Ipsc 2023

Author : Agus Wahyudi Salasa Gama,I Made Surya Prayoga,I Kadek Bagiana
Publisher : European Alliance for Innovation
Page : 503 pages
File Size : 48,7 Mb
Release : 2023-12-19
Category : Business & Economics
ISBN : 9781631904363

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IPSC 2023 by Agus Wahyudi Salasa Gama,I Made Surya Prayoga,I Kadek Bagiana Pdf

IPSC organized by Faculty of Economic and Business Universitas Mahasaraswati Denpasar, Universiti Teknologi Mara-Malaysia and Universitas Terbuka-Indonesia. IPSC aims to address the challenges associated with the modern research produced in the public sector. As new advancements are constantly emerging, early-career academics, scholars, and researchers are finding it harder to stay abreast of these developments. The conference seeks to provide support to these individuals by helping them stay up-to-date with the latest advancements. The 5th International Public Sector Conference (IPSC) 2023 with the theme "Strategic Alliance and Sustainabillity of Public Sector Organization in Digital Era" with focus and scopes encourages researchers of all levels to showcase their investigative research findings by presenting appropriate papers or presentations at the event, regardless of their particular educational research field. Those who submit the best research articles will be duly rewarded with an incredible opportunity to have their research outcomes published in top-tier publications and magazines that are globally renowned. This not only helps them gain the necessary exposure to spread the word about their research work among international research communities but also opens up numerous opportunities for funding and conducting advanced research projects.

Author : Koh-ichi Nagata
Publisher : Springer Nature
Page : 355 pages
File Size : 41,7 Mb
Release : 2024-05-22
Category : Electronic
ISBN : 9781071638101

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Cerebral Cortex Development by Koh-ichi Nagata Pdf

Author : Anonim
Publisher : Elsevier
Page : 448 pages
File Size : 55,5 Mb
Release : 2024-01-11
Category : Science
ISBN : 9780443193439

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Advances in Protein Chemistry and Structural Biology by Anonim Pdf

Advances in Protein Chemistry and Structural Biology, Volume 138 covers reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design. Chapters in this release include Proteomic Applications in Identifying Protein-Protein Interactions, Understanding functions of eEF1 translation elongation factors beyond translation. A proteomic approach, Proteomics provides insights into theranostic potential of extracellular vesicles, Towards a shareable functional analysis of the structural proteome, Functional unfoldomics, In-silico Network Pharmacology Study on Glycyrrhiza glabra: Analyzing the Immune-Boosting phytochemical properties of Siddha Medicinal Plant against COVID-19, and more. Other chapters cover In silico Network Pharmacology Analysis and Molecular Docking Validation of Swasa Kudori for Screening Druggable Phytoconstituents of Asthma, Proteomics and Genomics Insights on Malignant Osteosarcoma, Application of functional proteomics in understanding RNA Virus-Mediated Infection, Biofilm proteome of Staphylococcus aureus: implications for therapeutic interventions to biofilm-associated infections, A computational pipeline elucidating functions of conserved hypothetical Trypanosoma cruzi proteins based on public proteomic data, Functional Proteomics based on Protein Microarray Technology for Biomedical Research, and an Analysis of endoglucanases production using proteomics and metatranscriptomics. Includes new information about Protein Aggregation Presents chapters by a wide range of leading experts Cover new, cutting-edge information that will serve as an essential addition to any bookshelf or laboratory

Author : Markus H. Kuehn,Wei Zhu
Publisher : Springer Nature
Page : 331 pages
File Size : 44,8 Mb
Release : 2023-11-23
Category : Medical
ISBN : 9783031423499

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Human iPSC-derived Disease Models for Drug Discovery by Markus H. Kuehn,Wei Zhu Pdf

Since their development a decade ago, human induced pluripotent stem cells (iPSC) have revolutionized the study of human disease, given rise to regenerative medicine technologies, and provided exceptional opportunities for pharmacologic research. These cells provide an essentially unlimited supply of cell types that are difficult to obtain from patients, such as neurons or cardiomyocytes, or are difficult to maintain in primary cell culture. iPSC can be obtained from patients afflicted with a particular disease but, in combination with recently developed gene editing techniques, can also be modified to generate disease models. Moreover, the new techniques of 3 Dimensional printing and materials science facilitate the generation of organoids that can mirror organs under disease conditions. These properties make iPSC powerful tools to study how diseases develop and how they may be treated. In addition, iPSC can also be used to treat conditions in which the target cell population has been lost and such regenerative approaches hold great promise for currently untreatable diseases, including cardiac failure or photoreceptor degenerations.

