Ivermectin And Abamectin

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Ivermectin and Abamectin

Author : William C. Campbell
Publisher : Springer Science & Business Media
Page : 380 pages
File Size : 42,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461236269

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Ivermectin and Abamectin by William C. Campbell Pdf

Ivermectin and abamectin, members of the avermectin family of compounds, were introduced to the market in the 1980's as a veterinary antiparasitic drug and agricultural pesticide, respectively. Their acceptance and commercial success have been remarkable; both are highly effective and in worldwide use. The efficacy of ivermectin in river blindness has expanded the interest in its use in human medicine. In response to the intense scientific and industrial interest in ivermectin and abamectin and the likelihood that they will be forerunners of an expanding family of drugs, this comprehensive monograph satisfies the need for a review and synthesis of current knowledge about the use of these substances in crop protection as well as in cattle, sheep, swine, horses, dogs, cats, birds, fish, reptiles, and in man. This overview presents chemical, biochemical, and microbiological data, as well as pharmacological, safety, and environmental aspects and covers practical use of the compounds as antiparasitic and pesticide agents, as well as the available safety data that have emerged from the clinical experience with human applications.

Insecticides with Novel Modes of Action

Author : Isaac Ishaaya,Danny Degheele
Publisher : Springer Science & Business Media
Page : 289 pages
File Size : 42,7 Mb
Release : 2013-06-29
Category : Technology & Engineering
ISBN : 9783662035658

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Insecticides with Novel Modes of Action by Isaac Ishaaya,Danny Degheele Pdf

The future of insect control looked very bright in the 1950s and 1960s with new insecticides constantly coming onto the market. Today, however, whole classes of pesticide chemistry have fallen by the wayside due to misuse which generated resistance problems reaching crisis proportions, severe adverse effects on the environment, and public outcry that has led to increasingly stricter regulation and legislation. It is with this background, demanding the need for safer, environmentally friendly pesticides and new strategies to reduce resistance problems, that this book was written. The authors of the various chapters have a wealth of experience in pesticide chemistry, biochemical modes of action, mechanism of resistance and application, and have presented concise reviews. Each is actively involved in thedevelopment of new groups of pesticide chemistry which led to the development of novel insecticides with special impact in controlling agricultural pests. Emphasis has been given to insecticides with selective properties, such as insect growth regulators hormone mimics, ecdysone agonists), (chitin synthesis inhibitors, juvenile chloronicotinyl insecticides (imidacloprid, acetamiprid), botanical insecticides (neem, plant oils), pymetrozine, diafenthiuron, pyrrole insecticides, and others. The importance of these compounds, as components in integrated pest management programs and in insecticide resistance management strategies, is discussed. The data presented are essential in establishing new technologies and developing novel groups of compounds which will have impact on our future agricultural practices.

Quantitative Structure-Activity Relationships (QSAR) for Pesticide Regulatory Purposes

Author : Anonim
Publisher : Elsevier
Page : 533 pages
File Size : 51,8 Mb
Release : 2011-10-13
Category : Science
ISBN : 9780080475325

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Quantitative Structure-Activity Relationships (QSAR) for Pesticide Regulatory Purposes by Anonim Pdf

Quantitative Structure-Activity Relationship (QSAR) for Pesticide Regulatory Purposes stems from the experience of the EC funded project DEMETRA. This project combined institutes involved in the regulatory process of pesticides, industries of the sector and scientists to develop and offer original software for the prediction of ecotoxicity of pesticides. Then to be used within the dossier preparation for pesticide registration. The basis of this book is more than three-years of research activities, discussions, studies and successful models. This experience represents a useful example not only for the case of pesticides, but also for the prediction of ecotoxicity and toxicity in general. QSAR is used to link a given property of a chemical compound with some features related to its structure. The theoretical toxicological, chemical and information technology aspects will be treated considering the regulatory issues. Innovative hybrid systems will be described, for the toxicity prediction of pesticides and related compounds, directly useful for pesticide evaluation within the Dossier preparation for pesticide registration. Five endpoints will also be discussed, addressing issues as standardisation, verification, validation, accessibility, reproducibility. The driving force for Quantitative Structure-Activity Relationship (QSAR) for Pesticide Regulatory Purposes is that all the issues of concern for end-users are analysed, discussed and solutions proposed further. An innovative feature is that, in order to offer powerful QSAR models, the book discusses and reports on integrated QSAR models, combined into a unique hybrid system. * Assesses the needs of regulators for pesticide approval and how these needs affect QSAR models * Combines theoretical discussion with practical examples, including five worked examples of hybrid systems * Refers to original software available through the internet

