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Law and Economics of Personalized Medicine by Karin Bosshard Pdf
The book adds to the discussion about strategic approaches towards the translation of personalized medicine into clinical practice. It stresses the importance of non-science related, institutional barriers. A Law and Economics perspective is applied in order to examine the incentives induced by the barriers. An applied part identifies and evaluates policy levers to foster the translation of personalized medicine into Swiss clinical practice.
Personalized Medicine in Healthcare Systems by Nada Bodiroga-Vukobrat,Daniel Rukavina,Krešimir Pavelić,Gerald G. Sander Pdf
This book gathers scientific contributions on comprehensive approaches to personalized medicine. In a systematic and clear manner, it provides extensive information on the methodological, technological, and clinical aspects of high-throughput analytics, nanotechnology approaches, microbiota/human interactions, in-vitro fertilization and preimplantation, and various diseases like cancer.Moreover, the book analyzes the social and legal aspects of social security systems, healthcare systems and EU law – e.g. the role of solidarity, regulatory possibilities and obstacles, justice and equality, privacy/disclosure of data, and the right to know – from an interdisciplinary perspective. Lastly, it explores the economical and ethical context in the fields of business models, intellectual property issues, the patient/physician relationship, and price discrimination.
Novel Perspectives in Economics of Personalized Medicine and Healthcare Systems by Romina Prziklas Druzeta,Marinko Škare,Sandra Kraljević Pavelić Pdf
"The book Novel Perspectives in Economics of Personalized Medicine and Healthcare Systems represents a valuable interdisciplinary contribution created to fill an existing gap in the field of health economics and healthcare systems. The book brings the latest insights from the growing field of health economics and healthcare systems. It deals with various economic, technological, sociological, ethical, legal and philosophical implications and questions arising from the development and implementation of personalized medicine. It is unprecedented in combining practical guidelines for the use of economic tools and techniques with an analysis of the current process of decision-making in the health service sector. The book also provides several insights into the factors that determine human health, the socioeconomic aspects of population aging and the social implications of the evolving burden of disease. Some contributions are highly innovative and cover extremely relevant branches of medicine such as oncology, neurology and endocrinology. In addition, in a brave, yet professional and sovereign manner, the book covers the issue of biological predictors of health outcomes; though they are currently mainly used as global analytical methods, they are yet to be applied or have only recently been applied in clinical medicine. Further, it provides an example from traditional Korean medicine, a proven and valuable tool for personalized medical healthcare. This edition is unique in the sense that 30 chapters were written by 41 authors, all of them experts in their respective fields of research. The authors hail from Croatia, Hungary, South Korea and the United States. The volume is intended to serve as valuable teaching material for university students, as well as a reference book for research scholars, policymakers, business executives, health managers, physicians and freelance readers"--
Personalized Medicine by Nada Bodiroga-Vukobrat,Daniel Rukavina,Krešimir Pavelić,Gerald G. Sander Pdf
This book offers comprehensive coverage of the various aspects of personalized medicine as an original approach to classifying, understanding, treating and preventing disease based on individual biological differences. In the introductory section, it defines personalized medicine as a way toward new medical practices and addresses the question: What can personalized medicine offer citizens, medical professionals, reimbursement bodies and stakeholders? Subsequent chapters discuss the technological aspects of personalized medicine: data collection, comprehensive integration and handling of data, together with key enabling factors in developing the requisite technological support for personalized medicine. Lastly, the book explores the main issues shaping the implementation and development of personalized medicine – education, stakeholder participation, infrastructure, a new approach to the classification of disease and medical tests, regulatory frameworks, and new reimbursement models – together with ethical, legal and social issues. Ultimately, the book calls for interdisciplinarity and a radical change in the way we approach the health and wellbeing of individuals. Target groups are medical doctors and researchers in the field of biomedicine, as well as experts from the social sciences dealing with legal, economic and social aspects of health system issues in general. Though the book will primarily benefit these groups of professional experts, its content will also appeal to a far wider readership, as it deals with a paradigm shift in one of society’s main pillars – the health system.
