Author : Anonim
Publisher : Unknown
Page : 536 pages
File Size : 55,6 Mb
Release : 2011-04-11
Category : Electronic
ISBN : 1441914420
Nitric Oxide (No) and Cancer
Anonim
Nitric Oxide No And Cancer
Nitric Oxide No And Cancer Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Nitric Oxide No And Cancer book. This book definitely worth reading, it is an incredibly well-written.
Nitric Oxide (NO) and Cancer
Benjamin Bonavida
Author : Benjamin Bonavida
Publisher : Springer Science & Business Media
Page : 510 pages
File Size : 44,5 Mb
Release : 2010-06-16
Category : Medical
ISBN : 9781441914323
Nitric Oxide (NO) and Cancer by Benjamin Bonavida Pdf
Nitric Oxide (NO) is a pleitropic, ubiquitous modulator of cellular functions. Aryl nitrite and glyceryl trinitrate, representative intravasadilators, were introduced as therapeutic agents more than a century ago for relief from acute attacks of angina. The vasodilator action is mediated by the release of NO following treatment. NO has important therapeutic applications in several diseases such as inflammatory diseases, erectile dysfunction, inflammation, pain and neural protective activity. However, the role of NO in cancer and its application in therapy has received little attention. This monograph will be the first to focus on studies that investigate the role of NO in tumor cell pathogenesis, growth, angiogenesis, response to cytotoxic therapies and NO translational applications in cancer therapy, alone or in conjunction with other therapies.
Nitric Oxide in Health and Disease
Lucia Morbidelli,Benjamin Bonavida,Jordi Muntané
Author : Lucia Morbidelli,Benjamin Bonavida,Jordi Muntané
Publisher : Elsevier
Page : 366 pages
File Size : 47,6 Mb
Release : 2023-04-13
Category : Computers
ISBN : 9780443133435
Nitric Oxide in Health and Disease by Lucia Morbidelli,Benjamin Bonavida,Jordi Muntané Pdf
Nitric Oxide in Health and Disease: Therapeutic Applications in Cancer and Inflammatory Disorders presents updated information on the chemistry, signaling of newly derived therapeutic nitric oxide donors/inhibitors, and their complexes in liposomes or nanospheres in both pre-clinical and clinical activities. The book discusses many examples of research related to the application of novel therapeutic compounds that focus on a chemical—nitric oxide—and its applications that have been shown to exert significant therapeutic activities against various resistant cancers unresponsive to current treatments and different inflammatory diseases which continue to require novel treatments. This is a valuable resource for cancer researchers, oncologists, graduate students and researchers from medical and biomedical fields who want to know more about NO and its therapeutic applications in cancer and inflammatory diseases. Provides updated reviews on the chemistry and signaling of newly derived therapeutic nitric oxide (NO) donors/inhibitors and their complexes in liposomes or nanospheres in both pre-clinical and clinical activities Discusses the application of NO in monotherapy or in combination with conventional therapies in a variety of cancers and inflammatory diseases Encompasses real-world examples of recent research related to NO and cancer
Nitric Oxide and Cancer: Pathogenesis and Therapy
Benjamin Bonavida
Author : Benjamin Bonavida
Publisher : Springer
Page : 308 pages
File Size : 47,9 Mb
Release : 2015-05-12
Category : Medical
ISBN : 9783319136110
Nitric Oxide and Cancer: Pathogenesis and Therapy by Benjamin Bonavida Pdf
Advances in Nitric Oxide and Cancer is a volume that serves to give the latest research on nitric oxide (NO) and cancer. More specifically, the volume reviews significant advances in the application of NO-mediated drugs. The volume explores nitric oxide and its relationship to cancer spanning from its roles in the pathogenesis, prognosis, gene and protein modifications, regulation of resistance to cytotoxics, and therapeutic applications. With chapters written by leading experts, the volume addresses the burgeoning interest in a rapidly advancing field and provides a valuable resource to scientists who have initiated research as well as clinical investigations in their laboratories on the various roles of NO and cancer.
Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders
Lucia Morbidelli,Benjamin Bonavida
Author : Lucia Morbidelli,Benjamin Bonavida
Publisher : Academic Press
Page : 372 pages
File Size : 47,9 Mb
Release : 2019-02-09
Category : Medical
ISBN : 9780128172797
Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders by Lucia Morbidelli,Benjamin Bonavida Pdf
Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated reviews on the chemistry, signaling, pre-clinical and clinical activities on the role of nitric oxide donors/inhibitors used alone and in combination with other therapeutic agents for the treatment of a variety of diseases. This book examines various studies related to the application of novel therapeutic NO (donors/inhibitors) compounds in the treatment of various cancers. These studies have been shown to exert significant therapeutic activities against various cancers and various inflammatory diseases such as rheumatoid arthritis, Crohn’s disease, allergies, and asthma, where no current effective therapies exist. Pathologies based on functional and structural vascular alterations are also taken into consideration. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students. Provides readers with a clear overview of the recent findings and references as well as summaries, significant molecular pathways, and conclusions Discusses new ideas proposed and makes suggestions for further investigations that will advance the field Presents introductory and summary information on the contributions of the field, all the findings of the studies discussed, and projects future goals for research
Nitric Oxide (Donor/Induced) in Chemosensitization
Benjamin Bonavida
Author : Benjamin Bonavida
Publisher : Academic Press
Page : 250 pages
File Size : 50,6 Mb
Release : 2017-06-28
Category : Medical
ISBN : 9780128110218
Nitric Oxide (Donor/Induced) in Chemosensitization by Benjamin Bonavida Pdf
Nitric Oxide as a Chemosensitizing Agent, Volume One is the first book to describe several reviews by authoritative scientists and clinicians on novel findings in the reversal of drug resistant cancers by the combination treatment of Nitric Oxide and sub toxic concentrations of chemotherapeutic drugs that have been reported in both in vitro, in vivo and preclinical models. The book describes the various underlying chemical, molecular and genetic mechanisms by which NO and NO reactive species mediate the anti-cancer activity, thus reducing the threshold of drug resistance and enabling chemo therapeutic drugs to induce their cytotoxic activity and reversal of resistance. This book exposes scientists and clinicians to this highly beneficial topic for research investigations and pharmaceutical companies to new avenues for R&D. It is a valuable resource for cancer researchers, oncologists and members of several areas of the biomedical field who are interested in understanding how to use Nitric Oxide as a sensitizing agent for chemotherapy. Brings updated information as reviewed by experts in the field Presents expert analysis and summary of reported and novel findings and potential translational application in cancer patients Describes molecular mechanisms with new and helpful approaches that can be used in reader investigations
Anticancer Therapeutics
Sotiris Missailidis
Author : Sotiris Missailidis
Publisher : John Wiley & Sons
Page : 424 pages
File Size : 54,6 Mb
Release : 2008-10-13
Category : Science
ISBN : 9780470697030
Anticancer Therapeutics by Sotiris Missailidis Pdf
Written by the winner of the 2008 Mike Price Fellowship "This volume provides a comprehensive overview of the wealth of information now available in this important and fast-moving subject." Anticancer Research, November - December 2008 This book provides a clear introduction to the area, with an overview of the various drug design and development approaches for cancer therapeutics and their progress in today’s multidisciplinary approach to cancer treatment. Clearly structured throughout, the book not only provides information on currently used molecular treatment approaches, but also describes the various agents that are currently at various stages of development and clinical trials, thus making them the drugs of tomorrow. The book goes on to present current therapeutic regimes including their indications and side effects, as well as their position in the international market in terms of sales and development costs. Furthermore, coverage of our advancement in the understanding of cancer biology and how this has driven the drug discovery process is clearly discussed. Modern drug discovery aspects, through genomic, proteomic and metabolomic approaches are referred to as well as combinatorial chemistry techniques and discovery of chemotherapeutic agents from plant extracts, re-use of old drugs and drugs from other indications, or de novo rational drug design. Including contributions from leading experts in the field, this book provides the reader with a complete overview of the various types of therapeutic agents, current and emerging, as well as other aspects associated with anticancer therapy, drug design, resistance and clinical trials in oncology.
