An Introduction To Smooth Muscle Mechanics 2nd Edition

Author : Chun Y. Seow
Publisher : Cambridge Scholars Publishing
Page : 189 pages
File Size : 47,7 Mb
Release : 2020-11-13
Category : Medical
ISBN : 9781527562288

Get Book

An Introduction to Smooth Muscle Mechanics (2nd Edition) by Chun Y. Seow Pdf

This second edition is an updated version of an introductory level textbook intended for students who are interested in understanding the mechanical properties of smooth muscle. Compared with skeletal and cardiac muscles, smooth muscle is the least understood in terms of its contraction mechanism and the structure of its contractile apparatus. Nevertheless, it is an important tissue that is vital in many organ functions, such as blood pressure control, intestinal peristalsis, and the emptying of the bladder. Dysfunction of the muscle has been implicated in many diseases such as high blood pressure, asthma, and overactive bladders. This is the only book-length treatment of functional models of a variety of smooth muscle behaviors with their corresponding mathematical descriptions, and offers an easy-to-follow, step-by-step mathematical derivation that will help students to appreciate the muscle cell as a fine-tuned aggregate of mechanisms governed by the fundamental laws of physics. In addition to providing a detailed description of the known subcellular structure and mechanical function of the contractile apparatus of smooth muscle, it also covers experimentation techniques, instrumentation, and data analysis. The book is a must-have information source for anyone interested in smooth muscle cell ultrastructure, physiology, biochemistry, and pharmacology.

Author : Chun y Seow
Publisher : Unknown
Page : 228 pages
File Size : 52,5 Mb
Release : 2016-04-07
Category : Science
ISBN : 1460283333

Get Book

Introduction to Smooth Muscle Mechanics by Chun y Seow Pdf

This is an introductory level textbook for students who are interested in understanding mechanical properties of smooth muscle, a vital tissue that is instrumental in many organ functions such as blood pressure control, intestinal peristalsis, and emptying of a bladder. Dysfunction of the muscle has been implicated in many diseases such as high blood pressure, asthma, and overactive bladders. This is the first book-length treatment of functional models of a variety of smooth muscle behaviors with mathematical description. No prior knowledge of muscle physiology is required. An easy-to-follow, step-by-step mathematical derivation helps students to appreciate the muscle cell as a fine-tuned aggregate of mechanisms governed by fundamental laws of physics. This book is useful for students and researchers in life sciences who are interested in the basic mechanism of muscle contraction or who simply use the tissue as a tool in their investigation. Besides a detailed description of the known subcellular structure and mechanical function of the contractile apparatus of smooth muscle, it also covers experimentation techniques, instrumentation, and data analysis, a must-have information source for anyone interested in smooth muscle cell physiology.

Author : C. Y. Kao,Mary E. Carsten
Publisher : Cambridge University Press
Page : 324 pages
File Size : 45,9 Mb
Release : 1997-08-28
Category : Science
ISBN : 0521482100

Get Book

Cellular Aspects of Smooth Muscle Function by C. Y. Kao,Mary E. Carsten Pdf

Smooth muscles line many internal organs and, in general, are involved in moving fluids and slurry around the body. They are controlled by the action of hormones, by nervous stimulation, and can be influenced by drugs. This 1997 book provides a review of our understanding of smooth muscle and integrates molecular, cellular and physiological information with tissue and anatomical studies. Well-known researchers have written chapters giving detailed reviews of our current knowledge of the biochemistry, pharmacology, physiology and anatomy of smooth muscle. In particular, they cover the seven most important areas of smooth muscle function including morphology, electrophysiology, mechanisms of electromechanical and pharmacomechanical coupling, calcium homeostasis, signal transduction, mechanics of contraction, and the contractile proteins. All those interested in muscular contraction will find this book worthwhile, whether they are biochemists, physiologists, or cell biologists.

Author : Edith Bülbring
Publisher : Hodder Education
Page : 714 pages
File Size : 51,9 Mb
Release : 1970
Category : Science
ISBN : UOM:39015000826563

Get Book

Smooth Muscle by Edith Bülbring Pdf

Author : International Union of Physiological Sciences. Satellite Conference on Smooth Muscle Contraction,Marion J. Siegman,Andrew Paul Somlyo,Newman L. Stephens,International Union of Physiological Sciences. Congress
Publisher : New York : Liss
Page : 544 pages
File Size : 46,7 Mb
Release : 1987
Category : Nature
ISBN : UOM:39015012539279