Approaches to Design and Synthesis of Antiparasitic Drugs

Author : N. Anand,S. Sharma†
Publisher : Elsevier
Page : 525 pages
File Size : 49,7 Mb
Release : 1997-07-10
Category : Medical
ISBN : 9780080527529

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Approaches to Design and Synthesis of Antiparasitic Drugs by N. Anand,S. Sharma† Pdf

This book presents a comprehensive and up to date account of the chemotherapy of parasitic diseases, both human and veterinary. The book starts with an overview of parasitic diseases. The body of the book is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. Both parts start with chapters highlighting the 'biochemical targets' available for chemotherapeutic interference. Individual chapters deal with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and methods of synthesis and their status both in clinical and veterinary practice. The book will be useful to a wide spectrum of readers: students embarking on a research career in parasitic chemotherapy, clinicians (and veterinarians) and clinical pharmacologists desiring detailed information about the drugs currently in use, and pharmaceutical technologists wanting to update their knowledge of the methods of manufacture.

Clinical Veterinary Toxicology - E-Book

Author : Konnie Plumlee
Publisher : Elsevier Health Sciences
Page : 504 pages
File Size : 48,6 Mb
Release : 2003-12-10
Category : Medical
ISBN : 9780323058346

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Clinical Veterinary Toxicology - E-Book by Konnie Plumlee Pdf

This book covers all aspects of toxicology, including toxic diseases of large animals, small animals, and exotic pets. It provides key information on how poisons affect the body, how the body responds to a foreign substance, how poisonings are diagnosed, and how poisonings are treated. Coverage includes every organ system of every species of animal with details on each body system's susceptibility to poison. Poisons affect animals differently depending on species, breed, age, gender, health status, and reproductive status. This resource addresses these differences, allowing the veterinarian to determine the class of toxicant, the mechanism of action, and the proper course of treatment. If confronted with an unknown poison, the information in this book will assist the veterinarian in formulating a list of potential poisons based on the clinical signs that the animal is exhibiting, and in choosing the appropriate tests to narrow the list to one or a few possible poisons. Most comprehensive toxicology book available Written in a user-friendly style that makes it easy to master the content Covers poisonings in both large and small domestic animals The Principles of Toxicology section provides comprehensive coverage of concepts & terminology, toxicokinetics, treatments, and regulatory information The Manifestations of Toxicoses section is devoted to differentiating between poisons based on lesions and clinical signs The Classes of Toxicants section offers detailed information on each poison, including sources, risk factors, pathophysiology, clinical signs and lesions, diagnostic testing, and treatment The author is board-certified in toxicology, and the contributors are all toxicologists and educators, ensuring authoritative, up-to-date clinical information

Hayes' Handbook of Pesticide Toxicology

Author : Anonim
Publisher : Academic Press
Page : 2407 pages
File Size : 53,9 Mb
Release : 2010-02-15
Category : Medical
ISBN : 9780080922010

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Hayes' Handbook of Pesticide Toxicology by Anonim Pdf

The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book’s tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition. Feature: Presents a comprehensive look at all aspects of pesticide toxicology in one reference work. Benefit: Saves researchers time in quickly accessing the very latest definitive details on toxicity of specific pesticides as opposed to searching through thousands of journal articles. Feature: Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions Benefit: Connects the experimental laboratory results to real-life applications in human health, animal health and the environment. Feature: All major classes of pesticide considered. Benefit: Provides relevance to a wider variety of researchers who are conducting comparative work in pesticides or their health impacts. Feature: Different routes of exposure critically evaluated. Benefit: Connects the loop between exposure and harmful affects to those who are researching the affects of pesticides on humans or wildlife.

