Isotopic Tracers In Biology

Author : Martin D. Kamen
Publisher : Elsevier
Page : 491 pages
File Size : 47,7 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483274331

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Isotopic Tracers in Biology by Martin D. Kamen Pdf

Isotopic Tracers in Biology: An Introduction to Tracer Methodology, Third Edition focuses on stable isotopes, structures, composition, and reactions of nitrogen and oxygen, and radioactive tracers. The book first takes a look at atomic nuclei, radioactivity, and the production of radioactive isotopes and radiation characteristics of tracer atoms. Topics include nuclear reactions, general properties of nuclei, radioactivity, target techniques and radiochemistry, and beta and gamma radiations. The text also discusses isotopic assay, radiation hazards, procedures related with sample preparation for radioactive assay, and combustion of labeled materials. The manuscript examines the biochemical, physiological, and medical aspects of tracer methodology, as well as biochemical applications, value of tracer methods for biology, intermediary metabolism, and applications to clinical research. The text also ponders on the isotopes of hydrogen, carbon, oxygen, nitrogen, phosphorus, and sulfur. Concerns include assay of deuterium and tritium, short-lived and heavy stable carbon, and oxygen, nitrogen, sulfur, and phosphorus isotopes. The publication is a dependable reference for readers interested in isotopic tracers.

Author : Anonim
Publisher : Unknown
Page : 474 pages
File Size : 44,7 Mb
Release : 1957
Category : Electronic
ISBN : OCLC:636804887

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Isotopic Tracers in Biology by Anonim Pdf

Author : Martin David Kamen
Publisher : Unknown
Page : 478 pages
File Size : 42,5 Mb
Release : 1959
Category : Tracers (Biology)
ISBN : OCLC:27421403

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Isotopic Tracers in Biology by Martin David Kamen Pdf

Author : Martin David Kamen
Publisher : Unknown
Page : 0 pages
File Size : 45,6 Mb
Release : 1957
Category : Isotopos
ISBN : LCCN:51009749

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Isotopic tracers in biology by Martin David Kamen Pdf

Author : Martin David Kamen
Publisher : Unknown
Page : 458 pages
File Size : 52,8 Mb
Release : 1951
Category : Biology
ISBN : UCAL:B3375420

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Radioactive Tracers in Biology by Martin David Kamen Pdf

Author : Shanmugasundaram Ganapathy-Kanniappan
Publisher : Springer Nature
Page : 76 pages
File Size : 49,8 Mb
Release : 2022-05-03
Category : Science
ISBN : 9783030997007

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Isotopic Tracer Techniques in Preclinical Research by Shanmugasundaram Ganapathy-Kanniappan Pdf

This book serves as a practical guide and a manual on the application of isotopic tracers in understanding the cellular processes (e.g. molecular interactions, protein synthesis) in growth, development, and disease conditions. The techniques described in the book have been carefully chosen to underscore the role and relevance of isotopic tracers in the identification of molecular targets and mechanisms, and preclinical validation of potential therapeutics. This book is intended to be a valuable resource to non-experts that may include students, researchers, educators/teachers, and others who have an interest to understand the application of isotopic tracers in research. Each chapter includes a background, an outline of the method and underlying principles, and a detailed step-wise protocol. To augment the clarity and intellectual grasp, the chapters also include relevant illustrations and study questions. More importantly, the book covers techniques involving radioactive as well as non-radioactive tracers to expand the scope of isotopes in preclinical research including basic and applied science.

Author : William E. Siri
Publisher : Unknown
Page : 678 pages
File Size : 45,7 Mb
Release : 1949
Category : Radioactive tracers in biology
ISBN : UOM:39015003385211

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Isotopic Tracers and Nuclear Radiations by William E. Siri Pdf

Author : George Wolf
Publisher : Elsevier
Page : 184 pages
File Size : 53,6 Mb
Release : 2013-09-24
Category : Science
ISBN : 9781483225746

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Isotopes in Biology by George Wolf Pdf

Isotope is Biology is a six-chapter supplementary text that covers the properties and application of isotopes as labels or analytical tools in biological research. The first chapters deal with the physico-chemical properties and radioactivity of isotopes. These chapters also explore their synthesis, preparation, radiation decomposition, and decay of radioactivity. The succeeding chapter considers other aspects of isotopes, including their effect of health, disposal, spills, and laboratory use. Another chapter examines the chemical and biochemical behavior, natural abundance, and the chemical stability of isotopic compounds. The final chapters describe several isotopic methods, namely, isotope dilution, paper chromatography, and autoradiography, with emphasis on their application in biological studies. This book will be of value to biologists, and graduate and undergraduate biology students.