Author : Anonim
Publisher : BoD – Books on Demand
Page : 182 pages
File Size : 53,6 Mb
Release : 2024-01-31
Category : Science
ISBN : 9781837692613

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Advances in Pluripotent Stem Cells by Anonim Pdf

Human pluripotent stem cells (hPSCs) are advantageous cell sources for disease remodeling and drug screening, particularly for regenerative medicine. State-of-the-art updates have highlighted the feasibility of hPSCs for the large-scale preparation of diverse kinds of stem cells and functional cells, such as mesenchymal stem/stromal cells (MSCs), hematopoietic stem cells (HSCs), neural stem cells (NSCs), natural killer (NK) cells, and chimeric antigen receptor-transduced T cells (CAR-Ts). With the aid of preclinical investigations and clinical practice, hPSCs have been recognized as promising therapeutic cell sources with excellent properties for treating a variety of refractory and recurrent diseases. This book provides a comprehensive overview of advances in pluripotent stem cells.

Author : Khang, Alex
Publisher : IGI Global
Page : 393 pages
File Size : 43,5 Mb
Release : 2024-02-09
Category : Medical
ISBN : 9798369332191

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AI-Driven Innovations in Digital Healthcare: Emerging Trends, Challenges, and Applications by Khang, Alex Pdf

Within the healthcare sector, a pressing need for transformative changes is growing. From chronic diseases to complex diagnostic procedures, the industry stands at the crossroads of technological innovation and a burgeoning demand for more efficient, precise interventions. Patient expectations are soaring, and the deluge of medical data is overwhelming traditional healthcare systems. It is within this challenging environment that AI-Driven Innovations in Digital Healthcare: Emerging Trends, Challenges, and Applications emerges as a beacon of insight and practical solutions. The traditional healthcare framework is struggling to keep pace with the diverse demands of patients and the ever-expanding volume of medical data. As diseases become more intricate, attempts to provide timely identification and precise treatment of ailments become increasingly elusive. The urgency for a paradigm shift in healthcare delivery is emphasized by the critical need for early interventions, particularly in disease prediction. This challenge necessitates a holistic approach that harnesses the power of artificial intelligence (AI) and innovative technologies to steer healthcare toward a more responsive and patient-centric future.

Author : YCT Expert Team
Publisher : YOUTH COMPETITION TIMES
Page : 450 pages
File Size : 44,5 Mb
Release : 2024-05-22
Category : Antiques & Collectibles
ISBN : 8210379456XXX

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2024-25 RRB Technician Grade-I Signal Basic Science & Engineering Study Material Question Bank by YCT Expert Team Pdf

2024-25 RRB Technician Grade-I Signal Basic Science & Engineering Study Material Question Bank 448 895 E. This book contains 2500 questions and also covers Physics Fundamentals, Electricity and Magnetism and Electronics and Measurements.

Author : Elizabeth D. Buttermore
Publisher : Academic Press
Page : 374 pages
File Size : 40,6 Mb
Release : 2022-09-09
Category : Medical
ISBN : 9780128222782

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Phenotyping of Human iPSC-derived Neurons by Elizabeth D. Buttermore Pdf