Public Health Significance of Urban Pests

Author : Xavier Bonnefoy,Helge Kampen,Kevin Sweeney
Publisher : World Health Organization
Page : 293 pages
File Size : 54,8 Mb
Release : 2008
Category : Medical
ISBN : 9789289071888

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Public Health Significance of Urban Pests by Xavier Bonnefoy,Helge Kampen,Kevin Sweeney Pdf

The second half of the 20th century and the beginning of the 21st century witnessed important changes in ecology, climate and human behaviour that favoured the development of urban pests. Most alarmingly, urban planners now face the dramatic expansion of urban sprawl, in which city suburbs are growing into the natural habitats of ticks, rodents and other pests. Also, many city managers now erroneously assume that pest-borne diseases are relics of the past. All these changes make timely a new analysis of the direct and indirect effects of present-day urban pests on health. Such an analysis should lead to the development of strategies to manage them and reduce the risk of exposure. To this end, WHO invited international experts in various fields - pests, pest-related diseases and pest management - to provide evidence on which to base policies. These experts identified the public health risk posed by various pests and appropriate measures to prevent and control them. This book presents their conclusions and formulates policy options for all levels of decision-making to manage pests and pest-related diseases in the future. [Ed.]

Diseases of The Goat

Author : John G. Matthews
Publisher : John Wiley & Sons
Page : 472 pages
File Size : 46,5 Mb
Release : 2016-09-26
Category : Medical
ISBN : 9781119073512

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Diseases of The Goat by John G. Matthews Pdf

Diseases of the Goat, 4th Edition, is a revised and updated edition of the popular tool for veterinarians featuring of all aspects of goat medicine—from initial assessment and examination to diagnosis, treatment, and control of conditions. This highly practical, concise handbook is designed for frequent reference, and is suitable for all those treating and keeping goats. Provides information on to predators, euthanasia, post-mortem technique, and fracture repair Includes expanded coverage of a number of topics to appeal to a wider and more international audience especially in relation to poisonous plants Incorporates the impact of new developments in goat diseases, such as the geographical spread of exotic diseases into new regions

Macrocyclic Lactones in Antiparasitic Therapy

Author : Robert S. Rew
Publisher : CABI
Page : 432 pages
File Size : 50,5 Mb
Release : 2002-01-01
Category : Medical
ISBN : 0851996175

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Macrocyclic Lactones in Antiparasitic Therapy by Robert S. Rew Pdf

"A previous book published in 1989 provided a comprehensive view of one of the macrocyclic lactones. The present book updates previous information and expands to provide new information generated on the entire class of compounds together with detailed coverage of the basic science of these drugs and their mode of action, as well as their clinical use in farm and companion animals and in humans. The contents include chemistry and mode of action, pharmacology, toxicology, ecology and efficacy, use in large and small animals and in humans, and resistance against macrocyclic lactones. The book will be of interest to those working within the areas of parasitology, pharmacology, and veterinary and human medicine."--BOOK JACKET.

Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose

Author : Michael W. Shannon,Stephen W. Borron,Michael J. Burns (MD.),Lester M. Haddad,James F. Winchester
Publisher : Saunders
Page : 0 pages
File Size : 52,9 Mb
Release : 2007
Category : Drugs
ISBN : 0721606938

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Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose by Michael W. Shannon,Stephen W. Borron,Michael J. Burns (MD.),Lester M. Haddad,James F. Winchester Pdf

This edition is a reference for information related to the clinical management of children and adults whose health has been effected or potentially effected by toxic agents, including drugs, environmental threats, and natural toxins.

