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Author : Giangiacomo Torri,Jawed Fareed
Publisher : Unknown
Page : 1 pages
File Size : 44,7 Mb
Release : 2018
Category : Electronic books
ISBN : 3038429503
Looking Forward to the Future of Heparin: New Sources, Developments and Applications.
Author : Anonim
Publisher : Mdpi AG
Page : 288 pages
File Size : 47,8 Mb
Release : 2018-06-12
Category : Medical
ISBN : 303842949X
The year of 2016 marks the centenary celebration of the discovery of heparin, a very complex and heterogeneous macromolecule used as a lifesaving drug. Approaching the centenary, many meetings occurred. These events actualize, in addition to the historical aspects, the research themes of current interest. This Special Issue, devoted to heparin, aims to provide interdisciplinary information regarding such research by combining aspects of chemical structures to those of biological activity and collating contributions on the following issues. One of the currently relevant issues is the pharmaco-biological activities of heparins depleted of anticoagulant activity, involving research ranging from antitumor to antiviral applications. The technological processes to obtain synthetic heparins, or oligomers with defined structures, represent another current area of research, as well as heparin as part of nanostructured systems. Following renewed interest by industrial and social committees on the alternative sources of swine heparin, there is a great deal of research focused on the structural peculiarities and pharmaco-biological activities of heparin extracted from bovine tissues, which is being assessed by the FDA for inclusion in Pharmacopoeia. Similarly sheep sources are of particular interest for Asian countries.
Author : Gerald Litwack
Publisher : Academic Press
Page : 280 pages
File Size : 44,8 Mb
Release : 2019-02-22
Category : Science
ISBN : 9780128178430
Iron Metabolism, Volume 110, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more. Focuses on the newest aspects of hormone action in connection with diseases Lays the groundwork for the focus of new chemotherapeutic targets Represents reviews on emerging areas in hormone action, cellular regulators and signaling pathways
Author : Rebecca Lever,Barbara Mulloy,Clive P. Page
Publisher : Springer Science & Business Media
Page : 457 pages
File Size : 45,5 Mb
Release : 2012-05-08
Category : Medical
ISBN : 9783642230561
Heparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.
Author : Neri Serneri
Publisher : S. Karger AG (Switzerland)
Page : 242 pages
File Size : 47,8 Mb
Release : 1990
Category : Heparin
ISBN : CORNELL:31924060308297
Author : R. C. Becker
Publisher : Springer Science & Business Media
Page : 660 pages
File Size : 49,9 Mb
Release : 2008-01-21
Category : Medical
ISBN : 9780585337548
Teleologically, the hemostatic mechanism is among The of Coronary Thrombosis and the most fundamental yet complex physiologic pro- in essence, represents a heartfelt gift of cesses in humans. Early scientists and physicians were knowledge from a dedicated group of scientists and fascinated by the blood's ability to remain in a liquid clinicians, who collectively have set out on a mission state only to clot in response to vascular injury. The to minimize the societal impact of"hemostasis in the cellular and noncellular components of normal wrong place. " The book is divided into four distinct hemostasis took centuries to discover, and the intrica- sections: Part 1, Scientific Principles, lays down the cies of their delicate interactions are still being unrav- supporting foundation; Part 2, Clinical Application eled today. As is so often the case, an in-depth of Scientific Principles, places the knowledge base in appreciation of physiologic hemostasis, representing a a working perspective, directly applying science to basic life-sustaining sequence of events, paved the patient care; Part 3, New Dimensions, provides a way for understanding abnormal hemostasis or glimpse of tomorrow. Steering the field clear of se- pathologic thrombosis. Aristotle, Malpighi, and proclaimed victory and the dangers of complacency as Osier, representing but a few of the founding fathers we move into the 21st century, Part 4, Evolution of in the field, would undoubtedly be honored to see Thrombocardiology, focuses on laboratory standards, their observations form the template for lifesaving clinical trials, and drugs in development.
Author : Andrea Rounce,Karine Levasseur
Publisher : Univ. of Manitoba Press
Page : 252 pages
File Size : 40,7 Mb
Release : 2020-11-26
Category : Social Science
ISBN : 9780887559501
On 12 March 2020 Manitoba confirmed its first case of COVID-19. One week later, a province-wide state of emergency was declared, ushering in a new sense of urgency and rarely used government powers to protect Manitobans from the devastating global reach of the novel coronavirus. The wide-ranging impacts of the pandemic have touched every facet of Manitoba society and provincial responsibility, including health, economic development, social services, and government operations. COVID-19 has challenged the conventional policy-making process––complicating agenda setting and policy formulation, adoption, implementation, and evaluation––while governments have been under pressure to make swift decisions in life-and-death matters. New programs must address urgent and shifting health and economic realities, but also anticipate future waves of COVID-19 and potentially significant repercussions for future governments. "COVID-19 in Manitoba: Public Policy Responses to the First Wave" seeks to understand how Manitoba fared during the first months of the pandemic, with twenty-seven chapters that address key aspects of the pandemic and discuss how government policy can help lay the foundation for resiliency in the midst a continuing public-health crisis. This open-access volume is an essential resource for citizens and policy-makers alike, as it identifies policy gaps and successes of Manitoba’s early COVID response and points to strategies to prepare for future waves of the pandemic.
