Labs On Chip

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Labs on Chip

Eugenio Iannone
Labs on Chip Book PDF

Author : Eugenio Iannone
Publisher : CRC Press
Page : 1178 pages
File Size : 42,5 Mb
Release : 2018-09-03
Category : Medical
ISBN : 9781466560734

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Labs on Chip by Eugenio Iannone Pdf

Labs on Chip: Principles, Design and Technology provides a complete reference for the complex field of labs on chip in biotechnology. Merging three main areas— fluid dynamics, monolithic micro- and nanotechnology, and out-of-equilibrium biochemistry—this text integrates coverage of technology issues with strong theoretical explanations of design techniques. Analyzing each subject from basic principles to relevant applications, this book: Describes the biochemical elements required to work on labs on chip Discusses fabrication, microfluidic, and electronic and optical detection techniques Addresses planar technologies, polymer microfabrication, and process scalability to huge volumes Presents a global view of current lab-on-chip research and development Devotes an entire chapter to labs on chip for genetics Summarizing in one source the different technical competencies required, Labs on Chip: Principles, Design and Technology offers valuable guidance for the lab-on-chip design decision-making process, while exploring essential elements of labs on chip useful both to the professional who wants to approach a new field and to the specialist who wants to gain a broader perspective.

Lab-on-a-Chip Fabrication and Application

Margarita Stoytcheva,Roumen Zlatev
Lab on a Chip Fabrication and Application Book PDF

Author : Margarita Stoytcheva,Roumen Zlatev
Publisher : BoD – Books on Demand
Page : 210 pages
File Size : 50,6 Mb
Release : 2016-06-29
Category : Science
ISBN : 9789535124573

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Lab-on-a-Chip Fabrication and Application by Margarita Stoytcheva,Roumen Zlatev Pdf

The necessity of on-site, fast, sensitive, and cheap complex laboratory analysis, associated with the advances in the microfabrication technologies and the microfluidics, made it possible for the creation of the innovative device lab-on-a-chip (LOC), by which we would be able to scale a single or multiple laboratory processes down to a chip format. The present book is dedicated to the LOC devices from two points of view: LOC fabrication and LOC application.

Error-Tolerant Biochemical Sample Preparation with Microfluidic Lab-on-Chip

Sudip Poddar,Bhargab B. Bhattacharya
Error Tolerant Biochemical Sample Preparation with Microfluidic Lab on Chip Book PDF

Author : Sudip Poddar,Bhargab B. Bhattacharya
Publisher : CRC Press
Page : 240 pages
File Size : 42,5 Mb
Release : 2022-07-27
Category : Technology & Engineering
ISBN : 9781000612738

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Error-Tolerant Biochemical Sample Preparation with Microfluidic Lab-on-Chip by Sudip Poddar,Bhargab B. Bhattacharya Pdf

Microfluidic biochips have gained prominence due to their versatile applications to biochemistry and health-care domains such as point-of-care clinical diagnosis of tropical and cardiovascular diseases, cancer, diabetes, toxicity analysis, and for the mitigation of the global HIV crisis, among others. Microfluidic Lab-on-Chips (LoCs) offer a convenient platform for emulating various fluidic operations in an automated fashion. However, because of the inherent uncertainty of fluidic operations, the outcome of biochemical experiments performed on-chip can be erroneous even if the chip is tested a priori and deemed to be defect-free. This book focuses on the issues encountered in reliable sample preparation with digital microfluidic biochips (DMFBs), particularly in an error-prone environment. It presents state-of-the-art error management techniques and underlying algorithmic challenges along with their comparative discussions. Describes a comprehensive framework for designing a robust and error-tolerant biomedical system which will help in migrating from cumbersome medical laboratory tasks to small-sized LOC-based systems Presents a comparative study on current error-tolerant strategies for robust sample preparation using DMFBs and reports on efficient algorithms for error-tolerant sample dilution using these devices Illustrates how algorithmic engineering, cyber-physical tools, and software techniques are helpful in implementing fault tolerance Covers the challenges associated with design automation for biochemical sample preparation Teaches how to implement biochemical protocols using software-controlled microfluidic biochips Interdisciplinary in its coverage, this reference is written for practitioners and researchers in biochemical, biomedical, electrical, computer, and mechanical engineering, especially those involved in LOC or bio-MEMS design.