Author : Ernst R. Berndt,Dana P. Goldman,John Rowe Publisher : University of Chicago Press Page : 361 pages File Size : 50,7 Mb Release : 2019-04-22 Category : Business & Economics ISBN : 9780226611068
Economic Dimensions of Personalized and Precision Medicine by Ernst R. Berndt,Dana P. Goldman,John Rowe Pdf
Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.
Socio-economics of Personalized Medicine in Asia by Shirley Sun Pdf
The second decade of the twenty-first century has witnessed a surging interest in personalized medicine with the concomitant promise to enable more precise diagnosis and treatment of disease and illness, based upon an individual’s unique genetic makeup. In this book, my goal is to contribute to a growing body of literature on personalized medicine by tracing and analyzing how this field has blossomed in Asia. In so doing, I aim to illustrate how various social and economic forces shape the co-production of science and social order in global contexts. This book shows that there are inextricable transnational linkages between developing and developed countries and also provides a theoretically guided and empirically grounded understanding of the formation and usage of particular racial and ethnic human taxonomies in local, national and transnational settings. The Open Access version of this book, available at http://www.taylorfrancis.com/doi/view/10.4324/9781315537177 has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.
Personalized Medicine in the Making by Chiara Beneduce,Marta Bertolaso Pdf
This book offers a multidisciplinary look at the much-debated concept of “personalized medicine”. By combining a humanistic and a scientific approach, the book builds up a multidimensional way to understand the limits and potentialities of a personalized approach in medicine and healthcare. The book reflects on personalized medicine and complex diseases, the relationship between personalized medicine and the new bio-technologies, personalized medicine and personalized nutrition, and on some ethical, political, economic, and social implications of personalized medicine. This volume is of interest to researchers from several disciplines including philosophy, bio-medicine, and the social sciences. Chapter 16, “The Impact of Fantasy” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Textbook of Personalized Medicine by Kewal K. Jain Pdf
Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.
The Law and Economics of Privacy, Personal Data, Artificial Intelligence, and Incomplete Monitoring by James Langenfeld,Frank Fagan,Samuel Clark Pdf
The Law and Economics of Privacy, Personal Data, Artificial Intelligence, and Incomplete Monitoring showcases the cutting edge theoretical and empirical findings for researchers and professionals considering these complex issues intersecting law, technology, and economics.
Personalized Law by Omri Ben-Shahar,Ariel Porat Pdf
We live in a world of one-size-fits-all law. People are different, but the laws that govern them are uniform. "Personalized Law"---rules that vary person by person---will change that. Here is a vision of a brave new world, where each person is bound by their own personally-tailored law. "Reasonable person" standards would be replaced by a multitude of personalized commands, each individual with their own "reasonable you" rule. Skilled doctors would be held to higher standards of care, the most vulnerable consumers and employees would receive stronger protections, age restrictions for driving or for the consumption of alcohol would vary according the recklessness risk that each person poses, and borrowers would be entitled to personalized loan disclosures tailored to their unique needs and delivered in a format fitting their mental capacity. The data and algorithms to administer personalize law are at our doorstep, and embryos of this regime are sprouting. Should we welcome this transformation of the law? Does personalized law harbor a utopic promise, or would it produce alienation, demoralization, and discrimination? This book is the first to explore personalized law, offering a vision of law and robotics that delegates to machines those tasks humans are least able to perform well. It inquires how personalized law can be designed to deliver precision and justice and what pitfalls the regime would have to prudently avoid. In this book, Omri Ben-Shahar and Ariel Porat not only present this concept in a clear, easily accessible way, but they offer specific examples of how personalized law may be implemented across a variety of real-life applications.
Research Handbook on Socio-Legal Studies of Medicine and Health by Marie-Andrée Jacob,Anna Kirkland Pdf
This timely Research Handbook offers significant insights into an understudied subject, bringing together a broad range of socio-legal studies of medicine to help answer complex and interdisciplinary questions about global health – a major challenge of our time.
