Introduction To Smooth Muscle Mechanics

Author : Chun Y. Seow
Publisher : Cambridge Scholars Publishing
Page : 189 pages
File Size : 47,5 Mb
Release : 2020-11-13
Category : Medical
ISBN : 9781527562288

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An Introduction to Smooth Muscle Mechanics (2nd Edition) by Chun Y. Seow Pdf

This second edition is an updated version of an introductory level textbook intended for students who are interested in understanding the mechanical properties of smooth muscle. Compared with skeletal and cardiac muscles, smooth muscle is the least understood in terms of its contraction mechanism and the structure of its contractile apparatus. Nevertheless, it is an important tissue that is vital in many organ functions, such as blood pressure control, intestinal peristalsis, and the emptying of the bladder. Dysfunction of the muscle has been implicated in many diseases such as high blood pressure, asthma, and overactive bladders. This is the only book-length treatment of functional models of a variety of smooth muscle behaviors with their corresponding mathematical descriptions, and offers an easy-to-follow, step-by-step mathematical derivation that will help students to appreciate the muscle cell as a fine-tuned aggregate of mechanisms governed by the fundamental laws of physics. In addition to providing a detailed description of the known subcellular structure and mechanical function of the contractile apparatus of smooth muscle, it also covers experimentation techniques, instrumentation, and data analysis. The book is a must-have information source for anyone interested in smooth muscle cell ultrastructure, physiology, biochemistry, and pharmacology.

Author : Chun y Seow
Publisher : Unknown
Page : 228 pages
File Size : 44,7 Mb
Release : 2016-04-07
Category : Science
ISBN : 1460283333

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Introduction to Smooth Muscle Mechanics by Chun y Seow Pdf

This is an introductory level textbook for students who are interested in understanding mechanical properties of smooth muscle, a vital tissue that is instrumental in many organ functions such as blood pressure control, intestinal peristalsis, and emptying of a bladder. Dysfunction of the muscle has been implicated in many diseases such as high blood pressure, asthma, and overactive bladders. This is the first book-length treatment of functional models of a variety of smooth muscle behaviors with mathematical description. No prior knowledge of muscle physiology is required. An easy-to-follow, step-by-step mathematical derivation helps students to appreciate the muscle cell as a fine-tuned aggregate of mechanisms governed by fundamental laws of physics. This book is useful for students and researchers in life sciences who are interested in the basic mechanism of muscle contraction or who simply use the tissue as a tool in their investigation. Besides a detailed description of the known subcellular structure and mechanical function of the contractile apparatus of smooth muscle, it also covers experimentation techniques, instrumentation, and data analysis, a must-have information source for anyone interested in smooth muscle cell physiology.

Author : Maurice F. Crass,Charles D. Barnes
Publisher : Unknown
Page : 232 pages
File Size : 50,9 Mb
Release : 1982
Category : Medical
ISBN : UOM:39015008070388

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Vascular Smooth Muscle by Maurice F. Crass,Charles D. Barnes Pdf

Vascular Smooth Muscle: Metabolic, Ionic, and Contractile Mechanisms addresses the vascular smooth muscle function by describing plasma lipoprotein structure, synthesis, and transport in relation to the concepts of altered vascular smooth muscle lipid metabolism leading to the genesis of atherosclerotic disease. This book is organized into six chapters and begins with an introduction to the complexities of energy metabolism and how metabolic events can be correlated with a simultaneous quantitative assessment of smooth muscle mechanics and the contractile machinery at the molecular level. The ...