Author : Martin D. Kamen
Publisher : Unknown
Page : 281 pages
File Size : 48,7 Mb
Release : 1948
Category : Electronic
ISBN : OCLC:760033299

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Radioactive Tracers in Biology by Martin D. Kamen Pdf

Author : G. E. Francis
Publisher : Unknown
Page : 556 pages
File Size : 44,9 Mb
Release : 1959
Category : Biology
ISBN : UOM:39015004357755

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Isotopic Tracers by G. E. Francis Pdf

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 54,5 Mb
Release : 1947
Category : Electronic
ISBN : OCLC:636804895

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Radioactive Tracers in Biology by Anonim Pdf

Author : Robert R. Wolfe
Publisher : Unknown
Page : 312 pages
File Size : 55,5 Mb
Release : 1984
Category : Medical
ISBN : UOM:39015006719325

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Tracers in Metabolic Research by Robert R. Wolfe Pdf

Methods for studying metabolism. Determination of substrate kinetics. Constant isotope infusion technique. Determination of substrate kinetics. Bolus-injection technique. Determination of substrate oxidation. Bicarbonate kinetics and natural enrichment. Priming the pool. Nonsteady state kinetics. Selection of sites for infusing isotope andj drawing samples. Specific application. Glucose metabolism. Specific application. Urea. Specific application. Fat meltabolism. Amino acids. Whole-body protein turnover. Total body water. Clinical application of stable isotopes. Analytical methods. Instrumentation. Mass spectrometry. Selected ion monitoring. Preparation of samples. Chromatography. Determination of specific radioactivity. Collection of CO2. Isotope ratio mass spectrometry techniques. Gas chromatography-mass spectrometry methods. In vivo approaches. Isotopic tracers. Advantages of stable isotopes. Biological effects. Enzymatic effects. Definition of terms. Influence of uptake on calculation of rate of appearance. Influence of pool size and complexity. Net movement of tracer and tracee. Clearance. Stable versus radioisotopes. Single-pool analysis. Bicarbonate recovery. Natural abundance of 13C. Practical consideration of performing recovery studies. Determining NaH13 CO3 infusion rate. Determining VCO2. Theory of priming dose. Priming secondary pools. Steele equation. In vivo assessment of steele equation. Glucose. Effective volume of distribution. Urea. Arterial versus central venous infusion.

Author : David Wright Wilson
Publisher : Unknown
Page : 132 pages
File Size : 40,5 Mb
Release : 1946
Category : Science
ISBN : UOM:39015004460120

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Preparation and Measurement of Isotopic Tracers by David Wright Wilson Pdf

Author : Brian Fry
Publisher : Springer Science & Business Media
Page : 308 pages
File Size : 44,7 Mb
Release : 2007-01-15
Category : Science
ISBN : 9780387337456

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Stable Isotope Ecology by Brian Fry Pdf

A solid introduction to stable isotopes that can also be used as an instructive review for more experienced researchers and professionals. The book approaches the use of isotopes from the perspective of ecological and biological research, but its concepts can be applied within other disciplines. A novel, step-by-step spreadsheet modeling approach is also presented for circulating tracers in any ecological system, including any favorite system an ecologist might dream up while sitting at a computer. The author’s humorous and lighthearted style painlessly imparts the principles of isotope ecology. The online material contains color illustrations, spreadsheet models, technical appendices, and problems and answers.

Author : Robert R. Wolfe,David L. Chinkes
Publisher : John Wiley & Sons
Page : 494 pages
File Size : 53,5 Mb
Release : 2004-10-18
Category : Medical
ISBN : 0471462098

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Isotope Tracers in Metabolic Research by Robert R. Wolfe,David L. Chinkes Pdf

In the past few years, the number of applications of tracers for in vivo biomedical studies has greatly increased. New analytical tools at the genetic and protein levels have spurred this growth, opening the door for a deeper understanding of metabolic events. This in turn promises to yield significant advances in the understanding and treatment of human disease. Now fully revised and expanded, Isotope Tracers in Metabolic Research, Second Edition is the established definitive text on stable and radioactive isotope tracers. In unique, multidisciplinary fashion, it presents comprehensive coverage of new methodological, mathematical, and theoretical approaches. This new Second Edition includes: All-new chapters on nuclear magnetic resonance, mass isotopomer analysis, and methods of protein metabolism analysis A completely updated categorized list of over 750 references Major advances in the development of mass isotopomer and positional isotopomer techniques, noninvasive isotope techniques for studying metabolic pathways, hyphenated techniques, and new tracer techniques The latest developments in quantification of DNA synthesis and mass spectrometry spurred by genome sequencing and proteomics New coverage of mathematical modeling Expanded coverage of microdialysis probes, laboratory procedures, and regulatory issues related to human studies In this complete guide to performing tracer studies, the authors systematically cover tracer selection, modeling considerations, sample derivitization, mass spectrometry analysis, and data interpretation. Problems and discussion questions highlight key points in each chapter. Isotope Tracers in Metabolic Research, Second Edition offers students and researchers a comprehensive, practical resource for utilizing the latest tracer methodologies.