Nitric Oxide Synthase
Seyed Soheil Saeedi Saravi
Author : Seyed Soheil Saeedi Saravi
Publisher : BoD – Books on Demand
Page : 250 pages
File Size : 40,6 Mb
Release : 2017-05-17
Category : Science
ISBN : 9789535131632
Nitric Oxide Synthase by Seyed Soheil Saeedi Saravi Pdf
Nitric Oxide Synthase - Simple Enzyme-Complex Roles provides information on nitric oxide synthase, a biomolecule of key importance for the different biological systems, including central and peripheral nervous, cardiovascular, and reproductive systems. With recent links to the role of nitric oxide in the reactions that can impact cell signaling, and discoveries surrounding the complex role of nitric oxide synthase that have increased research attention across the fields of cell and molecular biology, physiology, pharmacology, toxicology, neuroscience, cardiology, urology, and endocrinology, this book tries to provide a comprehensive overview of biology/pathobiology of nitric oxide synthases and a perspective from possible therapeutic indication of the enzyme inhibitors.
Nitric Oxide: From Research to Therapeutics
Arunabha Ray,Kavita Gulati
Author : Arunabha Ray,Kavita Gulati
Publisher : Springer Nature
Page : 469 pages
File Size : 54,7 Mb
Release : 2023-03-07
Category : Medical
ISBN : 9783031247781
Nitric Oxide: From Research to Therapeutics by Arunabha Ray,Kavita Gulati Pdf
This book entitled "Nitric Oxide: From Research to Therapeutics" includes the most recent information about the role of Nitric Oxide (NO) in physiology, pathophysiology and its translation to therapeutics. The Editors are vastly experienced in the field of NO research. The international panels of contributors to the various chapters of the book are all well-established researchers and health professionals who have worked in different areas of NO physiology and pathophysiology, and have made a considerable impact in the field. The book is a comprehensive collection of the most recent information on NO as a physiological regulator and its diverse potential as a therapeutic target for the treatment for a variety of disease states. This compilation is aimed at professionals and students from both academia and the industry in the areas of basic biomedical and clinical sciences.
Nitric Oxide
Louis J. Ignarro
Author : Louis J. Ignarro
Publisher : Academic Press
Page : 1017 pages
File Size : 49,5 Mb
Release : 2000-09-13
Category : Science
ISBN : 0080525032
Nitric Oxide by Louis J. Ignarro Pdf
Nitric oxide (NO) is a gas that transmits signals in an organism. Signal transmission by a gas that is produced by one cell and which penetrates through membranes and regulates the function of another cell represents an entirely new principle for signaling in biological systems. NO is a signal molecule of key importance for the cardiovascular system acting as a regulator of blood pressure and as a gatekeeper of blood flow to different organs. NO also exerts a series of other functions, such as acting a signal molecule in the nervous system and as a weapon against infections. NO is present in most living creatures and made by many different types of cells. NO research has led to new treatments for treating heart as well as lung diseases, shock, and impotence. Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis. This book is the first comprehensive text on nitric oxide to cover all aspects--basic biology, chemistry, pathobiology, effects on various disease states, and therapeutic implications. Edited by Nobel Laureate Louis J. Ignarro, editor of the Academic Press journal, Nitric Oxide Authored by world experts on nitric oxide Includes an overview of basic principles of biology and chemical biology Covers principles of pathobiology, including the nervous system, cardiovascular function, pulmonary function, and immune defense
WHO Guidelines for Indoor Air Quality
Anonim
Author : Anonim
Publisher : World Health Organization
Page : 488 pages
File Size : 43,9 Mb
Release : 2010
Category : House & Home
ISBN : UCBK:C105261333
WHO Guidelines for Indoor Air Quality by Anonim Pdf
This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in concentrations of health concern. The guidelines are targeted at public health professionals involved in preventing health risks of environmental exposures, as well as specialists and authorities involved in the design and use of buildings, indoor materials and products. They provide a scientific basis for legally enforceable standards.