Author : C. Y. Kao,Mary E. Carsten
Publisher : Cambridge University Press
Page : 324 pages
File Size : 41,5 Mb
Release : 1997-08-28
Category : Science
ISBN : 0521482100

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Cellular Aspects of Smooth Muscle Function by C. Y. Kao,Mary E. Carsten Pdf

Smooth muscles line many internal organs and, in general, are involved in moving fluids and slurry around the body. They are controlled by the action of hormones, by nervous stimulation, and can be influenced by drugs. This 1997 book provides a review of our understanding of smooth muscle and integrates molecular, cellular and physiological information with tissue and anatomical studies. Well-known researchers have written chapters giving detailed reviews of our current knowledge of the biochemistry, pharmacology, physiology and anatomy of smooth muscle. In particular, they cover the seven most important areas of smooth muscle function including morphology, electrophysiology, mechanisms of electromechanical and pharmacomechanical coupling, calcium homeostasis, signal transduction, mechanics of contraction, and the contractile proteins. All those interested in muscular contraction will find this book worthwhile, whether they are biochemists, physiologists, or cell biologists.

Author : M.F. III Crass
Publisher : Elsevier
Page : 220 pages
File Size : 47,5 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9780323159876

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Vascular Smooth Muscle: Metabolic, Ionic, and Contractile Mechanisms by M.F. III Crass Pdf

Vascular Smooth Muscle: Metabolic, Ionic, and Contractile Mechanisms addresses the vascular smooth muscle function by describing plasma lipoprotein structure, synthesis, and transport in relation to the concepts of altered vascular smooth muscle lipid metabolism leading to the genesis of atherosclerotic disease. This book is organized into six chapters and begins with an introduction to the complexities of energy metabolism and how metabolic events can be correlated with a simultaneous quantitative assessment of smooth muscle mechanics and the contractile machinery at the molecular level. The next two chapters offer the reader a view of smooth muscle membrane properties in terms of the distribution, transport, and metabolic control of electrolytes and specific aspects of ion conductance and electrical activity. This text also explains how smooth muscle cells regulate their contractile activity through regulation of calcium ion fluxes and the interaction, at the molecular level, of calcium ions with regulatory proteins associated with the contractile apparatus. Reference is made to the relation of possible anomalies in cellular or subcellular smooth muscle metabolic and/or ionic events to the bases of certain types of vascular disease. A chapter that examines the events leading to vascular pathology in the form of atherogenesis concludes the book. This book is intended for researchers and clinicians engaged in the study of smooth muscle and related areas.

Author : David Raeburn,Mark A. Giembycz
Publisher : Birkhäuser
Page : 424 pages
File Size : 49,5 Mb
Release : 2013-03-08
Category : Medical
ISBN : 9783034874083

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Airways Smooth Muscle: Development, and Regulation of Contractility by David Raeburn,Mark A. Giembycz Pdf

Most studies on autonomic innervation of smooth muscle have focused on the short-term mechanisms involved in neurotransmission in physiological and pathophysiological conditions. However recent obser vations of the long-term plasticity of this system, i. e. its capacity for regeneration and for compensatory change in pattern of innervation and expression of cotransmitters and receptors in ageing, following surgery, trauma or in disease, have indicated that an understanding of the mechanisms involved could influence the design of therapeutic regimes. There is increasing evidence for long-term communication between nerves and smooth muscle cells during development and throughout adult life. To date, the trophic interactions between nerves and airway musculature have attracted little interest, consequently, much of the information presented here is drawn from studies using other smooth muscles. However, the questions posed about trophic interactions dur ing development apply as much to airways smooth muscle neuroeffector systems as to other autonomic neuroeffector systems. These are: i) How do developing nerve fibres know where to go and how do they reach their target sites? ii) What determines the density and pattern of inner vation at reaching the effector? iii) How do the nerves survive and maintain their position once established? iv) What factors influence neurochemical differentiation such that genetically multipotential neu rones are triggered to synthesize one or combinations of neurotransmit ters? v) What influence do nerves have on the structure, function and receptor expression of their effector cells? vi) How do diseases interrupt these processes? - see [1].