Phenotyping of Human iPSC-derived Neurons: Patient-Driven Research examines the steps in a preclinical pipeline that utilizes iPSC-derived neuronal technology to better understand neurological disorders and identify novel therapeutics, also providing considerations and best practices. By presenting example projects that identify phenotypes and mechanisms relevant to autism spectrum disorder and epilepsy, this book allows readers to understand what considerations are important to assess at the start of project design. Sections address reproducibility issues and advances in technology at each stage of the pipeline and provide suggestions for improvement. From patient sample collection and proper controls to neuronal differentiation, phenotyping, screening, and considerations for moving to the clinic, these detailed descriptions of each stage of the pipeline will help everyone, regardless of stage in the pipeline. In recent years, drug discovery in the neurosciences has struggled to identify novel therapeutics for patients with varying indications, including epilepsy, chronic pain, and psychosis. Current treatment options for such patients are decades old and offer little relief with many side effects. One explanation for this lull in novel therapeutics is a lack of novel target identification for neurological disorders (and target identification requires exemplar preclinical data). To improve on the preclinical work that often relies on rodent modeling, the field has begun utilizing patient-derived induced pluripotent stem cells (iPSCs) to differentiate neurons in vitro for preclinical characterization of neurological disease and target identification. Discusses techniques and new technology for iPSC culturing and neuronal differentiation to establish best practices in the lab Outlines considerations for phenotypic assay development Provides information about the successes, failures, and implications of phenotyping and screening with iPSC-derived neurons Describes how human iPSC-derived neurons are being used for preclinical discovery research as well as the development of therapeutics utilizing hiPSC-derived neurons

Author : Kursad Turksen
Publisher : Springer Nature
Page : 228 pages
File Size : 43,6 Mb
Release : 2023-12-09
Category : Science
ISBN : 9781071635377

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Stem Cells and Lineage Commitment by Kursad Turksen Pdf

This detailed volume explores a variety of techniques used to study lineage commitment in stem cells. Further elucidation of the process that stem cells undergo on their way to becoming more specified cell types is vital for a more complete understanding of cell biology and overall physiology. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Stem Cells and Lineage Commitment: Methods and Protocols serves as an ideal guide for experts and novices in the field of stem cell biology.

Author : Jianyi Zhang,Zhen Ma,Vahid Serpooshan,Yuji Nakada,Keiichi Fukuda
Publisher : Frontiers Media SA
Page : 234 pages
File Size : 55,7 Mb
Release : 2024-02-26
Category : Technology & Engineering
ISBN : 9782832545263

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Bioengineering and Biotechnology Approaches in Cardiovascular Regenerative Medicine, Volume II by Jianyi Zhang,Zhen Ma,Vahid Serpooshan,Yuji Nakada,Keiichi Fukuda Pdf

This Research Topic is Volume II of a series. The previous volume, which has attracted over 40,000 views can be found here: Bioengineering and Biotechnology Approaches in Cardiovascular Regenerative MedicineCardiovascular diseases continue to be the leading cause of death while available clinical interventions have limited contributions to heart repair and regeneration. Cardiovascular regenerative medicine, characterized by a unique integration of biology, physical sciences, and bioengineering principles, has emerged as one of the most promising fields of translational research to regenerate the adult human heart.

Author : Ralf Pörtner
Publisher : Springer Nature
Page : 497 pages
File Size : 53,7 Mb
Release : 2024-02-11
Category : Science
ISBN : 9783031456695

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Biopharmaceutical Manufacturing by Ralf Pörtner Pdf

This volume “Cell Engineerring 11 - Biopharmaceutical Manufacturing: Progress, Trends and Challenges” is a source of the latest innovative research and technical development in biomanufacturing systems. It is organised into 2 parts: 1) Manufacturing of recombinant therapeutic proteins (e.g. therapeutic antibodies, biosimilars/biogenerics) and 2) Manufacturing aspects of cell and gene therapy. Each with selected chapters on the following topics for both up- and downstream, such as: Advanced process strategies, especially continuous manufacturing, Advanced culture techniques, especially single-use systems, Process transfer, scale-up/scale-down models, Processing advances/Manufacturing productivity/efficiency, Model-assisted process understanding and development/Digital Twins, Process controls and analytics, Quality control, Quality by design, Facility design and full-scale commercial systems, manufacturing technology innovation. The book comprises contributions of experts from academia and industry active in the field of cell culture development for the production of recombinant proteins, cell therapy and gene therapy, with consideration of Digital Twin ́s and facility design. The knowledge and expertise of the authors cover disciplines like cell biology, engineering, biotechnology and biomedical sciences. Inevitably, some omissions will occur in the test, but the authors have sought to avoid duplications by extensive cross-referencing to chapters in other volumes of this series and elsewhere. We hope the volume provides a useful compendium of techniques for scientists in industrial and research laboratories active in this field.