Author : A. Geibel,Hanjoerg Just,W. Kasper,S. Konstantinides
Publisher : Springer Science & Business Media
Page : 202 pages
File Size : 44,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642511905
The value of echocardiography in the diagnostic work-up of patients with suspected acute pulmonary embolism.- New developments in the thrombolytic therapy of venous thrombosis.- Mechanism of blood coagulation. Newer aspects of anticoagulant and antithrombotic therapy.MR-angiography in the diagnosis of pulmonary embolism.Scintigraphy-ventilation/perfusion scanning and imaging of the embolus.- Clinical course and prognosis of acute pulmonary embolism.- The molecular mechanisms of inherited thombophilia.
Author : Jacob V. Aranda
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 43,8 Mb
Release : 2017-12-01
Category : Medical
ISBN : 9780323552912
Dr. Aranda is an top expert in the area of pharmacology in the pediatric population. His issue has knowledgeable authors presenting clinical reviews on a wide variety of topics, from "hot areas " of drug therapy to drug abuse in children as well as current areas of debate in neonatal drug therapy. Articles are devoted to the following topics: New and Current Drug Therapies For Asthma In Children; Psychopharmacology Of Bipolar Disorders in Children and Adolescents; Designer Drug Abuse in School Children; Dietary Supplements in Children; Anticoagulant Therapies in Children; New Antimicrobials for Gram-Positive Infections in Children; Probiotics in Newborns And Children; Anticonvulsant Therapies in Newborns and Children; Immunomodulator Drug Therapies in Inflammatory Bowel Diseases in Children; Non-Steroidal Anti-Inflammatory Drugs in Newborns and Children; Metformin Use in Pre-Diabetic Children and Adolescents; Problems in Drug Dosing of Obese Children; Inhaled Drugs and Systemic Steroids for Bronchopulmonary Dysplasia; Antifungal Drugs in Newborns and Children; Antiviral Drugs In Newborns and Children; and Development of Drug Therapies for Newborns and Children. Readers will come away with the latest clinical information to help inform them when diagnosing and prescribing for children.
Author : United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Health
Publisher : Unknown
Page : 240 pages
File Size : 43,5 Mb
Release : 2008
Category : Cosmetics
ISBN : UOM:39015085459587
Author : Anonim
Publisher : Unknown
Page : 248 pages
File Size : 42,5 Mb
Release : 2010
Category : Electronic
ISBN : MINN:31951D03140315B
Author : Michael Szycher
Publisher : Unknown
Page : 1116 pages
File Size : 49,6 Mb
Release : 1983
Category : Medical
ISBN : UOM:39015009909964
Author : Jeff Coulter,Suzanne Coulter
Publisher : JNS Ministries
Page : 182 pages
File Size : 41,6 Mb
Release : 2022-01-22
Category : Religion
ISBN : 8210379456XXX
This is a story written from two different perspectives: one of a husband and one of a wife. Our individual lives started from two diverse worlds and combined to become one life in 1987. We considered ourselves the typical, normal suburban family. As we grew in our marriage and focused on raising our children, we were determined to do so with God in first place and the kids in church. Unfortunately, the circumstances of life came into play a few years into our marriage and developed into a near cataclysmic end to two wonderful relationships: Our marriage to each other and our marriage to Christ. Jeff and Suzanne Coulter have been married since 1987. Jeff Coulter was born in 1966 and is from Williamsburg, Ohio. A devout Christian throughout his early adulthood, Jeff reached a crossroad with the death of his mother in 1988 and found himself turning away from God. On April 22nd, 2014 Jeff was nearly killed in a head on collision. Beating the odds and surviving the crash, one week later Jeff suffered multiple pulmonary emboli. Only 1 out of 20 survive such a traumatic incident. Jeff slipped into a void of nothingness; the absolute absence of the presence of God. A void filled with demonic beings and symbolic icons of hell and death. Miraculously surviving the crash and emboli, God also delivered Jeff from alcoholism and chronic depression. Through it all there was his wife Suzanne at his side as if she belonged there by God’s own invitation. Driving him along the way. Jeff has since rededicated his life to Christ and now dedicates himself to church ministries, online ministries and authoring diverse books.
Author : Joseph D. Giusto
Publisher : Xlibris Corporation
Page : 43 pages
File Size : 46,9 Mb
Release : 2014-06-24
Category : Medical
ISBN : 9781499039795
This brief, yet interesting, history gives insight to the ancient materials and devices first applied to bodily drainage catheters and its leading to modern materials and modern vascular access systems. The latter are currently performing as feeding tubes, drug delivery and blood sampling, some directly into the heart, especially as used in the field of oncology. Elastomeric materials, natural and synthetic and flexible plastics, polyurethanes, polyethylene, polyvinylchloride, Teflon, and Nylon, all have been studied for vascular catheters. This scientific article also describes the clinical investigations by early leaders in this field, whose courage goes far beyond belief, some actually using their own bodies for experimentation.
Author : Bruce Ovbiagele
Publisher : Springer Nature
Page : 466 pages
File Size : 43,5 Mb
Release : 2024-07-02
Category : Electronic
ISBN : 9783031499630