Author : Kunihiro Sakuma
Publisher : BoD – Books on Demand
Page : 488 pages
File Size : 46,8 Mb
Release : 2015-09-02
Category : Technology & Engineering
ISBN : 9789535121565

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Muscle Cell and Tissue by Kunihiro Sakuma Pdf

In order to complete tissue regeneration, various cells such as neuronal, skeletal, smooth, endothelial, and immune (e.g., macrophage) interact smoothly with each other. This book, Muscle Cells and Tissues, offers a wide range of topics such as stem cells, cell culture, biomaterials, epigenetics, therapeutics, and the creation of tissues and organs. Novel applications for cell and tissue engineering including cell therapy, tissue models, and disease pathology modeling are discussed. The book also deals with the functional role of autophagy in modulating muscle homeostasis and molecular mechanism regulating skeletal muscle mass. The chapters can be interesting for graduate students, postdocs, teachers, physicians, and for executives in biotech and pharmaceutical companies, as well as researchers in the fields of molecular biology and regenerative medicine.

Author : Devendra K. Agrawal,Robert G. Townley
Publisher : CRC Press
Page : 320 pages
File Size : 42,9 Mb
Release : 1990-10-24
Category : Medical
ISBN : 084935904X

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Airway Smooth Muscle by Devendra K. Agrawal,Robert G. Townley Pdf

Airway smooth muscle plays a dominant role in bronchial asthma, as well as a significant role in various pulmonary diseases, such as chronic bronchitis, cystic fibrosis and emphysema. Myogenic, neurogenic, and humoral factors control airway smooth-muscle tone. This text provides a state-of-the-art summary and critical discussion of airway smooth muscle from a multidisciplinary point of view. Topics discussed include morphology, biochemical regulation, mechanical and electrophysiological behavior and reflex control of smooth muscle; the epithelium-derived relaxing factor; and methods to measure smooth muscle function in vivo in humans and experimental animals, as well as in vitro in isolated airway tissues. Also discussed are calcium and potassium channels and receptors for adrenergic, cholinergic and histaminergic systems in modulating receptor-response coupling in airway smooth muscle. Airway Smooth Muscle: Modulation of Receptors and Response provides essential information for researchers, teachers, pulmonary specialists and allergists, and students interested in learning about airway smooth muscle.

Author : J.-F. Ganghoffer,Franco Pastrone
Publisher : Springer Science & Business Media
Page : 133 pages
File Size : 47,7 Mb
Release : 2009-05-14
Category : Science
ISBN : 9783642009112

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Mechanics of Microstructured Solids by J.-F. Ganghoffer,Franco Pastrone Pdf

This is a compendium of reviewed articles presented at the 11th EUROMECH-MECAMAT conference entitled, "Mechancis of microstructured solids: cellular materials, fibre reinforced solids and soft tissues." It provides all the latest information in the field.

Author : Newman L. Stephens
Publisher : New York : M. Dekker
Page : 600 pages
File Size : 45,8 Mb
Release : 1984
Category : Science
ISBN : UOM:39015006031556

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Smooth Muscle Contraction by Newman L. Stephens Pdf

Author : R.D. Bauer,R. Busse
Publisher : Springer Science & Business Media
Page : 315 pages
File Size : 46,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642670206

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The Arterial System by R.D. Bauer,R. Busse Pdf

This book summarizes the papers presented at the symposium "Dynamics and Regulation of the Arterial System" held at Erlangen on 28-30 October 1977 in honor of Professor Erik Wetterer. The aim of the symposium was an inten sive exchange of ideas within a mUltidisciplinary group of scientists who are specialists in their fields of research. It is obvious that a two-day symposium covering such a wide range of topics could only highlight certain aspects of the latest research on the cardiovascular system. The book is divided into three sections. The first part deals with arterial hemo dynamics. Emphasized are the mechanical properties of the arterial wall, in particular the smooth muscle, fundamental parameters for the description of pulse wave propagation, such as attenuation, phase velocity, and reflection of pulse waves. Furthermore, new methods for recording arterial diameters and the latest results in determining pulsatile pressure and pulsatile diameter of arteries in vivo as well as from calculations based on models of the arterial system are presented. The second part deals with applications of the control theory and the principles of optimality of the cardiovascular system in toto and of single regions of this system. Contributions to research in the field of regulation of blood volume and of regional hemodynamics are also presented. The third part covers problems of interaction of the heart and the arterial system, including fluid mechanics of the aortic valves and the coronary blood flow under normal and pathologic conditions.