Nitric Oxide Donors
Amedea Seabra
Author : Amedea Seabra
Publisher : Academic Press
Page : 364 pages
File Size : 42,7 Mb
Release : 2017-03-17
Category : Medical
ISBN : 9780128134597
Nitric Oxide Donors by Amedea Seabra Pdf
Nitric Oxide Donors: Biomedical Applications and Perspectives presents the current state of art, challenges and innovations in the design of therapeutics nitric oxide donors with great impact in several aspects of human physiology and pathophysiology. Although considerable innovative progress has been achieved using Nitric Oxide donors in biomedical applications, certain drawbacks still need to be overcome to successfully translate these research innovations into clinical applications. This book encompasses several topics on nitric oxide such as its sources and biological properties; its performance in the cardiovascular and neurologic systems, in the human skin and its application in the treatment of neglected diseases, neurodegenerative disorders, and cancer. Additionally, it covers its role in inflammation and immunity, penile erection function, photodynamic therapy, antimicrobial activities. It also discusses the future of nitric oxide donors in combination with other therapeutic drugs, in implantable sensors, and nitric oxide releasing hydrogels and medical devices for topical applications. The book is a valuable source for researchers on different areas of biomedical field who are interested in the improvements that these molecules can make in the treatment of several conditions. Provides background information about biology and chemistry of nitric oxide Discusses the state-of-the-art in the design of nitric oxide releasing nanomaterials for biomedical applications Covers the usage of nitric oxide donors in the treatment of several conditions, such as cancer, human skin, cardiovascular system, and immunity Discusses the future of nitric oxide donors and their FDA approval
The Role of Nitric Oxide in Tumour Progression
Lorraine C. Jadeski
Author : Lorraine C. Jadeski
Publisher : Unknown
Page : 360 pages
File Size : 52,8 Mb
Release : 2003
Category : Electronic
ISBN : OCLC:1071867828
The Role of Nitric Oxide in Tumour Progression by Lorraine C. Jadeski Pdf
Artemisinin and Nitric Oxide
Qing-Ping Zeng
Author : Qing-Ping Zeng
Publisher : Springer
Page : 126 pages
File Size : 53,9 Mb
Release : 2015-06-23
Category : Science
ISBN : 9783662476888
Artemisinin and Nitric Oxide by Qing-Ping Zeng Pdf
This book discusses both the beneficial and harmful aspects of NO in biology and medicine, and also introduces the emerging discovery of artemisinin in antitumor, antibacterial infection, anti-inflammation, and antiaging contexts. In 1992 nitric oxide (NO) was voted “Molecule of the Year” by Science magazine, and the discovery of its physiological roles has led to Nobel Prize-winning work in neuroscience, physiology and immunology. The book explains why we should maintain a steady-state NO level that is derived from neuronal or epithelial NO synthase, and avoid the extremely high NO level resulting from inducible NO synthase. The book offers a valuable resource for medical chemists, clinicians, biologists and all those interested in health and disease.
Nitrite and Nitrate in Human Health and Disease
AnnMarie Kocher,Joseph Loscalzo
Author : AnnMarie Kocher,Joseph Loscalzo
Publisher : Springer Science & Business Media
Page : 306 pages
File Size : 54,9 Mb
Release : 2011-04-15
Category : Medical
ISBN : 9781607616160
Nitrite and Nitrate in Human Health and Disease by AnnMarie Kocher,Joseph Loscalzo Pdf
Nitrite and Nitrate in Human Health and Disease delivers a comprehensive review of nitrite and nitrate biology, from basic biochemistry to the complex physiology and metabolism of these two naturally occurring molecules in the human body. Well-organized and well referenced chapters cover the rich history of nitrite and nitrate, sources of exposure, and the physiological effects when consumed through foods containing nitrite and nitrate. The chapters are written by leading experts, all of whom share their research and perspectives in order to help define the context for benefits vs. any potential risks associated with nitrite and nitrate use, either through dietary ingestion or therapeutic dosing. This diverse collection of authors includes vascular biologists, physiologists, physicians, epidemiologists, cancer biologists, registered dieticians, chemists, and public health experts from five countries in both academia and government. Nitrite and Nitrate in Human Health and Disease provides a balanced view of nitric oxide biochemistry, and nitrite and nitrate biochemistry in physiology and in the food sciences.