Life Death And Nitric Oxide

Author : Anthony R Butler,Rosslyn Nicholson
Publisher : Royal Society of Chemistry
Page : 168 pages
File Size : 45,9 Mb
Release : 2007-10-31
Category : Science
ISBN : 9781847551238

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Life, Death and Nitric Oxide by Anthony R Butler,Rosslyn Nicholson Pdf

Designated 'Molecule of the Year' in 1992 in recognition of its many biological roles, nitric oxide has wide significance in the world around us and the story of nitric oxide is still unfolding. This small and seemingly innocent molecule has for many years been known to play a significant role in both the creation of photochemical smogs and in the nitrogen cycle. It has an interesting chemistry as a metal ligand, and the bonding within the nitric oxide molecule has been extensively studied. More recently, the molecule has been in the spotlight for the role it plays in controlling blood flow, in the immune system and in brain activity. Life, Death and Nitric Oxide covers many of the topics relating to nitric oxide, from smog and catalytic converters to tumour growth, blood flow and Viagra, with the aim of finding out why such a simple molecule can do so much.

Author : Yaroslav Blume,D. J. Durzan,Petro Smertenko
Publisher : IOS Press
Page : 372 pages
File Size : 51,7 Mb
Release : 2006
Category : Medical
ISBN : 9781586035747

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Cell Biology and Instrumentation by Yaroslav Blume,D. J. Durzan,Petro Smertenko Pdf

Cellular processes, signaled by UV radiation, contribute to the behavior of plants under various stresses in the environment. This book aims to introduce developments and instrumentation for cell biology, to update our understanding of the effects of UV radiation, and to evaluate how plants use UV signals to protect against damage.

Author : S. Moncada,G. Nisticò,G. Bagetta,E. A. Higgs
Publisher : Unknown
Page : 0 pages
File Size : 44,8 Mb
Release : 2017-02-21
Category : Cell differentiation
ISBN : 0691654239

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Nitric Oxide and the Cell by S. Moncada,G. Nisticò,G. Bagetta,E. A. Higgs Pdf

Nitric oxide has proven to be a molecule with wide biological significance. It is involved in myriad actions which range from physiology to pathophysiology. One of the fundamental questions in relation to its biological relevance concerns the paradoxical nature of some of its actions. For example, there is a whole range of effects related to cytoprotection, cell proliferation, differentiation, and cell death. The way in which nitric oxide becomes involved in pathophysiology is slowly being elucidated. This volume contains a summary of the discussions that took place at the Second International Paraelios Symposium on Nitric Oxide research, and will make a significant contribution to this very exciting subject. Originally published in 1998. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Author : Louis J. Ignarro
Publisher : Academic Press
Page : 1017 pages
File Size : 41,8 Mb
Release : 2000-09-13
Category : Science
ISBN : 0080525032

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Nitric Oxide by Louis J. Ignarro Pdf

Nitric oxide (NO) is a gas that transmits signals in an organism. Signal transmission by a gas that is produced by one cell and which penetrates through membranes and regulates the function of another cell represents an entirely new principle for signaling in biological systems. NO is a signal molecule of key importance for the cardiovascular system acting as a regulator of blood pressure and as a gatekeeper of blood flow to different organs. NO also exerts a series of other functions, such as acting a signal molecule in the nervous system and as a weapon against infections. NO is present in most living creatures and made by many different types of cells. NO research has led to new treatments for treating heart as well as lung diseases, shock, and impotence. Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis. This book is the first comprehensive text on nitric oxide to cover all aspects--basic biology, chemistry, pathobiology, effects on various disease states, and therapeutic implications. Edited by Nobel Laureate Louis J. Ignarro, editor of the Academic Press journal, Nitric Oxide Authored by world experts on nitric oxide Includes an overview of basic principles of biology and chemical biology Covers principles of pathobiology, including the nervous system, cardiovascular function, pulmonary function, and immune defense

Author : Louis J. Ignarro,Bruce Freeman
Publisher : Academic Press
Page : 434 pages
File Size : 45,7 Mb
Release : 2017-08-03
Category : Science
ISBN : 9780128043196

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Nitric Oxide by Louis J. Ignarro,Bruce Freeman Pdf

Nitric Oxide: Biology and Pathobiology, Third Edition, provides information on nitric oxide, a signaling molecule of key importance for the cardiovascular system that regulates blood pressure and blood flow to different organs. With recent links to the role of nitric oxide in the expression of healthy benefits of controlled diet and aerobic exercise, and the reactions of nitric oxide that can impact cell signaling, this book provides a comprehensive resource during a time when increased research attention is being paid across the fields of biochemistry, chemistry, molecular biology, gene therapy, cell biology, immunology, pharmacology, neuroscience, and physiology. Includes perspectives from Jack Lancaster on the discovery of EDRF and nitric oxide Provides detailed coverage of the new gaseous signaling agents Features expanded coverage on the principles of biology, including nitric oxide synthases, nitrite and nitrate biology and pathobiology, and signaling mechanisms Incorporates expanded pathobiology coverage, including nitric oxide and cardiovascular function, obesity, diabetes, and erectile function/dysfunction