Author : David Padua
Publisher : Springer Science & Business Media
Page : 2211 pages
File Size : 50,8 Mb
Release : 2014-07-08
Category : Computers
ISBN : 9780387097664

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Encyclopedia of Parallel Computing by David Padua Pdf

Containing over 300 entries in an A-Z format, the Encyclopedia of Parallel Computing provides easy, intuitive access to relevant information for professionals and researchers seeking access to any aspect within the broad field of parallel computing. Topics for this comprehensive reference were selected, written, and peer-reviewed by an international pool of distinguished researchers in the field. The Encyclopedia is broad in scope, covering machine organization, programming languages, algorithms, and applications. Within each area, concepts, designs, and specific implementations are presented. The highly-structured essays in this work comprise synonyms, a definition and discussion of the topic, bibliographies, and links to related literature. Extensive cross-references to other entries within the Encyclopedia support efficient, user-friendly searchers for immediate access to useful information. Key concepts presented in the Encyclopedia of Parallel Computing include; laws and metrics; specific numerical and non-numerical algorithms; asynchronous algorithms; libraries of subroutines; benchmark suites; applications; sequential consistency and cache coherency; machine classes such as clusters, shared-memory multiprocessors, special-purpose machines and dataflow machines; specific machines such as Cray supercomputers, IBM’s cell processor and Intel’s multicore machines; race detection and auto parallelization; parallel programming languages, synchronization primitives, collective operations, message passing libraries, checkpointing, and operating systems. Topics covered: Speedup, Efficiency, Isoefficiency, Redundancy, Amdahls law, Computer Architecture Concepts, Parallel Machine Designs, Benmarks, Parallel Programming concepts & design, Algorithms, Parallel applications. This authoritative reference will be published in two formats: print and online. The online edition features hyperlinks to cross-references and to additional significant research. Related Subjects: supercomputing, high-performance computing, distributed computing

Author : Alena Pance ,Gabriel Rinaldi
Publisher : Frontiers Media SA
Page : 177 pages
File Size : 51,6 Mb
Release : 2024-05-15
Category : Science
ISBN : 9782832549070

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Stem Cell Technologies meet Stem Cell Biology to Shine New Light into Tropical Infectious Diseases by Alena Pance ,Gabriel Rinaldi Pdf

The aim of this collection of articles is to assemble advances in stem cell-based approaches and their application to the study of parasitic diseases. Tropical parasites, including unicellular protozoan organisms and helminths, represent a major public health burden, particularly in tropical regions of the world. The study of these organisms is significantly hampered by the lack of effective in vitro/ ex vivo culture systems that mimic natural conditions and facilitate a thorough understanding of parasite development and host-parasite interactions. The advent of stem cell technology offers the opportunity to derive the right cell types to culture these parasites. Moreover, stem cell-derived organoids accurately reproduce the particular niche in which the parasites grow, develop, interact with host tissues and reproduce. In addition, particularly for helminths (i.e., multicellular parasites), the identification and characterisation of the parasite’s stem cell system, will be critical to complement our current and future understanding of fundamental biological processes, such as worm maturation, and interaction with the host immune system and microbiota.

Author : Gary Stephens
Publisher : Springer Nature
Page : 540 pages
File Size : 54,9 Mb
Release : 2024-05-22
Category : Electronic
ISBN : 9783031521973

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Ion Channels as Targets in Drug Discovery by Gary Stephens Pdf

Author : Anonim
Publisher : Unknown
Page : 388 pages
File Size : 43,7 Mb
Release : 1993
Category : Electromagnetic theory
ISBN : UCSD:31822009014549

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Computational Electromagnetics and Supercomputer Architecture by Anonim Pdf