Author : Andrea Aliverti,Antonio Pedotti
Publisher : Springer
Page : 411 pages
File Size : 48,7 Mb
Release : 2014-06-19
Category : Medical
ISBN : 9788847056473

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Mechanics of Breathing by Andrea Aliverti,Antonio Pedotti Pdf

This book offers a state-of-the-art description of the complexity of the healthy and pathological respiratory system, with particular reference to the mechanics of the airways, lung and chest wall. Detailed information is provided on new insights into the mechanics of breathing that have been obtained through technological innovations in measurement systems, cutting-edge modeling techniques and novel approaches to functional imaging of the respiratory system. It is explained how these advances permit the assessment of emerging treatment approaches, including new drugs, innovative surgical techniques and modes of mechanical ventilation and new forms of rehabilitation. In order to ensure comprehensive coverage of the subject, the editor has assembled a multidisciplinary team of authors comprising basic scientists in respiratory medicine, chest and intensive care physicians and bioengineers involved in both modeling and instrumentation. The book is intended for intensive care physicians, respirologists, physiologists, rehabilitation specialists, basic scientists in respiration, research and clinical fellows, biomedical engineers involved with respiratory mechanics and respiratory therapists. They will update their knowledge and improve their clinical expertise.

Author : W. Herzog
Publisher : John Wiley & Sons
Page : 586 pages
File Size : 44,9 Mb
Release : 2000-10-03
Category : Science
ISBN : 0471492388

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Skeletal Muscle Mechanics by W. Herzog Pdf

Dieses Teilgebiet der Biomechanik ist für Sportwissenschaftler und Physiologen von großer Bedeutung! Die umfassende, aktuelle Abhandlung der Skelettmuskelmechanik beschäftigt sich mit drei Themenkreisen: den Mechanismen der Skelettmuskelkontraktion, der Muskelfunktion in vivo und theoretischen Modellen der Muskelfunktion. Auch ein knapper historischer Abriß und ein Ausblick auf noch offene Fragen fehlen nicht. (08/00)

Author : Edwin E. Daniel,Tadao Tomita,Seigi Tsuchida,Minoru Watanabe
Publisher : CRC Press
Page : 470 pages
File Size : 47,7 Mb
Release : 1992-04-01
Category : Medical
ISBN : 0849367484

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Sphincters by Edwin E. Daniel,Tadao Tomita,Seigi Tsuchida,Minoru Watanabe Pdf

Sphincters: Normal Function-Changes in Diseases is the first book devoted to sphincter function in health and disease. It provides basic information about the function of sphincters and their physiological controls, as well as a comprehensive examination of the various sphincters in the body. The book also presents the current understanding of disordered control of sphincter function in disease. Sphincters: Normal Function-Changes in Diseases is an important acquisition for scientists, physicians, and medical students interested in sphincter function and how to treat their disorders.

Author : L. Barr,G. Christ
Publisher : Elsevier Science
Page : 0 pages
File Size : 48,6 Mb
Release : 2000-10-05
Category : Science
ISBN : 0762306130

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A Functional View of Smooth Muscle by L. Barr,G. Christ Pdf

The idea of this volume was to provide for advanced graduate students, medical students, and postdoctoral who are beginning to do research related to smooth muscle a sampling of the orienting ideas of the researchers working on problems in smooth muscle physiology and pathophysiology. Therefore, an essential goal of the volume is to identify the lines of investigation that are currently being pursued by investigators whose concerns are with smooth muscle or with organs with parenchumal tissues consisting of smooth muscle. Various types of smooth muscle constitute the parenchuma or characteristic tissues of a large number of organs or regions of organs. In each case, the phenotype is distinctly different and, while smooth muscles do not exhibit the diversity of epithelia, they nevertheless span a great range of physiological responsiveness. Undoubtedly, the variations in the characteristic responses of different smooth muscles result from the expression of sets of transduction subserving proteins. However, it is what the sets are and how they work and are regulated that fascinated the physiologist. In this book, the contrast between sameness and diversity recurs as a theme.