Get Book

Regulation and Contraction of Smooth Muscle by International Union of Physiological Sciences. Satellite Conference on Smooth Muscle Contraction,Marion J. Siegman,Andrew Paul Somlyo,Newman L. Stephens,International Union of Physiological Sciences. Congress Pdf

Author : Edwin Daniel
Publisher : Unknown
Page : 748 pages
File Size : 55,7 Mb
Release : 2014-01-15
Category : Electronic
ISBN : 1468427520

Get Book

Smooth Muscle by Edwin Daniel Pdf

Author : David Rubenstein,Wei Yin,Mary D. Frame
Publisher : Academic Press
Page : 633 pages
File Size : 44,5 Mb
Release : 2021-03-13
Category : Science
ISBN : 9780128180358

Get Book

Biofluid Mechanics by David Rubenstein,Wei Yin,Mary D. Frame Pdf

Biofluid Mechanics: An Introduction to Fluid Mechanics, Macrocirculation, and Microcirculation, Third Edition shows how fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement, renal transport, and other specialty circulations. This new edition contains new homework problems and worked examples, including MATLAB-based examples. In addition, new content has been added on such relevant topics as Womersley and Oscillatory Flows. With advanced topics in the text now denoted for instructor convenience, this book is particularly suitable for both senior and graduate-level courses in biofluids. Uses language and math that is appropriate and conducive for undergraduate and first-year graduate learning Contains new worked examples and end-of-chapter problems Covers topics in the traditional biofluids curriculum, also addressing other systems in the body Discusses clinical applications throughout the book, providing practical applications for the concepts discussed Includes more advanced topics to help instructors teach an undergraduate course without a loss of continuity in the class

Author : Y. C. Fung
Publisher : Springer Science & Business Media
Page : 443 pages
File Size : 48,8 Mb
Release : 2013-06-29
Category : Medical
ISBN : 9781475717525

Get Book

Biomechanics by Y. C. Fung Pdf

The motivation for writing aseries ofbooks on biomechanics is to bring this rapidly developing subject to students of bioengineering, physiology, and mechanics. In the last decade biomechanics has become a recognized disci pline offered in virtually all universities. Yet there is no adequate textbook for instruction; neither is there a treatise with sufficiently broad coverage. A few books bearing the title of biomechanics are too elementary, others are too specialized. I have long feIt a need for a set of books that will inform students of the physiological and medical applications of biomechanics, and at the same time develop their training in mechanics. We cannot assume that all students come to biomechanics already fully trained in fluid and solid mechanics; their knowledge in these subjects has to be developed as the course proceeds. The scheme adopted in the present series is as follows. First, some basic training in mechanics, to a level about equivalent to the first seven chapters of the author's A First Course in Continuum Mechanics (Prentice-Hall,lnc. 1977), is assumed. We then present some essential parts of biomechanics from the point of view of bioengineering, physiology, and medical applications. In the meantime, mechanics is developed through a sequence of problems and examples. The main text reads like physiology, while the exercises are planned like a mechanics textbook. The instructor may fil1 a dual role: teaching an essential branch of life science, and gradually developing the student's knowledge in mechanics.

Author : Alison McConnell
Publisher : Elsevier Health Sciences
Page : 403 pages
File Size : 42,8 Mb
Release : 2013-04-18
Category : Medical
ISBN : 9780702054556

Get Book

Respiratory Muscle Training by Alison McConnell Pdf

Respiratory Muscle Training: theory and practice is the world’s first book to provide an "everything-you-need-to-know" guide to respiratory muscle training (RMT). Authored by an internationally-acclaimed expert, it is an evidence-based resource, built upon current scientific knowledge, as well as experience at the cutting-edge of respiratory training in a wide range of settings. The aim of the book is to give readers: 1) an introduction to respiratory physiology and exercise physiology, as well as training theory; 2) an understanding of how disease affects the respiratory muscles and the mechanics of breathing; 3) an insight into the disease-specific, evidence-based benefits of RMT; 4) advice on the application of RMT as a standalone treatment, and as part of a rehabilitation programme; and finally, 5) guidance on the application of functional training techniques to RMT. The book is divided into two parts – theory and practice. Part I provides readers with access to the theoretical building blocks that support practice. It explores the evidence base for RMT as well as the different methods of training respiratory muscles and their respective efficacy. Part II guides the reader through the practical implementation of the most widely validated form of RMT, namely inspiratory muscle resistance training. Finally, over 150 "Functional" RMT exercises are described, which incorporate a stability and/or postural challenge – and address specific movements that provoke dyspnoea. Respiratory Muscle Training: theory and practice is supported by a dedicated website (www.physiobreathe.com), which provides access to the latest information on RMT, as well as video clips of all exercises described in the book. Purchasers will also receive a three-month free trial of the Physiotec software platform (via www.physiotec.ca), which allows clinicians to create bespoke training programmes (including video clips) that can be printed or emailed to patients. Introductory overviews of respiratory and exercise physiology, as well as training theory Comprehensive, up-to-date review of respiratory muscle function, breathing mechanics and RMT Analysis of the interaction between disease and respiratory mechanics, as well as their independent and combined influence upon exercise tolerance Analysis of the rationale and application of RMT to over 20 clinical conditions, e.g., COPD, heart failure, obesity, mechanical ventilation Evidence-based guidance on the implementation of inspiratory muscle resistance training Over 150 functional exercises that incorporate a breathing challenge www.physiobreathe.com - access up-to-date information, video clips of exercises and a three-month free trial of Physiotec’s RMT exercise module (via www.physiotec.ca)