Pyrantel Parasiticide Therapy in Humans and Domestic Animals

Author : Alan A Marchiondo
Publisher : Academic Press
Page : 0 pages
File Size : 55,9 Mb
Release : 2016-06-03
Category : Medical
ISBN : 0128014490

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Pyrantel Parasiticide Therapy in Humans and Domestic Animals by Alan A Marchiondo Pdf

Pyrantel Parasiticide Therapy in Humans and Domestic Animals presents a single source history and reference on the parasiticide activity and pharmacology of the tetrahydropyrimidines and their salts in humans and domestic animals, also collating evidence that resistance to pyrantel has developed in human and domestic animal nematodes. Other books of this nature have been compiled historically for specific anthelmintic compounds, but none has been written to date for the pyrantel family of drugs. Pyrantel, a nicotinic receptor agonist, has been used in domestic animal and human medicine since the 1970's to control two important nematode groups, the hookworms and the roundworms. Given the zoonotic potential of these parasites, pyrantel has served a dual role in helping to protect the health of both domestic animals and the public for more than 45 years.

Natural Bioactive Products in Sustainable Agriculture

Author : Joginder Singh,Ajar Nath Yadav
Publisher : Springer Nature
Page : 307 pages
File Size : 53,6 Mb
Release : 2020-05-11
Category : Medical
ISBN : 9789811530241

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Natural Bioactive Products in Sustainable Agriculture by Joginder Singh,Ajar Nath Yadav Pdf

This book discusses various aspects of bioactive natural products employed in the agrochemical and agriculture sectors. It covers the use of plants, microorganisms, and microbial metabolites as eco-friendly, cost-effective, and sustainable alternatives to chemicals in the field of agriculture. Written by active researchers and academics, the book highlights state-of-art products in the field, as well as the gaps, challenges, and obstacles associated with the use of plants, microbes and their products. Given its scope, it is a valuable resource for the scientific community and professionals in enterprises wanting insights into the latest developments and advances in the context of biological products, including their applications, traditional uses, modern practices, and strategies to harness their full potential.

Synthesis of Best-Seller Drugs

Author : Ruben Vardanyan,Victor Hruby
Publisher : Academic Press
Page : 868 pages
File Size : 42,7 Mb
Release : 2016-01-07
Category : Science
ISBN : 9780124115248

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Synthesis of Best-Seller Drugs by Ruben Vardanyan,Victor Hruby Pdf

Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation

Toxicological Evaluation of Certain Veterinary Drug Residues in Food

Author : Joint FAO/WHO Expert Committee on Food Additives,Joint FAO/WHO Expert Committee on Food Additives. Meeting
Publisher : World Health Organization
Page : 206 pages
File Size : 55,5 Mb
Release : 2005
Category : Business & Economics
ISBN : 9241660538

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Toxicological Evaluation of Certain Veterinary Drug Residues in Food by Joint FAO/WHO Expert Committee on Food Additives,Joint FAO/WHO Expert Committee on Food Additives. Meeting Pdf

The monographs in this volume summarize data on the veterinary drug residues that were evaluated toxicologically by the Committee, which included three antimicrobial agents (cefuroxime, flumequine and pirlimycin), two insecticides (cyhalothrin, and cypermethrin and alpha-cypermethrin) and one production aid (ractopamine). The Committee also evaluated the safety of low levels of the antimicrobial agent chloramphenicol in animal products. This volume and others in the WHO Food Additives Series contain information that is useful to those who produce and use food additives and veterinary drugs and those involved with controlling contaminants in food, government and food regulatory officers, industrial testing laboratories, toxicological laboratories, and universities.

Pesticide Chemistry and Bioscience

Author : G. T. Brooks,T. Roberts
Publisher : Elsevier
Page : 438 pages
File Size : 55,9 Mb
Release : 1999-01-01
Category : Technology & Engineering
ISBN : 9781845698416

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Pesticide Chemistry and Bioscience by G. T. Brooks,T. Roberts Pdf

This volume, with contributions from leading international experts, reports on the need to produce high quality food whilst satisfying environmental concerns. Including material on natural products, modes of action and metabolism, it covers all the key areas in pesticide chemistry and related activities. The contents outline the developments that have taken place in approaches to crop protection and our ability to develop complex, environmentally acceptable strategies for weed, pest and disease control.