Lab-on-a-Chip Devices and Micro-Total Analysis Systems

Jaime Castillo-León,Winnie E. Svendsen
Lab on a Chip Devices and Micro Total Analysis Systems Book PDF

Author : Jaime Castillo-León,Winnie E. Svendsen
Publisher : Springer
Page : 243 pages
File Size : 53,7 Mb
Release : 2014-11-05
Category : Technology & Engineering
ISBN : 9783319086873

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Lab-on-a-Chip Devices and Micro-Total Analysis Systems by Jaime Castillo-León,Winnie E. Svendsen Pdf

This book covers all the steps in order to fabricate a lab-on-a-chip device starting from the idea, the design, simulation, fabrication and final evaluation. Additionally, it includes basic theory on microfluidics essential to understand how fluids behave at such reduced scale. Examples of successful histories of lab-on-a-chip systems that made an impact in fields like biomedicine and life sciences are also provided. This book also: · Provides readers with a unique approach and toolset for lab-on-a-chip development in terms of materials, fabrication techniques, and components · Discusses novel materials and techniques, such as paper-based devices and synthesis of chemical compounds on-chip · Covers the four key aspects of development: basic theory, design, fabrication, and testing · Provides readers with a comprehensive list of the most important journals, blogs, forums, and conferences where microfluidics and lab-on-a-chip news, methods, techniques and challenges are presented and discussed, as well as a list of companies providing design and simulation support, components, and/or developing lab-on-a-chip and microfluidic devices.

Lab-on-a-chip

Yehya H. Ghallab,Wael Badawy
Lab on a chip Book PDF

Author : Yehya H. Ghallab,Wael Badawy
Publisher : Artech House
Page : 239 pages
File Size : 43,6 Mb
Release : 2010
Category : Biomedical engineering
ISBN : 9781596934191

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Lab-on-a-chip by Yehya H. Ghallab,Wael Badawy Pdf

HereOCOs a groundbreaking book that introduces and discusses the important aspects of lab-on-a-chip, including the practical techniques, circuits, microsystems, and key applications in the biomedical, biology, and life science fields. Moreover, this volume covers ongoing research in lab-on-a-chip integration and electric field imaging. Presented in a clear and logical manner, the book provides you with the fundamental underpinnings of lab-on-a-chip, presents practical results, and brings you up to date with state-of-the-art research in the field. This unique resource is supported with over 160 illustrations that clarify important topics throughout.

Medical Biosensors for Point of Care (POC) Applications

Roger J Narayan
Medical Biosensors for Point of Care POC Applications Book PDF

Author : Roger J Narayan
Publisher : Woodhead Publishing
Page : 316 pages
File Size : 48,9 Mb
Release : 2016-08-21
Category : Medical
ISBN : 9780081000786

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Medical Biosensors for Point of Care (POC) Applications by Roger J Narayan Pdf

Medical Biosensors for Point of Care (POC) Applications discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care. Part 1 covers the fundamentals of medical biosensors for point-of-care applications. Chapters in part 2 go on to look at materials and fabrication of medical biosensors while the next part looks at different technologies and operational techniques. The final set of chapters provide an overview of the current applications of this technology. Traditionally medical diagnostics have been dependent on sophisticated technologies which only trained professionals were able to operate. Recent research has focused on creating point-of-care diagnostic tools. These biosensors are miniaturised, portable, and are designed to be used at the point-of-care by untrained individuals, providing real-time and remote health monitoring. Provides essential knowledge for designers and manufacturers of biosensors for point-of-care applications Provides comprehensive coverage of the fundamentals, materials, technologies, and applications of medical biosensors for point-of-care applications Includes contributions from leading international researchers with extensive experience in developing medical biosensors Discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care

Lab-on-Fiber Technology

Andrea Cusano,Marco Consales,Alessio Crescitelli,Armando Ricciardi
Lab on Fiber Technology Book PDF

Author : Andrea Cusano,Marco Consales,Alessio Crescitelli,Armando Ricciardi
Publisher : Springer
Page : 359 pages
File Size : 44,8 Mb
Release : 2014-07-29
Category : Technology & Engineering
ISBN : 9783319069982

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Lab-on-Fiber Technology by Andrea Cusano,Marco Consales,Alessio Crescitelli,Armando Ricciardi Pdf

This book focuses on a research field that is rapidly emerging as one of the most promising ones for the global optics and photonics community: the “lab-on-fiber” technology. Inspired by the well-established "lab on-a-chip" concept, this new technology essentially envisages novel and highly functionalized devices completely integrated into a single optical fiber for both communication and sensing applications. Based on the R&D experience of some of the world's leading authorities in the fields of optics, photonics, nanotechnology, and material science, this book provides a broad and accurate description of the main developments and achievements in the lab-on-fiber technology roadmap, also highlighting the new perspectives and challenges to be faced. This book is essential for scientists interested in the cutting-edge fiber optic technology, but also for graduate students.