Author : Arthur B. Ritter,Vikki Hazelwood,Antonio Valdevit,Alfred N. Ascione
Publisher : CRC Press
Page : 542 pages
File Size : 52,5 Mb
Release : 2011-05-24
Category : Medical
ISBN : 9781439812327

Get Book

Biomedical Engineering Principles, Second Edition by Arthur B. Ritter,Vikki Hazelwood,Antonio Valdevit,Alfred N. Ascione Pdf

Current demand in biomedical sciences emphasizes the understanding of basic mechanisms and problem solving rather than rigid empiricism and factual recall. Knowledge of the basic laws of mass and momentum transport as well as model development and validation, biomedical signal processing, biomechanics, and capstone design have indispensable roles in the engineering analysis of physiological processes. To this end, an introductory, multidisciplinary text is a must to provide the necessary foundation for beginning biomedical students. Assuming no more than a passing acquaintance with molecular biology, physiology, biochemistry, and signal processing, Biomedical Engineering Principles, Second Edition provides just such a solid, accessible grounding to this rapidly advancing field. Acknowledging the vast range of backgrounds and prior education from which the biomedical field draws, the organization of this book lends itself to a tailored course specific to the experience and interests of the student. Divided into four sections, the book begins with systems physiology, transport processes, cell physiology, and the cardiovascular system. Part I covers systems analysis, biological data, and modeling and simulation in experimental design, applying concepts of diffusion, and facilitated and active transport. Part II presents biomedical signal processing, reviewing frequency, periodic functions, and Fourier series as well as signal acquisition and processing techniques. Part III presents the practical applications of biomechanics, focusing on the mechanical and structural properties of bone, musculoskeletal, and connective tissue with respect to joint range, load bearing capacity, and electrical stimulation. The final part highlights capstone design, discussing design perspectives for living and nonliving systems, the role of the FDA, and the project timeline from inception to proof of concept. Cutting across many disciplines, Biomedical Engineering Principles, Second Edition offers illustrative examples as well as problems and discussion questions designed specifically for this book to provide a readily accessible, widely applicable introductory text.

Author : John Squire
Publisher : Springer Science & Business Media
Page : 704 pages
File Size : 42,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461331834

Get Book

The Structural Basis of Muscular Contraction by John Squire Pdf

Muscular contraction provides one of the most fascinating topics for a biophysicist to study. Although muscle comprises a molecular machine whereby chemical energy is converted to mechanical work, its action in producing force is something that is readily observable in everyday life, a feature that does not apply to most other structures of biophysical inter est. In addition, muscle is so beautifully organized at the microscopic level that those important structural probes, electron microscopy (with the associated image analysis methods) and X-ray diffraction, have pro vided a wealth of information about the arrangements of the constituent proteins in a variety of muscle types. But, despite all this, the answer to the question "How does muscle work?" is still uncertain, especially with regard to the molecular events by which force is actually generated, and the question remains one of the major unsolved problems in biology. With this problem in mind, this book has been written to collect together the available evidence on the structures of the muscle fila ments and on their arrangements in different muscle cells, to extract the common structural features of these cells, and thus to attempt to define a possible series of mechanical steps that will describe at molecular resolu tion the process by which force is generated. The book cannot be considered to be an introductory text; in fact, it presents a very detailed account of muscle structure as gleaned mainly from electron microscopy and X-ray diffraction.