Author : Asghar Ghasemi,Khosrow Kashfi,Zahra Bahadoran
Publisher : Bentham Science Publishers
Page : 386 pages
File Size : 46,7 Mb
Release : 2022-12-01
Category : Medical
ISBN : 9789815079821

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The Role of Nitric Oxide in Type 2 Diabetes by Asghar Ghasemi,Khosrow Kashfi,Zahra Bahadoran Pdf

Type 2 diabetes (T2D) is a complex metabolic disorder characterized by impaired glucose metabolism and pancreatic β-cell dysfunction. No effective treatments are available for T2D, although there have been many developments in the therapeutic arena. Nitric oxide (NO) is an endocrine agent with multiple and important biological roles in most mammalian tissues. NO has emerged as a central regulator of energy metabolism and body composition. NO bioavailability is decreased in T2D. Several of the pharmaceuticals used in T2D affect the NO system and perhaps even more so by the drugs we use to treat diabetic cardiovascular complications. Experimental works in animal models of T2D show promising results with interventions aimed to increase NO signaling. However, translation into human studies has so far been less successful, but more large-scale prolonged studies are clearly needed to understand its role. This book is a collection of reviews that deal with the role of nitric oxide in type 2 diabetes, providing a unique overview of NO signaling, and pointing out key areas for more detailed research. The book includes contributions about the pathophysiology of T2D, a brief history of discovery and timeline of NO research, a comprehensive overview of impaired NO metabolism in T2D, precursors of NO (i.e., L-arginine, L-citrulline, nitrate, nitrites, and NO donors), NO and T2D from genetic points of view, NO and diabetic wound healing, NO and osteoporosis, NO and hyperuricemia, NO and Alzheimer’s Disease, therapeutic applications of NO and NO donors in T2D. The compilation is of great value to anyone interested in the biochemistry of NO and its relationship to diabetes.

Author : Benjamin Bonavida
Publisher : Springer Science & Business Media
Page : 250 pages
File Size : 47,6 Mb
Release : 2010-06-16
Category : Medical
ISBN : 1441914323

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Nitric Oxide (NO) and Cancer by Benjamin Bonavida Pdf

Nitric Oxide (NO) is a pleitropic, ubiquitous modulator of cellular functions. Aryl nitrite and glyceryl trinitrate, representative intravasadilators, were introduced as therapeutic agents more than a century ago for relief from acute attacks of angina. The vasodilator action is mediated by the release of NO following treatment. NO has important therapeutic applications in several diseases such as inflammatory diseases, erectile dysfunction, inflammation, pain and neural protective activity. However, the role of NO in cancer and its application in therapy has received little attention. This monograph will be the first to focus on studies that investigate the role of NO in tumor cell pathogenesis, growth, angiogenesis, response to cytotoxic therapies and NO translational applications in cancer therapy, alone or in conjunction with other therapies.

Author : Anonim
Publisher : World Health Organization
Page : 488 pages
File Size : 50,5 Mb
Release : 2010
Category : House & Home
ISBN : UCBK:C105261333

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WHO Guidelines for Indoor Air Quality by Anonim Pdf

This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in concentrations of health concern. The guidelines are targeted at public health professionals involved in preventing health risks of environmental exposures, as well as specialists and authorities involved in the design and use of buildings, indoor materials and products. They provide a scientific basis for legally enforceable standards.

Author : Robert K. Poole
Publisher : Academic Press
Page : 270 pages
File Size : 44,5 Mb
Release : 2011-12-20
Category : Medical
ISBN : 9780123876614

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Advances in Microbial Physiology by Robert K. Poole Pdf

Advances in Microbial Physiology is one of the most successful and prestigious series from Academic Press, an imprint of Elsevier. It publishes topical and important reviews, interpreting physiology to include all material that contributes to our understanding of how microorganisms and their component parts work. First published in 1967, it is now in its 59th volume. The Editors have always striven to interpret microbial physiology in the broadest context and have never restricted the contents to "traditional” views of whole cell physiology. Now edited by Professor Robert Poole, University of Sheffield, Advances in Microbial Physiology continues to be an influential and very well reviewed series. 2009 impact factor of 5.750, placing it 12th in the highly competitive category of microbiology Contributions by leading international scientists The latest research in microbial physiology

Author : Shahid Ul-Islam,Athar Adil Hashmi,Salman Ahmad Khan
Publisher : John Wiley & Sons
Page : 432 pages
File Size : 41,5 Mb
Release : 2020-07-08
Category : Science
ISBN : 9781119640424

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Advances in Metallodrugs by Shahid Ul-Islam,Athar Adil Hashmi,Salman Ahmad Khan Pdf

This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlights the application areas of newly discovered metallodrugs. It can prove beneficial for researchers, investigators and scientists whose work involves inorganic and coordination chemistry, medical science, pharmacy, biotechnology and biomedical engineering.