The Color of Precision Medicine by Shirley Sun,Zoe Ong Pdf
Will genome-based precision medicine fix the problem of race/ethnicity-based medicine? To answer this question, Sun and Ong propose the concept of racialization of precision medicine, defined as the social processes by which racial/ethnic categories are incorporated (or not) into the development, interpretation, and implementation of precision medicine research and practice. Drawing on interview data with physicians and scientists in the field of cancer care, this book addresses the following questions: Who are the racializers in precision medicine, how and why do they do it? Under what conditions do clinicians personalize medical treatments in the context of cancer therapies? The chapters elucidate different ways in which racialization occurs and reveal that there exists an inherent contradiction in the usage of race/ethnicity as precision medicine moves from bench to bedside. The relative resources theory is proposed to explain that whether race/ethnicity-based medicine will be replaced by genomic medicine depends on the resources available at the individual and systemic levels. Furthermore, this book expands on how racialization happens not only in pharmacogenomic drug efficacy studies, but also in drug toxicity studies and cost-effectiveness studies. An important resource for clinicians, researchers, public health policymakers, health economists, and journalists on how to deracialize precision medicine.
Richard D. Riley,Danielle van der Windt,Peter Croft,Karel G. M. Moons
Author : Richard D. Riley,Danielle van der Windt,Peter Croft,Karel G. M. Moons Publisher : Oxford University Press Page : 384 pages File Size : 55,7 Mb Release : 2019-01-17 Category : Medical ISBN : 9780192516657
Prognosis Research in Healthcare by Richard D. Riley,Danielle van der Windt,Peter Croft,Karel G. M. Moons Pdf
"What is going to happen to me?" Most patients ask this question during a clinical encounter with a health professional. As well as learning what problem they have (diagnosis) and what needs to be done about it (treatment), patients want to know about their future health and wellbeing (prognosis). Prognosis research can provide answers to this question and satisfy the need for individuals to understand the possible outcomes of their condition, with and without treatment. Central to modern medical practise, the topic of prognosis is the basis of decision making in healthcare and policy development. It translates basic and clinical science into practical care for patients and populations. Prognosis Research in Healthcare: Concepts, Methods and Impact provides a comprehensive overview of the field of prognosis and prognosis research and gives a global perspective on how prognosis research and prognostic information can improve the outcomes of healthcare. It details how to design, carry out, analyse and report prognosis studies, and how prognostic information can be the basis for tailored, personalised healthcare. In particular, the book discusses how information about the characteristics of people, their health, and environment can be used to predict an individual's future health. Prognosis Research in Healthcare: Concepts, Methods and Impact, addresses all types of prognosis research and provides a practical step-by-step guide to undertaking and interpreting prognosis research studies, ideal for medical students, health researchers, healthcare professionals and methodologists, as well as for guideline and policy makers in healthcare wishing to learn more about the field of prognosis.
The Ethics of Personalised Medicine by Jochen Vollmann,Verena Sandow,Jan Schildmann Pdf
In recent times, the phrase ’personalised medicine’ has become the symbol of medical progress and a label for better health care in the future. However, a controversial debate has developed around whether these promises of better, more personal and more cost-efficient medicine are realistic. This book brings together leading researchers from across Europe and North America, from both normative and empirical disciplines, who take a more critical view of the often encountered hype associated with personalised medicine. Partially drawing on a four year collaborative research project funded by the German Ministry for Education and Research, the book presents a multidisciplinary debate on the current state of research on the ethical, legal and social implications of personalised medicine. At a time when future health care is a topic of much discussion, this book provides valuable policy recommendations for the way forward. This study will be of interest to researchers from various disciplines including philosophy, bioethics, law and social sciences.
Identity, Invention, and the Culture of Personalized Medicine Patenting by Shubha Ghosh Pdf
This book provides an overview of developments in personalized medicine patenting and explores its normative implications to suggest policies to best regulate it.