Author : Kunihiro Sakuma
Publisher : BoD – Books on Demand
Page : 488 pages
File Size : 43,6 Mb
Release : 2015-09-02
Category : Technology & Engineering
ISBN : 9789535121565

Get Book

Muscle Cell and Tissue by Kunihiro Sakuma Pdf

In order to complete tissue regeneration, various cells such as neuronal, skeletal, smooth, endothelial, and immune (e.g., macrophage) interact smoothly with each other. This book, Muscle Cells and Tissues, offers a wide range of topics such as stem cells, cell culture, biomaterials, epigenetics, therapeutics, and the creation of tissues and organs. Novel applications for cell and tissue engineering including cell therapy, tissue models, and disease pathology modeling are discussed. The book also deals with the functional role of autophagy in modulating muscle homeostasis and molecular mechanism regulating skeletal muscle mass. The chapters can be interesting for graduate students, postdocs, teachers, physicians, and for executives in biotech and pharmaceutical companies, as well as researchers in the fields of molecular biology and regenerative medicine.

Author : David Rubenstein,Wei Yin,Mary D. Frame
Publisher : Academic Press
Page : 410 pages
File Size : 54,5 Mb
Release : 2011-11-02
Category : Science
ISBN : 9780123813848

Get Book

Biofluid Mechanics by David Rubenstein,Wei Yin,Mary D. Frame Pdf

Both broad and deep in coverage, Rubenstein shows that fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement and renal transport. Each section initiates discussion with governing equations, derives the state equations and then shows examples of their usage. Clinical applications, extensive worked examples, and numerous end of chapter problems clearly show the applications of fluid mechanics to biomedical engineering situations. A section on experimental techniques provides a springboard for future research efforts in the subject area. Uses language and math that is appropriate and conducive for undergraduate learning, containing many worked examples and end of chapter problems All engineering concepts and equations are developed within a biological context Covers topics in the traditional biofluids curriculum, as well as addressing other systems in the body that can be described by biofluid mechanics principles, such as air flow through the lungs, joint lubrication, intraocular fluid movement, and renal transport Clinical applications are discussed throughout the book, providing practical applications for the concepts discussed.

Author : Jeffrey O. Hollinger
Publisher : CRC Press
Page : 646 pages
File Size : 40,8 Mb
Release : 2011-11-28
Category : Medical
ISBN : 9781439812563

Get Book

An Introduction to Biomaterials, Second Edition by Jeffrey O. Hollinger Pdf

A practical road map to the key families of biomaterials and their potential applications in clinical therapeutics, Introduction to Biomaterials, Second Edition follows the entire path of development from theory to lab to practical application. It highlights new biocompatibility issues, metrics, and statistics as well as new legislation for intellectual property. Divided into four sections (Biology, Biomechanics, Biomaterials Interactions; Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property; Biomaterials Compositions; and Biomaterials Applications), this dramatically revised edition includes both new and revised chapters on cells, tissues, and signaling molecules in wound healing cascades, as well as two revised chapters on standardized materials testing with in vitro and in vivo paradigms consistent with regulatory guidelines. Emphasizing biocompatibility at the biomaterial-host interface, it investigates cell-cell interactions, cell-signaling and the inflammatory and complement cascades, specific interactions of protein-adsorbed materials, and other inherent biological constraints including solid-liquid interfaces, diffusion, and protein types. Unique in its inclusion of the practicalities of biomaterials as an industry, the book also covers the basic principles of statistics, new U.S. FDA information on the biomaterials-biology issues relevant to patent applications, and considerations of intellectual property and patent disclosure. With nine completely new chapters and 24 chapters extensively updated and revised with new accomplishments and contemporary data, this comprehensive introduction discusses 13 important classes of biomaterials, their fundamental and applied research, practical applications, performance properties, synthesis and testing, potential future applications, and commonly matched clinical applications. The authors include extensive references, to create a comprehensive, yet manageable didactic work that is an invaluable desk references and instructional text for undergraduates and working professionals alike.

Author : T. B. Bolton,T. Tomita
Publisher : Unknown
Page : 568 pages
File Size : 48,9 Mb
Release : 1996
Category : Medical
ISBN : UOM:39015038154343

Get Book

Smooth Muscle Excitation by T. B. Bolton,T. Tomita Pdf

This book is a compendium of the latest electrophysiological research on smooth muscles from an international collection of authors. It includes recent discoveries in calcium stores and their relationship to contraction and to electrical changes in the membrane. A major section of the book concentrates on calcium release mechanisms in the cell, their control, and the consequences of calcium release in the cell for membrane events. Smooth Muscle Excitation also covers the effects of chemicals released from adjacent cells. Key Features * State-of-the-art volume that represents a synopsis of all work currently being undertaken in this area throughout the world * Content covers both basic and clinical research * Provides a range of drug development studies * Presents contributions from many internationally recognized smooth muscle physiologists