Author : Joseph Loscalzo,Joseph A. Vita
Publisher : Springer Science & Business Media
Page : 601 pages
File Size : 52,5 Mb
Release : 2000-03-29
Category : Medical
ISBN : 9781592590025

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Nitric Oxide and the Cardiovascular System by Joseph Loscalzo,Joseph A. Vita Pdf

Leading clinical and experimental investigators comprehensively review the chemistry, biochemistry, molecular biology, physiology, and pathophysiology of nitric oxide in the cardiovascular systems. These experts particularly illuminate nitric oxide biology, its cardiovascular pathophysiology, and its role in cardiovascular therapeutics. Topics also included are the development of nitric oxide donors for the treatment of myocardial ischemia and thrombosis, the development of gene therapeutic restoration of endothelial function in atherosclerosis, and the application of nitric oxide biology to investigative arenas in cardiovascular medicine. With its balanced presentation of basic and clinically relevant information, Nitric Oxide and the Cardiovascular System provides a comprehensive, authoritative guide for all those cardiovascular biologists, cardiologists, physiologists, and cardiovascular surgeons engaged in today's clinical or experimental research.

Author : Abhik Ghosh,Steffen Berg
Publisher : John Wiley & Sons
Page : 356 pages
File Size : 49,9 Mb
Release : 2014-08-18
Category : Science
ISBN : 9781118173985

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Arrow Pushing in Inorganic Chemistry by Abhik Ghosh,Steffen Berg Pdf

Involved as it is with 95% of the periodic table, inorganic chemistry is one of the foundational subjects of scientific study. Inorganic catalysts are used in crucial industrial processes and the field, to a significant extent, also forms the basis of nanotechnology. Unfortunately, the subject is not a popular one for undergraduates. This book aims to take a step to change this state of affairs by presenting a mechanistic, logical introduction to the subject. Organic teaching places heavy emphasis on reaction mechanisms - "arrow-pushing" - and the authors of this book have found that a mechanistic approach works just as well for elementary inorganic chemistry. As opposed to listening to formal lectures or learning the material by heart, by teaching students to recognize common inorganic species as electrophiles and nucleophiles, coupled with organic-style arrow-pushing, this book serves as a gentle and stimulating introduction to inorganic chemistry, providing students with the knowledge and opportunity to solve inorganic reaction mechanisms. • The first book to apply the arrow-pushing method to inorganic chemistry teaching • With the reaction mechanisms approach ("arrow-pushing"), students will no longer have to rely on memorization as a device for learning this subject, but will instead have a logical foundation for this area of study • Teaches students to recognize common inorganic species as electrophiles and nucleophiles, coupled with organic-style arrow-pushing • Provides a degree of integration with what students learn in organic chemistry, facilitating learning of this subject • Serves as an invaluable companion to any introductory inorganic chemistry textbook

Author : Dragan Uskoković,Velimir R. Radmilović
Publisher : Materials Research Society of Serbia
Page : 220 pages
File Size : 43,7 Mb
Release : 2018-08-13
Category : Technology & Engineering
ISBN : 9788691911133

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Programme and The Book of Abstracts / Twentieth Annual Conference YUCOMAT 2018, Herceg Novi, September 3-7, 2018 by Dragan Uskoković,Velimir R. Radmilović Pdf

Author : J. D. White,John Hugh McQuillen,George Jacob Ziegler,James William White,Edward Cameron Kirk,Lovick Pierce Anthony
Publisher : Unknown
Page : 380 pages
File Size : 43,6 Mb
Release : 1883
Category : Dentistry
ISBN : OSU:32436010389185

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The Dental Cosmos by J. D. White,John Hugh McQuillen,George Jacob Ziegler,James William White,Edward Cameron Kirk,Lovick Pierce Anthony Pdf

Author : Jeffrey D. Laskin,Debra L. Laskin
Publisher : CRC Press
Page : 408 pages
File Size : 47,5 Mb
Release : 1999-02-26
Category : Science
ISBN : 0824719654

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Cellular and Molecular Biology of Nitric Oxide by Jeffrey D. Laskin,Debra L. Laskin Pdf

"Provides the latest advances in the explosive growth of nitric oxide (NO) study-covering the behavior of this highly reactive molecule in a wide variety of physiologicial processes, including respiration, blood pressure, neurotransmission, nospecific host defense, and wound healing."