Microfluidics and Lab-on-a-Chip

Andreas Manz,Giuseppina Simone,Jonathan S. O'Connor,Pavel Neuzil
Microfluidics and Lab on a Chip Book PDF

Author : Andreas Manz,Giuseppina Simone,Jonathan S. O'Connor,Pavel Neuzil
Publisher : Royal Society of Chemistry
Page : 307 pages
File Size : 45,6 Mb
Release : 2020-09-24
Category : Science
ISBN : 9781782628330

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Microfluidics and Lab-on-a-Chip by Andreas Manz,Giuseppina Simone,Jonathan S. O'Connor,Pavel Neuzil Pdf

Responding to the need for an affordable, easy-to-read textbook that introduces microfluidics to undergraduate and postgraduate students, this concise book will provide a broad overview of the important theoretical and practical aspects of microfluidics and lab-on-a-chip, as well as its applications.

Electrokinetics in Microfluidics

Dongqing Li
Electrokinetics in Microfluidics Book PDF

Author : Dongqing Li
Publisher : Elsevier
Page : 653 pages
File Size : 50,7 Mb
Release : 2004-08-20
Category : Science
ISBN : 9780080530741

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Electrokinetics in Microfluidics by Dongqing Li Pdf

A lab-on-a-chip device is a microscale laboratory on a credit-card sized glass or plastic chip with a network of microchannels, electrodes, sensors and electronic circuits. These labs on a chip can duplicate the specialized functions as performed by their room-sized counterparts, such as clinical diagnoses, PCR and electrophoretic separation. The advantages of these labs on a chip include significant reduction in the amounts of samples and reagents, very short reaction and analysis time, high throughput and portability. Generally, a lab-on-a-chip device must perform a number of microfluidic functions: pumping, mixing, thermal cycling/incubating, dispensing, and separating. Precise manipulation of these microfluidic processes is key to the operation and performance of labs on a chip. The objective of this book is to provide a fundamental understanding of the interfacial electrokinetic phenomena in several key microfluidic processes, and to show how these phenomena can be utilised to control the microfluidic processes. For this purpose, this book emphasises the theoretical modelling and the numerical simulation of these electrokinetic phenomena in microfluidics. However, experimental studies of the electrokinetic microfluidic processes are also highlighted in sufficient detail. The first book which systematically reviews electrokinetic microfluidics processes for lab-on-a chip applications Covers modelling and numerical simulation of the electrokinetic microfluidics processes Providing information on experimental studies and details of experimental techniques, which are essential for those who are new to this field

Algorithms for Sample Preparation with Microfluidic Lab-on-Chip

Bhattacharjee, Sukanta,Bhattacharya, Bhargab B. ,Chakrabarty, Krishnendu
Algorithms for Sample Preparation with Microfluidic Lab on Chip Book PDF

Author : Bhattacharjee, Sukanta,Bhattacharya, Bhargab B. ,Chakrabarty, Krishnendu
Publisher : River Publishers
Page : 182 pages
File Size : 54,8 Mb
Release : 2019-02-05
Category : Technology & Engineering
ISBN : 9788770220552

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Algorithms for Sample Preparation with Microfluidic Lab-on-Chip by Bhattacharjee, Sukanta,Bhattacharya, Bhargab B. ,Chakrabarty, Krishnendu Pdf

Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip attempts to bridge the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips. Technical topics discussed in the book include: Basics of digital and flow-based microfluidic lab-on-chipComprehensive review of state-of-the-art sample preparation algorithmsSample-preparation algorithms for digital microfluidic lab-on-chipSample-preparation algorithms for flow-based microfluidic lab-on-chip

Nanosensor Technologies for Environmental Monitoring

Inamuddin,Abdullah M. Asiri
Nanosensor Technologies for Environmental Monitoring Book PDF

Author : Inamuddin,Abdullah M. Asiri
Publisher : Springer Nature
Page : 529 pages
File Size : 42,5 Mb
Release : 2020-07-15
Category : Science
ISBN : 9783030451165

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Nanosensor Technologies for Environmental Monitoring by Inamuddin,Abdullah M. Asiri Pdf

Advanced materials and nanotechnology is a promising, emerging field involving the use of nanoparticles to facilitate the detection of various physical and chemical parameters, including temperature, humidity, pH, metal ion, anion, small organic or inorganic molecules, gases, and biomolecules responsible for environmental issues that can lead to diseases like cancer, diabetes, osteoarthritis, bacterial infections, and brain, retinal, and cardiovascular diseases. By monitoring environmental samples and detecting these environmental issues, advanced nanotechnology in this type of sensory technology is able to improve daily quality of life. Although these sensors are commercially available for the detection of monovalent cations, anions, gases, volatile organic molecules, heavy metal ions, and toxic metal ions, many existing models require significant power and lack advanced technology for more quality selectivity and sensitivity. There is room in these sensors to optimize their selectivity, reversibility, on/off ratio, response time, and their environmental stability in real-world operating conditions. This book explores the methods for the development and design of environmentally-friendly, simple, reliable, and cost effective electrochemical nanosensors using powerful nanostructured materials. More specifically, it highlights the use of various electrochemical-based biosensor sensors involved in the detection of monovalent cations, anions, gases, volatile organic molecules, heavy metal ions, and toxic metal ions, with the ultimate goal of seeing these technologies reach market.

Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery

Paul C.H. Li
Microfluidic Lab on a Chip for Chemical and Biological Analysis and Discovery Book PDF

Author : Paul C.H. Li
Publisher : CRC Press
Page : 528 pages
File Size : 51,6 Mb
Release : 2005-11-01
Category : Science
ISBN : 9781420027457

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Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery by Paul C.H. Li Pdf

The microfluidic lab-on-a-chip allows scientists to conduct chemical and biochemical analysis in a miniaturized format so small that properties and effects are successfully enhanced, and processes seamlessly integrated. This microscale advantage translates into greater sensitivity, more accurate results, and better information. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery focuses on all aspects of the microfluidic lab-on-a-chip technologies and offers an overview of the available technology, its limitations, and its breakthroughs over the years. It emphasizes analytical applications of microfluidic technology and offers in-depth coverage of micromachining methods, microfluidic operations, chemical separations, sample preparation and injection methods, detection technology, and various chemical and biological analyses. Other topics of interest include the use of polymeric chips, fluid flow valve and control, single-cell analysis, DNA and RNA amplification techniques, DNA hybridization, immunoassays and enzymatic assays. Originally conceived as a single chapter published in Ewing's Analytical Instrumentation, this book is a gateway to the vast literature and conference proceedings on the topic. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery expands upon its roots to present a comprehensive treatment of microfluidic lab-on-a-chip methods and applications for novices and advanced researchers alike.

Lab on a Chip Technology: Fabrication and microfluidics

K. E. Herold,Keith E. Herold,Avraham Rasooly
Lab on a Chip Technology Fabrication and microfluidics Book PDF

Author : K. E. Herold,Keith E. Herold,Avraham Rasooly
Publisher : Caister Academic Press Limited
Page : 0 pages
File Size : 47,9 Mb
Release : 2009
Category : Science
ISBN : 1904455468

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Lab on a Chip Technology: Fabrication and microfluidics by K. E. Herold,Keith E. Herold,Avraham Rasooly Pdf

Theoretical and technical information on current LOC technologies, and the design and development of LOC systems, methods and applications.

The Idea Factory

Jon Gertner
The Idea Factory Book PDF

Author : Jon Gertner
Publisher : Penguin
Page : 432 pages
File Size : 40,6 Mb
Release : 2012-03-15
Category : Business & Economics
ISBN : 9781101561089

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The Idea Factory by Jon Gertner Pdf

The definitive history of America’s greatest incubator of innovation and the birthplace of some of the 20th century’s most influential technologies “Filled with colorful characters and inspiring lessons . . . The Idea Factory explores one of the most critical issues of our time: What causes innovation?” —Walter Isaacson, The New York Times Book Review “Compelling . . . Gertner's book offers fascinating evidence for those seeking to understand how a society should best invest its research resources.” —The Wall Street Journal From its beginnings in the 1920s until its demise in the 1980s, Bell Labs-officially, the research and development wing of AT&T-was the biggest, and arguably the best, laboratory for new ideas in the world. From the transistor to the laser, from digital communications to cellular telephony, it's hard to find an aspect of modern life that hasn't been touched by Bell Labs. In The Idea Factory, Jon Gertner traces the origins of some of the twentieth century's most important inventions and delivers a riveting and heretofore untold chapter of American history. At its heart this is a story about the life and work of a small group of brilliant and eccentric men-Mervin Kelly, Bill Shockley, Claude Shannon, John Pierce, and Bill Baker-who spent their careers at Bell Labs. Today, when the drive to invent has become a mantra, Bell Labs offers us a way to enrich our understanding of the challenges and solutions to technological innovation. Here, after all, was where the foundational ideas on the management of innovation were born.

Microfluidics and Multi Organs on Chip

P. V. Mohanan
Microfluidics and Multi Organs on Chip Book PDF

Author : P. V. Mohanan
Publisher : Springer Nature
Page : 712 pages
File Size : 47,7 Mb
Release : 2022-07-11
Category : Medical
ISBN : 9789811913792

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Microfluidics and Multi Organs on Chip by P. V. Mohanan Pdf

This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices. It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation, ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners.