The material is intended for advanced level undergraduate courses in genetics and evolutionary biology, graduate students in evolutionary biology and human genetics, and researchers in related fields who wish to learn evolutionary genetics. The topics covered include genetic variation, DNA sequence variability and its measurement, the different types of natural selection and their effects (e.g. the maintenance of variation, directional selection, and adaptation), the interactions between selection and mutation or migration, the description and analysis of variation at multiple sites in the genome, genetic drift, and the effects of spatial structure.